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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00006957
Source Database: WormBase (WB)
Affected Genes: WBGene00001867(him-8)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00001867(him-8), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: oxTi302 I; oxTi75 II; oxTi411 unc-119(ed3) III; him-8(e1489) IV.
Alternate IDs: WB-STRAIN:EG8040, CGC_EG8040
Notes: Made_by: Matthew LaBella|"oxTi302 [eft-3p::mCherry::tbb-2 3'UTR + Cbr-unc-119(+)]; inserted in Chr. I: 10,166,145. oxTi75 [eft-3p::GFP::H2B::tbb-2 3'UTR + unc-18(+)] II; inserted in Chr. II: 5,448,544. oxTi411 [eft-3p::tdTomato::H2B::unc-54 3'UTR + Cbr-unc-119(+)] inserted in Chr. III: 6,076,837. Him. Somewhat sick at higher temperatures. Maintain at 20C or below. This mapping strain uses three dominant fluorescent insertions that can be distinguished when scoring segregation. Please see www.wormbuilder.org for additional strain information."
Proper citation: RRID:WB-STRAIN:WBStrain00006957 Copy
http://www.wormbase.org/db/get?name=WBStrain00006965
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:32275886, PMID:39358459
Synonyms: unc-119(ed3) III; oxTi365 V.
Alternate IDs: WB-STRAIN:EG8082, CGC_EG8082
Notes: oxTi365 [ttTi5605 + NeoR(+) + unc-18(+)]. Unc. Grows best at 20C on HB101. Strain contains a universal MosSCI insertion site that is compatible with targeting vectors for the ttTi5605 site (for example, pCFJ150 derivatives). This site is generally permissive for germline expression. Transgenic animals are NeoR and carry an extra copy of unc-18(+). Please see www.wormbuilder.org for more details.|"WBStrain mapped, WBPaper00059536 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00006965 Copy
http://www.wormbase.org/db/get?name=WBStrain00006963
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:32275886
Synonyms: oxTi444 unc-119(ed3) III.
Alternate IDs: WB-STRAIN:EG8080, CGC_EG8080
Notes: oxTi444 [ttTi5605 + NeoR(+) + unc-18(+)]. Unc. Grows best at 20C on HB101. Strain contains a universal MosSCI insertion site that is compatible with targeting vectors for the ttTi5605 site (for example, pCFJ150 derivatives). This site is generally permissive for germline expression. Transgenic animals are NeoR and carry an extra copy of unc-18(+). Please see www.wormbuilder.org for more details.|"WBStrain mapped, WBPaper00059536 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00006963 Copy
http://www.wormbase.org/db/get?name=WBStrain00006962
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:32275886, PMID:32687264, PMID:37665665
Synonyms: oxTi179 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:EG8079, CGC_EG8079
Notes: oxTi179 [ttTi5605 + NeoR(+) + unc-18(+)]. Unc. Grows best at 20C on HB101. Strain contains a universal MosSCI insertion site that is compatible with targeting vectors for the ttTi5605 site (for example, pCFJ150 derivatives). This site is generally permissive for germline expression. Transgenic animals are NeoR and carry an extra copy of unc-18(+). Please see www.wormbuilder.org for more details.|"Supplementary_genotype oxTi179 II; unc-119(ed3) III"|"WBStrain mapped, WBPaper00059536 added based on AFP_Strain data."|"WBStrain mapped, WBPaper00059997 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00006962 Copy
http://www.wormbase.org/db/get?name=WBStrain00006908
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; oxTi553 V.
Alternate IDs: WB-STRAIN:EG7944, CGC_EG7944
Notes: oxTi553 [eft-3p::tdTomato::H2B::unc-54 3'UTR + Cbr-unc-119(+)]. Maintain at 20C; somewhat sick at 25C. Broad, nuclear red fluorescence. pCFJ453 inserted into unc-119(ed3) III (11X outcross) background. Please see www.wormbuilder.org for exact insertion site.
Proper citation: RRID:WB-STRAIN:WBStrain00006908 Copy
http://www.wormbase.org/db/get?name=WBStrain00007175
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00003111(mab-20)
Genomic Alteration: WBGene00001864(him-5), WBGene00003111(mab-20)
Availability: available
Source References: PMID:1782863
Synonyms: mab-20(bx61) I; him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM253, CGC_EM253
Notes: Ray 3 and 4 fusion >60% at non-permissive temp. Ray 1 and 2 fusion about 10% at non-permissive temp. ts period is around L3-L4.
Proper citation: RRID:WB-STRAIN:WBStrain00007175 Copy
http://www.wormbase.org/db/get?name=WBStrain00007174
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00006543(tbx-2)
Genomic Alteration: WBGene00001864(him-5), WBGene00006543(tbx-2)
Availability: available
Source References: EMPTY
Synonyms: tbx-2(bx59) III; him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM207, CGC_EM207
Notes: Conditional lethal: inviable when grown at 25C. Wild type at 16C. Viable when grown at 20C; partial ray loss at 20C. Shifting males during ray assembly to non-permissive temperature results in ray loss. No lineage defect.
