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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
https://www.jax.org/strain/010565
Source Database: JAX Mice and Services
Affected Genes: beta-2 microglobulin|beta-2-microglobulin|transgene insertion 3; David V Serreze|histocompatibility 2; D region|major histocompatibility complex; class I; A
Genomic Alteration: targeted mutation 1; University of North Carolina|transgene insertion 3; David V Serreze
Availability: sperm
Synonyms: NOD.A24/HHD
Notes: gene symbol note: beta-2 microglobulin|beta-2-microglobulin|transgene insertion 3; David V Serreze|histocompatibility 2; D region|major histocompatibility complex; class I; A; congenic strain: B2m|B2M|Tg(HLA-A24/H2-D/B2M)3Dvs|H2-D|HLA-A
Proper citation: RRID:IMSR_JAX:010565 Copy
Issue
https://www.jax.org/strain/006022
Source Database: JAX Mice and Services
Affected Genes: CD2 molecule|CD4 molecule|transgene insertion 1; John F Elliott|histocompatibility 2; class II antigen A; beta 1|recombination activating 1|major histocompatibility complex; class II; DQ beta 1|major histocompatibility complex; class II; DQ alpha 1
Genomic Alteration: transgene insertion 1; John F Elliott|targeted mutation 1; Michael J Grusby|targeted mutation 1; Peter Mombaerts
Availability: embryo
Synonyms: NOD.Cg-Rag1
Notes: gene symbol note: CD2 molecule|CD4 molecule|transgene insertion 1; John F Elliott|histocompatibility 2; class II antigen A; beta 1|recombination activating 1|major histocompatibility complex; class II; DQ beta 1|major histocompatibility complex; class II; DQ alpha 1; mutant strain|congenic strain: CD2|CD4|Tg(CD2-CD4;HLA-DQA1;HLA-DQB1)1Ell|H2-Ab1|Rag1|HLA-DQB1|HLA-DQA1
Proper citation: RRID:IMSR_JAX:006022 Copy
Issue
https://www.jax.org/strain/006024
Source Database: JAX Mice and Services
Affected Genes: major histocompatibility complex; class II; DQ beta 1|major histocompatibility complex; class II; DQ alpha 1|transgene insertion N8; John F Elliott|histocompatibility 2; class II antigen A; beta 1|CD4 molecule|recombination activating 1
Genomic Alteration: transgene insertion N8; John F Elliott|targeted mutation 1; Michael J Grusby|targeted mutation 1; Peter Mombaerts
Availability: embryo
Synonyms: NOD.Cg-Rag1
Notes: gene symbol note: major histocompatibility complex; class II; DQ beta 1|major histocompatibility complex; class II; DQ alpha 1|transgene insertion N8; John F Elliott|histocompatibility 2; class II antigen A; beta 1|CD4 molecule|recombination activating 1; mutant strain|congenic strain: HLA-DQB1|HLA-DQA1|Tg(CD4;HLA-DQA1;HLA-DQB1)N8Ell|H2-Ab1|CD4|Rag1
Proper citation: RRID:IMSR_JAX:006024 Copy
Issue
https://www.jax.org/strain/006345
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 4; Christopher C Goodnow|Immunoglobulin heavy chain (gamma polypeptide)
Genomic Alteration: transgene insertion 4; Christopher C Goodnow
Availability: embryo
Synonyms: NOD.IgHEL
Notes: gene symbol note: transgene insertion 4; Christopher C Goodnow|Immunoglobulin heavy chain (gamma polypeptide); mutant strain|congenic strain: Tg(IghelMD4)4Ccg|Ighg
Proper citation: RRID:IMSR_JAX:006345 Copy
Issue Issue
https://www.jax.org/strain/006608
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 4; Christopher C Goodnow|immunoglobulin heavy constant mu|Immunoglobulin heavy chain (gamma polypeptide)
Genomic Alteration: transgene insertion 4; Christopher C Goodnow|targeted mutation 1; University of Cologne
