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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00029987
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wgEx75.
Alternate IDs: WB-STRAIN:OP75, CGC_OP75
Notes: Made_by: modEncode|"Modern strain"|"wgEx75 [elt-3::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"|"wgIs75 [elt-3::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029987 Copy
http://www.wormbase.org/db/get?name=WBStrain00029986
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wgIs74.
Alternate IDs: WB-STRAIN:OP74, CGC_OP74
Notes: Made_by: modEncode|"wgIs74 [hlh-8::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029986 Copy
http://www.wormbase.org/db/get?name=WBStrain00029938
Source Database: WormBase (WB)
Affected Genes: WBGene00000445(ceh-22)
Genomic Alteration: WBGene00000445(ceh-22)
Availability: unknown
Source References: EMPTY
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:OK0029
Notes: Retired following removal of zero padded strain public_names.
Proper citation: RRID:WB-STRAIN:WBStrain00029938 Copy
http://www.wormbase.org/db/get?name=WBStrain00029934
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00003100(mab-3)
Genomic Alteration: WBGene00001864(him-5), WBGene00003100(mab-3)
Availability: available
Source References: PMID:38880276
Synonyms: mab-3(ot931[mab-3::GFP::3xFlag]) II; him-5 (e1490) V.
Alternate IDs: WB-STRAIN:OH15732, CGC_OH15732
Notes: GFP and 3xFlag tag inserted in endogenous mab-3 locus using the CRISPR SEC cassette (Dickinson 2015). sgRNA: ggtcaaaattatagatctt Insertion site: II: 9737290-9737291. Reference: Pereira L, et al. Elife. 2019 Jan 1;8. pii: e42078. doi: 10.7554/eLife.42078.
Proper citation: RRID:WB-STRAIN:WBStrain00029934 Copy
http://www.wormbase.org/db/get?name=WBStrain00029936
Source Database: WormBase (WB)
Affected Genes: WBGene00000483(che-1)
Genomic Alteration: WBGene00000483(che-1)
Availability: available
Source References: EMPTY
Synonyms: che-1(ot63 ot941[che-1::SEC-GFP::TEV::3xFLAG]) I.
Alternate IDs: WB-STRAIN:OH15815, CGC_OH15815
Notes: Made_by: Eduardo Leyva-Diaz|"ot941[che-1::SEC-GFP::TEV::3xFLAG]. Endogenous locus of che-1 carrying ot63 null alllele and tagged with GFP (che-1::SEC-GFP::TEV::3xFLAG). che-1(ot63) is a loss of function allele which carries a (Cys255Tyr) missense mutation in the fourth Zn finger domain of CHE-1. Reference: Chang S, et al. Genes Dev. 2003 Sep 1;17(17):2123-37."
Proper citation: RRID:WB-STRAIN:WBStrain00029936 Copy
http://www.wormbase.org/db/get?name=WBStrain00029935
Source Database: WormBase (WB)
Affected Genes: WBGene00001867(him-8)|WBGene00012832(dmd-3)
Genomic Alteration: WBGene00001867(him-8), WBGene00012832(dmd-3)
Availability: available
Source References: PMID:37039075
Synonyms: dmd-3(ot932[dmd-3::GFP::3xFlag]); him-8 (e1489) IV.
Alternate IDs: WB-STRAIN:OH15733, CGC_OH15733
Notes: DMD-3::GFP endogenous tag|"GFP and 3xFlag tag inserted in endogenous dmd-3 locus using the CRISPR SEC cassette (Dickinson 2015). sgRNA: accctttcagccgtattgt Insertion site: V: 19650564-19650565. Reference: Pereira L, et al. Elife. 2019 Jan 1;8. pii: e42078. doi: 10.7554/eLife.42078."
Proper citation: RRID:WB-STRAIN:WBStrain00029935 Copy
http://www.wormbase.org/db/get?name=WBStrain00029931
Source Database: WormBase (WB)
Affected Genes: WBGene00006756(unc-17)
Genomic Alteration: WBGene00006756(unc-17)
Availability: available
Source References: EMPTY
Synonyms: unc-17(ot907[unc-17::mKate2::3xflag]) IV.
Alternate IDs: WB-STRAIN:OH15568, CGC_OH15568
Notes: Superficially wild-type. mKate2 and 3xFlag tag added to endogenous unc-17 locus. unc-17::mKate2 labels all cholinergic neurons in the nervous system. Reference: Pereira L, et al. Elife. 2019 Jan 1;8. pii: e42078. doi: 10.7554/eLife.42078.
