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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00054867
Source Database: WormBase (WB)
Affected Genes: WBGene00001170(egl-1)|WBGene00003598(nhl-2)|WBGene00006331(sup-26)
Genomic Alteration: WBGene00001170(egl-1), WBGene00003598(nhl-2), WBGene00006331(sup-26)
Availability: unknown
Source References: EMPTY
Synonyms: sup-26(cdb99) nhl-2(cdb100) III; egl-1(cdb97) V.
Notes: nhl-2(cdb100) contains engineered mutations in the mir-35 binding site in the nhl-2 3UTR region making the sequence complementary to the mir-35(cdb4) variant. egl-1(cdb97) contains engineered mutations in mir-35 binding site in the egl-1 3UTR region making the sequence complementary to the mir-35(cdb4) variant. Slightly reduced brood size at 25C. Reference: Donnelly BF, et al. (2022). Cell Reports.
Proper citation: RRID:WB-STRAIN:WBStrain00054867 Copy
http://www.wormbase.org/db/get?name=WBStrain00054900
Source Database: WormBase (WB)
Affected Genes: WBGene00001403(fbl-1)|WBGene00003020(lin-35)
Genomic Alteration: WBGene00001403(fbl-1), WBGene00003020(lin-35)
Availability: unknown
Source References: EMPTY
Synonyms: lin-35(n745) I; fbl-1(qy62[mNG+loxP::fbl-1]) IV.
Notes: CRISPR/Cas9 insertion of mNeonGreen into the endogenous fbl-1 locus in an RNAi-sensitized background. Reference: Gianakas CA, et al. J Cell Biol. 2023 Jan 2;222(1):e202112096. doi: 10.1083/jcb.202112096. PMID: 36282214.
Proper citation: RRID:WB-STRAIN:WBStrain00054900 Copy
http://www.wormbase.org/db/get?name=WBStrain00054903
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: F26E4.7(qy103[F26E4.7::mNG + LoxP]) I.
Notes: mNG tag inserted into the endogenous F26E4.7 locus. Reference: Jayadev R, et al. Sci Adv. 2022 May 20;8(20):eabn2265. doi: 10.1126/sciadv.abn2265. PMID: 35584218.
Proper citation: RRID:WB-STRAIN:WBStrain00054903 Copy
http://www.wormbase.org/db/get?name=WBStrain00054864
Source Database: WormBase (WB)
Affected Genes: WBGene00003263(mir-35)
Genomic Alteration: WBGene00003263(mir-35)
Availability: unknown
Source References: EMPTY
Synonyms: mir-35(cdb2 cdb6) II.
Notes: The seed region of the mature mir-35 is replaced with random nucleotides in mir-35(cdb2 cdb6). This mutant mir-35 has little impact on embryonic mir-35 abundance but strongly inhibits its decay at embryo to L1. Superficially wild-type. Reference: Donnelly BF, et al. (2022). Cell Reports.
Proper citation: RRID:WB-STRAIN:WBStrain00054864 Copy
http://www.wormbase.org/db/get?name=WBStrain00054865
Source Database: WormBase (WB)
Affected Genes: WBGene00003263(mir-35)
Genomic Alteration: WBGene00003263(mir-35)
Availability: unknown
Source References: EMPTY
Synonyms: mir-35(cdb2 cdb72) II.
Notes: cdb2 cdb72 is a mutation to the 3' end of the mature mir-35 creating a 3 end containing nucleotides that are not present or rare among all mir-35 family members at a given position, while preserving overall GC content. This mir-35 mutant strongly impacts embryonic abundance of mir-35 but does not affect its decay at embryo to L1. Superficially wild-type. Reference: Donnelly BF, et al. (2022). Cell Reports.|"Made_by: Bridget Donnelly"
Proper citation: RRID:WB-STRAIN:WBStrain00054865 Copy
http://www.wormbase.org/db/get?name=WBStrain00054904
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: C16E9.1(qy104[C16E9.1::mNG + LoxP]) X.
Notes: mNG tag inserted into the endogenous C16E9.1 locus. Reference: Jayadev R, et al. Sci Adv. 2022 May 20;8(20):eabn2265. doi: 10.1126/sciadv.abn2265. PMID: 35584218.
Proper citation: RRID:WB-STRAIN:WBStrain00054904 Copy
http://www.wormbase.org/db/get?name=WBStrain00054907
Source Database: WormBase (WB)
Affected Genes: WBGene00006745(unc-5)
Genomic Alteration: WBGene00006745(unc-5)
Availability: unknown
Source References: PMID:38345070
Synonyms: unc-5(qy70[unc-5::2xmNG + LoxP]) IV.
