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http://harvard.eagle-i.net/i/0000012e-58c7-d44f-55da-381e80000000

Core to provide gene expression data analysis service. Activities range from the provision of services to fully collaborative grant funded investigations.

Proper citation: Harvard Partners HealthCare Center for Personalized Genetic Medicine Bioinformatics Core Facility (RRID:SCR_000882) Copy   

•   Source: SciCrunch Registry

http://www.spl.harvard.edu/

A laboratory dedicated to advancing health care through utilizing computation and imaging to new areas of medicine.

Proper citation: BWH Surgical Planning Laboratory (RRID:SCR_000869) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5e5d-69c2-55da-381e80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27, 2023. Core facility that provides the following services: Storage services for -80 degrees C and -190 degrees C in secure facility.

The Biospecimen Repository provides long-term storage of clinical and research material in -80 degrees C and liquid nitrogen freezers located at Dana Farber''s Harbor Campus. Transportation of samples to and from Harbor Campus is provided by the facility for a small fee. Competitive prices are available on per box or per freezer basis in both segregated or non-segregated environments.

Proper citation: DFCI Biospecimen Repository Core Facility (RRID:SCR_009747) Copy   

•   Source: SciCrunch Registry

http://www.ohsu.edu/xd/

As the state''s only health and research university, OHSU brings together patient care, research, education of the next generation of health care providers and scientists and community service to improve the health and well-being of all Oregonians.

Proper citation: Oregon Health and Science University; Oregon; USA (RRID:SCR_009665) Copy   

•   Source: SciCrunch Registry

http://utep.eagle-i.net/i/00000134-a952-c738-bfc0-fe9780000000

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 23, 2019. Core facility that provides the following services: Zeiss LD-5 Pascal Scanning Confocal Microscope/Assisted access, Zeiss Axioskop Epifluorescence Microscope/Assisted access, Zeiss EM-10 Transmission Electron Microscope/Assisted access, Microscopy sample preparation, Observation and photography service. The Analytical Cytology Core Facility provides assistance in the designing of protocols and the use of sophisticated, well maintained and supervised equipment. Each microscope is equipped with software for image analysis, image processing and printing of digital images. Service contracts are maintained on each of the microscopes. Computers and software are regularly upgraded. Confocal workshops are held regularly to familiarize users with new techniques and new protocols. The specific aims of the Analytical Cytology Core Facility (ACCF) are: 1. to train users in the design of protocols, the fixations, sectioning, cryofixations, immunolocalizations, the use of the Zeiss EM-10, the Zeiss Axioskop epifluorescence microscope and the Zeiss Pascal scanning confocal microscope with image analysis and image processing, 2. to support new faculty in realizing their research objectives that utilize microscopy, 3. to support the productivity of the Infectious Diseases and Immunology unit, the Toxicology unit, the Neuroscience/Metabolic Disorders unit, the Statistical Consulting Laboratory and the Bioinformatics unit by assisting faculty, undergraduate, masters, doctoral and postdoctoral students in advancing biomedical research, 4. to maintain and upgrade equipment and expertise and; 5. to provide core services anticipating self-sustaining maintenance of the core facility.

Proper citation: University of Texas El Paso Analytical Cytology Core Facility (RRID:SCR_010137) Copy   

