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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
BXH/XCEDE Tools
 
Resource Report
Resource Website
1+ mentions
BXH/XCEDE Tools (RRID:SCR_009439) BXH/XCEDE Tools data processing software, image analysis software, software application, software resource A collection of data processing and image analysis tools for data in BXH or XCEDE format. This includes data format encapsulation/conversion, event-related analysis, QA tools, and more. These tools form the basis of the fBIRN QA procedures and are also distributed as part of the fBIRN Data Upload Scripts. analyze, c, c++, console (text based), dicom, format conversion, linux, macos, mgh/mgz, microsoft, minc, magnetic resonance, nifti, perl, posix/unix-like, quantification, sh/bash, statistical operation, unix shell, windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Function BIRN
BIRN License nlx_155583 SCR_009439 2026-09-12 01:00:59 4
metaMA
 
Resource Report
Resource Website
metaMA (RRID:SCR_000408) software resource, software toolkit Software R package for meta-analysis for microarrays. It combines either p-values or modified effect sizes from different studies to find differentially expressed genes. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
is listed by: CRAN
is related to: SMAGEXP
Scottish Government Rural and Environment Research and Analysis Directorate PMID:19628502 Free, Available for download, Freely available OMICS_03524 SCR_000408 Meta-analysis for MicroArrays, Meta analysis for MicroArrays 2026-09-12 01:02:23 0
ShapeWorks
 
Resource Report
Resource Website
1+ mentions
ShapeWorks (RRID:SCR_000424) ShapeWorks software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE.Documented on September 2, 2022. Software that is an open-source distribution of a new method for constructing compact statistical point-based models of ensembles of similar shapes that does not rely on any specific surface parameterization. The method requires very little preprocessing or parameter tuning, and is applicable to a wide range of shape analysis problems, including nonmanifold surfaces and objects of arbitrary topology. The proposed correspondence point optimization uses an entropy-based minimization that balances the simplicity of the model (compactness) with the accuracy of the surface representations. The ShapeWorks software includes tools for preprocessing data, computing point-based shape models, and visualizing the results. c++, console (text based), linux, macos, microsoft, magnetic resonance, posix/unix-like, rendering, shape analysis, surface rendering, visualization, win32 (ms windows), windows, workflow is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Utah; Utah; USA
NCRR 5P41RR012553-15;
NIGMS 8 P41 GM103545-15
THIS RESOURCE IS NO LONGER IN SERVICE nlx_155961 http://www.nitrc.org/projects/shapeworks SCR_000424 2026-09-12 01:02:23 1
VennDiagram
 
Resource Report
Resource Website
1000+ mentions
VennDiagram (RRID:SCR_002414) software resource, software toolkit Software providing a set of functions to generate high-resolution Venn and Euler plots. Includes handling for several special cases, including two-case scaling, and extensive customization of plot shape and structure. Venn and Euler plots, mac os x, unix/linux, windows, r is listed by: OMICtools
is listed by: Debian
is related to: jVenn
has parent organization: CRAN
PMID:21269502 Free, Available for download, Freely available OMICS_05570 https://sources.debian.org/src/r-cran-venndiagram/ SCR_002414 VennDiagram: Generate high-resolution Venn and Euler plots 2026-09-12 01:02:28 2138
MUMA
 
Resource Report
Resource Website
10+ mentions
MUMA (RRID:SCR_002412) MUMA software application, software resource, standalone software Software that provides guidelines for the whole process of metabolomic data interpretation, from data pre-processing, to dataset exploration and visualization, to identification of potentially interesting metabolites. Guidelines outline the following processes: preprocessing of high-throughput data (normalization and scalings); principal component analysis with help tool for choosing best-separating principal components and automatic testing for outliers; automatic univariate analysis for parametric and non-parametric data, with generation of specific reports (volcano and box plots); partial least square discriminant analysis (PLS-DA); orthogonal partial least square discriminant analysis (OPLS-DA); Statistical Total Correlation Spectroscopy (STOCSY); and Ratio Analysis Nuclear Magnetic Resonance (NMR) Spectroscopy (RANSY). standalone software, mac os x, unix/linux, windows, r, metabolomics, univariate, multivariate, data analysis is listed by: OMICtools
has parent organization: CRAN
Free, Available for download, Freely available OMICS_03370 SCR_002412 Metabolomics Univariate and Multivariate Analysis (MUMA), Metabolomic Univariate and Multivariate Analysis 2026-09-12 01:02:28 28
DicomWorks
 
