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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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WKY-Tph1em3Mcwi Resource Report Resource Website |
RRID:RGD_13208231 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Tph1 gene of WKY/NCrl rat embryos. The resulting mutation is a 1-bp insertion in the exon 4 of the Tph1 gene. Contact MCW rat distribution at [email protected] | 13208231 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13208231 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SS-Tlr4em1Mcwi Resource Report Resource Website |
RRID:RGD_13793372 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Tlr4 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp deletion in exon 2. Contact MCW rat distribution at [email protected] | 13793372 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13793372 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
T2DN-F2rem1Mcwi Resource Report Resource Website |
RRID:RGD_13799350 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of F2r gene in the T2DN/Mcwi embryos. Contact MCW rat distribution at [email protected] | 13799350 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-10-10) | 13799350 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SS-P2ry2em7Mcwi Resource Report Resource Website |
RRID:RGD_13800871 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the P2ry2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 115-bp deletion in exon 3 in the P2ry2 gene. Contact MCW rat distribution at [email protected] | 13800871 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13800871 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SS-Prltm1(PRL)Mcwi Resource Report Resource Website |
RRID:RGD_13800875 | Rattus norvegicus | CRISPR/Cas9 and plasmid donor containing floxed human prolactin cDNA were used to insert the human cDNA into the start coden of rat prolactin gene Contact MCW rat distribution at [email protected] | 13800875 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13800875 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
LH-Chr 17LN-C17h6orf52em2Mcwi Resource Report Resource Website |
RRID:RGD_13800877 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a net 10-bp insertion in exon 2 of rat C17h6orf52. | 13800877 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2026-01-14) | 13800877 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SS-Avpr2em5Mcwi Resource Report Resource Website |
RRID:RGD_13793378 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Avpr2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 9-bp deletion in exon 2. Contact MCW rat distribution at [email protected] | 13793378 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-10-03) | 13793378 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
DA-Tph1em4Mcwi Resource Report Resource Website |
RRID:RGD_13793374 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Tph1 gene of DA/MolTac rat embryos. The resulting mutation is a 1-bp deletion in exon 4. Contact MCW rat distribution at [email protected] | 13793374 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-10-03) | 13793374 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SS-Cgnl1em1Mcwi Resource Report Resource Website |
RRID:RGD_13799346 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 80-bp deletion on exon 2 of Cgnl1 gene in SS/JrHsdMcwi embryos Contact MCW rat distribution at [email protected] | 13799346 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-10-10) | 13799346 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Cd55em6Mcwi Resource Report Resource Website |
RRID:RGD_13207492 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 4-bp deletion of exon 2 in the rat Cd55 gene of Crl:SD embryos. Contact MCW rat distribution at [email protected] | 13207492 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-08-02) | 13207492 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
F344-Il2rgem1Iexas Resource Report Resource Website |
RRID:RGD_13464263 | Rattus norvegicus | This strain was established by CRISPR/Cas9 targeting rat Il2rg gene using electroporation. background strain: F344/Jcl. This strain shows severe combined immunodeficiency (SCID) caused by 5-bp deletion of Il2rg gene. This strain grows normally under SPF condition. National BioResource Project for the Rat in Japan | 13464263 | mutant | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Sperm (as of 2018-01-02) | 13464263 | RGD | 2026-11-07 12:23:25 | 0 | |||||
|
SS-Kcnj13em1Mcwi Resource Report Resource Website |
RRID:RGD_13207497 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Kcnj13 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp insertion of exon 2 in the Kcnj13 gene. Contact MCW rat distribution at [email protected] | 13207497 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13207497 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SS-P2ry2em6Mcwi Resource Report Resource Website |
RRID:RGD_13800869 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the P2ry2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 132-bp deletion in exon 3 in the P2ry2 gene. Contact MCW rat distribution at [email protected] | 13800869 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13800869 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Fhem1+/+ Resource Report Resource Website |
RRID:RGD_13792795 | Rattus norvegicus | A pair of TALENs targeting exon 1 of the Fh gene was injected into SD embryos to create Fh knock out mutants. The resulting mutation was an 11-bp deletion (acacctttggt) on exon 1 that caused premature stop of FH protein. Breeding of Fh +/- rats was done to generate wildtype (Fh+/+)and Fh (+/-). No homozygous mutant were observed. | 13792795 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13792795 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SS-Cgnl1em2Mcwi Resource Report Resource Website |
RRID:RGD_13799348 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 88-bp deletion on exon 2 of Cgnl1 gene in SS/JrHsdMcwi embryos Contact MCW rat distribution at [email protected] | 13799348 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-10-10) | 13799348 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Fhem1+/- Resource Report Resource Website |
RRID:RGD_13792794 | Rattus norvegicus | A pair of TALENs targeting exon 1 of the Fh gene was injected into SD embryos to create Fh knock out mutants. The resulting mutation was an 11-bp deletion (acacctttggt) on exon 1 that caused premature stop of FH protein. No homozygous -/- mutant was revealed in litters. | 13792794 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13792794 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
WI-Slc6a4m1Hubr+/- Resource Report Resource Website |
RRID:RGD_14390069 | Rattus norvegicus | The Slc6a4 knockout rat was generated by target-selected ENU-induced mutagenesis. An ENU-induced premature stop codon in exon 3 of the Slc6a4 gene in a female rat (Wistar from Crl) was identified.The heterozygoous mutant rats were used to generate homozygous Slc6a4 knock out rats. | 14390069 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 14390069 | RGD | 2026-11-07 12:23:27 | 0 | |||||
|
SD-Muc1em1Cgen Resource Report Resource Website |
RRID:RGD_127345097 | Rattus norvegicus | The Muc1 knock out Sprague Dawley rats were produced by targeted gene mutation at rat Muc1 gene. The deletion was made by microinjection of TALENs and located in the exon 1 of rat Muc1 gene (Gen Bank: NM_012602.1). Genotyping was performed by PCR of tail DNA using primers specific for the rat MUC1 gene with forward primer 5′-CTAGCAAGCCTAAAAGGTGAGAGGT-3′ and reverse primer 5′-ACGAAGAGCATTTGCCTACTC-3′, followed by DNA sequencing analysis. Cyagen Biosciences Inc., Guangzhou, China | 127345097 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 127345097 | RGD | 2026-11-07 12:23:27 | 0 | |||||
|
F344-Prkar1bem2Tua Resource Report Resource Website |
RRID:RGD_150519901 | Rattus norvegicus | CRISPR/Cas9 system containing guide RNAs targeting exon 2 and intron 2 were introduced into the F344/Stm embryos using a super electroporator NEPA 2. This mutant strain F344-Prkar1bem2Tua carried a 13-bp frameshift deletion in exon2 creating a premature stop codon in the Prkar1b transcripts. Expression levels of Prkar1b transcripts and protein are significantly decreased in the mutants. | 150519901 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 150519901 | RGD | 2026-11-07 12:23:27 | 0 | |||||
|
SD-Hamp em1Jfcol +/- Resource Report Resource Website 1+ mentions |
RRID:RGD_36174030 | Rattus norvegicus | Hamp KO, Sprague-Dawley rats were generated by Transposagen Biopharmaceuticals (Lexington, KY). Four different genetically engineered rat lines, each with different sized Hamp deletions (with or without concurrent insertions), were created using TALEN technology. SD-Hamp em1Jfcol +/- (RGD: 36174030) is heterozygous carrying a 169-bp deletion between exons 2 & 3 of rat Hamp gene. Rat Resource & Research Center (RRRC) | 36174030 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-07-28) | 36174030 | RGD | 2026-11-07 12:23:27 | 1 |
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