•   Source: SciCrunch Registry

http://ctsaconnect.org/

THIS RESOURCE IS NO LONGER IS SERVICE. Documented on December 5th, 2022. Semantic framework to integrate information about research activities, clinical activities, and scientific resources to facilitate the production and consumption of Linked Open Data about investigators, physicians, biomedical research resources, services, and clinical activities. The goal is to enable software to consume data from multiple sources and allow the broadest possible representation of researchers'''' and clinicians'''' activities and research products. Current research tracking and networking systems rely largely on publications, but clinical encounters, reagents, techniques, specimens, model organisms, etc., are equally valuable for representing expertise. CTSAConnect will provide linkage between semantic representations of a wide range of clinical and research data using controlled vocabularies mapped to the Unified Medical Language System (UMLS) as a bridge between the two subject areas. The data sources include data from Medicaid, hospital billing systems, CTSAShareCenter, and other CTSA resource data, eagle-i and VIVO. It allows institutions to leverage existing tools and data sources by making the information they contain more discoverable and easier to integrate. For instance, with the ISF, researchers can be characterized by organizational affiliations, grant and project participation, research resources that they have generated, and publications that they have (co)-authored. Clinicians can be characterized by training and credentials, by clinical research topic, and by the kinds of procedures and specialization that can be inferred from encounter data. LOD refers to data that has been given a specific Uniform Resource Identifier (URI), for the purpose of sharing and linking data and information on the Semantic Web. While a large amount of data is published as LOD, there remains a significant gap in the representation of research resources and clinical expertise. Researchers can be characterized by the organization to which they belong, the grants and research in which they have participated, the research topics and research resources (reagents, biospecimens, animal models) they have generated, as well as the publications they have (co)-authored. Clinician profiles on the other hand, can be defined by their credentials, clinical research topics, and the kinds of procedures and specialization that can be inferred from clinical encounter data. They believe that integrating and relating this diversity of information sources and platforms requires addressing the overlap between research resources and the attributes and activities of researchers and clinicians. CTSAconnect aims to promote integration and discovery of research activities, resources, and clinical expertise. To this end, they will publish their ontologies and LOD via their website, which will also illustrate repeatable methods and examples of how to extract, consume, and utilize this valuable new LOD using freely available tools like VIVO, eagle-i, and Google APIs. CTSAconnect is a collaboration between Oregon Health & Science University, Stony Brook University, Cornell University, Harvard University, University at Buffalo, and the University of Florida, and leverages the work of eagle-i (eagle-i.net), VIVO (vivoweb.org), and ShareCenter (ctsasharecenter.org).

Proper citation: CTSAconnect (RRID:SCR_005225) Copy   

•   Source: SciCrunch Registry

http://cancer.dartmouth.edu/res/geospatial.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. A resource to develop shared resources for the implementation of geospatial analysis for cancer research at Dartmouth. Their goal is to provide expert consultation and collaboration for research projects of NCCC members in behavior, epidemiology, and health services research. The GeoSpatial Resource also strives to educate members of the community in different aspects of geospatial analysis by providing courses through TDI and at Dartmouth College.

Proper citation: Dartmouth Geospatial Shared Resource (RRID:SCR_000874) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/martinos-center-for-biomedical-imaging-core-facility-harvard

Core facility that provides the following services: Positron emission tomography service.

The Martinos Center''''s dual mission includes translational research and technology development. The core technologies being developed and used at the center are magnetic resonance imaging (MRI) and spectroscopy (MRS), magnetoencephalography (MEG) and electroencephalograpy (EEG), near infra-red spectroscopy (NIRS) and diffuse optical tomography (DOT), Positron Emission Tomography (PET), electrophysiology, molecular imaging, and computational image analysis. A particular area of innovation at the Center is Multimodal Functional Neuroimaging which involves the integration of imaging technologies. They are also world leaders in the development of primate neuroimaging techniques. Major areas of research at the center include, psychiatric, neurologic and neurovascular disorders, basic and cognitive neuroscience, cardiovascular disease, cancer and more. With an extensive and expanding inventory of state-of-the-art imaging facilities, a world class team of investigators and collaborators, and important government, industry and private supporters, the Martinos Center is leading the way to new advances and applications in biomedical imaging.

