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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
VAPPER
 
Resource Report
Resource Website
1+ mentions
VAPPER (RRID:SCR_016993) VAPPER data analysis software, data processing software, software application, software resource Software tool for analysis of variant antigens in African trypanosomes. Used for quantitative analysis of antigenic diversity in systems data of genomes, transcriptomes, and proteomes, called Variant Antigen Profiling to understand how antigenic diversity relates to clinical outcome, how antigen genes may be used as epidemiological markers of virulence, and in measuring gene expression during experimental infections. variant, antigen, profiling, data, genome, transcriptome, proteome, gene, expression, infection, Trypanosoma, bio.tools is listed by: Debian
is listed by: bio.tools
requires: Python Programming Language
Free, Available for download, Freely available biotools:VAPPER https://bio.tools/VAPPER SCR_016993 SciCrunch Registry VAP, VariantAntigenProfilingPER 2026-10-24 12:47:42 1
UMI-tools
 
Resource Report
Resource Website
100+ mentions
UMI-tools (RRID:SCR_017048) data analysis software, data processing software, software application, software resource Open source software package for handling Unique Molecular Identifiers in NGS data sets. unique, molecular, identifier, NGS, data, dataset, random, oligonucleotide, barcode, sequencing, copy, molecule, PCR, amplification, bio.tools is listed by: Debian
is listed by: bio.tools
Medical Research Council PMID:28100584 Free, Available for download, Freely available biotools:umi-tools https://bio.tools/umi-tools SCR_017048 SciCrunch Registry Unique Molecular Identifiers tools 2026-10-24 12:47:43 145
rnaSPAdes
 
Resource Report
Resource Website
50+ mentions
rnaSPAdes (RRID:SCR_016992) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool for assembling transcripts from RNA-Seq data. Explores surprising computational parallels between assembly of transcriptomes and single cell genomes. Suitable for all kind of organisms. Part of SPAdes package since version 3.9. assembling, transcript, RNA-Seq, data, single, cell, genome, analysis, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: SPAdes
is related to: rnaQUAST
Russian Science Foundation 14-50-00069 DOI:10.1101/420208 Free, Available for download, Freely available biotools:rnaSPAdes_autogenerated https://bio.tools/rnaSPAdes_autogenerated SCR_016992 SciCrunch Registry 2026-10-24 12:47:42 58
Goseq
 
Resource Report
Resource Website
100+ mentions
Goseq (RRID:SCR_017052) data analysis software, data processing software, software application, software resource Software application for performing Gene Ontology analysis on RNAseq data and other length biased data. Used to reduce complexity and highlight biological processes in genome wide expression studies. Gene, Ontology, analysis, RNAseq, data, sequencing, genome, expression, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
PMID:20132535 Free, Available for download, Freely available biotools:goseq https://bio.tools/goseq SCR_017052 SciCrunch Registry 2026-10-24 12:47:43 382
Genomic Ranges
 
Resource Report
Resource Website
1+ mentions
Genomic Ranges (RRID:SCR_017051) data analysis software, data processing software, software application, software resource, software toolkit Software R package for computing and annotating genomic ranges. Used for storing and manipulating genomic intervals and variables defined along genome. computing, annotating, genomic, range, storing, manipulating, interval, variable, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
NHGRI P41 HG004059;
NHGRI U41 HG004059;
NHLBI R01 HL086601;
NHLBI R01 HL093076;
NHLBI R01 HL094635
PMID:23950696 Free, Available for download, Freely available biotools:genomicranges https://bio.tools/genomicranges SCR_017051 SciCrunch Registry 2026-10-24 12:47:43 2
Salmon
 