Availability: embryo
Synonyms: NOD.IgHEL.IgH-/-. NOD.Cg-Igh-6
Notes: gene symbol note: transgene insertion 4; Christopher C Goodnow|immunoglobulin heavy constant mu|Immunoglobulin heavy chain (gamma polypeptide); mutant strain|congenic strain: Tg(IghelMD4)4Ccg|Ighm|Ighg
Proper citation: RRID:IMSR_JAX:006608 Copy
Issue
https://www.jax.org/strain/006825
Source Database: JAX Mice and Services
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: embryo
Notes: gene symbol note: Fas cell surface death receptor; coisogenic strain|mutant strain: Fas
Proper citation: RRID:IMSR_JAX:006825 Copy
Issue
https://www.jax.org/strain/007082
Source Database: JAX Mice and Services
Affected Genes: tumor necrosis factor
Genomic Alteration: targeted mutation 1; George Kollias
Availability: sperm
Notes: gene symbol note: tumor necrosis factor; congenic strain: Tnf
Proper citation: RRID:IMSR_JAX:007082 Copy
Issue Issue
https://www.jax.org/strain/007078
Source Database: JAX Mice and Services
Affected Genes: interleukin 6
Genomic Alteration: targeted mutation 1; Manfred Kopf
Availability: sperm
Notes: gene symbol note: interleukin 6; congenic strain: Il6
Proper citation: RRID:IMSR_JAX:007078 Copy
Issue
https://www.jax.org/strain/007069
Source Database: JAX Mice and Services
Affected Genes: apolipoprotein E
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: sperm
Synonyms: AKR.129P2(B6)-Apoe
Notes: gene symbol note: apolipoprotein E; mutant stock: Apoe
Proper citation: RRID:IMSR_JAX:007069 Copy
Issue
https://www.jax.org/strain/030896
Source Database: JAX Mice and Services
Affected Genes: C-C motif chemokine receptor 2|C-C motif chemokine receptor 5|apolipoprotein E
Genomic Alteration: targeted mutation 1.1; Bruno Luckow|targeted mutation 3.1; Bruno Luckow|targeted mutation 1; University of North Carolina
Availability: embryo
Notes: gene symbol note: C-C motif chemokine receptor 2|C-C motif chemokine receptor 5|apolipoprotein E; mutant strain|congenic strain: Ccr2|Ccr5|Apoe
Proper citation: RRID:IMSR_JAX:030896 Copy
Issue
https://www.jax.org/strain/030892
Source Database: JAX Mice and Services
Affected Genes: C-C motif chemokine receptor 1|apolipoprotein E
Genomic Alteration: targeted mutation 1; Ji-Liang Gao|targeted mutation 1; University of North Carolina
Availability: sperm
Notes: gene symbol note: C-C motif chemokine receptor 1|apolipoprotein E; mutant strain|congenic strain: Ccr1|Apoe
Proper citation: RRID:IMSR_JAX:030892 Copy
Issue
https://www.jax.org/strain/030893
Source Database: JAX Mice and Services
Affected Genes: C-C motif chemokine receptor 2|apolipoprotein E
Genomic Alteration: targeted mutation 1.1; Bruno Luckow|targeted mutation 1; University of North Carolina
Availability: sperm
Notes: gene symbol note: C-C motif chemokine receptor 2|apolipoprotein E; mutant strain|congenic strain: Ccr2|Apoe
Proper citation: RRID:IMSR_JAX:030893 Copy
Issue
https://www.jax.org/strain/032429
Source Database: JAX Mice and Services
Affected Genes: pancreatic and duodenal homeobox 1|Cre recombinase and estrogen receptor 1 fusion gene|transformation related protein 53|Kras proto-oncogene; GTPase|transgene insertion; Douglas A Melton
Genomic Alteration: transgene insertion; Douglas A Melton|targeted mutation 1; Anton Berns|targeted mutation 4; Tyler Jacks
Availability: live
