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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
casper
 
Resource Report
Resource Website
100+ mentions
casper (RRID:SCR_006613) casper software resource Software to infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 or greater biotools:casper, OMICS_01270 https://bio.tools/casper SCR_006613 SciCrunch Registry casper - Characterization of Alternative Splicing based on Paired-End Reads, Characterization of Alternative Splicing based on Paired-End Reads 2026-10-17 01:26:39 152
ChIPXpress
 
Resource Report
Resource Website
1+ mentions
ChIPXpress (RRID:SCR_006653) ChIPXpress software resource A R package designed to improve ChIP-seq and ChIP-chip target gene ranking using publicly available gene expression data. It takes as input predicted transcription factor (TF) bound genes from ChIPx data and uses a corresponding database of gene expression profiles downloaded from NCBI GEO to rank the TF bound targets in order of which gene is most likely to be functional TF target. gene expression, chip-seq, chip-chip, transcription factor, target gene, gene, gene expression profile is listed by: OMICtools
is related to: Gene Expression Omnibus
has parent organization: Bioconductor
GNU General Public License, v2 or greater OMICS_00516 SCR_006653 SciCrunch Registry ChIPXpress: enhanced transcription factor target gene identification from ChIP-seq and ChIP-chip data using publicly available gene expression profiles 2026-10-17 01:26:39 2
EDASeq
 
Resource Report
Resource Website
100+ mentions
EDASeq (RRID:SCR_006751) EDASeq software resource Software for numerical and graphical summaries of RNA-Seq read data. Within-lane normalization procedures to adjust for GC-content effect (or other gene-level effects) on read counts: loess robust local regression, global-scaling, and full-quantile normalization (Risso et al., 2011). Between-lane normalization procedures to adjust for distributional differences between lanes (e.g., sequencing depth): global-scaling and full-quantile normalization (Bullard et al., 2010)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. data analysis, normalization, rna-seq is listed by: OMICtools
has parent organization: Bioconductor
has parent organization: National Cancer Institute
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01231 SCR_006751 SciCrunch Registry EDASeq: Exploratory Data Analysis and Normalization for RNA-Seq data 2026-10-17 01:26:41 255
ShortRead
 
Resource Report
Resource Website
100+ mentions
ShortRead (RRID:SCR_006813) ShortRead software resource Software package for input, quality assessment and exploration of high-throughput sequence data. Used for input, quality assurance, and basic manipulation of `short read'' DNA sequences such as those produced by Solexa, 454, and related technologies, including exible import of common short read data formats. high throughput sequence data, short read, DNA sequences, short read data is listed by: OMICtools
is listed by: Debian
is listed by: SoftCite
has parent organization: Bioconductor
PMID:19654119 Free, Available for download, Freely available OMICS_01076 https://sources.debian.org/src/r-bioc-shortread/ SCR_006813 SciCrunch Registry ShortRead - Classes and methods for high-throughput short-read sequencing data. 2026-10-17 01:26:43 235
RIPSeeker
 
Resource Report
Resource Website
10+ mentions
RIPSeeker (RRID:SCR_006810) RIPSeeker software resource A statistical software package for identifying protein-associated transcripts from RIP-seq experiments. Infer and discriminate RIP peaks from RIP-seq alignments using two-state HMM with negative binomial emission probability. While RIPSeeker is specifically tailored for RIP-seq data analysis, it also provides a suite of bioinformatics tools integrated within this self-contained software package comprehensively addressing issues ranging from post-alignments processing to visualization and annotation. rip-seq is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v2 OMICS_00569 SCR_006810 SciCrunch Registry RIPSeeker: a statistical package for identifying protein-associated transcripts from RIP-seq experiments 2026-10-17 01:26:47 12
RamiGO
 
