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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Beckman Coulter Resource Report Resource Website 100+ mentions |
Beckman Coulter (RRID:SCR_008940) | commercial organization | An Organization portal, Material service resource, Antibody supplier, Instrument supplier | biotechnology, diagnostic, life science, biomedical, testing, analyzer, immunochemistry, dna analysis, flow cytometer |
is related to: ONE Study is parent organization of: Diagnostic Systems Laboratories |
nlx_152293 | SCR_008940 | Beckman Coulter Inc. | 2026-08-15 11:23:52 | 160 | |||||||||
|
ONE Study Resource Report Resource Website 10+ mentions |
ONE Study (RRID:SCR_003886) | ONE Study | portal, consortium, data or information resource, organization portal | Consortium aiming to produce regulatory T cells that are compatible with a kidney transplant patient''''s immune system, as a measure to suppress the body''''s natural immune response against a transplanted organ. If successful, this approach will reduce a transplantation patient''''s life-long dependency on immune suppressing drugs, many of which are often associated with undesirable side effects and can limit the patient''''s daily routine. The consortium goals are to develop and conduct clinical trials of various immunoregulatory T-cell-based products in organ transplantation recipients, allowing a direct comparison of the safety, clinical practicality and therapeutic efficacy of each cell type. The central focus of the project is to: # Production and manufacture of distinct populations of hematopoietic immunoregulatory T cells # Comparatively study the tolerogenic characteristics of these regulatory cell types # Test these cell therapy products side by side in a clinical trial living donor renal transplant recipients The first workstream will work with different T regulatory cell, tolerogenic DC and suppressive macrophage cell products that are currently in development. In addition to these therapeutics, another goal of this workstream is to develop a cell tracking technology that assesses pharmacodynamics and pharmacokinetics of these cell-based therapies. The second workstream is focused on designing and conducting a cell therapy based clinical trial in renal transplantation, taking into consideration ethics, concurrent immunosuppressive drug use, state-of-the-art immune monitoring, innovative all-in-one data capturing systems, and pharmacovigilance. The goal is to have a comparative evaluation of hematopoietic cell therapy safety in renal transplantation. The third workstream aims to learn more about the specific comparative characteristics of suppressive cell types and to use this knowledge to improve later trial designs and foster novel ideas for new or improved suppressive / tolerogenic cell population. | immune response, organ transplant, kidney, clinical trial, cell therapy, clinical, immune system, tool development, basic research, healthcare, drug development, transplant surgery, immunosuppression, hematopoietic immunoregulatory cell |
is listed by: Consortia-pedia is related to: University of Regensburg; Bavaria; Germany is related to: King's College London; London; United Kingdom is related to: University of Oxford; Oxford; United Kingdom is related to: Charite - Universitatsmedizin Berlin; Berlin; Germany is related to: Fondazione Centro San Raffaele; Milan; Italy is related to: Loughborough University; Loughborough; United Kingdom is related to: University of Wisconsin-Madison; Wisconsin; USA is related to: University of California at San Francisco; California; USA is related to: Miltenyi Biotec is related to: Electro Scientific Industries is related to: Beckman Coulter is related to: KOEHLER eClinical is related to: Pharmatching is related to: ALTA |
European Union FP7 | nlx_158215 | SCR_003886 | A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation, The ONE Study - A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation, The ONE Study | 2026-08-20 09:26:19 | 21 | |||||||
|
Diagnostic Systems Laboratories Resource Report Resource Website 10+ mentions |
Diagnostic Systems Laboratories (RRID:SCR_013524) | material resource, commercial organization, antibody supplier, reagent supplier | An Antibody supplier. Is part of Beckman Coulter. | has parent organization: Beckman Coulter | nlx_152346 | SCR_013524 | Diagnostic Systems Laboratories inc. | 2026-08-20 09:29:07 | 12 |
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