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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
Aroma.affymetrix
 
Resource Report
Resource Website
10+ mentions
Aroma.affymetrix (RRID:SCR_010919) Aroma.affymetrix software resource An R package for analyzing large Affymetrix data sets. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
OMICS_00703, biotools:aroma.affymetrix https://bio.tools/aroma.affymetrix SCR_010919 SciCrunch Registry 2026-10-10 12:38:40 34
kmer-SVM
 
Resource Report
Resource Website
1+ mentions
kmer-SVM (RRID:SCR_010882) kmer-SVM analysis service resource, data analysis service, production service resource, service resource, software resource A webserver built on the Galaxy framework that enables the mining of sequence data for transcription factor binding sites. This tool suite was designed to aid in analysis of next-generation sequencing (NGS) data that uses a support vector machine (SVM) with kmer sequence features to identify predictive combinations of short transcription factor binding sites which determine the tissue specificity of the original NGS assay. While you may use datasets already available from Galaxy, you can upload your data using the ''Get Data'' Tool. The tool can upload data from a variety of locations. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Johns Hopkins University School of Medicine; Baltimore, Maryland; USA
has parent organization: Galaxy
PMID:23771147 Acknowledgement requested OMICS_00484, biotools:kmer-svm https://bio.tools/kmer-svm SCR_010882 SciCrunch Registry 2026-10-10 12:38:20 3
NURD
 
Resource Report
Resource Website
50+ mentions
NURD (RRID:SCR_010988) NURD software resource An algorithm to inference isoform expression., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:nurd, OMICS_01283 https://bio.tools/nurd SCR_010988 SciCrunch Registry 2026-10-10 12:38:42 72
Gene3D
 
Resource Report
Resource Website
100+ mentions
Gene3D (RRID:SCR_007672) Gene3D data access protocol, data or information resource, data repository, database, service resource, software resource, storage service resource, web service A large database of CATH protein domain assignments for ENSEMBL genomes and Uniprot sequences. Gene3D is a resource of form studying proteins and the component domains. Gene3D takes CATH domains from Protein Databank (PDB) structures and assigns them to the millions of protein sequences with no PDB structures using Hidden Markov models. Assigning a CATH superfamily to a region of a protein sequence gives information on the gross 3D structure of that region of the protein. CATH superfamilies have a limited set of functions and so the domain assignment provides some functional insights. Furthermore most proteins have several different domains in a specific order, so looking for proteins with a similar domain organization provides further functional insights. Strict confidence cut-offs are used to ensure the reliability of the domain assignments. Gene3D imports functional information from sources such as UNIPROT, and KEGG. They also import experimental datasets on request to help researchers integrate there data with the corpus of the literature. The website allows users to view descriptions for both single proteins and genes and large protein sets, such as superfamilies or genomes. Subsets can then be selected for detailed investigation or associated functions and interactions can be used to expand explorations to new proteins. The Gene3D web services provide programmatic access to the CATH-Gene3D annotation resources and in-house software tools. These services include Gene3DScan for identifying structural domains within protein sequences, access to pre-calculated annotations for the major sequence databases, and linked functional annotation from UniProt, GO and KEGG., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. protein domain, protein, protein superfamily, hidden markov model, structural domain, genome, sequence, domain assignments, protein structure, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: University College London; London; United Kingdom
NIH ;
Wellcome Trust ;
European Union FP6 ENFIN LSHG-CT-2003-503265;
European Union FP6 ENFIN LSHG-CT-2004-512092;
European Union FP6 ENFIN LSHG-CT-2005-518254;
DOE DE-AC02-065CH11357
PMID:19906693
PMID:18032434
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02877, biotools:gene3d https://bio.tools/gene3d SCR_007672 SciCrunch Registry Gene3D - Structures assigned to Genomes 2026-10-10 12:37:51 272
AmpliconNoise
 
Resource Report
Resource Website
50+ mentions
AmpliconNoise (RRID:SCR_007814) AmpliconNoise software resource A collection of programs for the removal of noise from 454 sequenced PCR amplicons. This project also includes the Perseus algorithm for chimera removal. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
DOI:10.1186/1471-2105-12-38 biotools:pyronoise, OMICS_01112 https://bio.tools/pyronoise, https://sources.debian.org/src/anfo/ SCR_007814 SciCrunch Registry 2026-10-10 12:37:55 91
ALTree
 