Notes: gene symbol note: pancreatic and duodenal homeobox 1|Cre recombinase and estrogen receptor 1 fusion gene|transformation related protein 53|Kras proto-oncogene; GTPase|transgene insertion; Douglas A Melton; mutant stock: Pdx1|cre/Esr1|Trp53|Kras|Tg(Pdx1-cre/Esr1*)#Dam
Proper citation: RRID:IMSR_JAX:032429 Copy
Issue
https://www.jax.org/strain/033761
Source Database: JAX Mice and Services
Affected Genes: NK3 homeobox 1|phosphatase and tensin homolog||gene trap ROSA 26; Philippe Soriano|Kras proto-oncogene; GTPase
Genomic Alteration: targeted mutation 4; Michael M Shen|targeted mutation 1; Hong Wu|targeted mutation 3; Hongkui Zeng|targeted mutation 4; Tyler Jacks
Availability: live
Notes: gene symbol note: NK3 homeobox 1|phosphatase and tensin homolog||gene trap ROSA 26; Philippe Soriano|Kras proto-oncogene; GTPase; mutant stock: Nkx3-1|Pten||Gt(ROSA)26Sor|Kras
Proper citation: RRID:IMSR_JAX:033761 Copy
Issue
https://www.jax.org/strain/033910
Source Database: JAX Mice and Services
Affected Genes: insulin I|insulin II
Genomic Alteration: targeted mutation 1; Jacques Jami|targeted mutation 1; Massimo Trucco
Availability: sperm
Notes: gene symbol note: insulin I|insulin II; mutant strain|congenic strain: Ins1|Ins2
Proper citation: RRID:IMSR_JAX:033910 Copy
Issue
https://www.taconic.com/knockout-mouse/csmd1-targeted
Source Database: Taconic Biosciences
Affected Genes: CUB and Sushi multiple domains 1
Genomic Alteration: targeted mutation 1; Lexicon Genetics
Availability: archived
Notes: gene symbol note: CUB and Sushi multiple domains 1; mutant strain: Csmd1
Proper citation: RRID:IMSR_TAC:TF0137 Copy
Issue Issue
http://www.taconic.com/mouse-model/ciea-brg-mouse
Source Database: Taconic Biosciences
Affected Genes: recombination activating gene 2|interleukin 2 receptor; gamma chain
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Kazuo Sugamura
Availability: live
Synonyms: BRG
Notes: gene symbol note: recombination activating gene 2|interleukin 2 receptor; gamma chain; mutant strain|congenic strain: Rag2|Il2rg
Proper citation: RRID:IMSR_TAC:11503 Copy
Issue Issue
https://www.taconic.com/mouse-model/tk-nog
Source Database: Taconic Biosciences
Affected Genes: interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide
Genomic Alteration: targeted mutation 1; Kazuo Sugamura|severe combined immunodeficiency
Availability: live
Notes: gene symbol note: interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide; mutant strain|congenic strain: Il2rg|Prkdc
Proper citation: RRID:IMSR_TAC:12907 Copy
Issue Issue
http://www.taconic.com/mouse-model/hgm-csfhil3-nog
Source Database: Taconic Biosciences
Affected Genes: interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide
Genomic Alteration: targeted mutation 1; Kazuo Sugamura|severe combined immunodeficiency
Availability: live
Notes: gene symbol note: interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide; mutant strain|congenic strain: Il2rg|Prkdc
Proper citation: RRID:IMSR_TAC:13395 Copy
Issue
http://www.taconic.com/transgenic-mouse-model/abbb2m
Source Database: Taconic Biosciences
Affected Genes: beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: targeted mutation 1; Rudolf Jaenisch|targeted mutation 1; Michael J Grusby
Availability: archived
Synonyms: B6.129S2-H2-Ab1
Notes: gene symbol note: beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1; mutant strain|congenic strain: B2m|H2-Ab1
Proper citation: RRID:IMSR_TAC:4080 Copy
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