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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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Machine Learning Made Easy Resource Report Resource Website 1+ mentions |
Machine Learning Made Easy (RRID:SCR_024439) | MLme | software resource, software toolkit | Software toolkit for Machine Learning Driven Data Analysis. Simplifies machine learning for data exploration, visualization and analysis. | Machine Learning Driven Data Analysis, | Federal Ministry of Education and Research of Germany ; NIDDK R01 DK127673; Swiss National Science Foundation ; Wings for Life Spinal Cord Research Foundation |
PMID:37461685 | Free, Available for download, Freely available | SCR_024439 | 2026-08-29 11:29:12 | 1 | ||||||||
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Diabetic Complications Consortium Resource Report Resource Website 100+ mentions |
Diabetic Complications Consortium (RRID:SCR_001415) | DiaComp | biomaterial supply resource, material resource, tissue bank | Consortium serving the diabetic complications community that sponsors annual meetings in complications-relevant scientific areas, solicits and funds pilot projects in high impact areas of complications research, and provides resources and data including animal models, protocols and methods, validation criteria, reagents and resources, histology, publications and bioinformatics for researchers conducting diabetic complications research. | diabetes, antibody, animal model, assay, experiment, histology, protocol, strain, phenotype, metabolic, cardiovascular, image, data set, community building portal, consortium, FASEB list |
is used by: NIF Data Federation is used by: NIDDK Information Network (dkNET) is listed by: NIDDK Information Network (dkNET) is listed by: One Mind Biospecimen Bank Listing is related to: dkCOIN has parent organization: Augusta University; Georgia; USA |
Diabetes, Diabetic complication, Nephropathy, Neuropathy, Retinopathy, Wound healing, Cardiomyopathy, Uropathy | NIDDK ; JDRF |
Free, Freely Available | nlx_152636 | http://www.amdcc.org/ | SCR_001415 | Animal Models of Diabetic Complications Consortium, AMDCC | 2026-08-29 11:29:12 | 237 | ||||
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UniProt Resource Report Resource Website 10000+ mentions |
UniProt (RRID:SCR_002380) | UniProt | data or information resource, database | Collection of data of protein sequence and functional information. Resource for protein sequence and annotation data. Consortium for preservation of the UniProt databases: UniProt Knowledgebase (UniProtKB), UniProt Reference Clusters (UniRef), and UniProt Archive (UniParc), UniProt Proteomes. Collaboration between European Bioinformatics Institute (EMBL-EBI), SIB Swiss Institute of Bioinformatics and Protein Information Resource. Swiss-Prot is a curated subset of UniProtKB. | collection, protein, sequence, annotation, data, functional, information |
is used by: LIPID MAPS Proteome Database is used by: ChannelPedia is used by: Open PHACTS is used by: DisGeNET is used by: Smart Dictionary Lookup is used by: MitoMiner is used by: Cytokine Registry is used by: MobiDB is used by: Pathway Analysis Tool for Integration and Knowledge Acquisition is used by: Phospho.ELM is used by: GEROprotectors is used by: SwissLipids is recommended by: NIDDK Information Network (dkNET) is recommended by: National Library of Medicine is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is listed by: re3data.org is listed by: LabWorm is related to: Clustal W2 is related to: UniProt DAS is related to: UniParc at the EBI is related to: ProDom is related to: LegumeIP is related to: Pathway Commons is related to: NIH Data Sharing Repositories is related to: FlyMine is related to: IMEx - The International Molecular Exchange Consortium is related to: 3D-Interologs is related to: Biomine is related to: EBIMed is related to: STOP is related to: Coremine Medical is related to: BioExtract is related to: STRAP is related to: GOTaxExplorer is related to: GoAnnotator is related to: IT-GOM: Integrated Tool for IC-based GO Semantic Similarity Measures is related to: Whatizit is related to: MOPED - Model Organism Protein Expression Database is related to: Polbase is related to: PredictSNP is related to: PSICQUIC Registry is related to: IntAct is related to: p300db is related to: UniProt Proteomes is related to: SARS-CoV-2 mutation effects and 3D structure prediction from sequence covariation has parent organization: European Bioinformatics Institute has parent organization: SIB Swiss Institute of Bioinformatics has parent organization: Protein Information Resource is parent organization of: UniProtKB is parent organization of: NEWT is parent organization of: UniParc is parent organization of: UniProt Chordata protein annotation program is parent organization of: UniRef works with: Genotate works with: CellPhoneDB works with: MOLEonline works with: MiMeDB |