Resource Report
Resource Website
1+ mentions
DicomWorks (RRID:SCR_001195) DicomWorks software application, software resource Software to help users work with DICOM files by organizing, managing and analyzing them. Key features: * a smart DICOM viewer with 4 panel display, annotations, arrows, multimodality synchronization, etc... * an export wizard to the most common picture or movie file formats * an export wizard to Microsoft PowerPoint * the most simple and compatible DICOM CD-ROM reader * the most simple and smart DICOM CD-ROM WRITER * an archiving solution with lossless compression of the data * a DICOM creation module to dicomize images from any image source (even video capture) * e-mail or FTP import end export functions (teleradiology) * 16 native localized versions dicom, windows, radiology, image analysis, anonymization, protocol, export, powerpoint, surface analysis, visualization is listed by: Biositemaps PMID:17333414
PMID:18003565
Free nif-0000-00288 http://www.dicomworks.com SCR_001195 2026-09-12 01:02:25 3
LAMP
 
Resource Report
Resource Website
1000+ mentions
LAMP (RRID:SCR_001740) LAMP software application, software resource Software for linkage and association modeling in pedigrees that uses a maximum likelihood model to extract information on genetic linkage and association from samples of unrelated individuals, sib pairs, trios and larger pedigrees (Li et al, 2005; Li et al, 2006). It provides estimates of genetic model parameters and powerful tests of association in settings where population stratification is not a concern. gene, genetic, genomic, c++, unix, linux, windows, macos, linkage, association, modeling, pedigree is listed by: Genetic Analysis Software
has parent organization: University of Michigan; Ann Arbor; USA
PMID:16642434 Free, Available for download, Freely available nlx_154103 SCR_001740 Linkage and Association Modeling in Pedigrees 2026-09-12 01:02:26 1166
nondetects
 
Resource Report
Resource Website
1+ mentions
nondetects (RRID:SCR_001702) software application, software resource, standalone software Software R package to model and impute non-detects in results of qPCR experiments.Used to directly model non-detects as missing data. mac os x, unix/linux, windows, r, assay domain, gene expression, preprocessing, technology, workflow step, qpcr, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Edelman-Gardner Foundation ;
NCI CA009363;
NCI CA138249;
NHGRI HG006853
PMID:24764462 Free, Available for download, Freely available OMICS_03938, biotools:nondetects https://bio.tools/nondetects SCR_001702 nondetects - Non-detects in qPCR data 2026-09-12 01:02:26 1
Computational Morphometry Toolkit
 
Resource Report
Resource Website
10+ mentions
Computational Morphometry Toolkit (RRID:SCR_002234) CMTK software application, software resource, software toolkit A software toolkit for computational morphometry of biomedical images, CMTK comprises a set of command line tools and a back-end general-purpose library for processing and I/O. The command line tools primarily provide the following functionality: registration (affine and nonrigid; single and multi-channel; pairwise and groupwise), image correction (MR bias field estimation; interleaved image artifact correction; EPI unwarping), processing (filters; combination of segmentations via voting and STAPLE; shape-based averaging), statistics (t-tests; general linear model). CMTK is implemented in C++ with parallel processing using POSIX Threads (SMP), OpenMP (SMP), Grand Central Dispatch (SMP), and CUDA (GPU). Supported file formats include Analyze (r/w), NIFTI (r/w), Nrrd (r/w), DICOM (read), BioRad (read). Data exchange with other toolkits, such as ITK, FSL, AFNI, SPM, etc. is thus easily accomplished. reusable library, analyze, anatomic, artifact removal, atlas application, c, c++, console (text based), cygwin, dicom, domain independent, format conversion, image display, image reconstruction, image-to-image, labeling, linear, linux, macos, microsoft, magnetic resonance, nifti-1, nrrd, posix/unix-like, principal component analysis, region of interest, registration, regression, resampling, segmentation, sh/bash, spatial transformation, statistical operation, sunos/solaris, two dimensional display, unix shell, visualization, warping, win32 (ms windows), windows, workflow is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
has parent organization: neurodebian
Free, Available for download, Freely available nlx_155536 http://www.nitrc.org/projects/cmtk, https://sources.debian.org/src/cmtk/ SCR_002234 Computational Morphometry Toolkit (CMTK) 2026-09-12 01:02:27 38
CLUSTAG
 
Resource Report
Resource Website
1+ mentions
CLUSTAG (RRID:SCR_001816) CLUSTAG software application, software resource Software application that uses hierarchical clustering and graph methods for selecting tag SNPs (single nucleotide polymorphisms). Cluster and set-cover algorithms are developed to obtain a set of tag SNPs that can represent all the known SNPs in a chromosomal region, subject to the constraint that all SNPs must have a squared correlation R2 > C with at least one tag SNP, where C is specified by the user. The program is implemented with Java, and it can run in Windows platform as well as the Unix environment. gene, genetic, genomic, java, hierarchical clustering, single nucleotide polymorphism, windows, unix is listed by: Genetic Analysis Software
has parent organization: Hong Kong Baptist University; Hong Kong; China
PMID:15585525 THIS RESOURCE IS NO LONGER IN SERVICE nlx_154273 http://hkumath.hku.hk/web/link/CLUSTAG/CLUSTAG.html SCR_001816 CLUSTAG: Hierarchical Clustering and Graph Methods for Selecting Tag SNPs 2026-09-12 01:02:26 1
Slicer3 Example Modules
 
