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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00023585
Source Database: WormBase (WB)
Affected Genes: WBGene00003917(par-2)
Genomic Alteration: WBGene00003917(par-2)
Availability: available
Source References: PMID:37729912, PMID:39652540
Synonyms: par-2(it315[mCherry::par-2]) III.
Alternate IDs: WB-STRAIN:KK1254, CGC_KK1254
Notes: par-2(it315) exhibits a weak maternal effect sterility, suggesting that the tag reduces the protein activity. Note, however, that double homozygous mutants of it315 with pkc-3(it309) or par-6(it310) exhibited partially penetrant and variable maternal effect lethality and maternal effect sterility that was stronger than it315 alone. Thus, although the GFP tags on pkc-3 and par-6 show no effect in an otherwise wild-type background, they do seem to somewhat compromise the activity of the proteins they tag. Made in N2 background.|"Supplementary_genotype par-2(it315[mCherry::par-2]) III"
Proper citation: RRID:WB-STRAIN:WBStrain00023585 Copy
http://www.wormbase.org/db/get?name=WBStrain00023586
Source Database: WormBase (WB)
Affected Genes: WBGene00003916(par-1)
Genomic Alteration: WBGene00003916(par-1)
Availability: available
Source References: PMID:33300872, PMID:39652540
Synonyms: par-1(it324[par-1::GFP::par-1 exon11a]) V.
Alternate IDs: WB-STRAIN:KK1262, CGC_KK1262
Notes: Superficially wild-type. Made in N2 background.|"WBStrain provided so WBPaper00060754 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00023586 Copy
http://www.wormbase.org/db/get?name=WBStrain00023527
Source Database: WormBase (WB)
Affected Genes: WBGene00006527(tax-6)
Genomic Alteration: WBGene00006527(tax-6)
Availability: available
Synonyms: tax-6(jh107) IV.
Alternate IDs: WB-STRAIN:KJ306, CGC_KJ306
Notes: Gain-of-function mutant. Hypersensitive to serotonin.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00023527 Copy
http://www.wormbase.org/db/get?name=WBStrain00023525
Source Database: WormBase (WB)
Affected Genes: WBGene00000802(crt-1)
Genomic Alteration: WBGene00000802(crt-1)
Availability: available
Source References: PMID:39519157
Synonyms: crt-1(jh101) V.
Alternate IDs: WB-STRAIN:KJ216, CGC_KJ216
Notes: Mutagen:UV/TMP
Proper citation: RRID:WB-STRAIN:WBStrain00023525 Copy
http://www.wormbase.org/db/get?name=WBStrain00023529
Source Database: WormBase (WB)
Affected Genes: WBGene00015062(trx-1)
Genomic Alteration: WBGene00015062(trx-1)
Availability: available
Source References: PMID:38446031
Synonyms: trx-1(jh127) II.
Alternate IDs: WB-STRAIN:KJ412, CGC_KJ412
Notes: Made_by Changhoon Ji|"Made_by: Changhoon Ji"|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00023529 Copy
http://www.wormbase.org/db/get?name=WBStrain00023603
Source Database: WormBase (WB)
Availability: available
Synonyms: huIs7.
Alternate IDs: WB-STRAIN:KN53, CGC_KN53
Notes: huIs7 [hsp-16.2p::Myc::bar-1(delta N) + mec-7p::GFP + dpy-20(+)]. Muv. Posterior migration of the QR descendants. Reference: de Groot et al. (2014) Science Signal. Ra26.
Proper citation: RRID:WB-STRAIN:WBStrain00023603 Copy
http://www.wormbase.org/db/get?name=WBStrain00023604
Source Database: WormBase (WB)
Affected Genes: WBGene00004932(sod-3)
Genomic Alteration: WBGene00004932(sod-3)
Availability: available
Source References: PMID:38403745
Synonyms: huIs33.
Alternate IDs: WB-STRAIN:KN259, CGC_KN259
Notes: huIs33 [sod-3::GFP + rol-6(su1006)]. Pick Rollers to maintain.
Proper citation: RRID:WB-STRAIN:WBStrain00023604 Copy
http://www.wormbase.org/db/get?name=WBStrain00023638
Source Database: WormBase (WB)
Availability: available
Synonyms: nuIs190 X.
Alternate IDs: WB-STRAIN:KP3957, CGC_KP3957
Notes: Made_by: D Sieburth & Q Ch'ng|"nuIs190 [unc-129p::ins-22::Venus + myo-2p::NLS::GFP] X. Pick GFP+ to maintain. Not all animals express GFP. Array might be prone to silencing or not homozygous. [NOTE: nuIs190 was previously described as carrying myo-2p::GFP without an NLS.] Reference: Ch'ng Q, Sieburth D, Kaplan JM. PLoS Genet. 2008 Nov;4(11):e1000283."