Resource Report
Resource Website
10+ mentions
RamiGO (RRID:SCR_006922) RamiGO software resource Software package with an R interface sending requests to AmiGO visualize, retrieving DAG GO trees, parsing GraphViz DOT format files and exporting GML files for Cytoscape. Also uses RCytoscape to interactively display AmiGO trees in Cytoscape. visualization, analysis, ontology or annotation search engine, ontology or annotation visualization, other analysis, classification, go, graph, network, third party client, windows, mac os x, linux, unix, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: Cytoscape
is related to: AmiGO
has parent organization: Dana-Farber Cancer Institute
has parent organization: Bioconductor
PMID:23297033 Artistic License, v2 biotools:ramigo, OMICS_02267, nlx_149331 http://bioconductor.org/packages/release/bioc/html/RamiGO.html, https://bio.tools/ramigo SCR_006922 SciCrunch Registry ramigo, RamiGO - AmiGO visualize R interface 2026-10-17 01:26:48 12
Gene Ontology Tools
 
Resource Report
Resource Website
10+ mentions
Gene Ontology Tools (RRID:SCR_006941) GO Tools catalog, data or information resource, database, software repository, software resource Collection of tools developed by GO Consortium and by third parties. Tools are listed by category or alphabetically and continue to be improved and expanded. registry, annotation browser, annotation search engine, annotation visualization, ontology, annotation editor, database, data warehouse, software library, statistical analysis, slimmer-type tool, term enrichment, text mining, protein interaction, functional similarity, semantic similarity, analysis, annotation, visualization, editor lists: GOALIE
lists: GenNav
lists: High-Throughput GoMiner
lists: Onto-Design
lists: Avadis
lists: GONUTS
lists: PiNGO
lists: TM4 Microarray Software Suite - TIGR MultiExperiment Viewer
lists: FunSimMat
lists: BioPerl
lists: Database for Annotation Visualization and Integrated Discovery
lists: GOToolBox Functional Investigation of Gene Datasets
lists: StRAnGER
lists: Short Time-series Expression Miner (STEM)
lists: GORetriever
lists: Gene Ontology Browsing Utility (GOBU)
lists: GeneTools
lists: GOSlimViewer
lists: go-moose
lists: Network Ontology Analysis
lists: OBO-Edit
lists: Onto-Compare
lists: Onto-Express
lists: OntoVisT
lists: STRAP
lists: CGAP GO Browser
lists: COBrA
lists: Gene Class Expression
lists: GeneInfoViz
lists: GOfetcher
lists: GoFish
lists: GOProfiler
lists: GOanna
lists: Manatee
lists: Pandora - Protein ANnotation Diagram ORiented Analysis
lists: TAIR Keyword Browser
lists: Wandora
lists: GeneMANIA
lists: GOTaxExplorer
lists: go-db-perl
lists: Onto-Miner
lists: Onto-Translate
lists: ToppGene Suite
lists: DBD - Slim Gene Ontology
lists: go-perl
lists: ONTO-PERL
lists: OWLTools
lists: Blip: Biomedical Logic Programming
lists: OWL API
lists: CLENCH
lists: BiNGO: A Biological Networks Gene Ontology tool
lists: CateGOrizer
lists: FuSSiMeG: Functional Semantic Similarity Measure between Gene-Products
lists: ProteInOn
lists: GeneMerge
lists: GraphWeb
lists: ClueGO
lists: CLASSIFI - Cluster Assignment for Biological Inference
lists: GOHyperGAll
lists: FuncAssociate: The Gene Set Functionator
lists: GOdist
lists: FuncExpression
lists: FunCluster
lists: FIVA - Functional Information Viewer and Analyzer
lists: GARBAN
lists: GOEx - Gene Ontology Explorer
lists: SGD Gene Ontology Slim Mapper
lists: GOArray
lists: GoSurfer
lists: GOtcha
lists: MAPPFinder
lists: GoAnnotator
lists: MetaGeneProfiler
lists: OntoGate
lists: ProfCom - Profiling of complex functionality
lists: SerbGO
lists: SOURCE
lists: Ontologizer
lists: THEA - Tools for High-throughput Experiments Analysis
lists: Generic GO Term Mapper
lists: GREAT: Genomic Regions Enrichment of Annotations Tool
lists: GoBean - a Java application for Gene Ontology enrichment analysis
lists: TXTGate
lists: GO-Module
lists: IT-GOM: Integrated Tool for IC-based GO Semantic Similarity Measures
lists: G-SESAME - Gene Semantic Similarity Analysis and Measurement Tools
lists: Expression Profiler
lists: GOChase
lists: Whatizit
lists: REViGO
lists: WEGO - Web Gene Ontology Annotation Plot
lists: Blast2GO
lists: InterProScan
lists: PubSearch
lists: GO Online SQL Environment (GOOSE)
lists: Gene Ontology For Functional Analysis (GOFFA)
lists: MGI GO Browser
lists: GOEAST - Gene Ontology Enrichment Analysis Software Toolkit
lists: Ontology Lookup Service
lists: WebGestalt: WEB-based GEne SeT AnaLysis Toolkit
lists: g:Profiler
lists: OwlSim
lists: GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool
lists: FastSemSim
lists: RamiGO
lists: GeneCodis
lists: FunSpec
lists: FunNet - Transcriptional Networks Analysis
lists: agriGO
lists: GOblet
lists: DynGO
lists: SeqExpress
lists: ProbeExplorer
lists: GOstat
lists: Onto-Express To Go (OE2GO)
lists: Tk-GO
lists: Spotfire
lists: GOMO - Gene Ontology for Motifs
lists: GFINDer: Genome Function INtegrated Discoverer
lists: Agile Protein Interactomes DataServer
lists: elk-reasoner
lists: Flash Gviewer
lists: L2L Microarray Analysis Tool
lists: OnEx - Ontology Evolution Explorer
lists: Semantic Measures Library
lists: AmiGO
lists: Babelomics
lists: T-profiler
lists: QuickGO
lists: FSST - Functional Similarity Search Tool
lists: GoPubMed
lists: Bioconductor
lists: ErmineJ
lists: Comparative Toxicogenomics Database (CTD)
lists: LexGrid
lists: Candidate Genes to Inherited Diseases
lists: EGAN: Exploratory Gene Association Networks
lists: Generic GO Term Finder
lists: Integrated Manually Extracted Annotation
lists: EASE: the Expression Analysis Systematic Explorer
is listed by: NIF Data Federation
has parent organization: Gene Ontology
Free, Freely available nlx_146273 https://neuinfo.org/mynif/search.php?q=*&t=indexable&nif=nlx_146273-1 http://www.geneontology.org/GO.tools.shtml SCR_006941 SciCrunch Registry 2026-10-17 01:26:49 27
ggtree
 