Resource Report
Resource Website
1+ mentions
ALTree (RRID:SCR_007562) data analysis software, data processing software, software application, software resource Software package to perform phylogeny based association and localization analysis.Used for association detection and localization of susceptibility sites using haplotype phylogenetic trees. Performs these two phylogeny-based analysis: tests association between candidate gene and disease; pinpoints markers (SNPs) that are putative disease susceptibility loci. phylogeny based association, association detection, susceptibility sites, haplotype phylogenetic trees, gene, genetic, genomic is listed by: Genetic Analysis Software
is listed by: Debian
PMID:16595555
DOI:10.1093/bioinformatics/btl131
Free, Available for download, Freely available OMICS_13032, nlx_154221 https://sources.debian.org/src/altree/, https://gitlab.inria.fr/NGS/ALTree, SCR_007562 SciCrunch Registry ALTREE 2026-10-10 12:37:54 3
Gene Expression Atlas
 
Resource Report
Resource Website
100+ mentions
Gene Expression Atlas (RRID:SCR_007989) atlas, data or information resource, database, expression atlas Gene Expression Atlas is a semantically enriched database of meta-analysis based summary statistics over a curated subset of ArrayExpress Archive, servicing queries for condition-specific gene expression patterns as well as broader exploratory searches for biologically interesting genes/samples. The EBI Gene Expression Atlas Blog discusses ideas, features and problems of creating a large scale meta-analytical atlas of gene expression from publicly available microarray data. Atlas REST API provides all the results available in the main web application in a pragmatic, easy to use form - simple HTTP GET queries as input and either JSON or XML formats as output. Gene Expression Atlas goals: 1. Provision of a statistically robust framework for integration of gene expression experiment results across different platforms at a meta-analytical level 2. A simple interface for identifying strong differential expression candidate genes in conditions of interest 3. Integration of ontologies for high quality annotation of gene and sample attributes 4. Construction of new gene expression summarized views, with a view to analysis of putative signaling pathway targets, discovery of correlated gene expression patterns and the identification of condition/tissue-specific patterns of gene expression. expression, gene, annotation, assay, molecular neuroanatomy resource, gold standard, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: ArrayExpress
is related to: Experimental Factor Ontology
has parent organization: European Bioinformatics Institute
EMBL ;
European Union FELICS ;
European Union EMERALD
nif-0000-06686, biotools:gxa_expt, r3d100010223, biotools:gene_expression_atlas https://bio.tools/gxa_expt, https://bio.tools/gene_expression_atlas, https://doi.org/10.17616/R3Z888 SCR_007989 SciCrunch Registry 2026-10-10 12:37:53 132
Variant Effect Predictor
 
Resource Report
Resource Website
1000+ mentions
Variant Effect Predictor (RRID:SCR_007931) VEP analysis service resource, data analysis service, production service resource, service resource, software resource Data analysis service to predict the functional consequences of known and unknown variants. perl, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Ensembl
biotools:ensembl_variant_effect_predictor https://bio.tools/ensembl_variant_effect_predictor SCR_007931 SciCrunch Registry Ve!P 2026-10-10 12:37:54 2073
eTBlast
 
