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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00005265
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00006070(str-2)|WBGene00006575(tir-1)
Genomic Alteration: WBGene00001864(him-5), WBGene00006070(str-2), WBGene00006575(tir-1)
Availability: available
Source References: PMID:10571181
Synonyms: kyIs140 I; tir-1(ky388) III; him-5(e1490) V.
Alternate IDs: WB-STRAIN:CX4828, CGC_CX4828
Notes: kyIs140 [str-2::GFP + lin-15(+)] I. Him. In tir-1 mutants str-2::GFP is expressed in both AWC neurons.
Proper citation: RRID:WB-STRAIN:WBStrain00005265 Copy
http://www.wormbase.org/db/get?name=WBStrain00005266
Source Database: WormBase (WB)
Affected Genes: WBGene00003822(nsy-1)|WBGene00006070(str-2)
Genomic Alteration: WBGene00003822(nsy-1), WBGene00006070(str-2)
Availability: available
Source References: PMID:10571181
Synonyms: kyIs140 I; nsy-1(ky397) II.
Alternate IDs: WB-STRAIN:CX4998, CGC_CX4998
Notes: kyIs140 [str-2::GFP + lin-15(+)] I. In nsy-1 mutants str-2::GFP is expressed in both AWC neurons.
Proper citation: RRID:WB-STRAIN:WBStrain00005266 Copy
http://www.wormbase.org/db/get?name=WBStrain00005264
Source Database: WormBase (WB)
Affected Genes: WBGene00003839(ocr-2)
Genomic Alteration: WBGene00003839(ocr-2)
Availability: available
Source References: PMID:38302462, PMID:38396085
Synonyms: ocr-2(ak47) IV.
Alternate IDs: WB-STRAIN:CX4544, CGC_CX4544
Notes: Chemosensory, mechanosensory, and osmosensory defects. Null allele. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.|"WBStrain provided so WBPaper00061436 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00005264 Copy
http://www.wormbase.org/db/get?name=WBStrain00005262
Source Database: WormBase (WB)
Affected Genes: WBGene00003838(ocr-1)
Genomic Alteration: WBGene00003838(ocr-1)
Availability: available
Source References: PMID:38302462
Synonyms: ocr-1(ok132) V.
Alternate IDs: WB-STRAIN:CX4533, CGC_CX4533
Notes: Double mutants with ocr-2 have reduced AWA gene expression.
Proper citation: RRID:WB-STRAIN:WBStrain00005262 Copy
http://www.wormbase.org/db/get?name=WBStrain00005277
Source Database: WormBase (WB)
Availability: available
Source References: PMID:32857970, PMID:37603562
Synonyms: kyIs262 IV.
Alternate IDs: WB-STRAIN:CX5974, CGC_CX5974
Notes: kyIs262 [unc-86::myr::GFP + odr-1::RFP] IV.|"WBStrain mapped, WBPaper00060142 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00005277 Copy
http://www.wormbase.org/db/get?name=WBStrain00005272
Source Database: WormBase (WB)
Affected Genes: WBGene00004854(slt-1)
Genomic Alteration: WBGene00004854(slt-1)
Availability: available
Synonyms: slt-1(ok255) X.
Alternate IDs: WB-STRAIN:CX5463, CGC_CX5463
Notes: Made_by: OMRF Knockout Group|"Viable. Can be scored only using special neuronal markers such as zdIs5 [mec-4p::GFP + lin-15(+)], which labels the touch cells and shows that they have aberrant anterior processes in the slt-1 mutant."
Proper citation: RRID:WB-STRAIN:WBStrain00005272 Copy
http://www.wormbase.org/db/get?name=WBStrain00005273
Source Database: WormBase (WB)
Affected Genes: WBGene00023497(lin-15B)|WBGene00023498(lin-15A)
Genomic Alteration: WBGene00023497(lin-15B), WBGene00023498(lin-15A)
Availability: available
Synonyms: lin-15B&lin-15A(n765) X; kyEx581.
Alternate IDs: WB-STRAIN:CX5478, CGC_CX5478
Notes: kyEx581 [ocr-4::GFP + lin-15(+)]. GFP expression in OLQS. Maintain by picking non-Muv.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00005273 Copy
http://www.wormbase.org/db/get?name=WBStrain00005270
Source Database: WormBase (WB)
Affected Genes: WBGene00004854(slt-1)
Genomic Alteration: WBGene00004854(slt-1)
Availability: available
Synonyms: slt-1(ev740) X.