Proper citation: RRID:WB-STRAIN:WBStrain00023638 Copy
http://www.wormbase.org/db/get?name=WBStrain00023630
Source Database: WormBase (WB)
Affected Genes: WBGene00001189(egl-21)
Genomic Alteration: WBGene00001189(egl-21)
Availability: available
Source References: PMID:34506477, PMID:36653384, PMID:38573858
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:KP2018, CGC_KP2018
Notes: Mutation confirmed by Nonet lab.
Proper citation: RRID:WB-STRAIN:WBStrain00023630 Copy
http://www.wormbase.org/db/get?name=WBStrain00023627
Source Database: WormBase (WB)
Affected Genes: WBGene00000068(acy-1)
Genomic Alteration: WBGene00000068(acy-1)
Availability: available
Source References: PMID:9526004
Synonyms: acy-1(nu329) III.
Alternate IDs: WB-STRAIN:KP1182, CGC_KP1182
Notes: Made_by: Allison Berger|"No obvious phenotype on its own. Suppresses cell swelling and death caused by expression of a GTPase defective Gxs subunit expressed from the glr-1 promoter, semi-dominant. Strongest allele."
Proper citation: RRID:WB-STRAIN:WBStrain00023627 Copy
http://www.wormbase.org/db/get?name=WBStrain00023656
Source Database: WormBase (WB)
Affected Genes: WBGene00004789(sgk-1)
Genomic Alteration: WBGene00004789(sgk-1)
Availability: available
Synonyms: sgk-1(ft15) X.
Alternate IDs: WB-STRAIN:KQ1564, CGC_KQ1564
Notes: ft15 allele is a gain-of-function mutation in sgk-1. sgk-1(ft15) mutants have normal body size and normalize the small body size of rict-1 loss-of-function mutants. Reference: Jones KT, et al. PLos Biol. 2009 Mar 3;7(3):e60. doi: 10.1371/journal.pbio.1000060. PMID: 19260765.
Proper citation: RRID:WB-STRAIN:WBStrain00023656 Copy
http://www.wormbase.org/db/get?name=WBStrain00023654
Source Database: WormBase (WB)
Affected Genes: WBGene00000103(akt-2)|WBGene00004789(sgk-1)
Genomic Alteration: WBGene00000103(akt-2), WBGene00004789(sgk-1)
Availability: available
Synonyms: akt-2(tm812) sgk-1(ft15) X.
Alternate IDs: WB-STRAIN:KQ1323, CGC_KQ1323
Notes: ft15 allele is a gain-of-function mutation in sgk-1. sgk-1(ft15) mutants have normal body size and normalize the small body size of rict-1 loss-of-function mutants. Reference: Jones KT, et al. PLos Biol. 2009 Mar 3;7(3):e60. doi: 10.1371/journal.pbio.1000060. PMID: 19260765.
Proper citation: RRID:WB-STRAIN:WBStrain00023654 Copy
http://www.wormbase.org/db/get?name=WBStrain00023647
Source Database: WormBase (WB)
Affected Genes: WBGene00009245(rict-1)
Genomic Alteration: WBGene00009245(rict-1)
Availability: available
Synonyms: rict-1(mg360) II.
Alternate IDs: WB-STRAIN:KQ6, CGC_KQ6
Notes: Small, slightly developmentally delayed. Increased Nile Red staining.
Proper citation: RRID:WB-STRAIN:WBStrain00023647 Copy
http://www.wormbase.org/db/get?name=WBStrain00023971
Source Database: WormBase (WB)
Affected Genes: WBGene00003160(mdf-1)|WBGene00006782(unc-46)
Genomic Alteration: WBGene00003160(mdf-1), WBGene00006782(unc-46)
Availability: available
Source References: PMID:10587648
Synonyms: unc-46(e177) mdf-1(gk2) V/nT1 [let-?(m435)] (IV;V).
Alternate IDs: WB-STRAIN:KR3627, CGC_KR3627
Notes: C50F4.11. Strain segregates WT, Uncs (give Sterile progeny or progeny with reduced brood size, all of which arrest before hatching (24%), at various stages of larval development (55%), or later) and dead eggs. Rec'd new stock 11/2002. Attribution: Paper_evidence WBPaper00005604|"Made_by: Elaine Lau"
Proper citation: RRID:WB-STRAIN:WBStrain00023971 Copy
http://www.wormbase.org/db/get?name=WBStrain00024047
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00000410(cdk-9)
Genomic Alteration: WBGene00000254(bli-4), WBGene00000410(cdk-9)
Availability: available
Synonyms: cdk-9(tm2884) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:KW2090, CGC_KW2090
Notes: Segregates WT green-glowing heterozygotes and non-glowing cdk-9 homozygotes (arrest as L1-L2 larvae). qIs48 is an insertion of ccEx9747 (carries myo-2::GFP, pes-10::GFP, and a gut enhancer fused to GFP) onto the hT2 chromosome and is homozygous lethal. Reference: Bowman EA, et al. Development. (In Press).