Resource Report
Resource Website
1+ mentions
eTBlast (RRID:SCR_008188) eTBlast data or information resource, database, narrative resource, service resource eTBLAST is a unique search engine for searching biomedical literature. Our service is very different from PubMed. While PubMed searches for keywords, our search engine lets you input an entire paragraph and returns MEDLINE abstracts that are similar to it. This is something like PubMed''s Related Articles feature, only better because it runs on your unique set of interests. For example, input the abstract of an unpublished paper or a grant proposal into our engine, and with the touch of a button you''ll be able to find every abstract in MEDLINE dealing with your topic. No more guessing whether your set of keywords has found all the right papers. No more sorting through hundreds of papers you don''t care about to find the handful you were looking for--our search engine does it for you. When most people use PubMed to search MEDLINE they pick one or two keywords to describe their topic, then browse through a long list of results. When they find a paper that looks interesting they click on its Related Articles, in hopes of finding more papers like that one. If they find another relevant paper, they explore it''s related articles--and so on. This process of culling long lists of documents by hand makes literature searching tedious and time consuming. We make it easier for you by providing better results the first time, and then allowing you to automatically combine the papers you care about for a second round. Our Iterate feature allows you to checkmark the abstracts you found interesting in the first round and combine them all to create a new query. It''s like rolling several Related Articles lists into one. * We sort our results by relevance, while PubMed sorts by date. * We save you the time and effort of creating a complicated query. * We let you iterate your search over several good papers to narrow your focus. * We provide you the full MEDLINE abstract in our results, and a link to the PubMed page. * We can send your results straight to your email so you never lose a reference or forget where you found it. * This absolutely free service is provided by the University of Texas Southwestern Medical Center. No registration necessary! biomedical, literature, medline interfaces, paper, publish, search engine, unpublished, journal, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Texas Southwestern Medical Center; Texas; USA
has parent organization: Virginia Polytechnic Institute and State University; Virginia; USA
Hudson Foundation ;
P.O'B. Montgomery Distinguished Chair
PMID:16926219 biotools:etblast, nif-0000-21148 https://bio.tools/etblast http://invention.swmed.edu/etblast/index.shtml SCR_008188 SciCrunch Registry eTBLAST: a text-similarity based search engine 2026-10-10 12:37:55 5
Network Analysis, Visualization and Graphing TORonto
 
Resource Report
Resource Website
50+ mentions
Network Analysis, Visualization and Graphing TORonto (RRID:SCR_008373) NAViGaTOR d visualization software, data processing software, data visualization software, software application, software resource A software package for visualizing and analyzing protein-protein interaction networks. NAViGaTOR can query OPHID / I2D - online databases of interaction data - and display networks in 2D or 3D. To improve scalability and performance, NAViGaTOR combines Java with OpenGL to provide a 2D/3D visualization system on multiple hardware platforms. NAViGaTOR also provides analytical capabilities and supports standard import and export formats such as GO and the Proteomics Standards Initiative (PSI). NAViGaTOR can be installed and run on Microsoft Windows, Linux / UNIX, and Mac OS systems. NAViGaTOR is written in Java and uses JOGL (Java bindings for OpenGL) to support scalability, highlighting or suppressing of information, and other advanced graphic approaches. fly, algorithm, capacity, graphical, graphing, human, interaction, interactome, intersection, mouse, network, node, protein, proteomic, rat, worm, yeast, graphing application, 2d visualization, 3d visualization, visualization, biological network, protein-protein interaction, gene, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Toronto; Ontario; Canada
Genome Canada ;
Ontario Genomics Institute ;
Canada Research Chair Program ;
Ontario Research Fund Research Excellence ;
Canada Foundation for Innovation 12301;
Canada Foundation for Innovation 203383
PMID:19837718 Freely-downloadable for academic and not-for-profit institutions nif-0000-25610, biotools:navigator https://bio.tools/navigator SCR_008373 SciCrunch Registry NAViGaTOR - Network Analysis Visualization and Graphing TORonto, NAViGaTOR - Network Analysis Visualization & Graphing TORonto 2026-10-10 12:38:19 55
EMBOSS
 
Resource Report
Resource Website
1000+ mentions
EMBOSS (RRID:SCR_008493) EMBOSS data analysis software, data processing software, sequence analysis software, software application, software resource, software toolkit Software analysis package for molecular biology community. Automatically copes with data in variety of formats and allows transparent retrieval of sequence data from web. Libraries are provided with package. Provides toolkit for creating bioinformatics applications or workflows. Provides set of sequence analysis programs. Provided programs cover areas such as sequence alignment, rapid database searching with sequence patterns, protein motif identification, nucleotide sequence pattern analysis, codon usage analysis for small genomes, rapid identification of sequence patterns in large scale sequence sets, and presentation tools for publication. FASEB list is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
is related to: BioExtract
is related to: pepwheel
DOI:10.1016/S0168-9525(00)02024-2 Free, Freely available OMICS_21165, nif-0000-30488 https://sources.debian.org/src/emboss/ http://www.emboss.org SCR_008493 SciCrunch Registry The European Molecular Biology Open Software Suite, European Molecular Biology Open Software Suite 2026-10-10 12:38:05 4742
Vienna RNA
 