Proper citation: MGH Martinos Center for Biomedical Imaging Core Facility (RRID:SCR_012324) Copy   

•   Source: SciCrunch Registry

https://www.joslin.org/islet-isolation-core.html

Core facility that provides the following services: Rodent and Porcine Islet Isolation Services, Training Services. The main objective of the Islet Isolation Core is to provide Islets of Langerhans to investigators in the Boston area and beyond. By receiving islets from the Core one is assured of consistent high quality and purity of islets for experiments. The Core can isolate rodent and neonatal porcine islets. This leaves the investigator to concentrate on experiments rather than the complexity of islet isolation. The Core can buy the animals or the investigator can provide their own, such as special transgenic mice. Over the last five years the Core has isolated more than 10 million islets. They also provide training and advice. The Core can provide training not only for the isolation procedure but islet viability, islet size measurement, GSIS (Glucose Stimulated Insulin Secretion), STZ-induced diabetes, transplantation under the kidney capsule, and islet graft retrieval.

Proper citation: Joslin Diabetes Center Islet Isolation Core (RRID:SCR_012299) Copy   

•   Source: SciCrunch Registry

http://www.schepens.harvard.edu/graphics

Core facility that provides the following services: Web and graphic services, Web design and content management service, Photography service. Peter Mallen is a designer and illustrator who manages a full-service web and graphics studio in a moderately sized scientific research facility, Schepens Eye Research Institute. He provides a full range of graphic design, scientific illustration, web design and development, content management, and general design and production services. His products are utilized by: faculty and scientific staff (books, scientific publications, slide shows, grant applications); professional staff (Administration, Development & Public Affairs; brochures, books, pamphlets); the general public (Institute websites) as well as clients of our 250-seat state-of-the-art conference center, Starr Center for Scientific Communications.

Proper citation: Harvard SERI Graphic Services Core (RRID:SCR_012309) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/psychiatry/research/pngu_home.aspx

Core facility that provides the following services: SNP genotyping, qPCR for CNV detection / confirmation, Genetic analysis services, DNA extraction, quantification, sample preparation, tracking, and storage. This resource provides custom genotyping (SNP, other), qPCR for CNV detection/confirmation, DNA extraction, quantification, sample preparation, tracking, and storage, and related services to further the PNGU mission of identifying and characterizing the genetic basis of psychiatric, behavioral, and neurodevelopmental disorders and to translate these discoveries to improvements in clinical care and public health.

Proper citation: MGH Psychiatric and Neurodevelopmental Genetics Unit Core Lab (RRID:SCR_012301) Copy   

•   Source: SciCrunch Registry

http://www.neurodiscovery.harvard.edu/resources/atrc.html

Core facility that provides provides state-of-the-art molecular pathology resources to the Harvard community including laser capture microscopy, DNA/RNA/miRNA quality/expression analysis, Luminex FlexMap 3D multiplex bead cytometry, and real-time PCR. The ATRC is a fee-for-use facility. For NeuroDiscovery members, the first 10 hours of training, consultation and instrument use is free. This initial period is intended to provide a first time user with preliminary data/proof of concept regarding their project, and is generally sufficient when investigators work under the aegis of ATRC staff. Thereafter, the base fee varies depending on activity and the extent of your proposed work. Project-based charge-back agreements for large projects can be negotiated with the ATRC Director, Dr. Charles Vanderburg. Although priority is given to NeuroDiscovery members investigating neurodegenerative diseases and the CNS, the facility is also available to any academic investigators within the Harvard medical community and the greater-Boston research community. Under special arrangements the facility may also be made available to the commercial sector. Please contact ATRC Director, Dr. Charles Vanderburg, for details.

Proper citation: HNDC Advanced Tissue Resource Center (RRID:SCR_012670) Copy   

•   Source: SciCrunch Registry

http://bioinformatics.hms.harvard.edu/

Core facility that offers consultations on basic questions in research computing, bioinformatics and computational biology during the initial stages of study design and grant proposals as well as for ongoing, funded studies requiring external expertise. Core has experience in large-scale data management, database design and software development. Staff members can provide assistance in quality assurance and analysis of gene expression arrays, genome-wide SNP arrays, CNV studies and different aspects of second-generation sequencing technologies such as ChIP-seq, RNA-Seq or resequencing efforts. Services also include provision of external information generated from public database, data curation and assistance on choosing the right data format and annotation standard to ensure best practices in data management and submission are being maintained.