Proper citation: RRID:WB-STRAIN:WBStrain00024047 Copy
http://www.wormbase.org/db/get?name=WBStrain00024040
Source Database: WormBase (WB)
Affected Genes: WBGene00004055(pmk-1)
Genomic Alteration: WBGene00004055(pmk-1)
Availability: available
Source References: PMID:31576668, PMID:31735670, PMID:31823826, PMID:32289254, PMID:31771413, PMID:32978396, PMID:33666644, PMID:34038721, PMID:37122724, PMID:37507441, PMID:37527037, PMID:37704756, PMID:37310929, PMID:37892557, PMID:37906605, PMID:38232128, PMID:38446031, PMID:38573858, PMID:38569037, PMID:38799567, PMID:38754743, PMID:39164296, PMID:39235964, PMID:39532199
Synonyms: pmk-1(km25) IV.
Alternate IDs: WB-STRAIN:KU25, CGC_KU25
Notes: Mutagen:UV/TMP|"outcrossed six times by the Matsumoto lab."|"Reference WBPaper00058956 added based on published strain data identified by Textpresso literature search."|"Sensitive to heavy metal and oxidative stress."|"Supplementary_genotype pmk-1 (km25)"|"Supplementary_genotype pmk-1(km25)"|"Supplementary_genotype [pmk-1(km25) IV.]"|"WBStrain mapped, WBPaper00059543 added based on AFP_Strain data."|"WBStrain mapped, WBPaper00061439 added based on AFP_Strain data."|"WBStrain provided so WBPaper00061436 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00024040 Copy
http://www.wormbase.org/db/get?name=WBStrain00024035
Source Database: WormBase (WB)
Affected Genes: WBGene00004758(sek-1)
Genomic Alteration: WBGene00004758(sek-1)
Availability: available
Source References: PMID:32978396, PMID:33666644, PMID:34038721, PMID:36653384, PMID:37122724, PMID:37527037, PMID:37310929, PMID:38573858, PMID:38569037
Synonyms: sek-1(km4) X.
Alternate IDs: WB-STRAIN:KU4, CGC_KU4
Notes: Egl. 2.1 kb deletion.|"Made_by: Miho Tanaka-Hino"|"WBStrain mapped, WBPaper00061439 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00024035 Copy
http://www.wormbase.org/db/get?name=WBStrain00024039
Source Database: WormBase (WB)
Affected Genes: WBGene00002187(kgb-1)
Genomic Alteration: WBGene00002187(kgb-1)
Availability: available
Source References: PMID:37704756
Synonyms: kgb-1(km21) IV.
Alternate IDs: WB-STRAIN:KU21, CGC_KU21
Notes: Mutagen:UV/TMP|"Sensitive to heavy metal stress."|"Supplementary_genotype [kgb-1(km21) IV.]"
Proper citation: RRID:WB-STRAIN:WBStrain00024039 Copy
http://www.wormbase.org/db/get?name=WBStrain00024075
Source Database: WormBase (WB)
Affected Genes: WBGene00004010(pha-1)
Genomic Alteration: WBGene00004010(pha-1)
Availability: available
Synonyms: pha-1(e2123) III; rnyEx133.
Alternate IDs: WB-STRAIN:KWN246, CGC_KWN246
Notes: rnyEx133 [opt-2p:::opt-2(aa1-412)::GFP) + pha-1(+)]. Maintain at 25C to select for animal carrying the array. Labels apical intestinal membrane. Reference: Nehrke (2003) 278(45):44657-66.
Proper citation: RRID:WB-STRAIN:WBStrain00024075 Copy
http://www.wormbase.org/db/get?name=WBStrain00024074
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00004010(pha-1)
Genomic Alteration: WBGene00001864(him-5), WBGene00004010(pha-1)
Availability: available
Source References: PMID:34467850
Synonyms: pha-1(e2123) III; him-5(e1490) V; rnyEx109.
Alternate IDs: WB-STRAIN:KWN190, CGC_KWN190
Notes: rnyEx109 [nhx-2p::D3cpv + pha-1(+)]. Maintain at 20-25C to select for array. KWN190 strain expresses the FRET-based calcium indicator protein D3cpv throughout the cytoplasm of intestinal cells. Dual emission ratio imaging (ex. 435, em. 480/535-nm) can be used to measure intestinal calcium and, although the FRET pair is CFP/YFP, intestinal D3cpv fluorescence is observable under standard GFP filter sets. The D3cpv biosensor has the advantages of being relatively pH-insensitive and not interfering with endogenous calmodulin signaling. References: Am J Physiol Cell Physiol. 301:C1389-1403. Am J Physiol Cell Physiol. 297:C1071-81. FASEB J. 27:760-768. PLoS Biol. 11: e1001613.|"WBStrain provided so WBPaper00061870 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00024074 Copy
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