Resource Report
Resource Website
50+ mentions
ggtree (RRID:SCR_018560) data processing software, data visualization software, software application, software resource Software R package for visualization and annotation of phylogenetic trees with their covariates and other tree like structures with their annotation data. Can import evolutionary data from different tree file formats and analysis programs as well as other associated data from experiments so that various sources and types of data can be displayed on tree for comparison and further analyses. Phylogenetic tree visualization, phylogenetic tree annotation, data, bio.tools is listed by: CRAN
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
Seed Funding Programme for Basic Research DOI:10.1111/2041-210X.12628 Free, Available for download, Freely available biotools:ggtree https://bio.tools/ggtree SCR_018560 SciCrunch Registry 2026-10-17 01:29:42 61
minet
 
Resource Report
Resource Website
minet (RRID:SCR_018661) data analysis software, data processing software, network analysis software, software application, software resource, software toolkit Open source software R package for inferring large transcriptional networks using mutual information. Implements algorithms for inferring networks such as gene networks from microarray data. Inferring transcriptional network, mutual information, gene network, microarray data, gene, statistical dependencies model, gene to gene interaciton, statistical quantification, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Bioconductor
has parent organization: Free University of Brussels; Brussels; Belgium
Communaute Francaise de Belgique PMID:18959772 Free, Available for download, Freely available biotools:minet http://minet.meyerp.com/, https://bio.tools/minet SCR_018661 SciCrunch Registry Mutual Information NETworks 2026-10-17 01:29:35 0
scTHI
 