ARUK ; British Heart Foundation ; EMBL ; NCI ; NCRR P20 RR016472; NEI ; NHGRI P41 HG02273; NHGRI U24 HG007722; NHGRI U41 HG006104; NHLBI ; NIAID ; NIA ; NIDDK ; NIGMS 5R01GM080646; NIGMS R01 GM080646; NIMH ; NLM G08 LM010720; NSF DBI-0850319; PDUK |
PMID:19843607 PMID:18836194 PMID:18045787 PMID:17142230 PMID:16381842 PMID:15608167 PMID:14681372 |
nif-0000-00377, SCR_018750, r3d100010357 | http://www.ebi.uniprot.org, http://www.uniprot.org/uniprot/, http://www.pir.uniprot.org, ftp://ftp.uniprot.org, https://doi.org/10.17616/R3BW2M | SCR_002380 | , The Universal Protein Resource, Universal Protein Resource, UNIPROT Universal Protein Resource | 2026-08-29 11:29:17 | 19823 | |||||
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Integrated Islet Distribution Program (IIDP) Resource Report Resource Website 100+ mentions Rating or validation data |
Integrated Islet Distribution Program (IIDP) (RRID:SCR_014387) | IIDP | data or information resource, organization portal, portal, resource | The goal of the Integrated Islet Distribution Program (IIDP) is to work with the leading islet isolation centers in the U.S. to distribute high quality human islets to the diabetes research community, in order to advance scientific discoveries and translational medicine. | program, islet, distribution, diabetes |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources |
Diabetes | NIDDK | http://www.niddk.nih.gov/research-funding/research-resources/Pages/default.aspx | SCR_014387 | Integrated Islet Distribution Program | 2026-08-29 11:27:36 | 323 | ||||||
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Centers for Diabetes Translation Research Resource Report Resource Website 1+ mentions |
Centers for Diabetes Translation Research (RRID:SCR_015149) | data or information resource, disease-related portal, organization portal, portal, resource, topical portal | Centers that are part of an integrated program whose cores support and enhance diabetes type II translation research. The CDTRs aim to enhance the efficiency, productivity, effectiveness and multidisciplinary nature of diabetes translation research. | diabetes type ii, diabetes research, translation |
is listed by: NIDDK Information Network (dkNET) is affiliated with: Vanderbilt Center for Diabetes Translation Research is affiliated with: New York Regional Center for Diabetes Translation Research is affiliated with: Chicago Center for Diabetes Translation Research is affiliated with: Georgia Center for Diabetes Translation Research is affiliated with: Michigan Center for Diabetes Translational Research is affiliated with: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases has organization facet: Chicago Center for Diabetes Translation Research has organization facet: New York Regional Center for Diabetes Translation Research has organization facet: Georgia Center for Diabetes Translation Research has organization facet: Health Delivery Systems Center for Diabetes Translational Research has organization facet: Michigan Center for Diabetes Translational Research has organization facet: Vanderbilt Center for Diabetes Translation Research has organization facet: Washington University Center for Diabetes Translation Research |
Diabetes | NIDDK P30RFA-DK15-003 | Available to the research community | SCR_015149 | 2026-08-29 11:28:05 | 1 | ||||||||
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Cystic Fibrosis Center - University of California San Francisco Resource Report Resource Website |
Cystic Fibrosis Center - University of California San Francisco (RRID:SCR_015398) | access service resource, data or information resource, disease-related portal, portal, resource, service resource, topical portal | Research center that focuses on developing novel therapies for cystic fibrosis, enhancing research projects examining the mechanisms of the disease, and developing new small-molecule therapies that can be translated into the clinic. | cystic fibrosis therapy, cystic fibrosis mechanism, cystic fibrosis research, small molecule therapy |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of California at San Francisco; California; USA is organization facet of: Cystic Fibrosis Research and Translation Centers |
Cystic Fibrosis | NIDDK P30DK072517 | Available to the research community | SCR_015398 | 2026-08-29 11:27:38 | 0 | ||||||||
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SigCom LINCS Resource Report Resource Website 1+ mentions |
SigCom LINCS (RRID:SCR_022275) | data access protocol, software resource, web service | Web server that serves over million gene expression signatures processed, analyzed, and visualized from LINCS, GTEx, and GEO. Data and metadata search engine for gene expression signatures. | FAIR data, data and metadata search engine, gene expression signatures, gene expression signature processed, analyzed, and visualized, LINCS, GTEx, GEO, gene expression signatures, | NHLBI U54HL127624; NIDDK R01DK131525; NIH Office of the Director OT2OD030160 |
PMID:35524556 | Free, Freely available | https://github.com/MaayanLab/sigcom-lincs | SCR_022275 | SigCom Library of Integrated Network-based Cellular Signatures | 2026-08-29 11:27:55 | 8 | |||||||
