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https://www.olympus-lifescience.com/data/olympusmicro/brochures/pdfs/ix71.pdf?rev=EABE
Research inverted system microscope. Olympus IX2 inverted microscope combined with UIS2 optical system. Used for live cell experiments.
Proper citation: Olympus: IX71 Microscope (RRID:SCR_022185) Copy
http://www.pstnet.com/software.cfm?ID=96
Designed for use in an MRI simulator, MoTrak software uses Ascension Technology?s Flock of Birds. The sensor attaches to the subject?s head and determines the position of the head in space relative to the transmitter. The sensor records angular rotations as well as positional displacements from an initially calibrated position. This information is displayed and logged by the program in real-time, allowing observation of head motion in an MRI simulator. In the simulator, the participant can simultaneously be habituated to the MRI environment, while being trained to remain still via feedback from the MoTrak system.
Proper citation: MoTrak Head Motion Tracking System (RRID:SCR_009607) Copy
Griffin (G-protein-receptor interacting feature finding instrument) is a high-throughput system to predict GPCR - G-protein coupling selectively with the input of GPCR sequence and ligand molecular weight. This system consists of two parts: 1) HMM section using family specific multiple alignment of GPCRs, 2) SVM section using physico-chemical feature vectors in GPCR sequence. G-protein coupled receptors (GPCR), which is composed of seven transmembrane helices, play a role as interface of signal transduction. The external stimulation for GPCR, induce the coupling with G-protein (Gi/o, Gq/11, Gs, G12/13) followed by different kinds of signal transduction to inner cell. About half of distributed drugs are intending to control this GPCR - G-protein binding system, and therefore this system is important research target for the development of effective drug. For this purpose, it is necessary to monitor, effectively and comprehensively, of the activation of G-protein by identifying ligand combined with GPCR. Since, at present, it is difficult to construct such biochemical experiment system, if the answers for experimental results can be prepared beforehand by using bioinformatics techniques, large progress is brought to G-protein related drug design. Previous works for predicting GPCR-G protein coupling selectivity are using sequence pattern search, statistical models, and HMM representations showed high sensitivity of predictions. However, there are still no works that can predict with both high sensitivity and specificity. In this work we extracted comprehensively the physico-chemical parameters of each part of ligand, GPCR and G-protein, and choose the parameters which have strong correlation with the coupling selectivity of G-protein. These parameters were put as a feature vector, used for GPCR classification based on SVM.
Proper citation: G protein receptor interaction feature finding instrument (RRID:SCR_008343) Copy
https://www.thermofisher.com/order/catalog/product/3730XL#/3730XL
96-capillary DNA analyzer that performs DNA fragment analysis applications such as microsatellites, AFLP, SNP analysis, mutation detection and traditional DNA sequencing. Has multiple automation features. Performs sequencing and fragment analysis applications including resequencing, microsatellite analysis, AFLP, LOH, SSCP, SNP screening and SNP validation.
Proper citation: Thermo Fisher: Applied Biosystems: 3730xl Capillary Genetic Sequencer (RRID:SCR_018059) Copy
Femto Pulse System separates large molecular weight DNA fragments and detects nucleic acids into femtogram range.Fragment analyzer that provides pulsed field power supply which allows large molecular weight DNA fragments to be separated and nucleic acids detected into femtogram range. Ability to separate high molecular weight DNA up to 165 kb and detect nucleic acids down to 50 fg per uL input concentration makes system ideal for long-read NGS QC, gDNA, small RNA, or cfDNA analysis from low concentration samples.
Proper citation: Agilent: Femto Pulse System (RRID:SCR_018058) Copy
https://www.thermofisher.com/order/catalog/product/3730S#/3730S
Medium to high throughput genetic analyzer that performs DNA fragment analysis applications such as microsatellites, AFLP, SNP analysis, mutation detection and traditional DNA sequencing. Upgradeable to 96 capillaries.
Proper citation: Thermo Fisher: Applied Biosystems: 3730 Genetic Analyzer (RRID:SCR_018052) Copy
Refridgerated centrifuge with 18 place capacity rotor that accomdates low to medium capacity in 1.5 or 2.0 mL tubes and Microtainer. Speed allows for standard molecular biology applications. Compact size and quiet operation.
Proper citation: Eppendorf: 5418 R Centrifuge (RRID:SCR_018050) Copy
Flow cytometry system that performs reliable performance, accuracy, and ease-of-use for clinical diagnostic services. System has 10 color capability, optical enhancements, and 4-3-3 configuration deliver high sensitivity and resolution for accurate results.
