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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
iMir
 
Resource Report
Resource Website
10+ mentions
iMir (RRID:SCR_009496) iMir software resource A modular pipeline for comprehensive analysis of smallRNA-Seq data, comprising specific tools for adapter trimming, quality filtering, DE analysis, target prediction by integrating multiple open source modules and resources in an automated workflow. unix/linux, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24330401 Apache License OMICS_00358, biotools:imir https://bio.tools/imir SCR_009496 2026-08-29 11:23:19 11
SpliceMap
 
Resource Report
Resource Website
10+ mentions
SpliceMap (RRID:SCR_009650) SpliceMap software resource A de novo splice junction discovery and alignment tool. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Stanford University; Stanford; California
PMID:25577377
PMID:20371516
OMICS_01252, biotools:splicemap https://bio.tools/splicemap SCR_009650 2026-08-29 11:23:22 21
IsoEM
 
Resource Report
Resource Website
10+ mentions
IsoEM (RRID:SCR_009993) IsoEM software resource Software package that can be used to infer isoform and gene expression levels from high-throughput transcriptome sequencing (RNA-Seq) data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Connecticut; Connecticut; USA
biotools:isoem, OMICS_01278 https://bio.tools/isoem SCR_009993 2026-08-29 11:23:38 10
BitSeq
 
Resource Report
Resource Website
10+ mentions
BitSeq (RRID:SCR_009904) BitSeq software resource A software application for inferring expression levels of individual transcripts from sequencing (RNA-Seq) data and estimating differential expression (DE) between conditions. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1093/bioinformatics/btv483
DOI:10.1093/bioinformatics/bts260
, OMICS_01269, biotools:bitseq https://bio.tools/bitseq, https://sources.debian.org/src/bitseq/, SCR_009904 2026-08-29 11:23:23 20
BEAST
 
Resource Report
Resource Website
5000+ mentions
BEAST (RRID:SCR_010228) data analysis software, data processing software, sequence analysis software, software application, software repository, software resource A cross-platform software program for Bayesian MCMC analysis of molecular sequences. It is entirely orientated towards rooted, time-measured phylogenies inferred using strict or relaxed molecular clock models. It can be used as a method of reconstructing phylogenies but is also a framework for testing evolutionary hypotheses without conditioning on a single tree topology. BEAST uses MCMC to average over tree space, so that each tree is weighted proportional to its posterior probability. We include a simple to use user-interface program for setting up standard analyses and a suit of programs for analysing the results. bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: TempEst
is related to: BEAST2
is related to: PhyDyn
has parent organization: University of Edinburgh; Scotland; United Kingdom
DOI:10.1186/1471-2148-7-214 nlx_156859, OMICS_04233, biotools:beast, SCR_015988 http://www.nitrc.org/projects/beast-library, https://bio.tools/beast, https://sources.debian.org/src/beast-mcmc/ http://beast.bio.ed.ac.uk/Main_Page SCR_010228 BEaST Segmentation Library, Beast Software 2026-08-29 11:23:39 6777
WEBLOGO
 
Resource Report
Resource Website
1000+ mentions
WEBLOGO (RRID:SCR_010236) data access protocol, service resource, software resource, web service Web application to generate sequence logos, graphical representations of patterns within multiple sequence alignment. Designed to make generation of sequence logos easy. Sequence logo generator. Generate sequence logo, pattern graphical representation, multiple sequence alignment, sequence logo generator, amino acid sequence alignment, nucleic acid sequence alignment, sequence alignment representation, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of California at Berkeley; Berkeley; USA
NHGRI K22 HG00056;
NIGMS P50 GM62412;
Searle Scholars program
PMID:15173120 Free, Available for download, Freely available nlx_156853, biotools:weblogo_3 http://weblogo.threeplusone.com/, https://bio.tools/weblogo_3 SCR_010236 WebLogo Version 2.8.2, WebLogo3, WebLogo 2026-08-29 11:23:39 3980
GenoTan
 
Resource Report
Resource Website
1+ mentions
GenoTan (RRID:SCR_007935) GenoTan software resource A free software tool to identify length variation of microsatellites from short sequence reads. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24135263 GNU General Public License, v3 biotools:genotan https://bio.tools/genotan SCR_007935 GenoTan - Genotyping of microsatellite loci 2026-08-29 11:23:20 1
VISTA Enhancer Browser
 
