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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Oak Ridge Collection at JAX
 
Resource Report
Resource Website
Oak Ridge Collection at JAX (RRID:SCR_016409) ORNL, ORC biomaterial supply resource, material resource, organism supplier Supplier of mice for research purposes. mouse, strain, supply, research, repository, subject, genetic engineering, knockout, mice, gene, model is listed by: International Mouse Strain Resource SCR_016409 Oak Ridge Collection, Oak Ridge Laboratory, JAX Oak Ridge, Oak Ridge Lab, Oakridge, The Oak Ridge National Laboratory (ORNL), Oak Ridge National Laboratory, Oak Ridge 2026-09-12 12:58:39 0
Oriental BioService Inc.
 
Resource Report
Resource Website
1+ mentions
Oriental BioService Inc. (RRID:SCR_016404) OBS biomaterial supply resource, material resource, organism supplier Supplier of mice for research purposes. mouse, strain, supply, research, repository, subject, genetic engineering, knockout, mice, gene, model, transgenic is listed by: International Mouse Strain Resource SCR_016404 Oriental BioService, Oriental BioServices 2026-09-12 12:58:39 8
Monocle2
 
Resource Report
Resource Website
100+ mentions
Monocle2 (RRID:SCR_016339) data analysis software, data processing software, software application, software resource, software toolkit Software package for analyzing single cell gene expression, classifying and counting cells, performing differential expression analysis between subpopulations of cells, and reconstructing cellular trajcectories. Works well with very large single-cell RNA-Seq experiments containing tens of thousands of cells or more. Used in computational analysis of gene expression data in single cell gene expression studies to profile transcriptional regulation in complex biological processes and highly heterogeneous cell populations. analysis, heterogenous, population, single, cell, gene, expression, data, large, single-cell RNA-Seq, transcriptional, regulation, heterogen Alfred P. Sloan Foundation Research Fellowship ;
NIH DP2 HD088158
PMID:24658644 Free, Available for download, Freely available SCR_016339 Monocle 2 2026-09-12 12:58:38 227
GEO2R
 
Resource Report
Resource Website
50+ mentions
GEO2R (RRID:SCR_016569) data analysis software, data processing software, software application, software resource Software as an interactive web tool to compare two or more groups of samples in a Gene Expression Omnibus (GEO) series regardless of data type and quality. Used to identify genes that are differentially expressed across experimental conditions. Results are presented as a table of genes ordered by significance. compare, group, sample, gene, expression, omnibus, data, identify, differentially, expressed, across, condition, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Bioconductor
is related to: GEOquery
is related to: LIMMA
Free, Available for download, Freely available biotools:GEO2R https://bio.tools/GEO2R SCR_016569 2026-09-12 12:58:41 76
AbundantOTU+
 
Resource Report
Resource Website
1+ mentions
AbundantOTU+ (RRID:SCR_016527) AbundantOTU data analysis software, data processing software, sequence analysis software, software application, software resource Software tool for analysis of large 16S rRNA pyrosequences by using a consensus alignment algorithm, utilizing the sequence redundancy of abundant species in the pyrosequence dataset. pyrosequencing, 16S, rRNA, gene, operational, taxonomic, unit, abundant, species, dataset is listed by: OMICtools
has parent organization: Indiana University; Indiana; USA
NHGRI R01 HG004908;
NHLBI U01 HL09896001
PMID:22102981 Free, Available for download, Freely available SCR_016527 AbundantOTU:Abundant Operational Taxonomic Unit, Abundant OTU, AbundantOTU+ 2026-09-12 12:58:40 1
TRANSIT
 
Resource Report
Resource Website
1+ mentions
TRANSIT (RRID:SCR_016492) data analysis software, data processing software, software application, software resource Software tool Python based and open source for statistical analysis of TnSeq data. Provides a graphical interface to three different statistical methods for analyzing TnSeq data capable of identifying essential genes in individual datasets as well as comparative analysis between conditions. statistical, analysis, TnSeq, data, identify, gene, dataset, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Texas A and M University; Texas; USA
PMID:26447887 Free, Available for download, Freely available biotools:transit https://github.com/mad-lab/transit, https://bio.tools/transit SCR_016492 2026-09-12 12:58:40 4
Transcriptome Analysis Console
 
