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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.cancerresearchuk.org/
Cancer Research UK is UK's largest charity funding cancer research. Cancer Research UK is a registered charity in England and Wales (1089464) and in Scotland (SC041666). Registered as a company limited by guarantee in England & Wales No. 4325234.
Proper citation: Cancer Research UK (RRID:SCR_004041) Copy
Core offers standard and specialised histology services including tissue processing (murine, human and Drosophila tissue), processing of cellular material (cells, crypt cultures, organoids and spheroids), microtomy, cryo-microtomy, haematoxylin and eosin and specialised tissue stains along with automated immunohistochemical/ immunofluorescence/ in situ hybridisation analysis for specific labelling of individual tissue constituents.
Proper citation: Cancer Research UK Scotland Institute Histology Service Core Facility (RRID:SCR_028690) Copy
canSAR is an integrated database that brings together biological, chemical, pharmacological (and eventually clinical) data. Its goal is to integrate this data and make it accessible to cancer research scientists from multiple disciplines, in order to help with hypothesis generation in cancer research and support translational research. This cancer research and drug discovery resource was developed to utilize the growing publicly available biological annotation, chemical screening, RNA interference screening, expression, amplification and 3D structural data. Scientists can, in a single place, rapidly identify biological annotation of a target, its structural characterization, expression levels and protein interaction data, as well as suitable cell lines for experiments, potential tool compounds and similarity to known drug targets. canSAR has, from the outset, been completely use-case driven which has dramatically influenced the design of the back-end and the functionality provided through the interfaces. The Web interface provides flexible, multipoint entry into canSAR. This allows easy access to the multidisciplinary data within, including target and compound synopses, bioactivity views and expert tools for chemogenomic, expression and protein interaction network data.
Proper citation: canSAR (RRID:SCR_006794) Copy
Offers processing fixed tissue for paraffin-embedded histology, cryo-microtomy, cell pellet processing, H+E staining and special histology stains or cellular material supplied. Immunohistochemistry, immunofluorescence and in-situ hybridisation service is available along with the capability to provide digital scanning and analysis. Many other techniques such as provision of tissue microarrays and other staining techniques such as TUNEL can be provided or set-up as required.
Proper citation: Cancer Research UK Scotland Institute Histology Core Facility (RRID:SCR_027306) Copy
https://www.crukscotlandinstitute.ac.uk/advanced-technologies/translational-molecular-imaging.html
Core provides expertise in radiochemistry, PET tracer development, preclinical PET and MRI imaging, cancer modelling, and advanced image analysis. Supports translational imaging research, with strengths in molecular imaging, pharmacodynamic biomarker development, and AI-enabled image analytics. Provided instruments include a GE PETtrace 800 cyclotron, radiosynthesis platforms, and small-animal NanoScan PET/MRI system. Services include expertise in both PET and MRI acquisition and analysis, supporting studies in cancer biology, metabolism, and therapy response.
Proper citation: Cancer Research UK Scotland Translational Molecular Imaging Group Core Facility (RRID:SCR_028697) Copy
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