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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
System for long term volumetric imaging of living cells. Makes light sheet fluorescence microscopy available for live cell imaging at subcellular resolution. Automated system for volumetric imaging of subcellular structures and dynamics over hours and days with protection from photo damage.
Proper citation: Zeiss: Lattice Lightsheet 7 (RRID:SCR_021237) Copy
https://diagnostics.roche.com/us/en/products/instruments/discovery-ultra-research.html
Immunohistochemistry processor that can be used for immunohistochemistry and in situ hybridization slide preparation and processing. With 30 individual slide drawers, DISCOVERY ULTRA system enables to run both manual and fully automated experiments simultaneously with nosynchronization errors. Provides ability to fully automate broad range of IHC and ISH assays, including FISH, gene and protein IHC/ISH, mRNA ISH and multiplex assays with any combination of IHC and ISH.
Proper citation: Roche: Ventana DISCOVERY Ultra (RRID:SCR_021254) Copy
Benchtop genetic analyzer. Electrophoresis system for DNA and RNA sample quality control. It can be used for next generation sequencing or Biobank workflow.
Proper citation: Agilent: 4200 TapeStation System (RRID:SCR_018435) Copy
http://tools.thermofisher.com/content/sfs/manuals/cms_040970.pdf
Automated PCR instrument for automated amplification of nucleic acids with Polymerase Chain Reaction. It has reaction volumes of up to 50 uL and sample temperature range of 4 to 99.9 C.
Proper citation: Thermo Fisher: Applied Biosystems: GeneAmp 9700 PCR Thermocycler System (RRID:SCR_018436) Copy
https://www.ohsu.edu/pharmacokinetics-core
Core for analysis of drugs and their metabolites and bio-molecules such as simple peptides, oligonucleotides, carbohydrates, lipids, fatty acids and steroids. Provides open access to laboratory where users prepare and analyze their own samples by HPLC, GC/MS or LC/MS on equipment maintained by core personnel. Provides analysis of samples including development of analytical methods, sample preparation, and data analysis for clinical trials as well as basic science investigations.
Proper citation: OHSU Bioanalytical Shared Resource Pharmacokinetics Core Facility (RRID:SCR_009963) Copy
https://www.ohsu.edu/advanced-imaging-research-center/about-advanced-imaging-research-center
Provides magnetic resonance instruments including Siemens 3 Tesla Prisma, Siemens Magnetom 7 Tesla, and Bruker 11.75 Tesla to support research investigating normal physiology, brain development and aging, and disease pathophysiology with high performance non invasive imaging capabilities.
Proper citation: OHSU Advanced Imaging Research Center Core Facility (RRID:SCR_009960) Copy
https://www.ohsu.edu/octri/clinical-and-translational-research-center
Provides nursing, bionutrition, study coordination, and laboratory services and support. Laboratory is designed and equipped to perform both basic and specialized research assays and sample processing in support of translational research studies and trials. Laboratory staff have extensive experience in performance of wide variety of analytical and genetic based assays and procedures.
Proper citation: OHSU Oregon Clinical and Translational Research Center Core Facility (RRID:SCR_009996) Copy
https://www.ohsu.edu/proteomics-shared-resource
Core facility that provides the following services: Protein identification and partial sequencing, Determination of whole protein mass, Targeted SRM analysis of known proteins, Protein quantitation assay, Gel electrophoresis. The OHSU Protemics Shared Resource facility was established to make state-of-the-art mass spectrometry based protein analysis analytical capabilities available to the biomedical research community at OHSU.
Proper citation: OHSU Proteomics Shared Resource Core Facility (RRID:SCR_009991) Copy
https://www.ohsu.edu/medicinal-chemistry-core/nmr
Core facility that provides the following services: NMR instrument training. A facility that uses a state-of-the-art NMR spectrometer to verify or determine the structure of organic molecules. Housed in the Department of Physiology and Pharmacology, it is designed to exploit the power of designed small molecules as probes of protein and cellular function and to provide the foundation for the development of prototypic therapeutic agents.
Proper citation: OHSU Nuclear Magnetic Resonance Core Facility (RRID:SCR_009989) Copy
https://www.ohsu.edu/transgenic-mouse-models-core
Core assists investigators with developing genetically engineered rodent models of human diseases for studying mutant genes and investigating molecular mechanisms underlying pathological processes.
Proper citation: OHSU Animal Model Support Core Facility (RRID:SCR_009994) Copy
Florida State University is a public research university in Tallahassee, Florida, United States. It is a senior member of the State University System of Florida and a preeminent university in the state. Chartered in 1851, it is located on Florida's oldest continuous site of higher education.