Resource Report
Resource Website
10+ mentions
Transcriptome Analysis Console (RRID:SCR_016519) TAC data analysis software, data processing software, sequence analysis software, software application, software resource Software tool for microarray analysis designed for biologists . Used for identification of differential expression by providing interactive visualizations. transcriptome, analysis, console, data, array, gene, visualization, identify Commercially available SCR_016519 TAC:Transcriptome Analysis Console 2026-09-12 12:58:40 21
Generalized Relevance Network
 
Resource Report
Resource Website
1+ mentions
Generalized Relevance Network (RRID:SCR_016488) GenRelNet data analysis software, data processing software, network analysis software, software application, software resource Software tool with approaching infers network structure by measuring the pairwise associations between the data observed in the individual network nodes. It follows the more general statistical perspective of GRN inference, where no explicit model of the data is built or assumed. network, inference, reconstruction, relevance, approach, gene, regulatory Free, Available for download, Freely available SCR_016488 GenRelNet:Generalized Relevance Network 2026-09-12 12:58:40 1
CODEHOP
 
Resource Report
Resource Website
50+ mentions
CODEHOP (RRID:SCR_002898) CODEHOP analysis service resource, data analysis service, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone.Service to design PCR primers from protein multiple sequence alignments. NOTICE: This version of CODEHOP is no longer maintained. degenerate, primer, primer design, degenerate primer, oligonucleotide, pcr assay, gene, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Fred Hutchinson Cancer Center
PMID:20967601 THIS RESOURCE IS NO LONGER IN SERVICE biotools:codehop, OMICS_02339 https://bio.tools/codehop SCR_002898 COnsensus-DEgenerate Hybrid Oligonucleotide Primers, CODEHOP: COnsensus-DEgenerate Hybrid Oligonucleotide Primers 2026-09-12 01:01:27 75
Ligand-Gated Ion Channel Database
 
Resource Report
Resource Website
1+ mentions
Ligand-Gated Ion Channel Database (RRID:SCR_002418) LGICdb data or information resource, database Database providing access to information about transmembrane proteins that exist under different conformations, with three primary subfamilies: the cys-loop superfamily, the ATP gated channels superfamily, and the glutamate activated cationic channels superfamily. Due to the lack of evolutionary relationship, these three superfamilies are treated separately. It currently contains 554 entries of ligand-activated ion channel subunits. In this database one may find: the nucleic and proteic sequences of the subunits. Multiple sequence alignments can be generated, and some phylogenetic studies of the superfamilies are provided. Additionally, the atomic coordinates of subunits, or portion of subunits, are provided when available. Redundancy is kept to a minimum, i.e. one entry per gene. Each entry in the database has been manually constructed and checked by a researcher of the field in order to reduce the inaccuracies to a minimum. NOTE: This database is not actively maintained anymore. People should not consider it as an up-to-date trustable resource. For any new work, they should consider using alternative sources, such as UniProt, Ensembl, Protein Databank etc. equilibrium, extracellular, gabaa, gated, gene, genetics, 3d model, alignment, anionic, atomic, atp, cationic, cellular, molecular, channel, compartment, computation, conformation, coordinate, cys-loop, glutamate, glycine, histamine, homologous, ion, ion channel, ligand, membrane, nicotinic, nucleic acid, phylogenetic, pore, portion, proteic, nucleic acid, protein, phylogeny, receptor, segment, sequence, sequence data, serotonin, subunit, superfamily, transmembrane is listed by: re3data.org
has parent organization: European Bioinformatics Institute
College of France; Paris; France ;
Centre National de la Recherche Scientifique ;
European Union ;
Biotech and Biomed contracts ;
French Ministry of Higher Education and Research ;
Institut Pasteur
PMID:16381861
PMID:11125117
nif-0000-00037, r3d100010796 https://doi.org/10.17616/R3Q90D SCR_002418 LGIC Database 2026-09-12 01:01:25 1
GeneCards
 