Resource Report
Resource Website
100+ mentions
VISTA Enhancer Browser (RRID:SCR_007973) VISTA Enhancer Browser data or information resource, data repository, database, service resource, storage service resource Resource for experimentally validated human and mouse noncoding fragments with gene enhancer activity as assessed in transgenic mice. Most of these noncoding elements were selected for testing based on their extreme conservation in other vertebrates or epigenomic evidence (ChIP-Seq) of putative enhancer marks. Central public database of experimentally validated human and mouse noncoding fragments with gene enhancer activity as assessed in transgenic mice. Users can retrieve elements near single genes of interest, search for enhancers that target reporter gene expression to particular tissue, or download entire collections of enhancers with defined tissue specificity or conservation depth. human, noncoding fragment, mutant mouse strain, molecular neuroanatomy resource, image, telencephalon, development, genome, enhancer, dna fragment, embryo, embryonic mouse, brain, neural tube, eye, ear, heart, tail, limb, nose, cranial nerve, trigeminal, dorsal root ganglia, face, branchial arch, gene expression, annotation, vector, transgenic embryo, lacz reporter vector, lacz, biomaterial supply resource, in vivo, image collection, transcriptional enhancer, chip-seq, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: NIF Data Federation
is related to: One Mind Biospecimen Bank Listing
is related to: OMICtools
has parent organization: Lawrence Berkeley National Laboratory
American Heart Association ;
DOE contract DE-AC02-05CH11231;
DOE DE020060;
NHGRI HG003988;
NHLBI HL066681;
NIDCR ;
NINDS NS062859
PMID:17130149 Free, Freely available nif-0000-03637, OMICS_01568, biotools:vista_enhancer_browser https://bio.tools/vista_enhancer_browser SCR_007973 2026-08-29 11:22:56 249
T1DBase
 
Resource Report
Resource Website
100+ mentions
T1DBase (RRID:SCR_007959) data or information resource, data repository, database, resource, service resource, storage service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 26,2019. In October 2016, T1DBase has merged with its sister site ImmunoBase (https://immunobase.org). Documented on March 2020, ImmunoBase ownership has been transferred to Open Targets (https://www.opentargets.org). Results for all studies can be explored using Open Targets Genetics (https://genetics.opentargets.org). Database focused on genetics and genomics of type 1 diabetes susceptibility providing a curated and integrated set of datasets and tools, across multiple species, to support and promote research in this area. The current data scope includes annotated genomic sequences for suspected T1D susceptibility regions; genetic data; microarray data; and global datasets, generally from the literature, that are useful for genetics and systems biology studies. The site also includes software tools for analyzing the data. genetics, beta cell, gene, variant, region, genomics, gene expression, genome-wide association study, data analysis service, bio.tools is used by: NIF Data Federation
is used by: NIDDK Information Network (dkNET)
is listed by: NIDDK Information Network (dkNET)
is listed by: Debian
is listed by: bio.tools
is related to: dkCOIN
has parent organization: University of Cambridge; Cambridge; United Kingdom
Type 1 diabetes. Diabetes Wellcome Trust ;
NIDDK ;
Juvenile Diabetes Research Foundation
PMID:20937630 THIS RESOURCE IS NO LONGER IN SERVICE. nif-0000-03531, biotools:t1dbase https://bio.tools/t1dbase SCR_007959 T1DBase - Type 1 Diabetes Database 2026-08-29 11:23:04 147
HilbertVis
 
Resource Report
Resource Website
1+ mentions
HilbertVis (RRID:SCR_007862) HilbertVis software resource Software tool that allows to display very long data vectors in a space-efficient manner, allowing the user to visually judge the large scale structure and distribution of features simultaneously with the rough shape and intensity of individual features. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: European Bioinformatics Institute
DOI:10.1093/bioinformatics/btp152 OMICS_00627, biotools:hilbertvis https://bio.tools/hilbertvis, https://sources.debian.org/src/r-bioc-hilbertvis/ SCR_007862 2026-08-29 11:23:03 4
BRIG
 
