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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Inspiralis
 
Resource Report
Resource Website
1+ mentions
Inspiralis (RRID:SCR_004082) commercial organization Commercial organization supplying topoisimerase products and services to the pharmaceutical industry and academia to aid research in the anti-infectives and anti-cancer markets. Their aim is to provide pharmaceutical companies, and others involved in drug development, with the necessary tools to develop and screen novel anti-infective and anti-cancer compounds. Products All their proteins are expressed as the native sequences without additional tags. The only exception is the M. tuberculosis gyrase which is currently produced with a C-terminal His tag. An untagged version of this protein will be available soon. * Topoisomerase Enzymes and Assay Kits * Specific Gyrase Protein Domains * DNA Substrates and Markers * Antibodies Services * Gel Based Assays * Medium / High Throughput Assay * Investigation protein DNA interaction ReDCaT chip topoisomerase, enzyme, substrate, drug development, anti-infective, anti-cancer, assay, protein-dna interaction, protein, dna is related to: European Gram Negative AntiBacterial Engine nlx_158540 SCR_004082 Inspiralis Limited, Inspiralis Ltd 2026-09-03 04:46:58 4
European Gram Negative AntiBacterial Engine
 
Resource Report
Resource Website
1+ mentions
European Gram Negative AntiBacterial Engine (RRID:SCR_003859) ENABLE consortium, data or information resource, organization portal, portal Consortium working to advance the development of potential antibiotics against Gram-negative bacteria, such as Escherichia coli. The project creates and manages a drug discovery engine for testing and optimizing molecules that are still in the earlier stages of drug discovery but have the potential to become future drug candidates capable of treating resistant Gram-negative infections. The project will focus on the discovery and pre-clinical stages of drug development, as well as (potentially) phase 1 clinical trials. ENABLE will run several drug discovery programs in parallel and the consortium seeks external hit and lead programs to join, through a series of open calls during the project. Researchers who have interesting molecules will have the opportunity to collaborate with a diverse range of experts in microbiology, pharmacology and chemistry to help advance their molecule through the drug development process until it is an attractive candidate for clinical testing. Specifically, the project is working towards: # identifying three antibacterial lead molecules which, following extensive testing, have been identified as having promising antimicrobial activity; # identifying two antibacterial clinical candidate molecules # advancing at least one compound into preclinical and phase 1 clinical studies, i.e. early clinical safety testing in humans. drug, drug discovery, drug candidate, molecule, antibiotic, antimicrobial resistance, drug development, tool development, basic research, clinical trial, pre-clinical, antimicrobial, antibacterial, gram-negative bacteria is listed by: Consortia-pedia
is related to: Spanish National Research Council; Madrid; Spain
is related to: Aston University; Birmingham; United Kingdom
is related to: Cardiff University; Wales; United Kingdom
is related to: European Biotechnology Network
is related to: MEDINA Foundation
is related to: University of Helsinki; Helsinki; Finland
is related to: Hvidovre Hospital; Hvidovre; Denmark
is related to: John Innes Centre; Norwich; United Kingdom
is related to: University of Copenhagen; Copenhagen; Denmark
is related to: Latvian Institute of Organic Synthesis; Riga; Latvia
is related to: National Medicines Institute; Warsaw; Poland
is related to: SP Process Development; Sodermanland; Sweden
is related to: University of Oxford; Oxford; United Kingdom
is related to: University of Barcelona; Barcelona; Spain
is related to: University of Liege; Wallonia; Belgium
is related to: Uppsala University; Uppsala; Sweden
is related to: Asclepia MedChem Solutions
is related to: Beactica
is related to: Biomol-Informatics
is related to: Inspiralis
is related to: KeytoLead
is related to: Molecular Discovery
is related to: MPS Hamburg
is related to: OnTarget Chemistry
has parent organization: Uppsala University; Uppsala; Sweden
Innovative Medicines Initiative ;
New Drugs for Bad Bugs ND4BB program ;
EFPIA
nlx_158183 SCR_003859 European Gram Negative Antibacterial Engine (ENABLE), European Gram-negative Antibacterial Engine 2026-09-03 04:46:42 4

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