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SpiecEasi Resource Report Resource Website 10+ mentions |
SpiecEasi (RRID:SCR_022712) | SpiecEasi | data analysis software, data processing software, software application, software resource | Software R package for microbiome network analysis. Used for inference of microbial ecological networks from amplicon sequencing datasets. Combines data transformations developed for compositional data analysis with graphical model inference framework that assumes underlying ecological association network is sparse. | microbiome network analysis, amplicon sequencing datasets, microbial ecological networks inference | NIAID AI007180; NIDDK DK103358; NIGMS GM63270; Simons Foundation |
PMID:25950956 | Free, Available for download, Freely available | SCR_022712 | SParse InversE Covariance Estimation for Ecological Association Inference | 2026-08-29 11:28:20 | 20 | |||||||
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PICRUSt2 Resource Report Resource Website 500+ mentions |
PICRUSt2 (RRID:SCR_022647) | simulation software, software application, software resource | Software for predicting functional abundances based only on marker gene sequences.Used for prediction of metagenome functions. Contains updated and larger database of gene families and reference genomes, provides interoperability with any operational taxonomic unit (OTU)-picking or denoising algorithm, and enables phenotype predictions. Allows addition of custom reference databases. | predicting functional abundances, marker gene sequences, metagenome functions prediction | is related to: PICRUSt | GlaxoSmithKline ; NIDDK R24DK110499; NIDDK U54DK102557; NSERC ; NSF IOS CAREER 1942647 |
PMID:32483366 | Free, Available for download, Freely available | https://github.com/picrust/picrust2 | SCR_022647 | Phylogenetic Investigation of Communities by Reconstruction of Unobserved States | 2026-08-29 11:28:05 | 583 | ||||||
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University of Colorado Diabetes Research Center Resource Report Resource Website |
University of Colorado Diabetes Research Center (RRID:SCR_022897) | nonprofit organization | Center to facilitate diabetes research at University of Colorado by integrating interdisciplinary basic, translational, and clinical diabetes research base; providing infrastructure and resources that are indispensable for continued discovery and progress towards diabetes research and developing improved prediction and disease prevention;providing P&F and enrichment programs to support DRC investigators and their trainees, and recruit new and young investigators into diabetes research. | diabetes, clinical diabetes research, infrastructure and resources |
is related to: University of Colorado Denver; Colorado; USA is related to: University of Colorado Anschutz Medical Campus Diabetes Research Center Disease Modeling Core Facility is related to: University of Colorado Anschutz Medical Campus Diabetes Research Center Clinical Resource Core Facility is related to: University of Colorado Anschutz Medical Campus Diabetes Research Center Tissue Procurement and Processing Core Facility is related to: University of Colorado Anschutz Medical Campus Diabetes Research Center Cell and Tissue Analysis Core Facility has parent organization: University of Colorado; Colorado; USA |
NIDDK P30DK116073 | SCR_022897 | 2026-08-29 11:28:12 | 0 | ||||||||||
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North Carolina Diabetes Research Center Resource Report Resource Website |
North Carolina Diabetes Research Center (RRID:SCR_022896) | NCDRC | nonprofit organization | Interactive regional diabetes research community across four premiere research institutions in North Carolina, who currently garner over $70 million annually for support of their diabetes research: Duke University (Duke), The University of North Carolina at Chapel Hill (UNC), Wake Forest School of Medicine (WF), and North Carolina A&T State University (NC A&T State). NCDRC supports Research Cores that represent unique strengths at each institution. | Interactive regional diabetes research community |
is parent organization of: North Carolina Diabetes Research Center Metabolomics Core Facility is parent organization of: North Carolina Diabetes Research Center Advanced Clinical Study Methods Core Facility is parent organization of: North Carolina Diabetes Research Center Genomics and Proteomics Core Facility |
NIDDK P30DK124723 | SCR_022896 | 2026-08-29 11:28:12 | 0 | |||||||||
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Exon Array Browser Resource Report Resource Website 1+ mentions |
