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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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WI-Tg(Fos-LacZ)BhopeRrrc Resource Report Resource Website |
RRID:RRRC_00952 | Rattus norvegicus | The lacZ gene was inserted between NcoI and SalI sites in exon 4 of the murine Fos gene . The linearized DNA was then microinjected into fertilized rat oocytes and line 1-8 was chosen for continuation. Initial SD rats were then bred onto Wistar background for >10 generations at NIDA IRP (Bruce Hope lab) Rat Resource and Research Center | 00952 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_151356950, 151356950, RRRC_952, RRRC_0952, RRRC_00952 | 2026-09-19 04:08:54 | 0 | |||||
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SD-Tg(CAG-loxP-mCherry-loxP-EGFP)1Qly Resource Report Resource Website |
RRID:RRRC_00844 | Rattus norvegicus | A CAG-loxP-mCherry-loxP-EGFP cassette was injected into SD zygote to generate this line. The integration site is not determined. This transgenic line could be mated to other rat lines that express Cre/CreER for lineage tracing. Rat Resource and Research Center | 00844 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695032, 14695032, RRRC_844, RRRC_0844, RRRC_00844 | 2026-09-19 04:08:54 | 0 | |||||
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LE-Tg(DIO-mCherry)2Ottc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00687 | Rattus norvegicus | The transgene contains Cre recombinase reporter rat expressing mCherry driven by the EF1 alpha promoter. A Rrrc substrain available at Rat Resource and Research Center | 00687 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521660, 150521660, RRRC_687, RRRC_0687, RRRC_00687 | 2026-09-19 04:08:54 | 3 | |||||
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WKY-Tg(Eef1a1-GFP)Tja Resource Report Resource Website |
RRID:RRRC_00780 | Rattus norvegicus | Transgenic strain using Sleeping Beauty transposon germline transgenesis, ubiquitously expressing green fluorescent protein (GFP) under the rat eukaryotic translation elongation factor 1 alpha (Eef1a1) promoter. Two integration sites located on chromosome 8:28170658 and chromosome 1:276465837, both located in intronic gene areas, Jam3 (RGD:1303248) intron 1 and Vti1a (RGD:621490) intron 6, respectively. The Jam3 intron 1 is 51bp long, and the transgene resides at 37kb from exon 1 and 13kb from exon 2. In Vti1a intron 6, 102 bp long, the transgene is located at 81.4 kb from exon 5 and 21 kb from exon 6. Rat Resource and Research Center | 00780 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695060, 14695060, RRRC_780, RRRC_0780, RRRC_00780 | 2026-09-19 04:08:53 | 0 | |||||
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SD-Tg(Adra1a)Vccr Resource Report Resource Website |
RRID:RRRC_00756 | Rattus norvegicus | Cardiac specific overexpression of the alpha 1A adrenergic receptor, 40 fold overexpression of the receptor Rat Resource and Research Center | 00756 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11040563, 11040563, RRRC_756, RRRC_0756, RRRC_00756 | 2026-09-19 04:08:53 | 0 | |||||
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LE-Tg(GFAP-TK)Hcam Resource Report Resource Website |
RRID:RRRC_00764 | Rattus norvegicus | random insertion of human GFAP promoter driving herpes simples virus thymidine kinase Rat Resource and Research Center | 00764 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11087549, 11087549, RRRC_764, RRRC_0764, RRRC_00764 | 2026-09-19 04:08:53 | 0 | |||||
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F344-Tg(Cx3cr1-cre/ERT2)3OttcRrrc Resource Report Resource Website |
