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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
RNA-eXpress
 
Resource Report
Resource Website
1+ mentions
RNA-eXpress (RRID:SCR_005167) RNA-eXpress software resource Software designed as a user friendly solution to extract and annotate biologically important transcripts from next generation RNA sequencing data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Monash University; Melbourne; Australia
PMID:23396121 Acknowledgement requested, Non-Profit biotools:rna-express, OMICS_01285 https://bio.tools/rna-express SCR_005167 SciCrunch Registry 2026-10-24 12:45:22 5
UnoSeq
 
Resource Report
Resource Website
1+ mentions
UnoSeq (RRID:SCR_005116) UnoSeq software library, software resource, software toolkit A Java library to analyze next generation sequencing data and especially perform expression profiling in organisms where no well-annotated reference genome exists. java, expression profile, next generation sequencing is listed by: OMICtools
has parent organization: SourceForge
PMID:20194116 OMICS_01296 SCR_005116 SciCrunch Registry UnoSeq - Expression profiling with next generation sequencing without a reference genome 2026-10-24 12:45:21 1
Genomic Datasharing
 
Resource Report
Resource Website
1+ mentions
Genomic Datasharing (RRID:SCR_005233) GDS data or information resource, feed, listserv, narrative resource, standard specification NIH established expectations for sharing data obtained through NIH-funded genome-wide association studies (GWAS) with the implementation of the GWAS Policy. Information and resources related to the GWAS Policy can be found on this website. genome-wide association study, genome, data sharing is listed by: OMICtools
has parent organization: National Institutes of Health
NIH OMICS_00272 SCR_005233 SciCrunch Registry GWAS, Genome-Wide Association Studies 2026-10-24 12:45:23 5
IsoformEx
 
Resource Report
Resource Website
1+ mentions
IsoformEx (RRID:SCR_005235) software resource Software that estimates transcript expression levels and gene expression levels from mRNA-Seq data. Technically speaking, IsoformEx parses bowtie alignment files in a project directory (e.g. ~yourid/isoformex/xxx, where xxx is the project name) and generates two files: (1) xxx/xxx_transcript_1.txt: expression levels of all transcripts, (2) xxx/xxx_gene_1.txt: expression levels of all genes. is listed by: OMICtools
has parent organization: University of Pennsylvania; Philadelphia; USA
Free for academic use, Commercial use with permission OMICS_01260 SCR_005235 SciCrunch Registry IsoformEx: Isoform level gene expression estimation using non-negative least squares from mRNA-Seq data 2026-10-24 12:45:23 2
aldex
 
Resource Report
Resource Website
10+ mentions
aldex (RRID:SCR_005110) aldex software resource RNA-seq tool that uses the Dirichlet distribution and a transformation to identify genes that exhibit small within-condition and large between-condition variance. transcriptome, meta-transcriptome is listed by: OMICtools
is related to: ALDEx2
GNU General Public License, v3 OMICS_01297 SCR_005110 SciCrunch Registry aldex: ANOVA-like RNA-seq analysis 2026-10-24 12:45:21 13
ABSOLUTE
 
Resource Report
Resource Website
100+ mentions
ABSOLUTE (RRID:SCR_005198) ABSOLUTE software resource Software to estimate purity / ploidy, and from that compute absolute copy-number and mutation multiplicities. When DNA is extracted from an admixed population of cancer and normal cells, the information on absolute copy number per cancer cell is lost in the mixing. The purpose of ABSOLUTE is to re-extract these data from the mixed DNA population. This process begins by generation of segmented copy number data, which is input to the ABSOLUTE algorithm together with pre-computed models of recurrent cancer karyotypes and, optionally, allelic fraction values for somatic point mutations. The output of ABSOLUTE then provides re-extracted information on the absolute cellular copy number of local DNA segments and, for point mutations, the number of mutated alleles. is listed by: OMICtools
has parent organization: Broad Institute
Cancer, Normal PMID:22544022 Account required OMICS_00217 SCR_005198 SciCrunch Registry 2026-10-24 12:45:22 283
VARIANT
 