Notes: 2x mNG tag inserted into the endogenous unc-5 locus. Reference: Jayadev R, et al. Sci Adv. 2022 May 20;8(20):eabn2265. doi: 10.1126/sciadv.abn2265. PMID: 35584218.|"Made_by: Eric Hastie"
Proper citation: RRID:WB-STRAIN:WBStrain00054907 Copy
http://www.wormbase.org/db/get?name=WBStrain00054851
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: lqIs221 V.
Notes: lqIs221 [egl-17p::mab-5::GFP + gcy-32p::CFP]. AQR migration defects. AQR in the tail in the normal position of PQR. CFP expression in AQR, PQR and URXL/R. Reference: Tamayo JV, et al. BMC Genomics. 2013 May 4;14:304. doi: 10.1186/1471-2164-14-304. PMID: 23642123.
Proper citation: RRID:WB-STRAIN:WBStrain00054851 Copy
http://www.wormbase.org/db/get?name=WBStrain00054850
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: ayIs9 II; lqIs220 X.
Notes: ayIs9 [egl-17p::GFP + dpy-20(+)]. Reference: Tamayo JV, et al. BMC Genomics. 2013 May 4;14:304. doi: 10.1186/1471-2164-14-304. PMID: 23642123.lqIs221 is a Pegl-17::mab-5::gfp transgene. ayIs9 is a Pegl-17::gfp transgene. AQR migration defects. AQR in the tail in the normal position of PQR.|"Made_by: Dr. Erik Lundquist"
Proper citation: RRID:WB-STRAIN:WBStrain00054850 Copy
http://www.wormbase.org/db/get?name=WBStrain00054857
Source Database: WormBase (WB)
Affected Genes: WBGene00000913(daf-18)
Genomic Alteration: WBGene00000913(daf-18)
Availability: unknown
Source References: EMPTY
Synonyms: daf-18(syb1615) IV.
Notes: D137A. Daf-d. L1 starvation sensitive. M-cell arrest defective. daf-18(D137A) corresponds to human allele PTEN(D92A). Reference: Chen J, et al. G3 (Bethesda). 2022 12(6):jkac092. doi: 10.1093/g3journal/jkac092. PMID: 35451480.|"Made_by: Suny Biotech; Jingxian Chen"
Proper citation: RRID:WB-STRAIN:WBStrain00054857 Copy
http://www.wormbase.org/db/get?name=WBStrain00054852
Source Database: WormBase (WB)
Affected Genes: WBGene00003593(nfm-1)
Genomic Alteration: WBGene00003593(nfm-1)
Availability: unknown
Source References: EMPTY
Synonyms: nfm-1(lq132) III; lqIs80 IV; lqIs58 V.
Notes: lqIs80 [SCMp::GFP::caax] IV. lqIs58 [gcy-32::CFP] V. AQR and PQR migration defects. lq132 is a hypomorphic allele of nfm-1. GFP expression in seam cells. CFP expression in AQR, PQR and URXL/R. Reference: Sundararajan L. et al. Dev Biol. 2014 Aug 15;392(2):141-52. doi: 10.1016/j.ydbio.2014.06.009. PMID: 24954154.
Proper citation: RRID:WB-STRAIN:WBStrain00054852 Copy
http://www.wormbase.org/db/get?name=WBStrain00054854
Source Database: WormBase (WB)
Affected Genes: WBGene00001340(etr-1)
Genomic Alteration: WBGene00001340(etr-1)
Availability: unknown
Source References: EMPTY
Synonyms: etr-1(lq133) II.
Notes: Dpy. AQR and PQR migration defects. Body wall muscle defects. etr-1(lq133) is 2 bp deletion frameshift in alternatively-spliced exon 8. Reference: Ochs ME, et al. G3: Genes Genomes, Genetics. 2020 Jul 7;10(7):2365-2376. doi: 10.1534/g3.120.401182. PMID: 32398235
Proper citation: RRID:WB-STRAIN:WBStrain00054854 Copy
http://www.wormbase.org/db/get?name=WBStrain00054845
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: oskEx53250.
Notes: oskEx53250 [dat-1p::GCaMP6f + dat-1p::mCherry + lin-44p::mRFP + N2 genomic DNA cut with Pvu II (as a carrier)]. Pick animals with red fluorescence to maintain. GCaMP6f and mCherry expressed in dopaminergic neurons. Generated in N2 background. Reference: Tanimoto Y, et al. Sci Rep. 2016 May 19;6:26297. doi: 10.1038/srep26297. PMID: 27193056.