Resource Report
Resource Website
Slicer3 Example Modules (RRID:SCR_002559) Slicer3 Example Modules software application, software development tool, software resource Example Slicer3 plugins that can be built against a Slicer3 build or a Slicer3 installation. Note: these are for 3D Slicer version 3. There is now a version 4 of 3D Slicer available. Information about extensions for version 4 can be found at the following links: http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/SlicerApplication/ExtensionsManager http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/Developers/Tutorials/BuildTestPackageDistributeExtensions analyze, c++, console (text based), computed tomography, dicom, linux, macos, microsoft, magnetic resonance, nifti, pet, spect, platform or development environment, posix/unix-like, win32 (ms windows), windows, windows nt/2000, windows vista is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: 3D Slicer
is related to: INCF Software Center
Free, Available for download, Freely available nlx_155965 SCR_002559 2026-09-12 01:02:28 0
AltAnalyze - Alternative Splicing Analysis Tool
 
Resource Report
Resource Website
50+ mentions
AltAnalyze - Alternative Splicing Analysis Tool (RRID:SCR_002951) AltAnalyze software application, software resource Software application for microarry, RNA-Seq and metabolomics analysis. For splicing sensitive platforms (RNA-Seq or Affymetrix Exon, Gene and Junction arrays), it will assess alternative exon (known and novel) expression along protein isoforms, domain composition and microRNA targeting. In addition to splicing-sensitive platforms, it provides comprehensive methods for the analysis of other data (RMA summarization, batch-effect removal, QC, statistics, annotation, clustering, network creation, lineage characterization, alternative exon visualization, gene-set enrichement and more). AltAnalyze can be run through an intuitive graphical user interface or command-line and requires no advanced knowledge of bioinformatics programs or scripting. Alternative regulated exons can be subsequently visualized in the context of proteins, domains and microRNA binding sites with the Cytoscape Plugin DomainGraph. analysis, alternative splicing, microarray, calculate, pathway, ontology, domain, microrna, targeting, splicing, microarry, rna-seq, metabolomics, mac osx, windows, ubuntu, cross platform, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Cytoscape
has parent organization: University of California at San Francisco; California; USA
PMID:20513647 Free, Available for download, Freely available nif-0000-30083, OMICS_02250, biotools:altanalyze https://bio.tools/altanalyze SCR_002951 Alternative Splicing Analysis Tool 2026-09-12 01:02:29 86
SPHARM-MAT
 
Resource Report
Resource Website
1+ mentions
SPHARM-MAT (RRID:SCR_002545) SPHARM-MAT software application, software resource, software toolkit A matlab-based 3D shape modeling and analysis toolkit, and is designed to aid statistical shape analysis for identifying morphometric changes in 3D structures of interest related to different conditions. SPHARM-MAT is implemented based on a powerful 3D Fourier surface representation method called SPHARM, which creates parametric surface models using spherical harmonics. analyze, c, matlab, microsoft, morphology, magnetic resonance, nifti, posix/unix-like, quantification, quantitative shape analysis, shape analysis, shape decomposition, spherical harmonics, surface analysis, win32 (ms windows), windows, parametric surface model, spherical harmonics, 3d, shape modeling, analysis, morphometry is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Indiana University School of Medicine; Indiana; USA
NIBIB R03EB008674-01 Free, Available for download, Freely available nlx_155952 http://www.nitrc.org/projects/spharm-mat SCR_002545 2026-09-12 01:02:28 2
Diffusion Tractography with Kalman Filter
 
Resource Report
Resource Website
Diffusion Tractography with Kalman Filter (RRID:SCR_002585) Diffusion Tractography with Kalman Filter software application, software resource Software framework which uses an unscented Kalman filter for performing tractography. At each point on the fiber the most consistent direction is found as a mixture of previous estimates and of the local model. It is very easy to expand the framework and to implement new fiber representations for it. Currently it is possible to tract fibers using two different 1-, 2-, or 3-tensor methods. Both methods use a mixture of Gaussian tensors. One limits the diffusion ellipsoids to a cylindrical shape (the second and third eigenvalue are assumed to be identical) and the other one uses a full tensor representation. The project is written in C++. It could be used both as a Slicer3 module and as a standalone commandline application. c++, diffusion mr fiber tracking, fiber tracking, microsoft, magnetic resonance, nrrd, posix/unix-like, tractography, win32 (ms windows), windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: 3D Slicer
has parent organization: Harvard Medical School; Massachusetts; USA
PMID:19694258 Free, Available for download, Freely available nlx_155990 SCR_002585 Tractography with Unscented Kalman Filter 2026-09-12 01:02:28 0
enviPick
 