Resource Report
Resource Website
100+ mentions
Vienna RNA (RRID:SCR_008550) data or information resource, database, software resource This server provides programs, web services, and databases, related to our work on RNA secondary structures. For general information and other offerings from our group see the main TBI web server. With the 1st of May 2009 we updated our servers to the Vienna RNA package version 1.8.2! The Vienna RNA Servers: * RNAfold server predicts minimum free energy structures and base pair probabilities from single RNA or DNA sequences. * RNAalifold server predicts consensus secondary structures from an alignment of several related RNA or DNA sequences. You need to upload an alignment. * RNAinverse server allows you to design RNA sequences for any desired target secondary structure. * RNAcofold server allows you to predict the secondary structure of a dimer. * RNAup server allows you to predict the accessibility of a target region. * LocARNA server generates structural alignments from a set of sequences. In collaboration with the Bioinformatics Group Freiburg. * barriers server allows you to get insights into RNA folding kinetics. * RNAz server will assist you in detecting thermodynamically stable and evolutionarily conserved RNA secondary structures in multiple sequence alignments. * Structure conservation analysis server will assist you in detecting evolutionarily conserved RNA secondary structures in multiple sequence alignments. * RNAstrand server allows you to predict the reading direction of evolutionarily conserved RNA secondary structures. * RNAxs server assists you in siRNA design. * Bcheck predicts rnpB genes Downloads Get the Source code for: * the Vienna RNA Package, our basic RNA secondary structure analysis software. * The ALIDOT package for finding conserved structure motifs (add-on) * The barriers program for analysis of RNA folding landscapes. Databases * Atlas of conserved Viral RNA Structures found by ALIDOT bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: ANNOgesic
has parent organization: University of Vienna; Vienna; Austria
DOI:10.1186/1748-7188-6-26 biotools:vienna_rna_package, nif-0000-31411, OMICS_09351 https://bio.tools/vienna_rna_package, https://sources.debian.org/src/vienna-rna/ SCR_008550 SciCrunch Registry Vienna RNA 2026-10-10 12:38:00 425
tRNAscan-SE
 
Resource Report
Resource Website
1000+ mentions
tRNAscan-SE (RRID:SCR_008637) analysis service resource, data analysis service, production service resource, service resource, software resource, web application Web server to search for tRNA genes in genomic sequence. If you would like to run tRNAscan-SE locally, you can get the UNIX source code (gzip''d tar file). bio.tools, tRNA genes, genomic sequence is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
has parent organization: University of California at Santa Cruz; California; USA
PMID:15980563
PMID:9023104
DOI:10.1093/nar/25.5.0955
Free, Freely available SCR_010835, OMICS_00385, nif-0000-32031, biotools:trnascan-se https://bio.tools/trnascan-se, https://sources.debian.org/src/trnascan-se/ SCR_008637 SciCrunch Registry Lowe Lab tRNAscan-SE 2026-10-10 12:38:21 2855
STEPS
 
Resource Report
Resource Website
100+ mentions
STEPS (RRID:SCR_008742) STEPS simulation software, software application, software resource STEPS is a package for exact stochastic simulation of reaction-diffusion systems in realistic, complex 3D geometries. Our core simulation algorithm is an efficient implementation of a variation on Gillespie''s SSA, extended to deal with diffusion of molecules over the elements of a 3D tetrahedral mesh. While it was mainly developed for simulating detailed models of neuronal signaling pathways in dendrites and around synapses, it is a general tool and can be used for studying any biochemical pathway in which spatial gradients and morphology are thought to play a role. We have implemented STEPS as a set of Python modules, which means STEPS users can use Python scripts to control all aspects of setting up the model, generating a mesh, controlling the simulation and generating and analyzing output. The core computational routines are still implemented as C/C++ extension modules for maximal speed of execution. reaction-diffusion, stochastic, signaling, molecular, python, software, simulator, reaction kinetics, 3d diffusion, signaling pathway, scripting, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Okinawa Institute of Science and Technology
has parent organization: University of Antwerp; Antwerp; Belgium
GOA ;
UA Belgium ;
Human Frontier Science Program ;
Okinawa Institute of Science and Technology
biotools:steps, nlx_143852 https://bio.tools/steps http://steps.sourceforge.net/STEPS/Home.html SCR_008742 SciCrunch Registry STochastic Engine For Pathway Simulation 2026-10-10 12:38:02 342
Eukaryote Genes
 