Exon Array Browser (RRID:SCR_008712) | Exon Array Browser | data or information resource, database, service resource | Transcriptome database of acutely isolated purified astrocytes, neurons, and oligodendrocytes. Provides improved cell-type-specific markers for better understanding of neural development, function, and disease. | mature mouse, forebrain, transcriptome, astrocyte, neuron, oligodendrocyte, brain development, brain function, molecular neuroanatomy resource, visualization | has parent organization: Stanford University; Stanford; California | NINDS R01NS045621; NEI R01EY10257; NEI EY07033; Medical Scientist Training Program Grant MSTP GM07365; Australian National Health and Medical Research Council CJ Martin Fellowship 400438; NIDDK DK54388; NCI CA095030 |
PMID:18171944 | Free, Freely available | nlx_143565 | SCR_008712 | 2026-08-29 11:30:27 | 1 | ||||||
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University of Chicago Digestive Diseases Research Core Center Resource Report Resource Website 1+ mentions |
University of Chicago Digestive Diseases Research Core Center (RRID:SCR_015601) | DDRCC | data or information resource, organization portal, portal, training resource | Center whose goals include fostering collaboration among basic and clinical investigators, facilitating the use of new technologies in the study of treatment of digestive diseases, and providing education and training for improved treatment and diagnosis. | DDRCC, digestive disease, uchicago |
is listed by: NIDDK Information Network (dkNET) is parent organization of: University of Chicago Digestive Diseases Research Core Center Integrated Translational Research Core is parent organization of: University of Chicago Digestive Diseases Research Core Center Administrative Core is parent organization of: University of Chicago Digestive Diseases Research Core Center Host-Microbe Core is parent organization of: University of Chicago Digestive Diseases Research Core Center Tissue and Cell Imaging Core is parent organization of: University of Chicago Digestive Diseases Research Core Center Tissue Engineering and Cell Models Core has organization facet: University of Chicago Digestive Diseases Research Core Center Administrative Core has organization facet: University of Chicago Digestive Diseases Research Core Center Integrated Translational Research Core has organization facet: University of Chicago Digestive Diseases Research Core Center Tissue Engineering and Cell Models Core has organization facet: University of Chicago Digestive Diseases Research Core Center Host-Microbe Core has organization facet: University of Chicago Digestive Diseases Research Core Center Tissue and Cell Imaging Core is organization facet of: Digestive Disease Centers |
digestive disease | NIDDK P30 DK042086 | Available to the research community | SCR_015601 | 2026-08-29 11:28:25 | 1 | |||||||
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Diabetes Prevention Program Resource Report Resource Website |
Diabetes Prevention Program (RRID:SCR_001501) | DPP | bibliography, clinical trial, data or information resource, database, resource | Multicenter clinical research study aimed at discovering whether modest weight loss through dietary changes and increased physical activity or treatment with the oral diabetes drug metformin (Glucophage) could prevent or delay the onset of type 2 diabetes in study participants. At the beginning of the DPP, all 3,234 study participants were overweight and had blood glucose levels higher than normal but not high enough for a diagnosis of diabetesa condition called prediabetes. In addition, 45 percent of the participants were from minority groups-African American, Alaska Native, American Indian, Asian American, Hispanic/Latino, or Pacific Islander-at increased risk of developing diabetes. The DPP found that participants who lost a modest amount of weight through dietary changes and increased physical activity sharply reduced their chances of developing diabetes. Taking metformin also reduced risk, although less dramatically. In the DPP, participants from 27 clinical centers around the United States were randomly divided into different treatment groups. The first group, called the lifestyle intervention group, received intensive training in diet, physical activity, and behavior modification. By eating less fat and fewer calories and exercising for a total of 150 minutes a week, they aimed to lose 7 percent of their body weight and maintain that loss. The second group took 850 mg of metformin twice a day. The third group received placebo pills instead of metformin. The metformin and placebo groups also received information about diet and exercise but no intensive motivational counseling. A fourth group was treated with the drug troglitazone (Rezulin), but this part of the study was discontinued after researchers discovered that troglitazone can cause serious liver damage. The participants in this group were followed but not included as one of the intervention groups. In the years since the DPP was completed, further analyses of DPP data continue to yield important insights into the value of lifestyle changes in helping people prevent type 2 diabetes and associated conditions. For example, one analysis confirmed that DPP participants carrying two copies