Proper citation: RRID:WB-STRAIN:WBStrain00007174 Copy
http://www.wormbase.org/db/get?name=WBStrain00007105
Source Database: WormBase (WB)
Affected Genes: WBGene00003230(mex-5)|WBGene00004027(pie-1)
Genomic Alteration: WBGene00003230(mex-5), WBGene00004027(pie-1)
Availability: available
Source References: EMPTY
Synonyms: pie-1(ne4301[pie-1::gfp]) III; mex-5(egx1[F294N & F339N]) IV.
Alternate IDs: WB-STRAIN:EGD175, CGC_EGD175
Notes: pie-1(ne4301) inserted GFP into pie-1 locus tagging endogenous pie-1 with GFP. mex-5(egx1[F294N, F339N]) modifies the endogenous mex-5 locus to disrupt zinc finger motifs. Reference: Han et al, Current Biology 2017.|"pie-1(ne4301) inserted GFP to pie-1 locus tagging endogenous pie-1 with GFP. mex-5(egx1[F294N, F339N]) modifies the endogenous mex-5 locus to disrupt zinc finger motifs. Reference: Han et al, Current Biology 2017."
Proper citation: RRID:WB-STRAIN:WBStrain00007105 Copy
http://www.wormbase.org/db/get?name=WBStrain00007104
Source Database: WormBase (WB)
Affected Genes: WBGene00006752(unc-13)
Genomic Alteration: WBGene00006752(unc-13)
Availability: available
Source References: PMID:36653384
Synonyms: unc-13(s69) I.
Alternate IDs: WB-STRAIN:EG9631, CGC_EG9631
Notes: Aldicarb resistant. This allele is a small exonic deletion that frameshifts exon 21, thus deleting the MUN domain of both long and short isoforms of unc-13. The reference allele e51 is R471-stop, affecting only UNC-13L. Derived by 2x outcross of BC168. Reference: Rose AM & Baillie DL. Genetics. 1980 Nov;96(3):639-48.|"Mutagen: Formaldehyde"
Proper citation: RRID:WB-STRAIN:WBStrain00007104 Copy
http://www.wormbase.org/db/get?name=WBStrain00007125
Source Database: WormBase (WB)
Affected Genes: WBGene00003030(lin-45)
Genomic Alteration: WBGene00003030(lin-45)
Availability: available
Source References: PMID:37643243
Synonyms: lin-45(dx19) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EJ521, CGC_EJ521
Notes: Heterozygotes are Unc and segregate Unc, non-Unc Steriles, larval lethals and dead eggs. dx19 is a strong lin-45 raf allele: dx19 homozygotes from dx19/+ heterozygous parents are 13% larval lethal and among the adults, 100% are Sterile and Vul.|"Supplementary_genotype lin-45(dx19)/nT1 [unc(n754) let] (IV;V)"
Proper citation: RRID:WB-STRAIN:WBStrain00007125 Copy
http://www.wormbase.org/db/get?name=WBStrain00007119
Source Database: WormBase (WB)
Affected Genes: WBGene00001651(gon-2)
Genomic Alteration: WBGene00001651(gon-2)
Availability: available
Source References: PMID:37624117, PMID:37729202, PMID:38446031
Synonyms: gon-2(q362) I.
Alternate IDs: WB-STRAIN:EJ26, CGC_EJ26
Notes: Starvation sensitive gonadogenesis defect.|"Supplementary_genotype gon-2(q362) I."|"WBStrain provided so WBPaper00061436 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00007119 Copy
http://www.wormbase.org/db/get?name=WBStrain00007251
Source Database: WormBase (WB)
Affected Genes: WBGene00004804(skn-1)
Genomic Alteration: WBGene00004804(skn-1)
Availability: available
Source References: PMID:32302543, PMID:33851304, PMID:36653384, PMID:37606250, PMID:38754743
Synonyms: skn-1(zu135) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EU31, CGC_EU31
Notes: Heterozygotes are Unc and segregate Unc, WT which give only dead eggs, and dead eggs. Maintain by picking Unc.|"Made_by: P Martin/B Bowerman"|"WBStrain mapped, WBPaper00059578 added based on AFP_Strain data."|"WBStrain provided so WBPaper00059477 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061925 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00007251 Copy
http://www.wormbase.org/db/get?name=WBStrain00007249
Source Database: WormBase (WB)
Affected Genes: WBGene00004804(skn-1)
Genomic Alteration: WBGene00004804(skn-1)
Availability: available
Source References: PMID:1547503, PMID:31432005, PMID:31510078, PMID:33602504, PMID:33654835, PMID:37122724, PMID:37726773, PMID:38632209, PMID:39273603
Synonyms: skn-1(zu67) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EU1, CGC_EU1
Notes: Heterozygotes are Unc and segregate Unc, WT which give only dead eggs, and dead eggs. Maintain by picking Unc.|"Reference WBPaper00057259 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058621 added based on published strain data identified by Textpresso literature search."|"Supplementary_genotype [skn-1(zu67) IV/nT1(IV;V)]"|"WBStrain mapped, WBPaper00061072 added based on AFP_Strain data."|"WBStrain mapped, WBPaper00061110 added based on AFP_Strain data."|"WBStrain provided so WBPaper00059477 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00007249 Copy
http://www.wormbase.org/db/get?name=WBStrain00007263
Source Database: WormBase (WB)
Affected Genes: WBGene00001068(dpy-6)|WBGene00003056(lon-2)|WBGene00003394(mom-1)
Genomic Alteration: WBGene00001068(dpy-6), WBGene00003056(lon-2), WBGene00003394(mom-1)
Availability: available
Source References: EMPTY
Synonyms: +/szT1 [lon-2(e678)] I; mom-1(or10) dpy-6(e14)/szT1 X.