Resource Report
Resource Website
10+ mentions
Eukaryote Genes (RRID:SCR_008617) data or information resource, database Provides summary of gene and genomic information from eukaryotic organism databases. This includes gene symbol and full name, chromosome, genetic and molecular map information, Gene Ontology (Function/Location/Process) and gene homology, product information, links to extended gene information. eukaryote, eukaryotic gene ontology, eukaryotic genome, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Indiana University; Indiana; USA
Indiana University Center for Genomics and Bioinformatics ;
NSF DBI 0090782;
NSF DBI 9982851
Free, Freely available nif-0000-31969, biotools:eugenes, SCR_013197, nif-0000-02818 https://bio.tools/eugenes SCR_008617 SciCrunch Registry euGenes 2026-10-10 12:38:21 17
RUM
 
Resource Report
Resource Website
1+ mentions
RUM (RRID:SCR_008818) RUM software resource An alignment, junction calling, and feature quantification pipeline specifically designed for Illumina RNA-Seq data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
OMICS_01249, biotools:rum https://bio.tools/rum, https://github.com/itmat/rum/wiki SCR_008818 SciCrunch Registry Rna seq Unified Mapper 2026-10-10 12:38:07 7
QuasiRecomb
 
Resource Report
Resource Website
10+ mentions
QuasiRecomb (RRID:SCR_008812) QuasiRecomb software resource A jumping hidden Markov model that describes the generation of the viral quasispecies and a method to infer its parameters by analysing next generation sequencing data. haplotype, next-generation sequencing, virus, parameter, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:23383997 OMICS_00229, biotools:quasirecomb https://bio.tools/quasirecomb SCR_008812 SciCrunch Registry QuasiRecomb - Probabilistic inference of viral Quasispecies 2026-10-10 12:38:11 33
XPN
 
Resource Report
Resource Website
1+ mentions
XPN (RRID:SCR_008845) XPN software resource Merging Two Gene Expression Studies via Cross Platform Normalization. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
OMICS_00863, biotools:xpn https://bio.tools/xpn SCR_008845 SciCrunch Registry 2026-10-10 12:38:07 2
MuSiC
 
Resource Report
Resource Website
100+ mentions
MuSiC (RRID:SCR_008792) MuSiC software resource A set of tools aimed at determining the significance of somatic mutations discovered within a given cohort of cancer samples, incorporating the cohort''s alignment data, variant lists and any relevant clinical data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Washington University in St. Louis; Missouri; USA
PMID:22759861 THIS RESOURCE IS NO LONGER IN SERVICE biotools:MuSiC2, OMICS_00152 https://bio.tools/MuSiC2, https://github.com/ding-lab/MuSiC2/blob/master/README.md SCR_008792 SciCrunch Registry Mutational Significance In Cancer 2026-10-10 12:38:11 485
GMAP
 
Resource Report
Resource Website
500+ mentions
GMAP (RRID:SCR_008992) GMAP alignment software, data processing software, image analysis software, software application, software resource, source code THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. A software program for mapping and aligning cDNA sequences to a genome. The program maps and aligns a single sequence with minimal startup time and memory requirements, and provides fast batch processing of large sequence sets. The program generates accurate gene structures, even in the presence of substantial polymorphisms and sequence errors, without using probabilistic splice site models. Methodology underlying the program includes a minimal sampling strategy for genomic mapping, oligomer chaining for approximate alignment, sandwich DP for splice site detection, and microexon identification with statistical significance testing. mrna, est sequence, expressed sequence tag, sequence, cdna sequence, genome, cdna, bio.tools is used by: deFuse
is listed by: Debian
is listed by: bio.tools
has parent organization: Genentech
PMID:15728110 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_15072, biotools:gmap, nlx_152505 https://bio.tools/gmap, https://sources.debian.org/src/gmap/ SCR_008992 SciCrunch Registry 2026-10-10 12:38:08 599

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