Resource Report
Resource Website
100+ mentions
Salmon (RRID:SCR_017036) data analysis software, data processing software, software application, software resource Software tool for quantifying expression of transcripts using RNA-seq data. Provides fast and bias-aware quantification of transcript expression. Transcriptome-wide quantifier to correct for fragment GC-content bias. quantifying, expression, transcript, RNAseq, data, correct, fragment, GC, content, bias is listed by: Debian
is listed by: OMICtools
has parent organization: Stony Brook University; New York; USA
has parent organization: Carnegie Mellon University; Pennsylvania; USA
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
has parent organization: Harvard University; Cambridge; Massachusetts
Alfred P. Sloan Research ;
Gordon and Betty Moore Foundation Data-Driven Discovery Initiative ;
NCI T32 CA009337;
NHGRI R01 HG005220;
NHGRI R01 HG007104;
NHGRI R21 HG006913;
NSF BIO-1564917;
NSF CCF-1053918;
NSF CCF-1256087;
NSF EF-0849899
PMID:28263959 Free, Available for download, Freely available OMICS_09075 https://github.com/COMBINE-lab/salmon, https://sources.debian.org/src/salmon/ SCR_017036 SciCrunch Registry 2026-10-24 12:47:43 439
Bridger
 
Resource Report
Resource Website
1+ mentions
Bridger (RRID:SCR_017039) data analysis software, data processing software, software application, software resource Software package as de novo trascriptome assembler for RNA-Seq data. Framework for de novo transcriptome assembly using RNA-seq data. Can assemble all transcripts from short reads without using reference. Input RNA-Seq reads in fasta or fastq format, and ouput all assembled candidate transcripts in fasta format. Operating system Unix/Linux. de novo, transcripto, assembler, RNAseq, data, short, read, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
NCRR P20 RR016460;
NIGMS P20 GM103429;
NSFC 61272016;
NSFC 61432010
PMID:25723335 Free, Available for download, Freely available biotools:bridger, OMICS_07535 https://bio.tools/bridger SCR_017039 SciCrunch Registry 2026-10-24 12:47:43 6
betaVAEImputation
 
Resource Report
Resource Website
1+ mentions
betaVAEImputation (RRID:SCR_018730) data analysis software, data processing software, software application, software resource Software tool as deep learning framework based on variational autoencoder to impute missing values in transcriptome and methylome data analysis. Genomic data, handling missing data, deep learning framework, variational autoencoder, imputing missing values, transcriptome, methylome, data analysis, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:betavaeimputation https://bio.tools/betavaeimputation SCR_018730 SciCrunch Registry 2026-10-24 12:48:02 2
CRISPR-ERA
 
Resource Report
Resource Website
10+ mentions
CRISPR-ERA (RRID:SCR_018710) data access protocol, service resource, software resource, web service Software comprehensive design tool for CRISPR mediated gene editing, repression and activation. Fast and comprehensive guide RNA design tool for genome editing, repression and activation. Used for automated genome wide sgRNA design. Design tool, CRISPR mediated gene editing, gene repression, gene activation, guide RNA design, genome, automated genome, sgRNA design, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Stanford University; Stanford; California
FANEDD ;
NIDA R01 DA036858;
NIDCR ;
NIH Office of The Director ;
NIH Office of the Director OD017887;
NSFC
PMID:26209430 Free, Freely available biotools:CRISPR-ERA https://bio.tools/CRISPR-ERA SCR_018710 SciCrunch Registry CRISP-Editing, Repression and Activation 2026-10-24 12:48:01 13
MiXCR
 
Resource Report
Resource Website
50+ mentions
MiXCR (RRID:SCR_018725) data analysis software, data processing software, software application, software resource Software tool to processes big immunome data from raw sequences to quantitated clonotypes by MiLaboratory LLC. Universal software for analysis of T- and B-cell receptor repertoire high throughput sequencing data. Software for comprehensive adaptive immunity profiling. Process immunome data, raw sequence, quantitated clonotype, B cell receptor, sequencing data analysis, T cell receptor, high throughput sequencing data, adaptive immunity profiling, MiLaboratory, bio.tools is listed by: Debian
is listed by: bio.tools
Russian Science Foundation PMID:25924071 Restricted biotools:MiXCR, BioTools:MiXCR https://github.com/milaboratory/mixcr, https://bio.tools/MiXCR, https://bio.tools/MiXCR, https://bio.tools/MiXCR SCR_018725 SciCrunch Registry 2026-10-24 12:48:01 73
BcForms
 