RRID:RRRC_00927 | Rattus norvegicus | The transgene of LE-Tg(Cx3cr1-cre)3Ottc (RGD: 13441557) was crossed onto Fischer344 background by backcrossing the hybrid to Fischer344 and select for the presence of transgene. The donor LE transgenic was generated by microinjection of LE embyos with a BAC DNA containing the Cx3cr1-cre/ERT2 transgene which is composed of cre/ERT2 recombinase gene driven by the rat genomic Cx3cr1promoter. Rat Resource and Research Center | 00927 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_155641246, 155641246, RRRC_927, RRRC_0927, RRRC_00927 | 2026-09-19 04:08:54 | 0 | |||||
|
SD-Tg(DIO-mCherry)2OttcRrrc Resource Report Resource Website |
RRID:RRRC_00928 | Rattus norvegicus | The transgene contains Cre recombinase reporter rat expressing mCherry driven by the EF1 alpha promoter. Expresses mCherry in cells of the brain transduced with a Cre-expression virus. Currently in SD background generated by backcrossing to LE-Tg(DIO-mCherry)2Ottc Rat Resource and Research Center | 00928 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521661, 150521661, RRRC_928, RRRC_0928, RRRC_00928 | 2026-09-19 04:08:54 | 0 | |||||
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SD-Tg(Thy1-APPDI)BWevn Resource Report Resource Website |
RRID:RRRC_00974 | Rattus norvegicus | This novel transgenic rat produces low levels of human familial cerebral amyloid angiopath (CAA) Dutch/Iowa E22Q/D23N mutant amyloid beta protein in brain and recapitulates many of the pathologic aspects of human small-vessel CAA. A pcDNA3 vector containing 2.1 kb of human APP (isoform 770) cDNA was used to introduce the mutations Swedish K670N/M671L, Dutch E693Q, and Iowa D694N using the QuikChange kit. The APP770-SwDI cDNA was amplified by PCR using primers containing the NheI five linker and SacII three linker. The PCR product of the APP770-SwDI was subcloned between exons II and IV of a Thy1.2 expression cassette using NheI and SacII restriction sites. The completed construct was microinjected into pronuclei of Sprague-Dawley single-cell embryos. Founder rats were identified by Southern blot analysis of tail DNA. Transgenic offspring were determined by PCR analysis of tail DNA. All subsequent analyses were performed with hemizygous transgenic rats. Rat Resource and Research Center | 00974 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryorecovery (as of 2025-10-30) | RGD_626168255, 626168255, RRRC_974, RRRC_0974, RRRC_00974 | 2026-09-19 04:08:54 | 0 | |||||
|
SD-Tg(Fos-LacZ)Bhope Resource Report Resource Website 1+ mentions |
RRID:RRRC_00865 | Rattus norvegicus | The lacZ gene was inserted between NcoI and SalI sites in exon 4 of the murine Fos gene . The linearized DNA was then microinjected into fertilized rat oocytes and line 1-8 was chosen for continuation. Rats were rederived from frozen embryos in 2002 and bred onto SD background for >35 generations at NIDA IRP (Bruce Hope lab) Rat Resource and Research Center | 00865 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14390082, 14390082, RRRC_865, RRRC_0865, RRRC_00865 | 2026-09-19 04:08:53 | 2 | |||||
|
LE-Tg(DIO-iRFP)3Ottc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00747 | Rattus norvegicus | The transgene contains Cre recombinase reporter rat expressing the red fluorescent protein gene (iRFP) driven by the EF1 alpha promoter. Optogenetics and Transgenic Technology Core, Rat Resource and Research Center | 00747 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm; Cryorecovery | RGD_9588559, 9588559, RRRC_747, RRRC_0747, RRRC_00747 | 2026-09-19 04:08:53 | 1 | |||||
