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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Sigma: Millicell Cell Culture Inserts Resource Report Resource Website 10+ mentions |
Sigma: Millicell Cell Culture Inserts (RRID:SCR_015799) | instrument resource | Equipment that provides physical support for cell cultures. These cell culture inserts feature attachment and suspension cells that can access media from both their apical and basolateral sides. | cell culture, culture insert, hardware, attachment, suspension cell, apical side, basolateral side, instrument, equipment | Commercially available, Available for purchase | https://drive.google.com/file/d/1iKvbwq8VXv1PtD0ItetDiDk8tUv0RwlR/view?usp=drivesdk | https://www.emdmillipore.com/US/en/product/Millicell-Cell-Culture-Inserts, MM_NF-C10504?amp%3Bbd=1&bd=1#documentation | http://www.merckmillipore.com/ES/es/product/Millicell-Cell-Culture-Inserts, MM_NF-C10504?ReferrerURL=https%3A%2F%2Fwww.google.es%2F&bd=1 | SCR_015799 | Millicell® Cell Culture Inserts | 2026-09-05 06:27:59 | 10 | |||||||
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Olympus IX-53 Resource Report Resource Website 1+ mentions |
Olympus IX-53 (RRID:SCR_015801) | IX-53 | resource | Equipment that is a microscope for routine inverted microscopic analysis. Its features include pre-centered phase contrast, relief contrast, and UIS2 DIC optics for visualization across all magnifications for both thin and thick specimens. | microscope, inverted microscope, routine inverted microscopic analysis, phase contrast, relief contrast, uis2 dic optic, hardware, instrument, equipment | is provided by: Olympus | Commercially available, Available for purchase | SCR_015801 | IX53, IX53 Inverted Microscope, Olympus IX53 Inverted Microscope | 2026-09-05 06:27:59 | 3 | ||||||||
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Thermo Fisher: StepOnePlus Real-Time PCR System Resource Report Resource Website 50+ mentions |
Thermo Fisher: StepOnePlus Real-Time PCR System (RRID:SCR_015805) | data acquisition software, data processing software, instrument resource, software application, software resource | Equipment and software system that is a real-time thermal cycler for intuitive data analysis of polymerase chain reactions. It comes with analysis software, instrument control software, and a LED-based 4-color optical recording feature. | image acquisition software, genotype, real time pcr, qPCR, thermal cycler, hardware, pcr, polymerase chain reaction, instrument, equipment | Commercially available, Available for purchase, Runs on Windows | SCR_015805 | StepOnePlus, StepOnePlus™ Real-Time PCR System | 2026-09-05 06:27:59 | 58 | ||||||||||
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CED: Power1401 Resource Report Resource Website 10+ mentions |
CED: Power1401 (RRID:SCR_016040) | instrument resource | Data acquisition interface from Cambridge Electronic Design Limited. Works with Spike2 to provide continuous acquisition tasks. Records waveform data, digital and marker information, and can generate waveform and digital outputs simultaneously for real-time, multi-tasking experiment control. | Cambridge Electronic Design Limited, equipment, hardware, instrument, USEDit |
is listed by: USEDit works with: Spike2 Software |
Restricted | https://drive.google.com/file/d/1fl3Sbk3t-vRgPgDNMBbZQuLSBIdJUPsO/view?usp=drivesdk | SCR_017282 | SCR_016040 | , POWER1401-3 Data Acquisition Interface, Power1401-3A, CED Power1401 3A | 2026-09-05 06:28:02 | 15 | |||||||
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Grass Stimulator Model S88 Resource Report Resource Website 1+ mentions |
Grass Stimulator Model S88 (RRID:SCR_016192) | resource | Hardware that is a electrical pulse generator. | hardware, instrument, equipment, electricity, pulse, stimulation, generator | Commercially available | SCR_016192 | Cyberonics VNS 103, S88 DUAL OUTPUT SQUARE PULSE, Pulse Stimulator, Grass Technologies Stimulator Pulse | 2026-09-05 06:28:05 | 4 | ||||||||||
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Localite TMS Navigator Resource Report Resource Website 1+ mentions |
Localite TMS Navigator (RRID:SCR_016126) | resource | An instrument. Navigation system for transcranial magnetic stimulation (TMS). | hardware, instrument, equipment, tms, neuroimaging, neuroscience, neurology, transcranial, magnetic, stimulation | SCR_016126 | 2026-09-05 06:28:04 | 4 | ||||||||||||
