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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MRC Laboratory of Molecular Biology
 
Resource Report
Resource Website
100+ mentions
MRC Laboratory of Molecular Biology (RRID:SCR_003527) LMB institution The MRC Laboratory of Molecular Biology (LMB) has long been, and remains, a world-class research laboratory. Our primary goal is to understand biological processes at the molecular level, through the application of methods drawn from physics, chemistry and genetics. This quest extends from structural studies of individual macromolecules, through their interactions and beyond to the functioning of subcellular systems, cells and multicellular systems in whole organisms, with the ultimate aim of using this knowledge to tackle specific problems in human health and disease. The LMB is one of the birthplaces of modern molecular biology. Many techniques were pioneered at the laboratory, most notably methods for determining the three-dimensional structure of proteins and DNA sequencing. Whole genome sequencing was initiated at the LMB. Another landmark discovery was the invention of monoclonal antibodies. Over the years, the work of LMB scientists has attracted 9 Nobel Prizes, shared between 13 LMB scientists, as well as numerous other prizes and scientific awards. FASEB list is parent organization of: DBD: Transcription factor prediction database
is parent organization of: FlyTF.org
is parent organization of: SCOP: Structural Classification of Proteins
is parent organization of: iMosflm
is parent organization of: Coot
is parent organization of: AIMLESS
is parent organization of: CTFFIND
is parent organization of: NeuroAnatomy Toolbox
MRC Wikidata: Q185800, nif-0000-38323, grid.42475.30, ISNI: 0000 0004 0605 769X https://ror.org/00tw3jy02 SCR_003527 2026-08-01 12:02:22 441
DBD: Transcription factor prediction database
 
Resource Report
Resource Website
10+ mentions
DBD: Transcription factor prediction database (RRID:SCR_002300) DBD service resource, database, data or information resource Database of predicted transcription factors in completely sequenced genomes. The predicted transcription factors all contain assignments to sequence specific DNA-binding domain families. The predictions are based on domain assignments from the SUPERFAMILY and Pfam hidden Markov model libraries. Benchmarks of the transcription factor predictions show they are accurate and have wide coverage on a genomic scale. The DBD consists of predicted transcription factor repertoires for 930 completely sequenced genomes. predicted transcription factor, transcription factor, dna-binding domain, proteome, sequence, domain family, protein sequence, genome, prediction is listed by: OMICtools
is related to: SUPERFAMILY
is related to: Pfam
has parent organization: MRC Laboratory of Molecular Biology
PMID:18073188
PMID:16381970
Acknowledgement requested nif-0000-02726, OMICS_00531 SCR_002300 DNA-binding domain 2026-08-06 09:25:37 10
NeuroAnatomy Toolbox
 
Resource Report
Resource Website
1+ mentions
NeuroAnatomy Toolbox (RRID:SCR_017248) NAT software resource, data analysis software, 3d visualization software, data processing software, data visualization software, software application Software R package for 3D visualisation and analysis of biological image data, especially tracings of single neurons. 3D, visualization, analysis, data, image, single, neuron, tracing is listed by: OMICtools
is related to: R Project for Statistical Computing
has parent organization: MRC Laboratory of Molecular Biology
Restricted OMICS_18884 http://jefferislab.github.io., https://CRAN.R-project.org/package=nat SCR_017248 nat, , NeuroAnatomy Toolbox 2026-08-06 09:29:01 4
SCOP: Structural Classification of Proteins
 