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SD-Tg(ACE2)058Bryd Resource Report Resource Website 1+ mentions |
RRID:RRRC_01012 | Rattus norvegicus | Genetic Alteration(s):human ACE2 gene under expression of the human ACE2 promoter. Eight copies of the transgene are randomly integrated into an as yet unknown insertion site. Deposited at Rat Resource and Research Center | 01012 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo (as of 2025-11-06) | RGD_629006611, 629006611, RRRC_1012, RRRC_01012 | 2026-09-19 04:08:54 | 1 | |||||
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FVB.B10ScSn-Dmdmdx Tg(Myh6-DMD*)271Dua/Mmjax Resource Report Resource Website |
RRID:MMRRC_041198-JAX | Mus musculus | Research areas: Cardiovascular, Cell Biology, Models for Human Disease; Mutation Type: Transgenic ; Collection: | kyphosis [MP:0000160]| increased monocyte cell number [MP:0000220]| decreased neutrophil cell number [MP:0000222]| enlarged heart [MP:0000274]| abnormal myocardial fiber morphology [MP:0000278]| decreased granulocyte number [MP:0000334]| abnormal hindlimb morphology [MP:0000556]| absent CD8-positive [MP:0000727]| alpha-beta T cells [MP:0000729]| abnormal myogenesis [MP:0000733]| abnormal muscle development [MP:0000745]| tremors [MP:0000746]| weakness [MP:0000747]| muscle weakness [MP:0000748]| progressive muscle weakness [MP:0000749]| muscle degeneration [MP:0000750]| abnormal muscle regeneration [MP:0000751]| myopathy [MP:0000752]| dystrophic muscle [MP:0000759]| abnormal skeletal muscle morphology [MP:0000761]| thin diaphragm muscle [MP:0001053]| abnormal neuromuscular synapse morphology [MP:0001262]| decreased body weight [MP:0001263]| weight loss [MP:0001264]| increased body size [MP:0001265]| decreased body size [MP:0001402]| hypoactivity [MP:0001405]| impaired coordination [MP:0001406]| abnormal gait [MP:0001407]| short stride length [MP:0001504]| abnormal posture [MP:0001515]| abnormal grip strength [MP:0001732]| postnatal growth retardation [MP:0001853]| heart inflammation [MP:0001921]| reduced fertility [MP:0001923]| reduced female fertility [MP:0001951]| abnormal breathing pattern [MP:0001953]| respiratory failure [MP:0002066]| abnormal motor capabilities/coordination/movement [MP:0002083]| premature death [MP:0002106]| abnormal muscle physiology [MP:0002108]| abnormal muscle morphology [MP:0002109]| abnormal limb morphology [MP:0002269]| muscular atrophy [MP:0002279]| abnormal diaphragm morphology [MP:0002280]| abnormal intercostal muscle morphology [MP:0002795]| dilated cardiomyopathy [MP:0002833]| increased heart weight [MP:0002837]| dystrophic cardiac calcinosis [MP:0002841]| impaired skeletal muscle contractility [MP:0002899]| fatigue [MP:0002953]| thick ventricular wall [MP:0003061]| decreased aerobic running capacity [MP:0003084]| abnormal skeletal muscle fiber morphology [MP:0003105]| abnormal heart atrium morphology [MP:0003141]| cardiac fibrosis [MP:0003155]| abnormal telomere length [MP:0003157]| impaired muscle relaxation [MP:0003199]| calcified muscle [MP:0003358]| abnormal hypaxial muscle morphology [MP:0003393]| decreased cardiac output [MP:0003790]| absent CD4-positive [MP:0003833]| alpha beta T cells [MP:0003851]| decreased satellite cell number [MP:0003852]| skeletal muscle interstitial fibrosis [MP:0003884]| skeletal muscle necrosis [MP:0004036]| decreased macrophage cell number [MP:0004087]| abnormal muscle relaxation [MP:0004089]| abnormal muscle fiber morphology [MP:0004121]| dilated sarcoplasmic reticulum [MP:0004142]| abnormal sarcolemma morphology [MP:0004145]| abnormal muscle tone [MP:0004174]| abnormal muscle