Resource Report
Resource Website
1000+ mentions
VARIANT (RRID:SCR_005194) VARIANT analysis service resource, data analysis service, data analysis software, data processing software, production service resource, service resource, software application, software resource Analysis tool that can report the functional properties of any variant in all the human, mouse or rat genes (and soon new model organisms will be added) and the corresponding neighborhoods. Also other non-coding extra-genic regions, such as miRNAs are included in the analysis. It not only reports the obvious functional effects in the coding regions but also analyzes noncoding SNVs situated both within the gene and in the neighborhood that could affect different regulatory motifs, splicing signals, and other structural elements. These include: Jaspar regulatory motifs, miRNA targets, splice sites, exonic splicing silencers, calculations of selective pressures on the particular polymorphic positions, etc. Software analysis pipelines used in the analysis of NGS data are highly modular, heterogeneous, and rapidly evolving. VARIANT can easily be incorporated into a NGS resequencing pipeline either as a CLI or invoked a webservice. It inputs data directly from the most widely used programs for SNV detection., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. functional property, variant, gene, non-coding region, mirna, function, single nucleotide variant, next generation sequencing, command line is listed by: OMICtools
has parent organization: Principe Felipe Research Centre; Valencia; Spain
Spanish Ministry of Science and Innovation BIO2011-27069 PMID:22693211 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00193 SCR_005194 SciCrunch Registry Variant effect, VARIant ANalysis Tool 2026-10-24 12:45:22 1366
SNPdbe
 
Resource Report
Resource Website
1+ mentions
SNPdbe (RRID:SCR_005190) SNPdbe data or information resource, data repository, database, service resource, storage service resource A database to fill the annotation gap left by the high cost of experimental testing for functional significance of protein variants. It joins related bits of knowledge, currently distributed throughout various databases, into a consistent, easily accessible, and updatable resource. It currently covers over 155,000 protein sequences which come from more than 2,600 organisms. Overall more than one million single amino acid substitutions (SAASs) are referenced consisting of natural variants, SAASs from mutagenesis experiments and sequencing conflicts. SNPdbe offers the following pieces of information (if available) on each SAAS: * Experimentally derived functional and structural impact * Predicted functional effect * Associated disease * Average heterozygosity * Experimental evidence of the nsSNP * Evolutionary conservation of wildtype and mutant amino acid * Link-outs to external databases A convenient webinterface to query SAASs on the following levels is offered: * Protein and gene identifiers and keywords * Disease keywords * Protein sequence on different sequence identity thresholds * Variant identifier (dbSNP rs, SwissVar, PMD) or specific mutant like XposY and specified sequence They offer the possibility to submit protein sequences along with experimentally substantiated mutations in order to predict their functional effect and inclusion into our database. single amino acid substitution, protein variant, protein, variant, protein sequence, natural variant, mutagenesis, sequencing, mutation is listed by: OMICtools
has parent organization: ROSTLAB
PMID:22210871 Free for academic use, Non-commercial, Commercial use with permission, The community can contribute to this resource OMICS_00185 SCR_005190 SciCrunch Registry SNPdbe - nsSNP database of functional effects, nsSNP database of functional effects 2026-10-24 12:45:22 4
qSNP
 
Resource Report
Resource Website
10+ mentions
qSNP (RRID:SCR_005105) qSNP software resource A single nucleotide variant caller optimised for identifying somatic variants in low cellularity cancer samples. is listed by: OMICtools
has parent organization: University of Queensland; Brisbane; Australia
Cancer PMID:24250782 OMICS_00089 SCR_005105 SciCrunch Registry 2026-10-24 12:45:21 26
SAMtools/BCFtools
 
Resource Report
Resource Website
1000+ mentions
SAMtools/BCFtools (RRID:SCR_005227) BCFtools software resource Provide various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format. snp, indel, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SAMTOOLS
DOI:10.1101/090811 biotools:bcftools, OMICS_13458 https://bio.tools/bcftools, https://sources.debian.org/src/bcftools/ SCR_005227 SciCrunch Registry 2026-10-24 12:45:23 1066
MiTie
 