Resource Report
Resource Website
5000+ mentions
GeneCards (RRID:SCR_002773) GeneCards data or information resource, database Database of human genes that provides concise genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted human genes. Information featured in GeneCards includes orthologies, disease relationships, mutations and SNPs, gene expression, gene function, pathways, protein-protein interactions, related drugs and compounds and direct links to cutting edge research reagents and tools such as antibodies, recombinant proteins, clones, expression assays and RNAi reagents. genome, human gene, genome, gene, genomic, proteomic, transcriptomic, genetic, function, ortholog, disease, mutation, single nucleotide polymorphism, gene expression, gene function, pathway, protein-protein interaction, drug, compound, reagent, antibody, recombinant protein, clone, expression assay, rnai reagent, FASEB list is listed by: OMICtools
is related to: MOPED - Model Organism Protein Expression Database
PMID:20689021 Free, Freely available nif-0000-02879, OMICS_01652, r3d100012015 http://bioinfo.weizmann.ac.il/genecards/, https://doi.org/10.17616/R3D643 SCR_002773 GeneCards - The Human Gene Compendium 2026-09-12 01:01:26 7635
HomoloGene
 
Resource Report
Resource Website
100+ mentions
HomoloGene (RRID:SCR_002924) HomoloGene data or information resource, database, service resource Automated system for constructing putative homology groups from complete gene sets of wide range of eukaryotic species. Databse that provides system for automatic detection of homologs, including paralogs and orthologs, among annotated genes of sequenced eukaryotic genomes. HomoloGene processing uses proteins from input organisms to compare and sequence homologs, mapping back to corresponding DNA sequences. Reports include homology and phenotype information drawn from Online Mendelian Inheritance in Man, Mouse Genome Informatics, Zebrafish Information Network, Saccharomyces Genome Database and FlyBase. homolog, paralog, ortholog, genome, gene, protein, protein alignment, phenotype, conserved domain, homology, amino acid sequence, cell, dna, gold standard is used by: NIF Data Federation
is used by: Nowomics
is used by: MitoMiner
is listed by: OMICtools
is listed by: re3data.org
is related to: OMIM
is related to: Mouse Genome Informatics (MGI)
is related to: Zebrafish Information Network (ZFIN)
is related to: SGD
is related to: FlyBase
is related to: ProbeMatchDB 2.0
is related to: Biomine
is related to: Consensus CDS
has parent organization: NCBI
PMID:23193264 Free, Freely availalbe nif-0000-02975, r3d100010781, OMICS_01544 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=homologene, https://doi.org/10.17616/R3889F SCR_002924 NCBI HomoloGene 2026-09-12 01:01:27 459
Zebrafish Information Network (ZFIN)
 
Resource Report
Resource Website
500+ mentions
Zebrafish Information Network (ZFIN) (RRID:SCR_002560) ZFIN data or information resource, database Model organism database that serves as central repository and web-based resource for zebrafish genetic, genomic, phenotypic and developmental data. Data represented are derived from three primary sources: curation of zebrafish publications, individual research laboratories and collaborations with bioinformatics organizations. Data formats include text, images and graphical representations.Serves as primary community database resource for laboratory use of zebrafish. Developed and supports integrated zebrafish genetic, genomic, developmental and physiological information and link this information extensively to corresponding data in other model organism and human databases. expression, gene, anatomy, development, disease, genomic, model, molecular, mutant, neuronal, organism, phenotype, physiological, synteny, zebrafish, gene expression, genome sequence, molecular neuroanatomy resource, genotype, anatomical structure, publication, genome, image collection, gold standard, bio.tools, FASEB list, RRID Community Authority uses: InterMOD
is used by: NIF Data Federation
is used by: Resource Identification Portal
is used by: Morpholino Database
is used by: Integrated Animals
is used by: NIH Heal Project
is recommended by: Resource Identification Portal
is recommended by: NIDDK Information Network (dkNET)
is recommended by: National Library of Medicine
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: OMICtools
is listed by: InterMOD
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: AmiGO
is related to: Phenoscape Knowledgebase
is related to: MONARCH Initiative
is related to: Bgee: dataBase for Gene Expression Evolution
is related to: NIH Data Sharing Repositories
is related to: HomoloGene
is related to: Zebrafish International Resource Center
is related to: Integrated Manually Extracted Annotation
is related to: Zebrafish Genome Project
has parent organization: University of Oregon; Oregon; USA
is parent organization of: ZFIN Antibody Database
is parent organization of: Zebrafish Anatomical Ontology
is parent organization of: ZFIN Protocol Wiki
is parent organization of: ZFIN Antibody Wiki
is organization facet of: Alliance of Genome Resources
NHGRI P41 HG002659;
NHGRI R01 HG004834
PMID:23074187
PMID:21036866
PMID:16381936
Free, Available for download, Freely available OMICS_01666, nif-0000-21427, biotools:zfin, r3d100010421, SCR_017504 http://zfin.org/ZFIN/misc_html/tips.html#newrecord, https://wiki.zfin.org/display/general/ZFIN+Data+Submissions, https://bio.tools/zfin, https://doi.org/10.17616/R3CK5Z SCR_002560 Zebrafish Database, The Zebrafish Model Organism Database, Zebra Model Organism Database, ZebraFish Information Network, ZFIN 2026-09-12 01:01:26 978
Knowledgebase for Addiction Related Genes
 