Resource Report
Resource Website
1+ mentions
enviPick (RRID:SCR_003059) software resource, web site Software for sequential partitioning, clustering and peak detection of centroided LC-MS mass spectrometry data (.mzXML). Interactive result and raw data plot. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
Free, Available for download, Freely available OMICS_05010 https://rdrr.io/cran/enviPick/ SCR_003059 enviPick: Peak picking for high resolution mass spectrometry data 2026-09-12 01:02:29 2
OpenMEEG
 
Resource Report
Resource Website
100+ mentions
OpenMEEG (RRID:SCR_002510) OpenMEEG software application, software resource A C++ package for low-frequency bio-electromagnetism solving forward problems in the field of EEG and MEG with very high accuracy. algorithm, c++, eeg, meg, electrocorticography, eeg modeling, forward - inverse, macos, meg modeling, microsoft, modeling, posix/unix-like, windows, bioelectromagnetic is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is related to: Brainstorm
has parent organization: National Institute for Research in Computer Science and Control; Brittany; France
PMID:20819204
PMID:15638183
Free, Available for download, Freely available nlx_155910 http://www.nitrc.org/projects/openmeeg, https://sources.debian.org/src/libopenmeeg-dev/ SCR_002510 2026-09-12 01:02:28 112
STAPLE
 
Resource Report
Resource Website
100+ mentions
STAPLE (RRID:SCR_002590) STAPLE software application, software resource An algorithm for the Simultaneous Truth and Performance Level Estimation, which estimates a reference standard and segmentation generator performance from a set of segmentations. It has been widely applied for the validation of image segmentation algorithms, and to compare the performance of different algorithms and experts. It has also found application in the identification of a consensus segmentation, by combination of the output of a group of segmentation algorithms, and for segmentation by registration and template fusion., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. algorithm, analyze, c++, dicom, gifti, image display, linux, macos, microsoft, magnetic resonance, nifti, nrrd, posix/unix-like, quantification, rendering, segmentation, surface rendering, visualization, win32 (ms windows), windows, standard is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Harvard Medical School; Massachusetts; USA
PMID:15250643 THIS RESOURCE IS NO LONGER IN SERVICE nlx_155994 http://www.nitrc.org/projects/staple SCR_002590 Simultaneous Truth and Performance Level Estimation, STAPLE - Simultaneous Truth and Performance Level Estimation 2026-09-12 01:02:28 142
GAMMA
 
Resource Report
Resource Website
500+ mentions
GAMMA (RRID:SCR_009484) GAMMA data processing software, image analysis software, software application, software resource GAMMA suite is an open-source cross-platform data mining software package designed to analyze neuroimaging data. A neuroimaging study often focuses on biomarker detection and classification. We designed and implemented a Bayesian, multivariate, nonparametric suite of algorithms for analyzing neuroimaging data. The GAMMA suite can be used for brain morphometric analysis, lesion-deficit analysis, and functional MR data analysis. reusable library, analyze, c, c++, console (text based), computed tomography, cygwin, hp-ux, linux, macos, microsoft, modeling, magnetic resonance, nifti, pet, spect, posix/unix-like, quantification, statistical operation, volumetric analysis, win32 (ms windows), windows, neuroimaging is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) GNU General Public License nlx_155632 SCR_009484 GAMMA Suite 2026-09-12 01:00:59 692
DSI Studio
 
Resource Report
Resource Website
500+ mentions
DSI Studio (RRID:SCR_009557) DSI Studio data processing software, image analysis software, software application, software resource A software for diffusion MR images analysis. The provided functions include reconstruction (DTI, QBI, DSI, and GQI), deterministic fiber tracking, and 3D visualization. It has a window-based interface and operates on Microsoft Windows system. analyze, c++, console (text based), dicom, diffusion mr fiber tracking, diffusion spectrum, fiber tracking, image reconstruction, linux, microsoft, modeling, magnetic resonance, nifti, posix/unix-like, q-ball, quantification, super tensor, tensor metric, tractography, visualization, win32 (ms windows), windows, coregistration, analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Carnegie Mellon University; Pennsylvania; USA
BSD License nlx_155737 http://www.nitrc.org/projects/dsistudio SCR_009557 2026-09-12 01:00:59 694
zmax_edf_merge_converter
 
Resource Report
Resource Website
zmax_edf_merge_converter (RRID:SCR_022567) software application, software resource Software tool for comprehensive conversion of folder with Hypnodyne zmax EDF files into merged European Data Format. hypnodyne, Zmax, converter, EDF, merge, python, windows Free, Available for download, Freely available SCR_022567 2026-09-12 01:03:01 0

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