Proper citation: Florida State University; Florida; USA (RRID:SCR_011228) Copy
https://moffitt.org/research-science/shared-resources/molecular-genomics/
Molecular Genomics Core Facility at Moffitt Cancer Center in Tampa, FL offers services to assess gene expression, epigenetic modification and sequence variation. Performs bulk and single cell RNA and DNA sequencing on Illumina platform, NanoString nCounter, GeneChip and Illumina array services.Offers services to discuss your project and timeline for your project.
Proper citation: Moffitt Cancer Center Molecular Genomics Core Facility (RRID:SCR_012333) Copy
https://www.cores.emory.edu/rbc/
One of the Emory Integrated Core Facilities (EICF), is supported by Emory University School of Medicine and the Georgia Clinical and Translational Science Alliance. We plan, execute, and analyze behavioral experiments examining activity, arousal, coordinated movement, learning and memory, anxiety, depression, seizure susceptibility, reward/reinforcement, and aggression in mice and rats.
Proper citation: Emory University Rodent Behavioral Core (RRID:SCR_012499) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/mspcf/index.html
MSPCF maintains and uses equipment for protein separation and imaging, as well as for sample preparation for mass spectrometry analysis. Offers range of bioinformatics tools for data mining and evaluation. Services include Protein Identification, Protein Interactome Analysis, Protein Post-translational Modifications, Quantitative Mass Spectrometry, Molecular Weight determination.
Proper citation: University of Nebraska Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_012539) Copy
https://cbc.arizona.edu/research/support-services/facilities/nuclear-magnetic-resonance-nmr
Interdisciplinary NMR spectroscopy research facility for structural elucidation and study of conformation and dynamics of organic compounds, peptides, oligonucleotides and other small biopolymers.
Proper citation: University of Arizona Nuclear Magnetic Resonance Core Facility (RRID:SCR_012716) Copy
https://www.sbpdiscovery.org/biomedical-research/shared-resources/cancer-metabolism
Facility that aims to investigate role of metabolism in cancer on cellular and organismal level, combining in vitro and in vivo analysis. Comprehensive metabolic facility, including stable isotope tracing and flux analysis. Provides analysis of metabolism using specialist instruments and methodologies, together with advice on planning experiments and analyzing data. All instruments and approaches are available on fee-for-service basis to Cancer Center scientists, but alsoto outside users. Samples for most services can be shipped, but Seahorse analyzer users need to be local so they can bring live cells for analysis.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Cancer Metabolism Core Facility (RRID:SCR_014873) Copy
http://www.scripps.edu/florida/technologies/cbs/index.html
Core facility that provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes. Services include cell lines, hit-picking clones and various screening sets, and access to equipment.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.
Proper citation: Scripps Research Institute Florida Cell Based High Throughput Screening Core Facility (RRID:SCR_014877) Copy
Genomics and transcriptomics core at the UCD Genome Center provides high throughput sequencing, genotyping, single-cell multi-omics and spatial transcriptomics services, training and consultation. Initial consultations are free. The lab uses liquid handling robots to minimize sample handling variation and to provide fast turnaround times.
Proper citation: University of California Davis DNA Technologies and Expression Analysis Core Facility (RRID:SCR_017740) Copy
https://web.uri.edu/riinbre/mic/
Core provides sequencing and bioinformatics support for INBRE and non-INBRE researchers. Provides data science services adjacent to traditional bioinformatics; access to computational and software resources for INBRE network institutions, particularly primarily undergraduate institutions; training for students and faculty in data science methods. Maintains professional network with other core and user facilities in Rhode Island and beyond to maximize resources available to our users.Utilizes novel technologies such as virtual/augmented reality for use in teaching and research.
Proper citation: Rhode Island INBRE Molecular Informatics Core Facility (RRID:SCR_017685) Copy
https://core.bioinformatics.udel.edu
CBCB Bioinformatics Data Science Core builds upon infrastructure of the Center for Bioinformatics and Computational Biology. Delaware Biotechnology Institute , Delaware Data Science Institute, and Protein Information Resource. Core helps with planning your research or analyzing your current data. Services:Consultation and Collaboration, Proposal Assistance,Training, Bioinformatics Software, Computational Hardware, Database and Web Services, Next Gen Analysis, Custom Analysis.
Proper citation: University of Delaware CBCB Bioinformatics Data Science Core Facility (RRID:SCR_017696) Copy
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