Resource Report
Resource Website
1+ mentions
Knowledgebase for Addiction Related Genes (RRID:SCR_002687) KARG data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 14,2026. Database of data and knowledge linking genes and chromosome regions to addiction that were extracted from reviewing more than 1,000 peer-reviewed publications from between 1976 and 2006. This list of publications included review papers on addiction selected from results of PUBMED query "(addiction OR drug abuse) AND review" as well as research papers selected from PUBMED query "(addiction OR drug abuse) AND (gene OR microarray OR proteomics OR QTL OR population association OR genetic linkage)". The data spanned multiple technology platforms including classical hypothesis-testing of single genes, identification of significantly differentially expressed genes in microarray experiments, identification of significantly differentially expressed proteins in proteomics assays, identification of addiction-vulnerable chromosome regions in animal QTL studies, genetic linkage studies, population association studies, and OMIM annotations. From each publication they collected the genes, proteins, or chromosome regions linked to addiction, as well as metadata such as species, nature of the addictive substance, studied brain regions, technology platforms, and experimental parameters. In total, they collected 2,343 items of evidence linking 1,500 human genes to addiction. Among them 396 genes were supported by two or more items of evidence. The interface supports browsing of the genes by chromosome or pathways, advanced text search by gene ID, organism, type of addictive substance, technology platform, protein domain, and/or PUBMED ID, and sequence search by BLAST similarity. All data, database schema, and MySQL commands are freely available for download. molecular neuroanatomy resource, gwas, meta-analysis, genetic susceptibility, gene, protein, chromosome, pathway, drug of abuse, blast, addiction, substance abuse, drug abuse, microarray, proteomics, qtl, population association, genetic linkage uses: PubMed
has parent organization: Peking University; Beijing; China
PMID:18179280 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00411 SCR_002687 KARG: Knowledgebase for Addiction-Related Gene, Knowledgebase for Addiction-Related Gene, KARG: Knowledgebase for Addiction Related Genes 2026-09-12 01:01:26 8
EcoGene
 
Resource Report
Resource Website
50+ mentions
EcoGene (RRID:SCR_002437) ECK, ECOGENE, ECOGENE G data or information resource, database Database that contains updated information about the Escherichia coli K-12 genome and proteome sequences, including extensive gene bibliographies. Users are able to download customized tables, perform Boolean query comparisons, generate sets of paired DNA sequences, and download any E. coli K-12 genomic DNA sub-sequence. BLAST functions, microarray data, an alphabetical index of genes, and gene overlap queries are also available. The Database Table Downloads Page provides a full list of EG numbers cross-referenced to the new cross-database ECK numbers and other common accession numbers, as well as gene names and synonyms. Monthly release archival downloads are available, but the live, daily updated version of EcoGene is the default mysql database for download queries. life sciences, genomics, proteomics, gene, gene expression, genetics, protein, protein binding, protein-protein interaction, membrane, rna, dna, structure, function, functional annotation, annotation, blast, FASEB list is listed by: re3data.org
is related to: RefSeq
is related to: Colibri
has parent organization: University of Miami Miller School of Medicine; Florida; USA
NIH ;
Lucille P. Markey Foundation ;
NIGMS 5-R01-GM58560-05
PMID:23197660
PMID:10592181
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02784, r3d100010546 https://doi.org/10.17616/R3KP5V http://bmb.med.miami.edu/ http://bmb.med.miami.edu/EcoGene/EcoWeb/ http://www.ecogene.org/old/ SCR_002437 EcoGene Database of Escherichia coli Sequence and Function 2026-09-12 01:01:25 58
object-oriented Transcription Factors Database
 