Resource Report
Resource Website
1+ mentions
scTHI (RRID:SCR_018918) scTHI data analysis software, data processing software, software application, software resource Software R package to identify active pairs of ligand receptors from single cells in order to study,among others, tumor host interactions. Contains set of signatures to classify cells from tumor microenvironment. Ligand receptor, active pair, active pair ligand receptor, single cell, tumor interaction, tumor microenvironment, cells clasification is listed by: Bioconductor Free, Available for download, Freely available SCR_018918 SciCrunch Registry 2026-10-17 01:29:32 1
variancePartition
 
Resource Report
Resource Website
50+ mentions
variancePartition (RRID:SCR_019204) data analysis software, data analytics software, data processing software, software application, software resource Software R package to quantify and interpret divers of variation in multilevel gene expression experiments.Provides statistical and visualization framework for studying drivers of variation in RNA-seq datasets in many types of high throughput genomic assays including RNA-seq gene-, exon- and isoform-level quantification, splicing efficiency, protein quantification, metabolite quantification, metagenomic assays, methylation arrays and epigenomic sequencing assays. Repeated measures, variation in gene expression, RNA-seq datasets, high throughput genomic assays, splicing efficiency, protein quantification, metabolite quantification, metagenomic assays, methylation arrays, epigenomic sequencing assays, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is related to: CRAN
Icahn School of Medicine at Mount Sinai ;
NHLBI U01 HL107388
PMID:27884101 Free, Available for download, Freely available biotools:variancepartition https://bio.tools/variancepartition SCR_019204 SciCrunch Registry 2026-10-17 01:29:35 62
SynergyFinder
 
Resource Report
Resource Website
500+ mentions
SynergyFinder (RRID:SCR_019318) data processing software, data visualization software, software application, software resource, software toolkit Software R package as efficient implementations for all popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of synergy scores as either two dimensional or three dimensional interaction surface over dose matrix. Used to calculate and visualize synergy scores for drug combinations. Synergy scores, drug combinations, popular synergy scoring models, dimensional interaction surface, dose matrix, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is related to: SynergyFinder web application
DOI:10.1007/978-1-4939-7493-1_17 Free, Available for download, Freely available biotools:synergyfinder https://bio.tools/synergyfinder SCR_019318 SciCrunch Registry synergyfinder 2026-10-17 01:29:37 624
Repitools
 
Resource Report
Resource Website
10+ mentions
Repitools (RRID:SCR_013242) Repitools software resource Software tools for the analysis of enrichment-based epigenomic data. is listed by: OMICtools
has parent organization: Bioconductor
OMICS_00619 SCR_013242 SciCrunch Registry 2026-10-17 01:28:41 22
CancerMutationAnalysis
 
Resource Report
Resource Website
CancerMutationAnalysis (RRID:SCR_013181) CancerMutationAnalysis software resource Software package that implements gene and gene-set level analysis methods for somatic mutation studies of cancer. is listed by: OMICtools
has parent organization: Bioconductor
Cancer OMICS_00141 SCR_013181 SciCrunch Registry 2026-10-17 01:28:41 0
MSstats
 
Resource Report
Resource Website
100+ mentions
MSstats (RRID:SCR_014353) data analysis software, data processing software, software application, software resource A package for statistical relative quantification of proteins and peptides in global, targeted, and data-independent proteomics. It handles shotgun, label-free, and label-based Selected Reaction Monitoring, as well as SWATH/DIA (Data Independent Acquisition) experiments. MSStats provide functionality for data processing and visualization, model-based statistical analysis, and model-based sample size calculations. data independent acquisition, statistical relative quantification, protein, peptide, data analysis software, data processing, data visualization, proteomics uses: R Project for Statistical Computing
is used by: Skyline
is listed by: Bioconductor
National Science Foundation CAREER award 1054826 DOI:10.1186/1471-2105-13-S16-S6 Acknowledgement requested, Available for download http://www.bioconductor.org/packages/release/bioc/html/MSstats.html SCR_014353 SciCrunch Registry MSStats 2026-10-17 01:28:46 239
MetaCyto
 