Proper citation: RRID:WB-STRAIN:WBStrain00029931 Copy
http://www.wormbase.org/db/get?name=WBStrain00029927
Source Database: WormBase (WB)
Affected Genes: WBGene00016216(pals-22)
Genomic Alteration: WBGene00016216(pals-22)
Availability: available
Source References: EMPTY
Synonyms: pals-22(ot811) III; otIs381 V
Alternate IDs: WB-STRAIN:OH15179, CGC_OH15179
Notes: Made_by: Eduardo Leyva-Diaz|"otIs381 [ric-19p(prom6)::2xNLS::GFP + elt-2::DsRed] V. pals-22(ot811) mutant shows transgene-silencing phenotype. Pan-neuronal nuclear GFP expression. Reference: Stefanakis N., Carrera I., Hobert O. Neuron. 2015 Aug 19;87(4):733-50. Leyva-Daz E, et al. Genetics (2017), 207(2):529-545."
Proper citation: RRID:WB-STRAIN:WBStrain00029927 Copy
http://www.wormbase.org/db/get?name=WBStrain00029926
Source Database: WormBase (WB)
Affected Genes: WBGene00016216(pals-22)
Genomic Alteration: WBGene00016216(pals-22)
Availability: available
Source References: EMPTY
Synonyms: pals-22(ot810) III; otIs381 V.
Alternate IDs: WB-STRAIN:OH15178, CGC_OH15178
Notes: Made_by: Eduardo Leyva-Diaz|"otIs381 [ric-19p(prom6)::2xNLS::GFP + elt-2::DsRed] V. Pan-neuronal nuclear GFP expression. pals-22(ot810) mutant shows transgene-silencing phenotype. Reference: Stefanakis N., Carrera I., Hobert O. Neuron. 2015 Aug 19;87(4):733-50. Leyva-Daz E, et al. Genetics (2017), 207(2):529-545."
Proper citation: RRID:WB-STRAIN:WBStrain00029926 Copy
http://www.wormbase.org/db/get?name=WBStrain00029928
Source Database: WormBase (WB)
Affected Genes: WBGene00006818(unc-86)
Genomic Alteration: WBGene00006818(unc-86)
Availability: available
Source References: EMPTY
Synonyms: unc-86(ot893[unc-86::3xFlag::mNeonGreen::AID]) III.
Alternate IDs: WB-STRAIN:OH15227, CGC_OH15227
Notes: Made_by: Eduardo Leyva-Diaz|"unc-86(ot893) is a CRISPR/Cas9 engineered translational reporter (nuclear mNeonGreen expression). Endogenous unc-86 locus is tagged 3xFlag::mNeonGreen::AID (Auxin Inducible Degron) at the 3' end. The mNeonGreen::AID cassette was inserted right before the stop codon of the unc-86 locus, using a guide RNA that targets a sequence overlapping the unc-86 locus STOP codon (target sequence: GGATTCTTTGATTAGTTTCG). Reference: Serrano-Saiz E, (2018). BRN3-type POU homeobox genes maintain the identity of mature postmitotic neurons in nematodes and mice. Curr Biol (in press)."
Proper citation: RRID:WB-STRAIN:WBStrain00029928 Copy
http://www.wormbase.org/db/get?name=WBStrain00029922
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00004010(pha-1)
Genomic Alteration: WBGene00001864(him-5), WBGene00004010(pha-1)
Availability: available
Source References: EMPTY
Synonyms: pha-1(e2123) III; him-5(e1490) V; otEx7020.
Alternate IDs: WB-STRAIN:OH15128, CGC_OH15128
Notes: otEx7020 [srg-64p::GFP + pha-1(+)]. Maintain at 25C to select for transgenic array. Reference: Vidal B, et al. (2018) PLoS Biol 16(1): e2004218.
Proper citation: RRID:WB-STRAIN:WBStrain00029922 Copy
http://www.wormbase.org/db/get?name=WBStrain00029924
Source Database: WormBase (WB)
Affected Genes: WBGene00004010(pha-1)
Genomic Alteration: WBGene00004010(pha-1)
Availability: available
Source References: EMPTY
Synonyms: pha-1(e2123) III; otEx7036.
Alternate IDs: WB-STRAIN:OH15144, CGC_OH15144
Notes: Made_by: Eduardo Leyva-Diaz|"otEx7036 [pals-22p::GFP::unc-54 3'UTR + pha-1(+)]. Transcriptional reporter containing pals-22 promoter (coordinates -791 to -1 from start). Maintain at 25C to select for otEx7036. Reference: Leyva-Daz E, et al. Genetics (2017), 207(2):529-545."
Proper citation: RRID:WB-STRAIN:WBStrain00029924 Copy
http://www.wormbase.org/db/get?name=WBStrain00027384
Source Database: WormBase (WB)
Affected Genes: WBGene00000424(ced-10)|WBGene00001074(dpy-13)|WBGene00002990(lin-1)
Genomic Alteration: WBGene00000424(ced-10), WBGene00001074(dpy-13), WBGene00002990(lin-1)
Availability: available
Source References: EMPTY
Synonyms: ced-10(n3417)/lin-1(e1275) dpy-13(e184) IV.