Resource Report
Resource Website
1+ mentions
MiTie (RRID:SCR_005228) MiTie software resource Software framework for simultaneous RNA-Seq-based Transcript Identification and Quantification in Multiple Samples. They define a likelihood function based on the negative binomial distribution, use a regularization approach to select a few transcripts collectively explaining the observed read data, and show how to find the optimal solution using Mixed Integer Programming. MiTie can a) take advantage of known transcripts, b) reconstruct and quantify transcripts simultaneously in multiple samples, as well as c) resolve the location of multi-mapping reads. It is designed for genome- and assembly-based transcriptome reconstruction. c++, rna-seq, transcript is listed by: OMICtools OMICS_01279 SCR_005228 SciCrunch Registry MiTie: Simultaneous RNA-Seq-based Transcript Identification and Quantification in Multiple Samples 2026-10-24 12:45:23 4
ORMAN
 
Resource Report
Resource Website
1+ mentions
ORMAN (RRID:SCR_005188) ORMAN software resource A software tool for resolving multi-mappings within an RNA-Seq SAM file. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24130305 OMICS_01284, biotools:orman https://bio.tools/orman SCR_005188 SciCrunch Registry ORMAN : Optimal Resolution of Ambiguous RNA-Seq Multi-mappings in the Presence of Novel Isoforms 2026-10-24 12:45:22 4
FRCbam
 
Resource Report
Resource Website
10+ mentions
FRCbam (RRID:SCR_005189) software resource Software package containing tools to process bam files in order to evaluate and analyze de novo assembly / assemblers and identify Structural Variations suspicious genomics regions. The tools have been already successfully applied in several de novo and resequencing projects. This package contains two tools: # FRCbam: tool to compute Feature Response Curves in order to validate and rank assemblies and assemblers # FindTranslocations: tool to identify chromosomal rearrangements using Mate Pairs standalone software, sam, bam is listed by: OMICtools PMID:23284938 GNU General Public License, v3 OMICS_04070 SCR_005189 SciCrunch Registry 2026-10-24 12:45:22 11
SeqAnt
 
Resource Report
Resource Website
1+ mentions
SeqAnt (RRID:SCR_005186) SeqAnt analysis service resource, data analysis service, production service resource, service resource, software resource A free web service and open source software package that performs rapid, automated annotation of DNA sequence variants (single base mutations, insertions, deletions) discovered with any sequencing platform. Variant sites are characterized with respect to their functional type (Silent, Replacement, 5' UTR, 3' UTR, Intronic, Intergenic), whether they have been previously submitted to dbSNP, and their evolutionary conservation. Annotated variants can be viewed directly on the web browser, downloaded in a tab delimited text file, or directly uploaded in a Browser Extended Data (BED) format to the UCSC genome browser. SeqAnt further identifies all loci harboring two or more coding sequence variants that help investigators identify potential compound heterozygous loci within exome sequencing experiments. In total, SeqAnt resolves a significant bottleneck by allowing an investigator to rapidly prioritize the functional analysis of those variants of interest. annotation, dna sequence variant, single base mutation, insertion, deletion, sequencing, mutation, variant, sequence variant, perl, sequence, genome is listed by: OMICtools
has parent organization: Emory University; Georgia; USA
has parent organization: SourceForge
PMID:20854673 GNU General Public License, v2 OMICS_00182 SCR_005186 SciCrunch Registry SeqAnt - Sequence Annotator 2026-10-24 12:45:22 2
NGS-SNP
 
Resource Report
Resource Website
10+ mentions
NGS-SNP (RRID:SCR_005182) NGS-SNP software resource A collection of command-line scripts for providing rich annotations for SNPs identified by the sequencing of transcripts or whole genomes from organisms with reference sequences in Ensembl. Included among the annotations, several of which are not available from any existing SNP annotation tools, are the results of detailed comparisons with orthologous sequences. These comparisons allow, for example, SNPs to be sorted or filtered based on how drastically the SNP changes the score of a protein alignment. Other fields indicate the names of overlapping protein domains or features, and the conservation of both the SNP site and flanking regions. NCBI, Ensembl, and Uniprot IDs are provided for genes, transcripts, and proteins when applicable, along with Gene Ontology terms, a gene description, phenotypes linked to the gene, and an indication of whether the SNP is novel or known. A ?Model_Annotations? field provides several annotations obtained by transferring in silico the SNP to an orthologous gene, typically in a well-characterized species. annotation, snp, sequencing, transcript, genome, reference sequence, indel, annotate, reference chromosome, reference transcript, gene, command-line is listed by: OMICtools
is related to: Ensembl
has parent organization: University of Alberta; Alberta; Canada
OMICS_00177 SCR_005182 SciCrunch Registry 2026-10-24 12:45:22 33
Cancer Genomics Consortium
 