Alternate IDs: WB-STRAIN:CX5346, CGC_CX5346
Notes: AVM axon guidance defect.
Proper citation: RRID:WB-STRAIN:WBStrain00005270 Copy
http://www.wormbase.org/db/get?name=WBStrain00005267
Source Database: WormBase (WB)
Affected Genes: WBGene00004854(slt-1)
Genomic Alteration: WBGene00004854(slt-1)
Availability: available
Synonyms: slt-1(eh15) X.
Alternate IDs: WB-STRAIN:CX5000, CGC_CX5000
Notes: Made_by: David Hughes/Joe Hao|"slt-1 mutants have no dissecting-scope phenotype. They have a 40% penetrant defect in the ventral guidance of the AVM neuron scored with mec-4::GFP, a mild defect in CAN cell migration that is enhanced by a ceh-23::GFP transgene, and a mild defect in midline crossing by PVQ neurons scorable with sra-6::GFP. slt-1(eh15) is a complex rearrangement that duplicates the endogenous slt-1 gene, but disrupts both duplicated copies. The two copies are linked on X but the exact distance between them is not known. The duplication probably extends >13 kb based on Southern blotting. Deletion breakpoints for the first copy of slt-1 are as follows: nucleotides 26219 to 28163 and 28197 to 28294 in cosmid C26G2 are deleted. The second copy of slt-1 contains the following structure: nucleotides 28197 to 28294 in C26G2 are deleted, followed by a duplication of nucleotides 28300 to 28396 in C26G2 that begins 5 nucleotides after the deletion. Both copies of slt-1 are mutant, as confirmed by both DNA sequence and RT-PCR analysis of slt-1 mRNA. Scoring for homozygosity of the slt-1 allele by PCR is difficult because of the two copies of the gene and because the small deletion and the small duplication of the second copy of slt-1 are the same size. The mutant can be followed indirectly by X linkage (very closely linked to unc-3). It may be possible to make a specific primer within the duplicated region that detects a unique band in the slt-1 mutant."
Proper citation: RRID:WB-STRAIN:WBStrain00005267 Copy
http://www.wormbase.org/db/get?name=WBStrain00005300
Source Database: WormBase (WB)
Availability: available
Source References: PMID:22301316, PMID:33820969, PMID:38564369
Synonyms: Caenorhabditis elegans wild isolate.
Alternate IDs: WB-STRAIN:CX11264, CGC_CX11264
Notes: C. elegans wild isolate. Reference: Andersen EC, et al. Nat Genet. 2012 Jan 29;44(3):285-90.|"Made_by: A. Sivasundar"
Proper citation: RRID:WB-STRAIN:WBStrain00005300 Copy
http://www.wormbase.org/db/get?name=WBStrain00005282
Source Database: WormBase (WB)
Affected Genes: WBGene00001135(eat-4)
Genomic Alteration: WBGene00001135(eat-4)
Availability: available
Synonyms: eat-4(ky5) III; kyEx844.
Alternate IDs: WB-STRAIN:CX6827, CGC_CX6827
Notes: kyEx844 contains [odr-3::eat-4 + elt-2::GFP].
Proper citation: RRID:WB-STRAIN:WBStrain00005282 Copy
http://www.wormbase.org/db/get?name=WBStrain00005278
Source Database: WormBase (WB)
Affected Genes: WBGene00002141(inx-19)
Genomic Alteration: WBGene00002141(inx-19)
Availability: available
Source References: PMID:38302462
Synonyms: inx-19(ky634) I.
Alternate IDs: WB-STRAIN:CX6161, CGC_CX6161
Notes: Previously called nsy-5.
Proper citation: RRID:WB-STRAIN:WBStrain00005278 Copy
http://www.wormbase.org/db/get?name=WBStrain00005210
Source Database: WormBase (WB)
Affected Genes: WBGene00006749(unc-9)
Genomic Alteration: WBGene00006749(unc-9)
Availability: available
Synonyms: unc-9(fc16) X.
Alternate IDs: WB-STRAIN:CW129, CGC_CW129
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00005210 Copy
http://www.wormbase.org/db/get?name=WBStrain00005211
Source Database: WormBase (WB)
Affected Genes: WBGene00001520(gas-1)
Genomic Alteration: WBGene00001520(gas-1)
Availability: available
Source References: PMID:9952163, PMID:33542359, PMID:33713125, PMID:33640978, PMID:37957360
Synonyms: gas-1(fc21) X.