Proper citation: Harvard Chan Bioinformatics Core (RRID:SCR_012655) Copy   

•   Source: SciCrunch Registry

http://flowcytometry.sysbio.med.harvard.edu/

Core facility that provides the following services: Sorting and analysis services. The facility houses two state-of-the-art BD analyzers with high-throughput capability, a Stratedigm benchtop analyzer, a high-speed BD cell sorter, and both Mac and PC workstations for data analysis. Sorting services are offered through the facility, as well as instrument and software training.

Proper citation: HMS Systems Biology Flow Cytometry Facility (RRID:SCR_012696) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/transgenic-mouse-models-core

Core assists investigators with developing genetically engineered rodent models of human diseases for studying mutant genes and investigating molecular mechanisms underlying pathological processes.

Proper citation: OHSU Animal Model Support Core Facility (RRID:SCR_009994) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/specimen-bank-bwh-harvard

Core facility that provides the following services: Open repositories service, Sample processing service, Medical/pathology informatics support service, BWH tissue repository service.

The Specimen Bank provides materials to investigators with IRB-approved protocols. Staff are available to assist with selection of samples appropriate for downstream applications, development of processing protocols or preparation of derivatives from clinical materials. IT Staff are also available to assist researchers with creation of queries for prospective sample collection or queries to select samples from specific cohorts. Their goal is to drive quality research in an efficient and cost-effective manner. Each year they provide tens of thousands of samples to area researchers. Getting started: Partners investigators and study staff may request a Crimson user account to help manage studies and collected materials.

Proper citation: BWH Specimen Bank (RRID:SCR_012316) Copy   

•   Source: SciCrunch Registry

http://psm.eagle-i.net/i/00000136-cb76-eea8-d2c1-4d1680000000

Molecular biology is a field with a tremendous capacity for advancing our scientific understanding of disease and human health. Our Core facility provides its users with a centralized source of expertise as well as access to sophisticated instrumentation. This strong combination of knowledge and equipment helps to increase the productivity of the scientists at PSM so that they may more quickly make discoveries that can be translated to the clinical level and thus have a measureable impact on improving health in the US and worldwide.

Proper citation: Ponce School of Medicine and Health Sciences Molecular Biology Core Laboratory (RRID:SCR_010049) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-c193-a4b9-02c0-2b6880000000

Core facility that provides the following services: Protein identification from Coommassie stained gel, Protein identification from silver stained gel, Protein identification from complex mixtures (in solution) service, Running SDS-PAGE service, SILAC (Data Acquisition and Analysis), ICAT (Data Acquisition and Analysis), ITRAQ (Data Acquisition and Analysis). The Proteomics Center at Children''s Hospital Boston offers the most up-to-date proteomics equipment currently available. This includes the latest equipment for protein separation and several state-of-the-art mass spectrometers, which detect and quantify proteins in a sample and measure them to determine their structure and characteristics.

Proper citation: Proteomics Center at Childrens Hospital Boston (RRID:SCR_010051) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-2508-afb7-43fb-601a80000000

The goal of the Biostatistical Support Service is to provide investigators expert advice on proper study design and data analysis. The support includes consults with the center biostatistician, faculty consultants from the School of Public Health, Department of Biostatistics and Epidemiology, Medical Sciences Campus, University of Puerto Rico, and use of statistical software.

Proper citation: Puerto Rico Clinical and Translational Research Consortium Biostatistic Core Laboratory (RRID:SCR_010052) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012b-00bf-9a5b-9e37-5ded80000000

The Research Subject Advocate''s main responsibility is to assure that all steps are taken throughout any clinical research activity to protect the participating subjects and to ensure that their safety is given the highest priority. Also it is her responsibility to assure that all investigators/collaborators and CRC personnel are managing patient health information according to the Health Information Portability and Accountability Act.

Proper citation: Puerto Rico Clinical and Translational Research Consortium Research Subject Advocate (RRID:SCR_010054) Copy   

•   Source: SciCrunch Registry