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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Johns Hopkins University is private research university in Baltimore, Maryland. Founded in 1876, university was named for its first benefactor, American entrepreneur, abolitionist, and philanthropist Johns Hopkins.
Proper citation: Johns Hopkins University; Maryland; USA (RRID:SCR_010247) Copy
http://www.hopkins-abxguide.org/
Concise, clinically useful information for diagnosing, managing and treating infectious diseases in adults; however it does cover some pediatric topics including vaccines. It is designed for primary care providers and other non-infectious disease specialists as a tool that can be used at the point of care to assist in prescribing antibiotics.
Proper citation: ABX Guide (RRID:SCR_008214) Copy
Consortium to conduct genome-wide association studies (GWAS) to identify genes associated with an increased risk of developing late-onset Alzheimer''''s disease (LOAD). The goal of the ADGC is to identify genetic variants associated with risk for AD. It plans to do this through the following collaborative goals: # Identify genes responsible for AD susceptibility # Identify AD sub-phenotype genes rate-of-progression plaque / tangle load / distribution biomarker variability # Generate a genetic data resource for the AD research community Data generated by ADGC is available at the following website: https://www.niagads.org/content/alzheimers-disease-genetics-consortium-adgc-collection
Proper citation: Alzheimers Disease Genetics Consortium (RRID:SCR_004004) Copy
http://eaglep.case.edu/iamdgc_web/
Consortium aiming to identify the remaining genetic risk variants for Age-related Macular Degeneration (AMD). To increase the statistical power needed to identify genes that have small, yet significant contributions to AMD, the consortium is conducting a meta-analysis on 15 Genome Wide Association Studies (GWAS) pooled from consortium members representing over 8,000 patients with advanced AMD (dry type, neovascular, or both) and 50,000 controls. In addition to verifying known genes, the consortium identified 19 new gene variants. The genes identified in these studies function in the immune system, cholesterol transport and metabolism, and formation and maintenance of connective tissue. This study provides a nearly complete picture of genetic heritability for AMD.
Proper citation: International AMD Genetics Consortium (RRID:SCR_004009) Copy
National consortium of medical research institutions working together to transform the local, regional, and national environment to increase the efficiency and speed of clinical and translational research across the country. Consortium members share a common vision to reduce the time it takes for laboratory discoveries to become treatments for patients, to engage communities in clinical research efforts and to train clinical and translational researchers. This consortium includes 60 medical research institutions located throughout the nation, linking them together to energize the discipline of clinical and translational science. The CTSA consortium has five Strategic Goals: * National Clinical and Translational Research Capability * The Training and Career Development of Clinical and Translational Scientists * Consortium-Wide Collaborations * The Health of our Communities and the Nation * T1 Translational Research
Proper citation: Clinical and Translational Science Awards Consortium (RRID:SCR_008339) Copy
http://ccb.jhu.edu/software/ASprofile/
A suite of programs for extracting, quantifying and comparing alternative splicing (AS) events from RNA-seq data.
Proper citation: ASprofile (RRID:SCR_001833) Copy
http://www.bioconductor.org/packages/release/bioc/html/CoGAPS.html
Software that infers biological processes which are active in individual gene sets from corresponding microarray measurements. It achieves this inference by combining a MCMC matrix decomposition algorithm (GAPS) with a novel statistic inferring activity on gene sets.
Proper citation: CoGAPS (RRID:SCR_001479) Copy
Provides leadership in biomedical research on animal and human diseases and assists with the health and humane care of research animals within the institution.
Proper citation: Johns Hopkins School of Medicine Department of Molecular and Comparative Pathobiology (RRID:SCR_008297) Copy
http://www.nitrc.org/projects/dots/
A fast, scalable tool developed at the Johns Hopkins University to automatically segment the major anatomical fiber tracts within the human brain from clinical quality diffusion tensor MR imaging. With an atlas-based Markov Random Field representation, DOTS directly estimates the tract probabilities, bypassing tractography and associated issues. Overlapping and crossing fibers are modeled and DOTS can also handle white matter lesions. DOTS is released as a plug-in for the MIPAV software package and as a module for the JIST pipeline environment. They are therefore cross-platform and compatible with a wide variety of file formats.