Resource Report
Resource Website
BcForms (RRID:SCR_018654) data access protocol, software resource, software toolkit, web service Software toolkit for concretely describing non-canonical polymers and complexes to facilitate global biochemical networks. Web tool for describing molecular structure of macromolecular complexes, including non canonical monomeric forms, circular topologies, and crosslinks. Describes semantic meaning of whole cell computational models. Molecular structure description, molecular complex, atom, bond, protein, complex, modification, crosslinked residue, semantic meaning description, bio.tools is used by: BpForms
is used by: ObjTables
is listed by: Debian
is listed by: bio.tools
is related to: BpForms
NIBIB P41 EB023912;
NIGMS R35 GM119771;
NSF 1649014
PMID:32423472 Free, Freely available biotools:bcforms https://bio.tools/bcforms SCR_018654 SciCrunch Registry 2026-10-24 12:48:00 0
precrec
 
Resource Report
Resource Website
1+ mentions
precrec (RRID:SCR_018659) data analytics software, software application, software resource, software toolkit Software R package for fast and accurate precision recall and ROC curve calculations. Calculates accurate precision recall and Receiver Operator Characteristics curves. Precision recall, receiver operator characteristics, receiver operator characteristics curve, curve calculations, precision recall calculation, , bio.tools is listed by: Debian
is listed by: bio.tools
is related to: CRAN
DOI:10.1093/bioinformatics/btw570 Free, Freely available biotools:precrec https://bio.tools/precrec SCR_018659 SciCrunch Registry 2026-10-24 12:48:01 2
Datanator
 
Resource Report
Resource Website
1+ mentions
Datanator (RRID:SCR_018651) application programming interface, data access protocol, data or information resource, database, software resource, web application Software toolkit for discovering data needed to build, calibrate, and validate mechanistic models of cells. Integrated database of molecular data for quantitatively modeling cellular behavior. Web application for identifying relevant data for modeling specific organism in specific environmental condition. Data discovering, cell model, model cellular biochemistry, modeling specific organism, specific environmental condition, genomics, proteomics, epigenomics, metabolomics, system biology, bio.tools uses: BpForms
is listed by: Debian
is listed by: bio.tools
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
NIBIB P41 EB023912;
NIGMS R35 GM119771
DOI:10.1101/2020.08.06.240051 Free, Freely available biotools:datanator, r3d100013339 https://github.com/karrlab/datanator, https://bio.tools/datanator, https://doi.org/10.17616/R31NJMSB SCR_018651 SciCrunch Registry 2026-10-24 12:48:00 2
PrognoScan
 
Resource Report
Resource Website
100+ mentions
PrognoScan (RRID:SCR_018740) analysis service resource, data or information resource, database, production service resource, service resource Database for meta analysis of prognostic value of genes from server at Kyushu Institute of Technology. Collection of publicly available cancer microarray datasets with clinical annotation, as well as tool for assessing biological relationship between gene expression and prognosis. Provides platform for evaluating potential tumor markers and therapeutic targets. Kyushu Institute of Technology, meta analysis, prognostic gene value, cancer microarray dataset, clinical annotation, gene expression, tumor marker, therapeutic target, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
PMID:19393097 Free, Freely available SCR_018741, biotools:prognoscan http://dna00.bio.kyutech.ac.jp/PrognoScan/index.html, https://bio.tools/prognoscan SCR_018740 SciCrunch Registry 2026-10-24 12:48:02 461
Evolutionary Couplings Server
 
Resource Report
Resource Website
10+ mentions
Evolutionary Couplings Server (RRID:SCR_018745) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web server provides functional and structural information about proteins from their evolutionary record using methods from statistical physics. Computes evolutionary couplings from sequence alignments and predicts 3D structure for your protein of interest. Allows to run former EVcouplings, EVmutation, EVfold and EVcomplex jobs. Coevolutionary sequence analysis, evolutionary coupling, protein sequence, RNA sequence alignment, predict protein structure, evolutionary sequence covariantion, 3D protein structure prediction, , bio.tools is listed by: bio.tools
is listed by: Debian
DOE CSGF fellowship ;
NIGMS R01 GM106303;
NSF GRFP DGE1144152
PMID:30304492 Free, Freely available biotools:EVcouplings https://github.com/debbiemarkslab/evcouplings, https://bio.tools/EVcouplings SCR_018745 SciCrunch Registry EVcouplings 2026-10-24 12:48:02 26
StoatyDive
 
