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http://wyss.harvard.edu/viewpage/594/

A core facility with access to imaging equipment and analysis software such as wide-field light microscopy, Total Internal Reflection Fluorescence microscopy (TIRF), confocal microscopy, Atomic Force Microscopy (AFM), Transmission Electron Microscopy (TEM), small animal imaging, spectroscopy, and flow cytometry.

Proper citation: Wyss Institute Imaging Core (RRID:SCR_000898) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-9c1a-059b-55da-381e80000000

Core facility that provides the following services: Microscope access service, Microscope training service. Confocal and multiphoton are modern fluorescence techniques in microscopy for generating optical sections from live or fixed biological specimens. In general, both techniques employ a point scanning and point detecting design. The confocal microscope achieves point detection by using a confocal pinhole to block off out-of-focus emission from the specimen. The multiphoton microscope, on the other hand, generates intrinsic point emission directly from the in-focus spot, thereby eliminating the need for a confocal pinhole. Subsequent scanning of the entire field of view results in an optical section. Computer reconstruction of serial optical sections, collected at consecutive axial (z) positions, can reveal the spatial localization of cells and tissues (sometime subcellular molecules) in 3D. The ability to see biochemical processes in live cells, in real time, sheds light on the vastly complex molecular world of cells and may allow IDI scientists to identify new targets for drugs that will treat exposure to dangerous toxins and bacteria as well as fight a wide variety of diseases.

Proper citation: Harvard PCMM Optical Microscopy Core (RRID:SCR_009854) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000139-4f2c-8328-4d8e-943b80000000

Core facility that provides the following services: Microscopy Instrumentation Access, Training in Microscopy/Imaging, Assisted Microscopy. The mission of Ragon Institute Imaging Core, Microscopy Division is to bring the latest imaging modalities and technology to bear on fundamental molecular and cell biological questions pertaining to infectious diseases. As an MGH Core Facility, the Ragon Institute Imaging Core also serves the MGH greater MGH community. Since the Ragon Institute is also a collaboration between MGH, Harvard, and MIT, so too does the facility welcome members of the MIT and Harvard communities as we are now located in Cambridge at MIT. The facility encompasses five imaging systems, including a Zeiss LSM510 laser scanning confocal microscope and a fully automated Zeiss Axio Observer microscope, both housed in BL2+ compliant facilities. These imaging systems are therefore fully equipped for both fixed and live cell imaging. In addition, the facility has two slide scanning systems (MIRAX MIDI and TissueFAXS) for high speed automated imaging and cellular screening of tissue sections and cultured cells on glass slides. In the Flow Cytometry section of the Imaging Core, we also have an ImageStream X Mark II by Amnis. The core also serves as a resource for addressing a variety of imaging needs including consultation on a topics related to imaging applications, experimental design, and sample preparation.

Proper citation: Ragon Institute Imaging Core Microscopy (RRID:SCR_010058) Copy   

•   Source: SciCrunch Registry

https://childrenshospital.corefacilities.org/service_center/show_external/3145

Core with advanced instrumentation in Light and Electron Microscopy.Core provides confocal, multiphoton microscopy,electron microscopy,image analysis.

Proper citation: Harvard Medical School PCMM Microscopy Core Facility (RRID:SCR_018822) Copy   

•   Source: SciCrunch Registry