Resource Report
Resource Website
500+ mentions
BRIG (RRID:SCR_007802) BRIG software resource A cross-platform (Windows/Mac/Unix) application that can display circular comparisons between a large number of genomes, with a focus on handling genome assembly data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
DOI:10.1186/1471-2164-12-402 OMICS_00929, biotools:brig https://bio.tools/brig, https://sources.debian.org/src/brig/ SCR_007802 BLAST Ring Image Generator 2026-08-29 11:23:18 561
dbEST
 
Resource Report
Resource Website
100+ mentions
dbEST (RRID:SCR_008132) data or information resource, data repository, database, service resource, storage service resource Database as a division of GenBank that contains sequence data and other information on single-pass cDNA sequences, or Expressed Sequence Tags, from a number of organisms. data, sequence, single, pass, cDNA, express, tag, bio.tools, gold standard is listed by: Debian
is listed by: bio.tools
has parent organization: NCBI
PMID:8401577 biotools:dbest, nif-0000-20937, r3d100010648 http://www.ncbi.nlm.nih.gov/dbEST/, https://bio.tools/dbest, https://doi.org/10.17616/R3FG8P SCR_008132 database Expressed Sequence Tag (EST), database Expressed Sequence Tag 2026-08-29 11:23:26 186
lobSTR
 
Resource Report
Resource Website
10+ mentions
lobSTR (RRID:SCR_008030) lobSTR software resource A software tool for profiling Short Tandem Repeats (STRs) from high throughput sequencing data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
PMID:22522390 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00109, biotools:lobstr https://bio.tools/lobstr SCR_008030 lobSTR - Profiling STRs in personal genomes 2026-08-29 11:22:58 47
ActiveDriver
 
Resource Report
Resource Website
10+ mentions
ActiveDriver (RRID:SCR_008104) ActiveDriver data analysis software, data processing software, sequence analysis software, software application, software resource A statistical method for interpreting variations in protein sequence (e.g. coding SNPs in the population, SNVs in cancer genomes) in the context of protein post-translational signaling modifications. Protein sequence variation, variation interpretation, protein sequence, protein post-translational signaling modifications, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:ActiveDriver, OMICS_00140 http://reimandlab.org/software/activedriver/, https://cran.r-project.org/web/packages/ActiveDriver/ActiveDriver.pdf, https://bio.tools/ActiveDriver SCR_008104 2026-08-29 11:22:59 27
QIIME
 
Resource Report
Resource Website
10000+ mentions
QIIME (RRID:SCR_008249) data analysis software, data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 23,2023.Software package for comparison and analysis of microbial communities, primarily based on high-throughput amplicon sequencing data, but also supporting analysis of other types of data. QIMME analyzes and transforms raw sequencing data generated on Illumina or other platforms to publication quality graphics and statistics. microbiome, microbial community, sequence data, data analysis software, bio.tools is used by: SortMeRNA
is used by: Nephele
is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of Colorado Boulder; Colorado; USA
DOI:10.1038/nmeth.f.303 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01118, SCR_011948, OMICS_01521, biotools:qiime https://bio.tools/qiime SCR_008249 Quantitative Insights Into Microbial Ecology 2026-08-29 11:23:10 11177
IsaCGH
 
Resource Report
Resource Website
IsaCGH (RRID:SCR_008375) IsaCGH software resource Software to analyze CNV that will now normalize arrays CGH and it will visually integrate different genome annotations. microarray, array cgh, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
OMICS_00727, biotools:isacgh https://bio.tools/isacgh SCR_008375 2026-08-29 11:23:29 0
G protein receptor interaction feature finding instrument
 
