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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
New England Biolabs
 
Resource Report
Resource Website
10000+ mentions
New England Biolabs (RRID:SCR_013517) commercial organization An Antibody supplier. is parent organization of: InBase
is parent organization of: Polbase
is parent organization of: REBASE
is parent organization of: NEBcutter
Crossref funder ID: 100004774, nlx_152420, Wikidata: Q17134414, ISNI: 0000 0004 0376 1796, grid.273406.4 https://ror.org/04ywg3445 SCR_013517 2026-07-25 12:07:50 50730
NEBcutter
 
Resource Report
Resource Website
100+ mentions
NEBcutter (RRID:SCR_010664) data analysis service, service resource, production service resource, analysis service resource This tool will take a DNA sequence and find the large, non-overlapping open reading frames using the E.coli genetic code and the sites for all Type II and commercially available Type III restriction enzymes that cut the sequence just once. By default, only enzymes available from NEB are used, but other sets may be chosen. Just enter your sequence and submit. Further options will appear with the output. The maximum size of the input file is 1 MByte, and the maximum sequence length is 300 KBases. NEBcutter produces a variety of outputs including restriction enzyme maps, theoretical digests and links into the restriction enzyme database, REBASE (http://rebase.neb.com/rebase/rebase.html). Importantly, its table of recognition sites is updated daily from REBASE and it marks all sites that are potentially affected by DNA methylation (Dam, Dcm, etc.). Many options exist to choose the enzymes used for digestion, including all known specificities, subsets of those that are commercially available or sets of enzymes that produce compatible termini. bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: New England Biolabs
PMID:12824395 biotools:nebcutter, nlx_71778 https://bio.tools/nebcutter SCR_010664 2026-07-31 09:27:09 142
InBase
 
Resource Report
Resource Website
10+ mentions
InBase (RRID:SCR_003881) data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. InBase is a curated database devoted to inteins. It developed by a commercial laboratory, New England BioLabs, that also provides products related to enzyme digests on the same website. Users can access the Intein Registry, to discover properties of individual inteins. They can also submit intein data, browse intein motfis, and view mechanisms and introductions to protein splicing. has parent organization: New England Biolabs PMID:10592269
PMID:11752343
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-03020 http://www.neb.com/neb/inteins.html SCR_003881 InBase 2026-07-28 09:40:49 11
REBASE
 
Resource Report
Resource Website
100+ mentions
REBASE (RRID:SCR_007886) REBASE data or information resource, database Database of information about restriction enzymes and related proteins containing published and unpublished references, recognition and cleavage sites, isoschizomers, commercial availability, methylation sensitivity, crystal, genome, and sequence data. DNA methyltransferases, homing endonucleases, nicking enzymes, specificity subunits and control proteins are also included. Several tools are available including REBsites, BLAST against REBASE, NEBcutter and REBpredictor. Putative DNA methyltransferases and restriction enzymes, as predicted from analysis of genomic sequences, are also listed. REBASE is updated daily and is constantly expanding. Users may submit new enzyme and/or sequence information, recommend references, or send them corrections to existing data. The contents of REBASE may be browsed from the web and selected compilations can be downloaded by ftp (ftp.neb.com). Additionally, monthly updates can be requested via email., endonuclease, enzyme, genome, archaeal, bacterial, cleavage, crystal, dna, individual protein family databases, isochizomer, methylation, methyltransferase, modification, protein, recognition, restriction, restriction enzyme, sensitivity, sequence, site, methylase, cleavage site, restriction-modification, blast, FASEB list has parent organization: New England Biolabs
works with: Webcutter
New England Biolabs Inc ;
NLM LM04971
PMID:19846593
PMID:17202163
r3d100012171, nif-0000-03391 http://rebase.neb.com, https://doi.org/10.17616/R3J930 http://www.neb.com/rebase SCR_007886 The Restriction Enzyme Database, Restriction Enzyme Database 2026-07-28 09:41:55 246
Polbase
 
Resource Report
Resource Website
Polbase (RRID:SCR_006107) data or information resource, data repository, storage service resource, database, service resource Repository of biochemical, genetic, and structural information about DNA Polymerases. Polbase is designed to compile detailed results of polymerase experimentation, presenting them in a dynamic view to inform further research. After validation, results from references are displayed in context with relevant experimental details and are always traceable to their source publication. Polbase is connected to other resources, including PubMed, UniProt and the RCSB Protein Data Bank, to provide multi-faceted views of polymerase knowledge. In addition to a simple web interface, Polbase data is exposed for custom analysis by external software. dna polymerase repository, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: PubMed
is related to: UniProt
has parent organization: New England Biolabs
Small Business Innovation Research ;
NIGMS 1R44GM087021
PMID:21993301 Free, Open unspecified license, Acknowledgement required biotools:polbase, nlx_151580 https://bio.tools/polbase SCR_006107 DNA Polymerase Database 2026-07-31 09:26:22 0

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