Resource Report
Resource Website
1+ mentions
object-oriented Transcription Factors Database (RRID:SCR_002435) data or information resource, database ooTFD (object-oriented Transcription Factors Database) is a successor to TFD, the original Transcription Factors Database. This database is aimed at capturing information regarding the polypeptide interactions which comprise and define the properties of transcription factors. ooTFD contains information about transcription factor binding sites, as well as composite relationships within transcription factors, which frequently occur as multisubunit proteins that form a complex interface to cellular processes outside the transcription machinery through protein-protein interactions. ooTFD contains information represented in TFD but also allows the representation of containment, composite, and interaction relationships between transcription factor polypeptides. It is designed to represent information about all transcription factors, both eukaryotic and prokaryotic, basal as well as regulatory factors, and multiprotein complexes as well as monomers. eukaryotic, expression, factor, gene, basal, binding site, biochemical, biology, cellular, complex, genome, genomic, information, interaction, molecule, monomer, multisubunit, nucleotide sequences, transcriptional regulator sites, transcription factors, object, polypeptide, process, prokaryotic, property, protein, protein-protein interaction, regulatory, sequence, transcription has parent organization: IFTI-Mirage PMID:10592257
PMID:9847215
PMID:9399874
Free, Freely available nif-0000-21303 SCR_002435 ooTFD 2026-09-12 01:01:25 2
Database oDatabase of Predicted Subcellular Localization for Eukaryotic PDB Chainsf Predicted Subcellular Localization for Eukaryotic PDB Chains
 
Resource Report
Resource Website
Database oDatabase of Predicted Subcellular Localization for Eukaryotic PDB Chainsf Predicted Subcellular Localization for Eukaryotic PDB Chains (RRID:SCR_002831) data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. LOC3d is a database of predicted subcellular localization for eukaryotic proteins of known 3-D structure taken from the Protein Databank. Subcellular localization is currently predicted using four different methods: predictNLS (nuclear localization signal), LOChom (using homology), LOCkey (using keywords) and LOC3d (neural network based prediction). The reported localization is based on the method which predicts localization of a given protein with the highest confidence. LOCtree is a novel system of support vector machines (SVMs) that predict the subcellular localization of proteins, and DNA-binding propensity for nuclear proteins, by incorporating a hierarchical ontology of localization classes modeled onto biological processing pathways. Biological similarities are incorporated from the description of cellular components provided by the gene ontology consortium (GO). GO definitions have been simplified and tailored to the problem of protein sorting. Technically the ontology has been implemented using a decision tree with SVMs as the nodes. LOCtree, was extremely successful at learning evolutionary similarities among subcellular localization classes and was significantly more accurate than other traditional networks at predicting subcellular localization. Whenever available, LOCtree also reports predictions based on the following: 1) Nuclear localization signals found by PredictNLS, 2) Localization inferred using Prosite motifs and Pfam domains found in the protein, and 3) SWISS-PROT keywords associated with a protein. Localization is inferred in the last two cases using the entropy-based LOCkey algorithm. Additional information can be found in the LOCtree manuscript and associated PredictNLS and LOCkey publications. eukaryotic, gene, binding, biological, dna, localization, nuclear, pathway, protein, structure, subcellular, vector, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Columbia University; New York; USA
PMID:12824321 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-25200, biotools:loc3d https://bio.tools/loc3d SCR_002831 LOC3d 2026-09-12 01:01:26 0
Exonic Splicing Enhancer Finder
 
Resource Report
Resource Website
50+ mentions
Exonic Splicing Enhancer Finder (RRID:SCR_002835) analysis service resource, data analysis service, production service resource, service resource A web-based analysis service for identifying exonic splicing enhancers in eukaryotic genes. ESEfinder accept sequences in the FASTA format. A typical mammalian gene is composed of several relatively short exons that are interrupted by much longer introns. To generate correct mature mRNAs, the exons must be identified and joined together precisely and efficiently, in a process that requires the coordinated action of five small nuclear (sn)RNAs (U1, U2, U4, U5 and U6) and more than 60 polypeptides. The inaccurate recognition of exon/intron boundaries or the failure to remove an intron generates aberrant mRNAs that are either unstable or code for defective or deleterious protein isoforms. Exonic enhancers are thought to serve as binding sites for specific serine/arginine-rich (SR) proteins, a family of structurally related and highly conserved splicing factors characterized by one or two RNA-recognition motifs (RRM) and by a distinctive C-terminal domain highly enriched in RS dipeptides (the RS domain). The RRMs mediate sequence-specific binding to the RNA, and so determine substrate specificity, whereas the RS domain appears to be involved mainly in protein-protein interactions. SR proteins bound to ESEs can promote exon definition by directly recruiting the splicing machinery through their RS domain and/or by antagonizing the action of nearby silencer elements. Sponsors: ESEfinder is supported by the Cold Spring Harbor Laboratory. element, enhancer, eukaryotic, exon, exonic, gene, analysis, arginine, boundary, c-terminal, dipeptide, intron, isoform, mammalian, mrna, nuclear, polypeptide, protein, recognition, rna, serine, service, snrna, splice has parent organization: Cold Spring Harbor Laboratory Free, Freely available nif-0000-25204 SCR_002835 ESEfinder 2026-09-12 01:01:26 66
ABS: A Database of Annotated Regulatory Binding Sites From Orthologous Promoters
 