Resource Report
Resource Website
1+ mentions
StoatyDive (RRID:SCR_018796) data analysis software, data processing software, software application, software resource Software tool to evaluate and classify predicted peak profiles to assess binding specificity of protein to its targets. Can be used for sequencing data such as CLIP-seq or ChIP-Seq, or any other type of peak profile data. Evaluate predicted peak profile, classify predicted peak profile, assess binding specificity, protein-target specificity, sequencing data, CLIP-seq data, CHIP-Seq data, peak profile data, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available SCR_018800, biotools:StoatyDive https://bio.tools/StoatyDive SCR_018796 SciCrunch Registry 2026-10-24 12:48:02 1
CopyDetective
 
Resource Report
Resource Website
1+ mentions
CopyDetective (RRID:SCR_018909) algorithm resource, data analysis software, data processing software, software application, software resource Software tool for detection threshold aware CNV calling in matched whole exome sequencing data. Copy number variant calling, whole exome sequencing data, detection thresholds, deletion, duplication, case control samples, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Munster; North Rhine-Westphalia; Germany
DFG TU 298/5-1 (DFG Clinical Research Unit 326 Male Germ Cells: from Genes to Function);
DKH 111347;
DKS DKS349 2014.11 A/B (NHL-BFM Registry 2012);
EU 634789 (Horizon2020 MDS-RIGHT);
Löwenkinder - Verein zur Unterstützung krebskranker Kinder e.V.
Free, Available for download, Freely available biotools:copydetective https://bio.tools/copydetective SCR_018909 SciCrunch Registry 2026-10-24 12:48:04 1
GEMB
 
Resource Report
Resource Website
1+ mentions
GEMB (RRID:SCR_018904) data analysis software, data processing software, software application, software resource Software tool to introduce gene set enrichment for mathematical biology. Measures association between disease of interest and set of genes related to biological pathway. Used for defining gene contributions based on biophysical properties, by leveraging mathematical models of biology to predict effects of genetic perturbations on particular downstream function. Gene set enrichement, mathematical biology, disease and gene association, biophysical property, gene perturbation prediction, weighted gene set test, recover p-value, bio.tools uses: MATLAB
is listed by: bio.tools
is listed by: Debian
DOI:10.1101/554212 Free, Freely available biotools:gemb https://bio.tools/gemb SCR_018904 SciCrunch Registry Gene Set Enrichment for Mathematical Biology 2026-10-24 12:48:04 1
DicomTypeTranslator
 
Resource Report
Resource Website
1+ mentions
DicomTypeTranslator (RRID:SCR_018878) data management software, software application, software resource Open source software tool to extract metadata from DICOM files for indexing and storage in SQL database. DICOM SQL conversion, DICOM file, metadata extraction, SQL database, indexing and storage, file, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Freely available biotools:dicomtypetranslation https://bio.tools/dicomtypetranslation SCR_018878 SciCrunch Registry 2026-10-24 12:48:03 1
Batch Web CD-Search Tool
 
Resource Report
Resource Website
500+ mentions
Batch Web CD-Search Tool (RRID:SCR_018756) data access protocol, service resource, software resource, web service Web tool for detection of structural and functional domains in protein sequences. Allows computation and download of conserved domain annotation for large sets of protein queries. Allows to view results graphically. Shows domain footprints, alignment details, and conserved features on any individual query sequence. Functional domain detection, protein sequence, protein sequence domain, functional domain, protein, nucleotide sequence, conserved domain search, bio.tools is listed by: Debian
is listed by: bio.tools
NIH Intramural Research Program PMID:15215404 Free, Freely available biotools:cd-search https://bio.tools/cd-search SCR_018756 SciCrunch Registry NCBI Batch CD Search Tool, Batch conserved domain search, Conserved Domain Search service, CD-search 2026-10-24 12:48:02 838

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