Alternate IDs: WB-STRAIN:CW152, CGC_CW152
Notes: Hypersensitive to volatile anesthetics. Temperature sensitive hypomorph and should be propagated at or below 20C. Low brood size.|"Supplementary_genotype gas-1(fc21) X"|"WBStrain mapped, WBPaper00061258 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00005211 Copy
http://www.wormbase.org/db/get?name=WBStrain00005293
Source Database: WormBase (WB)
Affected Genes: WBGene00007119(calf-1)
Genomic Alteration: WBGene00007119(calf-1)
Availability: available
Source References: PMID:38302462
Synonyms: calf-1(ky867) V.
Alternate IDs: WB-STRAIN:CX10207, CGC_CX10207
Notes: Saheki Y, Bargmann CI. Nat Neurosci. 2009 Oct;12(10):1257-65.
Proper citation: RRID:WB-STRAIN:WBStrain00005293 Copy
http://www.wormbase.org/db/get?name=WBStrain00005209
Source Database: WormBase (WB)
Affected Genes: WBGene00006811(unc-79)
Genomic Alteration: WBGene00006811(unc-79)
Availability: available
Synonyms: unc-79(ec1) III.
Alternate IDs: WB-STRAIN:CW16, CGC_CW16
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00005209 Copy
http://www.wormbase.org/db/get?name=WBStrain00005207
Source Database: WormBase (WB)
Affected Genes: WBGene00016630(acer-1)
Genomic Alteration: WBGene00016630(acer-1)
Availability: available
Synonyms: acer-1(rj15) II.
Alternate IDs: WB-STRAIN:CV385, CGC_CV385
Notes: acer-1(rj15) is a 7 nt deletion (removes nt 35-41 from the start codon) resulting in an out-of-frame deletion. Increased histone acetylation. Reference: Gao J, et al., PLoS Genet. 2015 Mar 13;11(3):e1005029.
Proper citation: RRID:WB-STRAIN:WBStrain00005207 Copy
http://www.wormbase.org/db/get?name=WBStrain00005203
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00019247(syp-4)
Genomic Alteration: WBGene00000254(bli-4), WBGene00019247(syp-4)
Availability: available
Synonyms: syp-4(tm2713) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:CV87, CGC_CV87
Notes: Homozygous lethal allele balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP syp-4(tm2713) homozygotes (viable but throw 97% dead eggs, 40% males). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Smolikove S, et al. (2009) PLoS Genet 5(10):e1000669.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00005203 Copy
http://www.wormbase.org/db/get?name=WBStrain00005204
Source Database: WormBase (WB)
Affected Genes: WBGene00001078(dpy-19)|WBGene00001609(glp-1)|WBGene00011415(him-18)
Genomic Alteration: WBGene00001078(dpy-19), WBGene00001609(glp-1), WBGene00011415(him-18)
Availability: available
Source References: PMID:36176234
Synonyms: him-18(tm2181)/qC1 [dpy-19(e1259) glp-1(q339) qIs26] III.
Alternate IDs: WB-STRAIN:CV98, CGC_CV98
Notes: Mutagen:UV/TMP|"qIs26 [lag-2::GFP + rol-6(su1006)]. Heterozygous animals show roller phenotype and GFP signal at the distal tip cells. Segregates roller GFP(+) heterozygotes, wild-type moving GFP(-) him-18(tm2181) homozygotes. qC1 [dpy-19(e1259) glp-1(q339) qIs26] homozygous animals are dead. P0 him-18(tm2181) homozygous animals show 80% embryonic lethality and 12% high incidence of male at F1. Pick roller GFP(+) worms to maintain. Reference: Saito TT, et al. (2009) PLoS Genet 5:e1000735."|"Supplementary_genotype him-18(tm2181)III/qCq dpy-19(e1259)glp-1(q339)nls189 III"
Proper citation: RRID:WB-STRAIN:WBStrain00005204 Copy
http://www.wormbase.org/db/get?name=WBStrain00005202
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00020068(cra-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00020068(cra-1)
Availability: available
Synonyms: cra-1(tm2144) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:CV78, CGC_CV78
Notes: Homozygous lethal allele balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP cra-1(tm2144) homozygotes (99.7% embryonic lethality, 61% larval lethality, Him). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Smolikove S, et al. (2008) PLoS Genet 4(6):e1000088.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00005202 Copy
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