of a gene variant, or mutation, that significantly increased their risk of developing diabetes benefited from lifestyle changes as much as or more than those without the gene variant. Another analysis found that weight loss was the main predictor of reduced risk for developing diabetes in DPP lifestyle intervention group participants. The authors concluded that diabetes risk reduction efforts should focus on weight loss, which is helped by increased exercise. | prevention, lifestyle, metformin, intervention, dietary change, physical activity, minority, african-american, alaska native, american indian, asian american, hispanic, latino, pacific islander, male, female, slide, adult human, late adult human, dna |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Central Repository has parent organization: George Washington University; Washington D.C.; USA |
Type 2 diabetes, Prediabetes, Overweight, Non-insulin-dependent diabetes mellitus | NIDDK 1ZIADK075078-04 | Free, Freely available | nlx_152799 | SCR_001501 | 2026-08-29 11:28:17 | 0 | ||||||
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TIGER Data Portal Resource Report Resource Website 10+ mentions |
TIGER Data Portal (RRID:SCR_023626) | data or information resource, disease-related portal, portal, topical portal | Resource enables integrative exploration of genetic and epigenetic basis of development of Type 2 Diabetes, together with other associated functional, molecular and clinical data, centered in biology and role of pancreatic beta cells.The gene expression regulatory variation landscape of human pancreatic islets. | Type 2 Diabetes, genetic and epigenetic, functional data, molecular data, clinical data, pancreatic beta cells. | is related to: T2DSystems | Type 2 Diabetes | American Diabetes Association Innovative and Clinical Translational Award ; European Union Horizon 2020 ; NIDDK U01 DK085545; NIDDK U01 DK105535; Research England ; Spanish government ; Swiss State Secretariat for Education‚ Research and Innovation ; Wellcome Trust |
PMID:34644572 | SCR_023626 | Translational Human Pancreatic Islet Genotype Tissue-Expression Resource | 2026-08-29 11:28:01 | 23 | |||||||
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NIDDK Inflammatory Bowel Disease Genetics Consortium Resource Report Resource Website 1+ mentions |
NIDDK Inflammatory Bowel Disease Genetics Consortium (RRID:SCR_001461) | IBDGC, NIDDKIBDGC | biomaterial supply resource, cell repository, material resource | Repository of biospecimen and phenotype data collected from Crohn's disease and ulcerative colitis cases and controls recruited at six sites throughout North America that are available to the scientific community. Phenotyping is performed using a standardized protocol, and lymphoblastoid cell lines are established for each subject. Phenotype data for each subject are collected by the Consortium's Data Coordinating Center (DCC), and phenotype data for all subjects with DNA samples are available. The resulting DNA samples have already been utilized by the Consortium to complete various association studies, including genome-wide association studies using dense genotyping arrays. Researchers can obtain DNA samples and phenotype, genotype, and pedigree data through the Data Repository. GWAS data must be requested through dbGAP. The IBDGC is involved with independent genetic research studies and actively works with members of the IBD and genetic communities on collaborative projects. They are also members of the International IBD Genetics Consortium. Phenotype Tools: The Consortium Phenotype Committee, led by Dr. Hillary Steinhart designed and validated paper forms to collect extensive phenotype data on Crohn's Disease and ulcerative colitis. Consortium phenotype tools are available for use by non-Consortium members. | dna, cell line, serum, lymphocyte, lymphoblastoid cell line, gene, loci, genetic analysis, blood, phenotype, genome-wide association study, genotype, pedigree, metadata standard, genotyping array |
uses: NCBI database of Genotypes and Phenotypes (dbGap) is listed by: One Mind Biospecimen Bank Listing is listed by: NIDDK Information Network (dkNET) has parent organization: Yale School of Medicine; Connecticut; USA |
Inflammatory Bowel Disease, Crohn's disease, Ulcerative colitis, Control, Family member | NIDDK U01 DK062429 | Free, Freely Available | nlx_152706 | http://medicine.yale.edu/intmed/ibdgc/ | SCR_001461 | IBD Genetics Consortium, NIDDKIBD Genetics Consortium, Inflammatory Bowel Disease Genetic Consortium | 2026-08-29 11:28:28 | 3 | ||||
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Islet Cell Resource Centers Resource Report Resource Website 100+ mentions |