Alternate IDs: WB-STRAIN:EU308, CGC_EU308
Notes: Heterozygotes are WT and segregate WT, Lon males, lots of dead eggs, and Dpys. The Dpys should give all dead embryos at all temperatures. Approximately 60% of these dead embryos make excess mesoderm at the expense of endoderm, due to an E to MS fate transformation. Embryonic lethality is 100% penetrant for or10.
Proper citation: RRID:WB-STRAIN:WBStrain00007263 Copy
http://www.wormbase.org/db/get?name=WBStrain00007261
Source Database: WormBase (WB)
Affected Genes: WBGene00000168(apx-1)
Genomic Alteration: WBGene00000168(apx-1)
Availability: available
Source References: EMPTY
Synonyms: apx-1(or22) V/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EU176, CGC_EU176
Notes: Heterozygotes are Unc and segregate Unc and wild type animals which give only dead progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00007261 Copy
http://www.wormbase.org/db/get?name=WBStrain00007270
Source Database: WormBase (WB)
Affected Genes: WBGene00001073(dpy-11)|WBGene00003395(mom-2)
Genomic Alteration: WBGene00001073(dpy-11), WBGene00003395(mom-2)
Availability: available
Source References: PMID:9288749, PMID:33319173
Synonyms: dpy-11(e1180) mom-2(or42) V/nT1 [let-?(m435)] (IV;V).
Alternate IDs: WB-STRAIN:EU384, CGC_EU384
Notes: Generated from papers flagged positive during the last month for data type afp_strain/other_strain.|"Heterozygotes are WT and segregate WT, Dpys and dead eggs. Dpys segregate only embryonic lethals which lack endoderm and make excess mesoderm with E adopting and MS-like fate. or42 is a recessive maternal-effect lethal."
Proper citation: RRID:WB-STRAIN:WBStrain00007270 Copy
http://www.wormbase.org/db/get?name=WBStrain00007216
Source Database: WormBase (WB)
Affected Genes: WBGene00020649(sma-10)
Genomic Alteration: WBGene00020649(sma-10)
Availability: available
Source References: EMPTY
Synonyms: sma-10(ok2224) zIs356 IV.
Alternate IDs: WB-STRAIN:ENL68, CGC_ENL68
Notes: Made_by: Encarnacin Lozano|"zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]. See strain TJ356 for additional information about zIs356. Derived from RB1739 and TJ356."
Proper citation: RRID:WB-STRAIN:WBStrain00007216 Copy
http://www.wormbase.org/db/get?name=WBStrain00007235
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: jyIs13 II.
Alternate IDs: WB-STRAIN:ERT60, CGC_ERT60
Notes: jyIs13 [act-5p::GFP::ACT-5 + rol-6(su1006)] II. Rollers with GFP localized to apical side of intestine. Reference: Szumowski SC, et al. Cell Microbiol. 2015 Jul 6. PMID:26147591.|"jyIs13 [act-5pGFPACT-5 + (pRF4) rol-6(su1006)] II. Rollers with GFP localized to apical side of intestine. Reference: Szumowski SC, et al. Cell Microbiol. 2015 Jul 6. PMID:26147591."
Proper citation: RRID:WB-STRAIN:WBStrain00007235 Copy
http://www.wormbase.org/db/get?name=WBStrain00007238
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39331715
Synonyms: pals-22(jy3) III; jyIs8[pals-5p::GFP, myo-2::mCherry] X
Alternate IDs: WB-STRAIN:ERT288
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00007238 Copy
http://www.wormbase.org/db/get?name=WBStrain00007371
Source Database: WormBase (WB)
Affected Genes: WBGene00006994(zyg-9)
Genomic Alteration: WBGene00006994(zyg-9)
Availability: available
Source References: PMID:37603562
Synonyms: zyg-9(or634) II.
Alternate IDs: WB-STRAIN:EU1510, CGC_EU1510
Notes: Supplementary_genotype zyg-9 (or634ts) II|"Temperature sensitive. Maintain at 15C. At 26C, animals give rise to 100% dead embryos, with embryos exhibiting lack of pronuclear migration at the one-cell stage. At 15C, animals give rise to viable progeny."
Proper citation: RRID:WB-STRAIN:WBStrain00007371 Copy
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