Resource Report
Resource Website
1+ mentions
ABS: A Database of Annotated Regulatory Binding Sites From Orthologous Promoters (RRID:SCR_002276) ABS data or information resource, database Public database of known binding sites identified in promoters of orthologous vertebrate genes that have been manually curated from bibliography. We have annotated 650 experimental binding sites from 68 transcription factors and 100 orthologous target genes in human, mouse, rat or chicken genome sequences. Computational predictions and promoter alignment information are also provided for each entry. For each gene, TFBSs conserved in orthologous sequences from at least two different species must be available. Promoter sequences as well as the original GenBank or RefSeq entries are additionally supplied in case of future identification conflicts. The final TSS annotation has been refined using the database dbTSS. Up to this release, 500 bps upstream the annotated transcription start site (TSS) according to REFSEQ annotations have been always extracted to form the collection of promoter sequences from human, mouse, rat and chicken. For each regulatory site, the position, the motif and the sequence in which the site is present are available in a simple format. Cross-references to EntrezGene, PubMed and RefSeq are also provided for each annotation. Apart from the experimental promoter annotations, predictions by popular collections of weight matrices are also provided for each promoter sequence. In addition, global and local alignments and graphical dotplots are also available. gene, alignment, annotation, binding, computational, genome, nucleotide, ortholog, prediction, promoter, sequence, target, transcription, transcriptional factor, binding site, promoter sequence, protein motif, benchmark, transcription factor binding site, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: IntegromeDB
has parent organization: Center for Genomic Regulation; Barcelona; Spain
European Union FP6 contract LSHG-CT-2003-503265 PMID:16381947 Acknowledgement requested, GNU General Public License, v2 biotools:alggen, nif-0000-21006 https://bio.tools/alggen SCR_002276 A database of Annotated regulatory Binding Sites from orthologous promoters 2026-09-12 01:01:25 3
T3DB
 
Resource Report
Resource Website
10+ mentions
T3DB (RRID:SCR_002672) T3DB data or information resource, database Database that combines detailed toxin data with comprehensive toxin target information. The database currently houses 3,053 toxins described by 32,276 synonyms, including pollutants, pesticides, drugs, and food toxins, which are linked to 1,670 corresponding toxin target records. Altogether there are 37,084 toxin, toxin target associations. (March 2014) Each toxin record (ToxCard) contains over 50 data fields and holds information such as chemical properties and descriptors, toxicity values, molecular and cellular interactions, and medical information. This information has been extracted from over 5,454 sources sources, which include other databases, government documents, books, and scientific literature. The focus of the T3DB is on providing mechanisms of toxicity and target proteins for each toxin. This dual nature of the T3DB, in which toxin and toxin target records are interactively linked in both directions, makes it unique from existing databases. It is also fully searchable and supports extensive text, sequence, chemical structure, and relational query searches toxicology, toxin, pollutant, pesticide, drug, food, gene-drug, interaction, gene, phenotype, mechanism, bio.tools is used by: NIF Data Federation
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: FMA
has parent organization: University of Alberta; Alberta; Canada
Alberta Advanced Education and Technology ;
Canadian Institutes of Health Research ;
Genome Alberta ;
Genome Canada
PMID:19897546 Free, Available for download, Freely available r3d100012189, nif-0000-22933, biotools:t3db, OMICS_01592 https://bio.tools/t3db, https://doi.org/10.17616/R3VM0R SCR_002672 Toxin-Target Database, Toxin Toxin-Target Database, Toxin and Toxin Target Database, Toxin, Toxin Toxin Target Database 2026-09-12 01:01:26 27

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