Resource Report
Resource Website
50+ mentions
SCOP: Structural Classification of Proteins (RRID:SCR_007039) database, data or information resource The Structural Classification of Proteins (SCOP) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationships. Protein domains in SCOP are hierarchically classified into families, superfamilies, folds and classes. The continual accumulation of sequence and structural data allows more rigorous analysis and provides important information for understanding the protein world and its evolutionary repertoire. SCOP participates in a project that aims to rationalize and integrate the data on proteins held in several sequence and structure databases. As part of this project, starting with release 1.63, we have initiated a refinement of the SCOP classification, which introduces a number of changes mostly at the levels below superfamily. The pending SCOP reclassification will be carried out gradually through a number of future releases. In addition to the expanded set of static links to external resources, available at the level of domain entries, we have started modernization of the interface capabilities of SCOP allowing more dynamic links with other databases. bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: IndelFR - Indel Flanking Region Database
is related to: SUPFAM
is related to: DOMMINO - Database Of MacroMolecular INteractiOns
has parent organization: MRC Laboratory of Molecular Biology
PMID:14681400 nlx_94704, biotools:scop https://bio.tools/scop SCR_007039 Structural Classification of Proteins database, SCOP database 2026-08-06 09:26:44 98
AIMLESS
 
Resource Report
Resource Website
500+ mentions
AIMLESS (RRID:SCR_015747) software application, data processing software, software resource Data processing software for x-ray diffraction data. AIMLESS scales together multiple observations of reflections, and merges multiple observations into an average intensity. xray, differentiation, observation, reflection, scaling, scale has parent organization: MRC Laboratory of Molecular Biology PMID:23793146 Free, Available for download SCR_015747 2026-08-06 09:28:44 541
FlyTF.org
 
Resource Report
Resource Website
10+ mentions
FlyTF.org (RRID:SCR_004123) FlyTF database, data or information resource A database of genomic and protein data for Drosophila site-specific transcription factors. transcription factor, gene, annotation, genome, protein is listed by: OMICtools
has parent organization: MRC Laboratory of Molecular Biology
PMID:16613907 The community can contribute to this resource, Acknowledgement requested OMICS_00534 SCR_004123 FlyTF.org - The Drosophila Transcription Factor Database 2026-08-06 09:26:04 12
CTFFIND
 
Resource Report
Resource Website
100+ mentions
CTFFIND (RRID:SCR_016732) CTFFIND data analysis software, software application, software resource, data processing software Software tool for finding CTFs of electron micrographs. Program used for the estimation of objective lens defocus parameters from transmission electron micrographs. The program CTFFIND3 is an updated version of the program CTFFIND2. For micrographs collected on photographic film and scanned in use CTFFIND 3. For images from CCDs or direct detectors use CTFFIND 4. is listed by: SoftCite
is related to: Janelia Research
has parent organization: MRC Laboratory of Molecular Biology
MRC PMID:26278980 SCR_016732 CTFFinding, CTFFIND4, CTFFIND2, Contrast Transfer Function Finding, Contrast Transfer FunctionFinding, CTFFIND 3 2026-08-06 09:28:56 109
iMosflm
 
Resource Report
Resource Website
100+ mentions
iMosflm (RRID:SCR_014217) software application, image processing software, data processing software, software resource Software which processes diffraction data/images and produces an MTZ file of reflection indices with their intensities, standard deviations, and other parameters. The MTZ file is passed onto other programs of the CCP4 program suite for further data reduction. iMosflm processes data from CCD and pixel detectors. It is available for Windows, Mac OSX and Linux platforms. Tutorials are available at the website. image processing software, diffraction image, mtz file is affiliated with: Pointless
has parent organization: MRC Laboratory of Molecular Biology
SCR_014217 2026-08-06 09:28:16 326
Coot
 
Resource Report
Resource Website
10000+ mentions
Coot (RRID:SCR_014222) COOT software resource, model, software toolkit, data or information resource, software application, simulation software Software for macromolecular model building, model completion and validation, and protein modelling using X-ray data. Coot displays maps and models and allows model manipulations such as idealization, rigid-body fitting, ligand search, Ramachandran plots, non-crystallographic symmetry and more. Source code is available. software toolkit, simulation software, model manipulation, protein modeling, bio.tools is used by: PDB-REDO
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: MolProbity
has parent organization: MRC Laboratory of Molecular Biology
PMID:15572765 Available for download, Acknowledgement requested biotools:coot http://strucbio.biologie.uni-konstanz.de/ccp4wiki/index.php/Coot, https://bio.tools/coot SCR_014222 Crystallographic Object-Oriented Toolkit 2026-08-06 09:28:17 14789

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