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Prucka CardioLab System Resource Report Resource Website |
Prucka CardioLab System (RRID:SCR_016180) | resource | Prucka CardioLab system delivers the EP data and visualization we need for electrophysiological study and catheter ablation. | hardware, instrument, equipment, cardiology, heart, electrophysiology, catheter, ablation | SCR_016180 | 2026-09-05 06:28:05 | 0 | ||||||||||||
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Channelrhodopsin-2 enables optical activation of neurons Resource Report Resource Website 1+ mentions |
Channelrhodopsin-2 enables optical activation of neurons (RRID:SCR_008833) | Channelrhodopsin-2 enables optical activation of neurons | material service resource, production service resource, resource, service resource | Laser tool that enables neurons to be optically silenced by pulses of yellow light, the light-activated chloride pump halorhodopsin (Halo), in a paper entitled Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. Temporally precise, noninvasive control of activity in well-defined neuronal populations is a long-sought goal of systems neuroscience. We adapted for this purpose the naturally occurring algal protein Channelrhodopsin-2, a rapidly gated light-sensitive cation channel, by using lentiviral gene delivery in combination with high-speed optical switching to photostimulate mammalian neurons. We demonstrate reliable, millisecond-timescale control of neuronal spiking, as well as control of excitatory and inhibitory synaptic transmission. This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers. The quest to determine how precise neural activity patterns mediate computation, behavior, and pathology would be greatly aided by a set of tools for reliably activating and inactivating genetically targeted neurons, in a temporally precise and rapidly reversible fashion. Having earlier adapted a light-activated cation channel, 1channelrhodopsin-2 (ChR2), for allowing neurons to be stimulated by blue light, we searched for a complementary tool that would enable optical neuronal inhibition, driven by light of a second color. Here we report that targeting the 1codon-optimized form of the light-driven chloride pump halorhodopsin from the archaebacterium Natronomas pharaonis (hereafter abbreviated Halo) to genetically-specified neurons enables them to be silenced reliably, and reversibly, by millisecond-timescale pulses of yellow light. We show that trains of yellow and blue light pulses can drive high-fidelity sequences of hyperpolarizations and depolarizations in neurons simultaneously expressing yellow light-driven Halo and blue light-driven ChR2, allowing for the first time manipulations of neural synchrony without perturbation of other parameters such as spiking rates. The Halo/ChR2 system thus constitutes a powerful toolbox for multichannel photoinhibition and photostimulation of virally or transgenically targeted neural circuits without need for exogenous chemicals, enabling systematic analysis and engineering of the brain, and quantitative bioengineering of excitable cells. | hardware, instrument, equipment | has parent organization: Massachusetts Institute of Technology; Massachusetts; USA; | Anonymous donor ; MIT Media Lab ; Helen Hay Whitney Foundation |
PMID:17375185 | nlx_144630 | http://channelrhodopsin.org | SCR_008833 | 2026-09-05 06:31:55 | 3 | ||||||
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Agilent: 4200 TapeStation System Resource Report Resource Website 50+ mentions |
Agilent: 4200 TapeStation System (RRID:SCR_018435) | instrument resource | Benchtop genetic analyzer. Electrophoresis system for DNA and RNA sample quality control. It can be used for next generation sequencing or Biobank workflow. | Benchtop Genetic Analyzer, Instrument, Equipment, Agilent, USEDit, Next Generation Sequencing, ABRF, NGS | is listed by: USEDit | https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_018435.pdf | Model_Number_4200 TapeStation, , SCR_018444, SCR_019398, SCR_019395 | https://www.agilent.com/cs/library/datasheets/public/5991-6029EN.pdf | SCR_018435 | , Agilent 4200 Tapestation Genetic Analyzer, Agilent 4200 TapeStation | 2026-09-05 06:30:55 | 63 | |||||||