Resource Report
Resource Website
1+ mentions
MetaCyto (RRID:SCR_016415) data analysis software, data processing software, software application, software resource, software toolkit Software tool for automated meta-analysis of mass and flow cytometry data. Provides functions for preprocessing, automated gating and meta-analysis of cytometry data and collection of cytometry data from the ImmPort database. automated, analysis, meta, flow, cytometry, data, bio.tools is listed by: Bioconductor
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
is related to: The Immunology Database and Analysis Portal (ImmPort)
the National Institute of Allergy and Infectious Diseases HHSN272201200028C Free, Available for download, Freely available biotools:metacyto https://bio.tools/metacyto SCR_016415 SciCrunch Registry 2026-10-17 01:29:12 5
RnaSeqGeneEdgeRQL
 
Resource Report
Resource Website
RnaSeqGeneEdgeRQL (RRID:SCR_016699) data analysis software, data processing software, software application, software resource, software toolkit Software to study analysis of an RNA-Seq experiment using the Rsubread and edgeR packages. The workflow starts from read alignment and continues on to data exploration, to differential expression and, finally, to pathway analysis. The analysis includes plots, GO and KEGG analyses, and the analysis of a expression signature as generated by a prior experiment. study, analysis, RNA, sequencing, read, alignment, data is affiliated with: Bioconductor Free, Available for download, Freely available SCR_016699 SciCrunch Registry 2026-10-17 01:29:09 0
clusterProfiler
 
Resource Report
Resource Website
10000+ mentions
clusterProfiler (RRID:SCR_016884) data analysis software, data processing software, data visualization software, software application, software resource Software R package for statistical analysis and visualization of functional profiles for genes and gene clusters. data, statistical, analysis, visualization, gene, cluster, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
2007 Chang-Jiang Scholars Program ;
Fundamental Research Funds for the Central Universities ;
Guangdong Natural Science Research Grant ;
National 973 Projects of China ;
National Natural Science Foundation of China
PMID:22455463 Free, Available for download, Freely available biotools:clusterprofiler https://github.com/GuangchuangYu/clusterProfiler, https://guangchuangyu.github.io/software/clusterProfiler/, https://bio.tools/clusterprofiler SCR_016884 SciCrunch Registry Cluster Profiler 2026-10-17 01:29:18 13465
CATALYST
 
Resource Report
Resource Website
100+ mentions
CATALYST (RRID:SCR_017127) data analysis software, data processing software, software application, software resource, software toolkit Software R package to provide pipeline for preprocessing of cytometry data, including normalization using bead standards, single cell deconvolution, and bead based compensation. preprocessing, cytometry, data, normalization, bead, standard, single, cell, deconvulsion, compensation, bio.tools uses: CATALYSTLite
is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
European Research Council ;
NIDDK UC4 DK108132;
PhosphonetPPM and MetastasiX SystemsX grant ;
Roche Postdoctoral Fellowship ;
SNSF Assistant Professorship grant ;
Swiss National Science Foundation
PMID:29605184 Free, Available for download, Freely available biotools:catalyst https://github.com/HelenaLC/CATALYST, https://bio.tools/catalyst SCR_017127 SciCrunch Registry Cytometry dATa anALYSis Tools 2026-10-17 01:29:14 241
GAGE
 
Resource Report
Resource Website
50+ mentions
GAGE (RRID:SCR_017067) data analysis software, data processing software, software application, software resource Software R package for gene set enrichment or pathway analysis. Applicable independent of microarray or RNAseq data attributes including sample sizes, experimental designs, assay platforms, and other types of heterogeneity. Pipeline routines of multiple GAGE analyses in batch, comparison between parallel analyses, and combined analysis of heterogeneous data from different sources and studies. gene, set, enrichment, pathway, batch, comparison, parallel, analysis, heterogeneous, data is listed by: Bioconductor
is related to: R Project for Statistical Computing
Free, Available for download, Freely available SCR_017067 SciCrunch Registry Generally Applicable Gene-set Enrichment for pathway analysis, gage, Generally Applicable Gene-set Enrichment, GSEA 2026-10-17 01:29:12 53

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