Resource Report
Resource Website
1+ mentions
Cancer Genomics Consortium (RRID:SCR_002384) CGC community building portal, data or information resource, organization portal, portal Consortium promoting communication and collaboration among cancer cytogenomics laboratories, who are interested in applying microarray technologies to cancer diagnosis and cancer research. Their oals are to (1) establish platform-neutral and cancer specific microarray designs for diagnostic purposes, (2) share cancer microarray data between participating institutions for education purposes, (3) create a public cancer array database, and (4) carry out multicenter cancer genome translational research. Collaboration amongst the different laboratories and researchers will not only provide validation for the microarray design(s) but ultimately provide more comprehensive molecular information and more accurate interpretation to better serve cancer patients and further cancer research. The CGC was officially incorporated in June 2010 as a not-for-profit organization. cytogenetics, molecular genetics, molecular pathology, microarray technology, cancer diagnosis, cancer research, microarry, cytogenomics, cancer cytogenomics, cancer genetics, genetics is listed by: OMICtools Cancer Membership fee, Account required OMICS_01776 SCR_002384 SciCrunch Registry CCMC, Cancer Cytogenomics Microarray Consortium 2026-10-24 12:44:46 6
Clinical and Laboratory Standards Institute
 
Resource Report
Resource Website
100+ mentions
Clinical and Laboratory Standards Institute (RRID:SCR_002382) CLSI data or information resource, knowledge environment, narrative resource, standard specification A not-for-profit membership organization that brings together the global laboratory community to foster excellence in laboratory medicine by facilitating the development of clinical laboratory testing standards based on input from and consensus among industry, government, and health care professionals. CLSI is setting the standard for quality in clinical laboratory testing around the world. clinical, laboratory testing, quality, clinical laboratory testing standard, laboratory, testing is listed by: OMICtools Membership fee OMICS_01777 SCR_002382 SciCrunch Registry 2026-10-24 12:44:43 195
Quick-R
 
Resource Report
Resource Website
1+ mentions
Quick-R (RRID:SCR_002417) Quick-R book, data or information resource, narrative resource, training material Training material created for both current R users, and experienced users of other statistical packages (e.g., SAS, SPSS, Stata) who would like to transition to R to help you quickly access this language in your work. The book inspired by this site takes the material here and significantly expands upon it. r, programming language, code is listed by: OMICtools Free, Available for download, Freely available OMICS_01760 SCR_002417 SciCrunch Registry Quick-R - accessing the power of R 2026-10-24 12:44:43 5
realSFS
 
Resource Report
Resource Website
10+ mentions
realSFS (RRID:SCR_002493) data analysis software, data processing software, software application, software resource Software program used to estimate allele frequency and SNP calling., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. allele frequency estimation, snp calling is listed by: OMICtools THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00071 SCR_002493 SciCrunch Registry 2026-10-24 12:44:48 27
flowBeads
 
Resource Report
Resource Website
flowBeads (RRID:SCR_002440) software resource Software package for the analysis of flow cytometry bead data. It extends flowCore to provide functionality specific to bead data. One of the goals of this package is to automate analysis of bead data for the purpose of normalization. software package, mac os x, unix/linux, windows, r, cell based assay, flow cytometry, infrastructure uses: flowCore
is listed by: OMICtools
has parent organization: Bioconductor
Free, Freely available OMICS_05592 SCR_002440 SciCrunch Registry flowBeads: Analysis of flow bead data 2026-10-24 12:44:47 0

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