Proper citation: RRID:WB-STRAIN:WBStrain00054845 Copy
http://www.wormbase.org/db/get?name=WBStrain00054847
Source Database: WormBase (WB)
Affected Genes: WBGene00001188(egl-20)
Genomic Alteration: WBGene00001188(egl-20)
Availability: unknown
Source References: EMPTY
Synonyms: egl-20(lq42) lqIs80 IV; lqIs58 V.
Notes: lqIs80 [SCMp::GFP::caax] IV. lqIs58 [gcy-32::CFP] V. PQR migration defects: PQR in the head in the normal position of AQR. lq42 is a premature stop codon in egl-20. GFP expression in seam cells. CFP expression in AQR, PQR and URXL/R. Reference: Josephson M, et al. PLos One. 2016 Feb 10;11(2):e0148658. doi: 10.1371/journal.pone.0148658. PMID: 26863303.
Proper citation: RRID:WB-STRAIN:WBStrain00054847 Copy
http://www.wormbase.org/db/get?name=WBStrain00054842
Source Database: WormBase (WB)
Affected Genes: WBGene00022877(wago-5)
Genomic Alteration: WBGene00022877(wago-5)
Availability: unknown
Source References: EMPTY
Synonyms: wago-5(tor166[GFP::3xFLAG::wago-5]) II.
Notes: GFP and 3xFLAG tags inserted into endgonenous wago-5 locus. Reference: Seroussi U, et al. bioRxiv 2022.08.08.502013; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00054842 Copy
http://www.wormbase.org/db/get?name=WBStrain00054843
Source Database: WormBase (WB)
Affected Genes: WBGene00007297(vsra-1)
Genomic Alteration: WBGene00007297(vsra-1)
Availability: unknown
Source References: EMPTY
Synonyms: vsra-1(tor170[3xflag::vsra-1]) I.
Notes: 3xFLAG tag inserted into endgonenous vsra-1/C04F12.1 locus. Reference: Seroussi U, et al. bioRxiv 2022.08.08.502013; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00054843 Copy
http://www.wormbase.org/db/get?name=WBStrain00054839
Source Database: WormBase (WB)
Affected Genes: WBGene00019862(nrde-3)
Genomic Alteration: WBGene00019862(nrde-3)
Availability: unknown
Source References: EMPTY
Synonyms: nrde-3(tor134[3xFLAG::nrde-3]) X.
Notes: 3xFLAG tag inserted into endgonenous nrde-3 locus. Reference: Seroussi U, et al. bioRxiv 2022.08.08.502013; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00054839 Copy
http://www.wormbase.org/db/get?name=WBStrain00054838
Source Database: WormBase (WB)
Affected Genes: WBGene00006449(alg-4)|WBGene00011910(alg-3)|WBGene00017641(csr-1)|WBGene00020707(wago-10)
Genomic Alteration: WBGene00006449(alg-4), WBGene00011910(alg-3), WBGene00017641(csr-1), WBGene00020707(wago-10)
Availability: unknown
Source References: EMPTY
Synonyms: alg-4(tm1184) III; csr-1(tor67[csr-1 exon2::gfp::3xflag (IV:7958598)], csr-1(mg660[G120*])) alg-3(tm1155) IV; wago-10(tor133) V.
Notes: Made_by: Amanda Charlesworth|"Quadruple mutant of four spermatogenesis-specific ago genes. Reference: Charlesworth AG, et al. Nucleic Acids Res. 2021 Sep 7;49(15):8836-8865. PMID: 34329465"
Proper citation: RRID:WB-STRAIN:WBStrain00054838 Copy
http://www.wormbase.org/db/get?name=WBStrain00054892
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: qyIs23 II; IqIs80 IV.
Notes: qyIs23 [cdh-3p::mCherry::PLCdPH + unc-119(+)] II. lqIs80 [SCMp::GFP::caax] IV. Utse and seam markers. Reference: Gianakas CA, et al. J Cell Biol. 2023 Jan 2;222(1):e202112096. doi: 10.1083/jcb.202112096. PMID: 36282214.
Proper citation: RRID:WB-STRAIN:WBStrain00054892 Copy
http://www.wormbase.org/db/get?name=WBStrain00054895
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: qySi99 I.
Notes: qySi99 [lin-29p::fdgt-1::mNG] I. Single-copy insertion of mNG-tagged fdgt-1. fdgt-1 formerly known as fgt-1. Reference: Garde A, et. al. Dev. Cell. 2022 Mar 28;57(6):732-749.e7. PMID: 35316617|"qySi99 [lin-29p::fgt-1::mNG] I. Single-copy insertion of mNG-tagged fgt-1. Reference: Garde A, et. al. Dev. Cell. 2022 Mar 28;57(6):732-749.e7. PMID: 35316617"
Proper citation: RRID:WB-STRAIN:WBStrain00054895 Copy
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