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Thermo Fisher: Applied Biosystems: GeneAmp 9700 PCR Thermocycler System Resource Report Resource Website 10+ mentions |
Thermo Fisher: Applied Biosystems: GeneAmp 9700 PCR Thermocycler System (RRID:SCR_018436) | instrument resource | Automated PCR instrument for automated amplification of nucleic acids with Polymerase Chain Reaction. It has reaction volumes of up to 50 uL and sample temperature range of 4 to 99.9 C. | Matrix Assisted Laser Desorption Ionization Time of Flight Instrument, Instrument, Equipment, Applied Biosystems, USEDit, ABRF | is listed by: USEDit | https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_018436.pdf | SCR_018448, SCR_019577, Model_Number_9700 | https://assets.thermofisher.com/TFS-Assets/LSG/manuals/cms_040970.pdf | SCR_018436 | 2026-09-05 06:30:55 | 13 | ||||||||
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Chromeleon Chromatography Data System (CDS) Software Resource Report Resource Website 10+ mentions |
Chromeleon Chromatography Data System (CDS) Software (RRID:SCR_016874) | CDS | software resource, software toolkit | Software system to support chromatography operations, to ensure data quality and manage all the analytical processes from instrument control, to raw data storage and processing, through to generating the final results. | Thermofisher, system, chromatography, operation, data, quality, manage, analytical, process, instrument, control | Commercially available | SCR_016874 | Chromeleon Chromatography Data System, Chromeleon Chromatography Data System (CDS), Dionex Chromeleon7 | 2026-09-05 06:33:02 | 11 | |||||||||
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American Optical: 860 Sliding Microtome Resource Report Resource Website 1+ mentions |
American Optical: 860 Sliding Microtome (RRID:SCR_018434) | instrument resource | THIS REOURCE IS NO LONGER IN SERVICE. Documented on September 29,2023. Sliding microtome used for cutting hard objects such as bone, wood, frozen celloidin, and paraffin preparations. Cutting thickness is adjustable from 1 to 40 microns. | Sliding Microtome, Instrument, Equipment, American Optical, USEDit, ABRF | is listed by: USEDit | THIS REOURCE IS NO LONGER IN SERVICE | https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_018434.pdf | SCR_018451, SCR_019570 | https://rankinbiomed.com/wp-content/uploads/AO-860-Sliding-Microtome-Manual.pdf | SCR_018434 | 2026-09-05 06:33:04 | 1 | |||||||
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Atago: PAL-10S Pocket Refractometer Resource Report Resource Website |
Atago: PAL-10S Pocket Refractometer (RRID:SCR_018439) | instrument resource | Digital hand held pocket refractometer that measures urine specific gravity. It has measurement temperature of 10 to 35 C and sample volume of 0.3ml. | Pocket Refractometer, Instrument, Equipment, Atago, USEDit, ABRF | is listed by: USEDit | Commercially available | https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_018439.pdf | SCR_018449, SCR_019583, Model_Number_PAL_10S | https://www.novatech-usa.com/pdf/Atago%20PAL-10S%20Refractometer%20Datasheet.pdf | SCR_018439 | 2026-09-05 06:33:04 | 0 | |||||||
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Sutter: P-2000 Laser Micropipette Puller Resource Report Resource Website 1+ mentions |
Sutter: P-2000 Laser Micropipette Puller (RRID:SCR_018640) | instrument resource | Microprocessor controlled, CO2 laser based micropipette puller.Default configuration allows fabrication of micropipettes for intracellular recording, patch clamping, microinjection and microperfusion.Can store up to 100 separate programs, each consisting of up to 8 command lines. The five parameters set in each command line allow exquisite control of the micropipette taper geometry. Allows the use of wide range of glass diameters from 0.125 to 1.2 mm. | Laser Micropipette Puller, Instrument, Equipment, USEDit, ABRF | is listed by: USEDit | Commercially available | SCR_020537, SCR_020213, Model_Number_P2000 | https://www.sutter.com/manuals/P-2000_OpMan.pdf | SCR_018640 | 2026-09-05 06:33:05 | 3 | ||||||||
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HORNET CENTER FOR AUTONOMIC NERVE RECORDING AND STIMULATION SYSTEMS Resource Report Resource Website |