electrophysiology [MP:0004232]| abnormal spine curvature [MP:0004248]| decreased muscle weight [MP:0004262]| abnormal epaxial muscle morphology [MP:0004510]| abnormal physical strength [MP:0004564]| myositis [MP:0004566]| enlarged myocardial fiber [MP:0004597]| myocardial fiber degeneration [MP:0004703]| increased susceptibility to noise-induced hearing loss [MP:0004818]| abnormal vertebral column morphology [MP:0004819]| increased skeletal muscle mass [MP:0004973]| decreased skeletal muscle mass [MP:0005015]| increased regulatory T cell number [MP:0005017]| increased T cell number [MP:0005018]| decreased B cell number [MP:0005137]| decreased T cell number [MP:0005140]| increased growth hormone level [MP:0005165]| decreased cardiac muscle contractility [MP:0005294]| increased susceptibility to injury [MP:0005330]| abnormal heart ventricle morphology [MP:0005425]| cardiomyopathy [MP:0005608]| increased macrophage cell number [MP:0005620]| cardiac interstitial fibrosis [MP:0006085]| abnormal muscle contractility [MP:0008327]| myocardial necrosis [MP:0008416]| abnormal corticotroph morphology [MP:0008560]| increased somatotroph cell size [MP:0008566]| increased tumor necrosis factor secretion [MP:0008663]| increased interferon-gamma secretion [MP:0008687]| increased interleukin-12 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008705]| increased interleukin-4 secretion [MP:0008837]| increased interleukin-6 secretion [MP:0008838]| increased transforming growth factor level [MP:0008866]| decreased transforming growth factor level [MP:0008874]| chromosomal instability [MP:0009398]| decreased physiological sensitivity to xenobiotic [MP:0009399]| abnormal skeletal muscle fiber size [MP:0009400]| increased skeletal muscle fiber size [MP:0009401]| decreased skeletal muscle fiber size [MP:0009402]| increased skeletal muscle fiber diameter [MP:0009403]| decreased skeletal muscle fiber diameter [MP:0009404]| increased variability of skeletal muscle fiber size [MP:0009405]| centrally nucleated skeletal muscle fibers [MP:0009406]| increased skeletal muscle fiber number [MP:0009410]| decreased skeletal muscle fiber number [MP:0009412]| abnormal skeletal muscle satellite cell proliferation [MP:0009413]| skeletal muscle fiber degeneration [MP:0009414]| skeletal muscle fiber atrophy [MP:0009415]| skeletal muscle fiber necrosis [MP:0009416]| skeletal muscle degeneration [MP:0009417]| cardiac muscle degeneration [MP:0009419]| skeletal muscle atrophy [MP:0009420]| skeletal muscle fibrosis [MP:0009461]| skeletal muscle endomysial fibrosis [MP:0010024]| skeletal muscle hypertrophy [MP:0010053]| increased total body fat amount [MP:0010090]| decreased grip strength [MP:0010106]| increased circulating creatine kinase level [MP:0010226]| abnormal circulating pyruvate kinase level [MP:0010227]| increased quadriceps weight [MP:0010238]| decreased quadriceps weight [MP:0010239]| increased skeletal muscle weight [MP:0010252]| decreased skeletal muscle weight [MP:0010254]| anterior subcapsular cataracts [MP:0010581]| nuclear cataracts [MP:0010632]| abnormal atrium myocardial trabeculae morphology [MP:0011086]| cardiac muscle necrosis [MP:0011952]| postnatal lethality [MP:0011966]| incomplete penetrance [MP:0011967]| decreased cardiac stroke volume [MP:0012106]| abnormal auditory brainstem response waveform shape [MP:0013237]| increased or absent threshold for auditory brainstem response [MP:0013467]| impaired exercise endurance [MP:0014143]| abnormal skeletal muscle regeneration [MP:0020309]| diaphragmitis [MP:0030428] | Myh6|DMD||Dmd| | 041198-JAX | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:6583703 | MMRRC_41198-JAX, MMRRC_041198, MMRRC_41198 | 2026-09-19 06:40:41 | 0 | |||