Islet Cell Resource Centers (RRID:SCR_002806) | ICR | biomaterial supply resource, cell repository, material resource | Group of 10 academic laboratories provide pancreatic islets of cGMP-quality to eligible investigators for use in FDA approved, IRB-approved transplantation protocols in which isolated human islets are transplanted into qualified patients afflicted with type 1 diabetes mellitus; optimize the harvest, purification, function, storage, and shipment of islets while developing tests that characterize the quality and predict the effectiveness of islets transplanted into patients with diabetes mellitus; and provide pancreatic islets for basic science studies. The centers are electronically linked through an Administrative and Bioinformatics Coordinating Center (ABCC). The ABCC manages a system with objectively defined criteria that establishes the order of priority for islet distribution. It also provides database and other informatics to track the utilization of pancreata and all distributed clinical grade islets for transplant and basic research, and supports the Islet Cell Resource Centers Consortium so that the research community has a single entry point to the program. Qualified researchers from domestic institutions may request islets by submitting a written application to the director of the ABCC. The ICRs will distribute Islets as appropriate for either clinical or basic science protocol use to eligible investigators who have received a favorable review and subsequent approval by the ICR Steering Committee (SC). The Administrative and Bioinformatics Coordinating Center (ABCC) manages the distribution according to a priority list. The ABCC will give preference to investigators who have peer-reviewed, NIH-funded research support. | pancreatic islet, clinical |
is listed by: One Mind Biospecimen Bank Listing is related to: One Mind Biospecimen Bank Listing is related to: NIDDK Information Network (dkNET) |
Type 1 diabetes, Diabetes | NIDDK ; Juvenile Diabetes Research Foundation International ; NCRR 1 U42 RR17673 |
Free, Freely available, Available for download | nif-0000-25418 | SCR_002806 | 2026-08-29 11:28:32 | 123 | ||||||
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Beta Cell Biology Consortium Resource Report Resource Website 50+ mentions |
Beta Cell Biology Consortium (RRID:SCR_005136) | BCBC | biomaterial supply resource, cell repository, material resource | THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented on August 1, 2015. Consortium that aims to facilitate interdisciplinary collaborations to advance the understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. They are responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort. The scientific goals for the BCBC are to: * Use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem / progenitor cells for use in cell-replacement therapies for diabetes, * Determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients, * Determine how to reprogram progenitor / adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes, and * Investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities should accelerate the pace of major new discoveries and progress within the field of beta cell biology. | RIN, Resource Information Network, pancreatic islet, mouse, beta cell, pancreas, pancreatic development, embryonic stem cell, cell line, genomics, antibody, adenovirus, functional genomics, mouse embryonic stem cell line, mouse strain, protocol, embryonic stem cell line, data sharing, data set, gene expression, gene, pancreatic islet development, pancreatic islet function, basic science, basic research, cell reprogramming, cell regeneration, cell replacement, RRID Community Authority |
is used by: NIF Data Federation is used by: Integrated Animals is used by: NIDDK Information Network (dkNET) is listed by: One Mind Biospecimen Bank Listing is listed by: re3data.org is listed by: Consortia-pedia is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources is listed by: Resource Information Network is related to: dkCOIN is related to: Karolinska Institute; Stockholm; Sweden is related to: University of California at Los Angeles; California; USA is related to: Stanford University; Stanford; California is related to: University of Massachusetts Medical School; Massachusetts; USA is related to: Hebrew University Hadassah Medical School; Jerusalem; Israel is related to: Philipps-University Marburg; Marburg; Germany is related to: Imperial College London; London; United Kingdom is related to: Childrens Hospital of Philadelphia - Research Institute; Pennsylvania; USA is related to: Icahn School of Medicine at Mount Sinai; New York; USA is related to: University of California at San Francisco; California; USA is related to: Massachusetts Institute of Technology; Massachusetts; USA; is related to: Hadassah Medical Center; Jerusalem; Israel is related to: DanStem is related to: Oregon Health and Science University; Oregon; USA is related to: Vanderbilt University; Tennessee; USA is related to: University of Chicago; Illinois; USA is related to: University of Massachusetts; Massachusetts; USA is related to: University of Colorado Boulder; Colorado; USA is related to: Vrije Universiteit Brussel; Brussels; Belgium is related to: University of Geneva; Geneva; Switzerland is related to: University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA is related to: McEwen Centre for Regenerative Medicine is related to: Seattle Childrens Research Institute; Washington; USA is related to: Columbia University; New York; USA is related to: University of Texas Southwestern Medical Center; Texas; USA is related to: Hagedorn Research Institute; Gentofte; Denmark is related to: Howard Hughes Medical Institute is related to: Northwestern University; Illinois; USA is related to: CAMRD is related to: French National Center for Scientific Research is related to: University of California at San Diego; California; USA is related to: University of Pittsburgh; Pennsylvania; USA is related to: University of Copenhagen; Copenhagen; Denmark is related to: Jackson Laboratory is related to: Max Planck Institute for Heart and Lung Research; Bad Nauheim; Germany is related to: Indiana University; Indiana; USA is related to: University of Toronto; Ontario; Canada is related to: Harvard University; Cambridge; United States is related to: Harvard Medical School; Massachusetts; USA is related to: Integrated Manually Extracted Annotation has parent organization: Vanderbilt University; Tennessee; USA is parent organization of: Beta Cell Genomics Ontology |
Type 1 diabetes, Diabetes | NIDDK DK-01-014; NIDDK DK-01-17; NIDDK DK-01-18; NIDDK DK-09-011 |
THIS RESOURCE IS NO LONGER IN SERVICE | nlx_144143 | SCR_005136 | 2026-08-29 11:28:40 | 60 | ||||||
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Type 1 Diabetes Preclinical Testing Program Resource Report Resource Website |
Type 1 Diabetes Preclinical Testing Program (RRID:SCR_006861) | T1D-PTP, NIDDKT1D-PTP | resource, service resource | THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. Investigator access is provided to the established facilities and expertise needed to extend, enhance and validate preclinical studies of promising new therapeutics in cases where additional preclinical testing is needed to validate potential therapies under disease-specific conditions and in multiple animal models before therapeutics can enter the Type 1 Diabetes Rapid Access to Intervention Development (T1D-RAID) development pipeline. The T1D-RAID program provides resources for pre-clinical development of drugs, natural products, and biologics that will be tested as new therapeutics in type 1 diabetes clinical trials. The T1D-RAID program is not currently accepting applications. The T1D-PTP program currently supports two contracts, which are separate from each other and from the T1D-RAID NCI contract resources, to assist in preclinical development of therapeutics for T1D: * Agents to be tested for Preclinical Efficacy in Prevention or Reversal of Type 1 Diabetes in Rodent Models. Type 1 Diabetes Preclinical Testing Program (T1D-PTP) (NOT-DK-09-006) * Needs for Preclinical Efficacy Testing of Promising Agents to Prevent or Reverse Diabetic Complications (NOT-DK-09-009) The T1D-RAID and T1D-PTP are programs intended to remove the most common barriers to progress in identification and development of new therapies for Type 1 Diabetes. The common goal of these programs is to support and provide for the preclinical work necessary to obtain proof of principle establishing that a new molecule or novel approach will be a viable candidate for expanded clinical evaluation. | testing, therapeutic, clinical, drug, preclinical, therapy, drug development, high-throughput screening, animal model, formulation, pharmacology, toxicology |
is related to: Type 1 Diabetes - Rapid Access to Intervention Development is related to: NIDDK Information Network (dkNET) has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases |
Type 1 diabetes, Diabetes | NIDDK | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_152741 | SCR_006861 | Type 1 Diabetes Preclinical Testing Program (T1D-PtP), NIDDKType 1 Diabetes Preclinical Testing Program | 2026-08-29 11:31:56 | 0 | |||||
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Functional Dyspepsia Treatment Trial Resource Report Resource Website |
Functional Dyspepsia Treatment Trial (RRID:SCR_006691) | FDTT | clinical trial, resource | Multi-center, randomized, placebo-controlled trial evaluating the tricyclic antidepressant, amitriptyline and the selective serotonin reuptake inhibitor (SSRI), escitalopram to placebo in patients with functional dyspepsia. The purpose of this study is to determine whether amitriptyline and escitalopram are more efficacious than placebo in relief of the symptoms of functional dyspepsia, adjusting for psychological and psychiatric co-morbidities. | antidepressant, amitriptyline, selective serotonin reuptake inhibitor, escitalopram, placebo |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources has parent organization: ClinicalTrials.gov |
Functional dyspepsia | NIDDK | PMID:22343090 | nlx_152830 | SCR_006691 | Antidepressant Therapy for Functional Dyspepsia, Functional Dyspepsia Treatment Trial (FDTT) | 2026-08-29 11:31:56 | 0 |
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