HORNET CENTER FOR AUTONOMIC NERVE RECORDING AND STIMULATION SYSTEMS (RRID:SCR_023681) | CARSS | software repository, software resource | Parylene MEA Fabrication is related to SPARC. Repository for standard fabrication procedure for Parylene C microelectrode arrays and similar devices. | Instrument, equipment, device, Parylene MEA Fabrication, microelectrode arrays, Parylene C microelectrode arrays |
is related to: SPARC Portal is related to: SPARC Request |
Free, Freely available | SCR_023681 | 2026-09-05 06:33:15 | 0 | |||||||||
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NanoString: nCounter Analysis System Resource Report Resource Website 10+ mentions |
NanoString: nCounter Analysis System (RRID:SCR_021712) | nCounter | instrument resource | System includes hardware and software. Options include nCounter SPRINT,nCounter MAX or nCounter FLEX. Platform used for multiplex analysis of up to 800 RNA, DNA, or protein targets. System can be combined with GeoMx Digital Spatial Profiler (DSP) to enable high-plex, spatially-resolved RNA, and protein quantification. | Multiplex analysis, RNA analysis, DNA analysis, Protein analysis, NanoString Differential Expression, NanoString, analysis system, instrument, equipment, USEDit, ABRF | is listed by: USEDit | Commercially available | SCR_021712 | nCounter Analysis System, Bruker nCounter Analysis System | 2026-09-05 06:29:44 | 36 | ||||||||
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CellScale: MicroTester G2 system Resource Report Resource Website 1+ mentions |
CellScale: MicroTester G2 system (RRID:SCR_022034) | instrument resource | System includes MicroTester G2 device and software. MicroTester G2 is mechanical test device that can be used to test properties of variety of tissues and materials. Main components of device are load application microbeam, actuators, imaging system, and fluid bath/test chamber. MicroTester G2 software is divided into two modules: data collection module and review and analysis module. | instrument, equipment, USEDit, CellScale, mechanical test device, test properties, tissues, materials | is listed by: USEDit | Restricted | https://www.cellscale.com/downloads2/MicroTester%20User%20ManualG2.pdf | SCR_022034 | SquisherJoy | 2026-09-05 06:29:49 | 3 | ||||||||
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CoolLED: pE-300ultra Resource Report Resource Website 1+ mentions |
CoolLED: pE-300ultra (RRID:SCR_021972) | instrument resource | Highly controllable fluorescence microscopy Illumination System which offers broad spectrum LED illumination for imaging most common fluorophores. System offers precise control over wavelength irradiance and shuttering. Used for LED microscope lighting. | CoolLED, LED microscope lighting, LED illumination, imaging, fluorophores, control over wavelength irradiance and shuttering, instrument, equipment, USEDit | is listed by: USEDit | Restricted | , Model_Number_pE-300ultra | SCR_021972 | 2026-09-05 06:29:48 | 3 | |||||||||
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Alveole: PRIMO photopatterning module Resource Report Resource Website 1+ mentions |
Alveole: PRIMO photopatterning module (RRID:SCR_021941) | PRIMO | instrument resource | Photopatterning device for performing micropatterning, microfabrication and hydrogel polymerization.Part of PRIMO system. | Alvéole, photopatterning module, micropatterning, microfabrication, hydrogel polymerization, instrument, equipment | is related to: Alveole Leonardo | Restricted | https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_021941.pdf | SCR_021941 | Alvéole PRIMO, Alveole PRIMO | 2026-09-05 06:29:48 | 1 | |||||||
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Zeitz: DMZ Universal Electrode Puller Resource Report Resource Website 1+ mentions |
Zeitz: DMZ Universal Electrode Puller (RRID:SCR_022056) | instrument resource | Horizontal pipette puller to pull and polish microelectrodes from borosilicate capillaries. | Zeitz-Instrumente Vertriebs GmbH, electrode puller, horizontal pipette puller, pull and polish microelectrodes, borosilicate capillaries, instrument, equipment, USEDit | is listed by: USEDit | Restricted | https://www.zeitz-puller.com/support/manual/ | SCR_022056 | DMZ Zeitz Puller | 2026-09-05 06:29:49 | 4 |
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