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CD10.Cg-Tg(ERE-TK,lacZ)6Nagl/Mmmh Resource Report Resource Website |
RRID:MMRRC_041182-MU | Mus musculus | Research areas: Cancer, Cell Biology, Developmental Biology, Immunology and Inflammation, Metabolism, Models for Human Disease, Neurobiology, Obesity, Reproduction, Research Tools; Mutation Type: Transgenic ; Collection: | TK1|ERE|lacZ| | 041182-MU | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11606437 | MMRRC_41182-MU, MMRRC_041182, MMRRC_41182 | 2026-09-19 06:40:41 | 0 | ||||
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B6J.Cg-Tg(ERE-TK,lacZ)6Nagl/Mmmh Resource Report Resource Website |
RRID:MMRRC_041180-MU | Mus musculus | Research areas: Cancer, Cell Biology, Developmental Biology, Immunology and Inflammation, Metabolism, Models for Human Disease, Neurobiology, Obesity, Reproduction, Research Tools; Mutation Type: Transgenic ; Collection: | TK1|lacZ|ERE| | 041180-MU | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11606437 | MMRRC_41180-MU, MMRRC_041180, MMRRC_4118 | 2026-09-19 06:40:41 | 0 | ||||
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FVB/N-Tg(Ckm-Prkaa2*D157A)1Ljg/Mmjax Resource Report Resource Website |
RRID:MMRRC_041177-JAX | Mus musculus | Research areas: Diabetes, Metabolism, Obesity, Research Tools; Mutation Type: Transgenic ; Collection: | Ckm|Prkaa2| | 041177-JAX | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:16186119 PMID:19403598 PMID:20622170 PMID:20701589 PMID:18728234 PMID:17709097 PMID:17513699 PMID:17452058 PMID:17287469 PMID:16804077 PMID:15811316 |
MMRRC_41177-JAX, MMRRC_041177, MMRRC_41177 | 2026-09-19 06:40:40 | 0 | ||||
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B6C3-Tg(Myh6-PDK4)1Sakl/Mmmh Resource Report Resource Website |
RRID:MMRRC_041410-MU | Mus musculus | Research areas: Cardiovascular, Diabetes, Metabolism, Models for Human Disease; Mutation Type: Transgenic ; Collection: | Myh6|Pdk4| | 041410-MU | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:18083902 PMID:21321124 |
MMRRC_41410-MU, MMRRC_041410, MMRRC_4141 | 2026-09-19 06:40:44 | 0 | ||||
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C.Cg-Tg(Igh-LMP1)3Ratr/Mmnc Resource Report Resource Website |
RRID:MMRRC_041420-UNC | Mus musculus | Research areas: Cancer, Virology; Mutation Type: Transgenic ; Collection: | |LMP1| | 041420-UNC | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9751773 PMID:16247482 PMID:17997602 PMID:22991431 |
MMRRC_41420-UNC, MMRRC_041420, MMRRC_4142 | 2026-09-19 06:40:45 | 0 | ||||
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B6.Cg-Tg(Igh-Lmp2a)ERlon/Mmnc Resource Report Resource Website |
RRID:MMRRC_041421-UNC | Mus musculus | Research areas: Cancer, Virology; Mutation Type: Transgenic ; Collection: | |LMP2A| | 041421-UNC | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9768760 PMID:22991431 PMID:18579586 PMID:18559925 PMID:11489945 PMID:15361852 |
MMRRC_41421-UNC, MMRRC_041421, MMRRC_41421 | 2026-09-19 06:40:45 | 0 | ||||
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STOCK Tg(Adora2a-cre)KG139Gsat/Mmucd Resource Report Resource Website 10+ mentions |
RRID:MMRRC_031168-UCD | Mus musculus | Research areas: Cell Biology, Developmental Biology, Neurobiology, Research Tools; Mutation Type: Transgenic ; Collection: GENSAT | |Adora2a|cre | 031168-UCD | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:14586460 | MMRRC_31168-UCD, MMRRC_031168, MMRRC_31168 | 2026-09-19 06:38:27 | 33 |
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