Proper citation: DOTS WM tract segmentation (RRID:SCR_009459) Copy
http://sourceforge.net/projects/blox/
A quantitative medical imaging and visualization program for use on brain MR, DTI, and MRS data. Programming Language: Java, JavaScript, Scheme
Proper citation: Blox (RRID:SCR_006667) Copy
Perform clinical, epidemiological, and therapeutic research in gastroparesis and provide an infrastructure that can rapidly and efficiently design and conduct clinical trials for effective medical, surgical, or other interventions to improve treatment of patients with gastroparesis. The GpCRC studies comprise well characterized individuals with diabetic, surgical, and idiopathic gastroparesis.
Proper citation: Gastroparesis Clinical Research Consortium (RRID:SCR_006673) Copy
http://ccb.jhu.edu/software/FLASH/
Open source software tool to merge paired-end reads from next-generation sequencing experiments. Designed to merge pairs of reads when original DNA fragments are shorter than twice length of reads. Can improve genome assemblies and transcriptome assembly by merging RNA-seq data.
Proper citation: FLASH (RRID:SCR_005531) Copy
http://ccb.jhu.edu/software/glimmer/index.shtml
A software system for finding genes in microbial DNA, especially the genomes of bacteria, archaea, and viruses.
Proper citation: Glimmer (RRID:SCR_011931) Copy
http://www.scienceexchange.com/facilities/johns-hopkins-university
An Portal, Core facility
Proper citation: Johns Hopkins University Labs and Facilities (RRID:SCR_012375) Copy
http://www.nitrc.org/projects/jist/
A native Java-based imaging processing environment similar to the ITK/VTK paradigm. Initially developed as an extension to MIPAV (CIT, NIH, Bethesda, MD), the JIST processing infrastructure provides automated GUI generation for application plug-ins, graphical layout tools, and command line interfaces. This repository maintains the current multi-institutional JIST development tree and is recommended for public use and extension. JIST was originally developed at IACL and MedIC (Johns Hopkins University) and is now also supported by MASI (Vanderbilt University).
Proper citation: JIST: Java Image Science Toolkit (RRID:SCR_008887) Copy
It was created to serve as a gateway to alternatives news, information, and resources on the Internet and beyond. Altweb now is the U.S. home of the journal ALTEX: Alternatives to Animal Experimentation, which is the official publication of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT). Altweb is intended to serve: *Biomedical researchers *Industry *The international alternatives community *The international regulatory community(ies) *IACUCs and other institutional groups that review animal protocols *The animal welfare community *Individuals and groups who work with laboratory animals (technicians, veterinarians, etc.) *Educators *Students *The general public Altweb has five practical goals: 1. To assist scientists and others seeking to conduct a search for alternatives methods. 2. To serve as a CRPcentral reference pointfor alternatives information, publications, databases, calendars, and other resources. 3. To support the creation and maintenance of new alternative resources as needed, when no other organization can/will do so. 4. To promote the use of alternatives resources by publicizing them on the site and through e-mail or other outreach. 5. To facilitate communication and collaboration among members of the alternatives community, in particular those who work in database or information management.
Proper citation: Atlweb: Alternatives to Animal Testing (RRID:SCR_007265) Copy
Database that represents a centralized platform to visually depict and integrate information pertaining to domain architecture, post-translational modifications, interaction networks and disease association for each protein in the human proteome. All the information in HPRD has been manually extracted from the literature by expert biologists who read, interpret and analyze the published data.
Proper citation: HPRD - Human Protein Reference Database (RRID:SCR_007027) Copy
http://experimentalman.com/blog/
Blog about how leading-edge bio-science and technology is impacting individuals and society. This blog is an outgrowth of David Ewing Duncan''s new book, Experimental Man: What one mans body reveals about youy future, your health, and our toxic world. In the book he reports taking over 250 tests in the realms of genes, environment, brain and body and explore what these tests can tell us about one persons health, past, present, and future.
Proper citation: Experimental Man Blog (RRID:SCR_008378) Copy
Purpose of the Myc Hubsite The emergence of complex DNA microarray data on gene expression creates vast new opportunities but also poses serious challenges for information and library sciences. This complexity becomes more challenging as certain genes, such as MYC that encodes a transcription factor, switch on other genes. The purpose of this website is to provide a hub for the integration of information on Myc target genes, the role of Myc in human cancers, and proteins that interact with the Myc transcription factors. Links are provided that connect to PUBMED citations, Unigene database, and in specific cases to original data. Sponsor: Funded by a grant from the National Library of Medicine
Proper citation: MYC Cancer Gene (RRID:SCR_008608) Copy
http://ls-snp.icm.jhu.edu/ls-snp-pdb/
A web tool for genome-wide annotation of human SNPs.
Proper citation: LS-SNP/PDB (RRID:SCR_010774) Copy
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