Alternate IDs: WB-STRAIN:MT10869, CGC_MT10869
Notes: Heterozygotes are semi-Dpy. Throws DpyLins and DTC-defective progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00027384 Copy
http://www.wormbase.org/db/get?name=WBStrain00027386
Source Database: WormBase (WB)
Affected Genes: WBGene00000426(ced-12)
Genomic Alteration: WBGene00000426(ced-12)
Availability: available
Source References: PMID:33759761
Synonyms: ced-12(n3261) I.
Alternate IDs: WB-STRAIN:MT11068, CGC_MT11068
Notes: Defects in engulfment, persistent cell coprses observed in embyros, larvae, and adult hermaphrodite gonads. Distal tip cell migration defects.|"WBStrain provided so WBPaper00061198 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00027386 Copy
http://www.wormbase.org/db/get?name=WBStrain00027387
Source Database: WormBase (WB)
Affected Genes: WBGene00013096(mcd-1)
Genomic Alteration: WBGene00013096(mcd-1)
Availability: available
Source References: EMPTY
Synonyms: mcd-1(n3376) II; nIs106 X.
Alternate IDs: WB-STRAIN:MT11090, CGC_MT11090
Notes: nIs106 [lin-11::GFP + lin-15(+)] X. Egl, Him. lin-11::GFP expressed in vulva, head neurons, VC neurons. n3376 enhances ced-3(n2427). Reference: (2007) Genetics 175(4)::1719-33.
Proper citation: RRID:WB-STRAIN:WBStrain00027387 Copy
http://www.wormbase.org/db/get?name=WBStrain00027380
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:MT10729
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00027380 Copy
http://www.wormbase.org/db/get?name=WBStrain00027382
Source Database: WormBase (WB)
Affected Genes: WBGene00001077(dpy-18)|WBGene00003047(lis-1)
Genomic Alteration: WBGene00001077(dpy-18), WBGene00003047(lis-1)
Availability: available
Source References: EMPTY
Synonyms: dpy-18(e364) lis-1(n3334) III/eT1 (III;V).
Alternate IDs: WB-STRAIN:MT10784, CGC_MT10784
Notes: Heterozygotes are WT and segregate WT, Unc-36 (eT1 homozygotes), and dpy-18 lis-1 homozygotes which are Mel, Unc, Egl, and Dpy.
Proper citation: RRID:WB-STRAIN:WBStrain00027382 Copy
http://www.wormbase.org/db/get?name=WBStrain00027377
Source Database: WormBase (WB)
Affected Genes: WBGene00006562(tdc-1)
Genomic Alteration: WBGene00006562(tdc-1)
Availability: available
Source References: PMID:37155851
Synonyms: tdc-1(n3421) II.
Alternate IDs: WB-STRAIN:MT10549, CGC_MT10549
Notes: Forages while backing. Deletion in L-aromatic amino acid decarboxylase with homology to histidine decarboxylase. Reference: Alkema M, et al. Neuron. 2005 Apr 21;46(2):247-60.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00027377 Copy
http://www.wormbase.org/db/get?name=WBStrain00027378
Source Database: WormBase (WB)
Affected Genes: WBGene00002997(lin-8)
Genomic Alteration: WBGene00002997(lin-8)
Availability: available
Source References: EMPTY
Synonyms: lin-8(n2731) II.
Alternate IDs: WB-STRAIN:MT10591, CGC_MT10591
Notes: Made_by: Ewa Davidson|"SynMuv. Reference: Andersen EC, et al. Genetics. 2008 Aug;179(4):2001-12. Harrison MM, et al. Genetics. 2007 May;176(1):255-71."
Proper citation: RRID:WB-STRAIN:WBStrain00027378 Copy
http://www.wormbase.org/db/get?name=WBStrain00027374
Source Database: WormBase (WB)
Affected Genes: WBGene00003004(lin-15)|WBGene00003036(lin-53)|WBGene00006808(unc-76)|WBGene00023498(lin-15A)
Genomic Alteration: WBGene00003004(lin-15), WBGene00003036(lin-53), WBGene00006808(unc-76), WBGene00023498(lin-15A)
Availability: available
Source References: EMPTY
Synonyms: lin-53(n833) I; unc-76(e911) V; lin-15A(n767) X; nEx998.
Alternate IDs: WB-STRAIN:MT10408, CGC_MT10408
Notes: nEx998 [lin-53::GFP + unc-76(+)]. Pick non-Unc, non-Muv to maintain.
Proper citation: RRID:WB-STRAIN:WBStrain00027374 Copy
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