Resource Report
Resource Website
10+ mentions
G protein receptor interaction feature finding instrument (RRID:SCR_008343) analysis service resource, production service resource, resource, service resource Griffin (G-protein-receptor interacting feature finding instrument) is a high-throughput system to predict GPCR - G-protein coupling selectively with the input of GPCR sequence and ligand molecular weight. This system consists of two parts: 1) HMM section using family specific multiple alignment of GPCRs, 2) SVM section using physico-chemical feature vectors in GPCR sequence. G-protein coupled receptors (GPCR), which is composed of seven transmembrane helices, play a role as interface of signal transduction. The external stimulation for GPCR, induce the coupling with G-protein (Gi/o, Gq/11, Gs, G12/13) followed by different kinds of signal transduction to inner cell. About half of distributed drugs are intending to control this GPCR - G-protein binding system, and therefore this system is important research target for the development of effective drug. For this purpose, it is necessary to monitor, effectively and comprehensively, of the activation of G-protein by identifying ligand combined with GPCR. Since, at present, it is difficult to construct such biochemical experiment system, if the answers for experimental results can be prepared beforehand by using bioinformatics techniques, large progress is brought to G-protein related drug design. Previous works for predicting GPCR-G protein coupling selectivity are using sequence pattern search, statistical models, and HMM representations showed high sensitivity of predictions. However, there are still no works that can predict with both high sensitivity and specificity. In this work we extracted comprehensively the physico-chemical parameters of each part of ligand, GPCR and G-protein, and choose the parameters which have strong correlation with the coupling selectivity of G-protein. These parameters were put as a feature vector, used for GPCR classification based on SVM. drug, alignment, biochemical, bioinformatic, coupling, gpcr, g-protein, helix, instrument, interface, ligand, molecular, pattern, physico-chemical, receptor interacting, sequence, signal transduction, stimulation, svm, system, technique, transmembrane, weight, instrument, equipment, hardware, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Computational Biology Research Center Core Facility
National Institute of Advanced Industrial Science and Technology nif-0000-25210, biotools:griffin https://bio.tools/griffin SCR_008343 Griffin 2026-08-29 11:23:13 21
COPASI
 
Resource Report
Resource Website
100+ mentions
COPASI (RRID:SCR_014260) COPASI data analysis software, data processing software, simulation software, software application, software resource, standalone software Software application for simulation and analysis of biochemical network models and their dynamics. COPASI supports models in the SBML standard and can simulate their behavior using ODEs or Gillespies stochastic simulation algorithm. Arbitrary discrete events can be included in such simulations. Models in COPASI are based on reactions that convert a set of species into another set of species. Simulation can be performed either with stochastic kinetics or with differential equations. COPASI also includes various methods of analysis and data visualization. standalone software, simulation software, data analysis, biochemical system simulator, biochemical network model, biochemical network dynamics, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1093/bioinformatics/btl485 Free, Available for download, Acknowledgement requested biotools:copasi https://bio.tools/copasi SCR_014260 COPASI: Biochemical System Simulator 2026-08-29 11:24:44 445
CYANA
 
Resource Report
Resource Website
100+ mentions
CYANA (RRID:SCR_014229) data analysis software, data processing software, software application, software resource Software for automated structure calculation of biological macromolecules on basis of conformational constraints from nuclear magnetic resonance. Program for automated NMR protein structure calculation. CYANA requires a sufficient list of assigned chemical shifts and lists of cross-peak positions and columns from 2D, 3D, or4D NOESY spectra in order to calculate the assignment of the NOESY cross-peaks and the 3D structure of the protein in solution. protein structure, nmr, noesy, 3d structure, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Goethe University Frankfurt am Main; Hessen; Germany
has parent organization: RIKEN
PMID:15318003
PMID:25801209
Available to the academic community, Available to commercial user, Pay for license SCR_021949, biotools:cyana http://www.las.jp/english/products/cyana.html, https://bio.tools/cyana, https://dbpedia.org/page/CYANA_(software) SCR_014229 2026-08-29 11:24:51 428
Coot
 
Resource Report
Resource Website
10000+ mentions
Coot (RRID:SCR_014222) COOT data or information resource, model, simulation software, software application, software resource, software toolkit Software for macromolecular model building, model completion and validation, and protein modelling using X-ray data. Coot displays maps and models and allows model manipulations such as idealization, rigid-body fitting, ligand search, Ramachandran plots, non-crystallographic symmetry and more. Source code is available. software toolkit, simulation software, model manipulation, protein modeling, bio.tools is used by: PDB-REDO
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: MolProbity
has parent organization: MRC Laboratory of Molecular Biology
PMID:15572765 Available for download, Acknowledgement requested biotools:coot http://strucbio.biologie.uni-konstanz.de/ccp4wiki/index.php/Coot, https://bio.tools/coot SCR_014222 Crystallographic Object-Oriented Toolkit 2026-08-29 11:24:43 15682

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