Proper citation: BD Biosciences: FACSCanto Flow Cytometer (RRID:SCR_018055) Copy
MRI system that performs preclinical and molecular MR imaging. MRI CryoProbe technology combined with ultra high field USR magnets deliver high spatial resolution in-vivo. Any small animal MR imaging application in life science, biomedical and preclinical research can be conducted.
Proper citation: Bruker: 9.4T Biospec Biospec Magnetic Resonance Imaging (RRID:SCR_018054) Copy
https://www.selectscience.net/products/zeiss-lsm-710-for-fluorescence-imaging/?prodID=84549#tab-2
Inverted microscope that enables confocal microscopy in cell and developmental biology.
Proper citation: Zeiss: LSM 710 Confocal Inverted Microscope (RRID:SCR_018063) Copy
https://www.biocompare.com/Product-Reviews/41153-LSM-510-META-From-Zeiss/
Versatile laser scanning confocal microscope system that is available in both upright or inverted format. Equipped with ICS-Optics. Selection of dry, water immersion and oil immersion objectives are available. ICS-Optics are infinity color corrected.
Proper citation: Zeiss: LSM 510 Confocal Microscope (RRID:SCR_018062) Copy
https://en.mgitech.cn/Uploads/Temp/file/20191231/5e0b086c38d24.pdf
Desktop sequencer developed by BGI. Using DNA nanoball and combinational probe anchor synthesis developed from Complete Genomics sequencing technologies, it generates short reads at large scale. BGI/MGI Sequencer.
Proper citation: BGI: BGISEQ-500 (RRID:SCR_017979) Copy
https://en.mgitech.cn/products/instruments_info/5/
Sequencer can generate 1-6Tb of high quality data per day, for wide range of applications including Whole Genome Sequencing, Deep Exome Sequencing, Epigenome Sequencing, Transcriptome Sequencing, and targeted panel projects. Powered by DNBSEQTM Technology, DNBSEQ-T7 makes sequencing more efficient and productive with advances in biochemical, fluidics, and optical systems. Detection and characterization of copy number variants based on whole-genome sequencing by MGI platforms.
Proper citation: MGI: DNBSEQ-T7 (RRID:SCR_017981) Copy
https://www.mscience.com.au/upload/pages/pacbio/pacbio_rs_ii_brochure.pdf
Sequencer by Pacific Biosciences. System allows scientists to generate finished genome assemblies, reveal and understand epigenomes, and characterize genomic variation. It achieves longest read lengths and highest consensus accuracy. Finishes microbial genomes and improves assembly of larger organisms with multi-kilobase reads and unbiased coverage regardless of GC content. No amplification is required.
Proper citation: PacBio: RS II Sequencing System (RRID:SCR_017988) Copy
https://nanoporetech.com/products/promethion
System offers real-time, long-read, direct DNA and RNA sequencing by Oxford Nanopore Technologies. System suitable for large scale projects such as population-scale sequencing or plant genomics, or for large scale service offerings. PromethION 24 and PromethION 48 systems offer ability to run 24 and 48 flow cells respectively. System allows on demand sequencing, using any flow cell at any time. Users can start and stop running individual experiments as required, or deploy multiple flow cells onto single experiments for greater speed or throughput.
Proper citation: Oxford: Nanopore Technologies: PromethION (RRID:SCR_017987) Copy
https://nanoporetech.com/products/gridion
Benchtop sequencing and analysis device designed to run and analyse up to five individually addressable MinION or Flongle Flow Cells by Oxford Nanopore Technologies. Good for labs with multiple projects that need advantages of nanopore sequencing: simple library preparation, real-time analysis and new biological insights from long reads.
Proper citation: NanoporeTech: GridION Mk1 (RRID:SCR_017986) Copy
https://en.mgitech.cn/products/instruments_info/2/
Sequencer developed by MGI Tech Co. Ltd. Next generation sequencing platform. Its sequencing principle relies on DNB and cPAS technologies also used in previous version of BGISEQ-500 device, but reagents for MGISEQ-2000 are refined and platform utilizes updated software. Built with new chip system that can flexibly support variety of different sequencing models.
Proper citation: MGI: DNBSEQ-G400 (RRID:SCR_017980) Copy
Paraffin embedding station that provides constant, reproducible paraffin flow at ten different flow rate settings. All instrument functions, including automatic starting time, are individually programmable at press of button. Compact dimensions, ease of operation, and high standards of convenience. Separately-heated paraffin dispensing system with integrated filter provides constant, reproducible paraffin flow at ten different flow rate settings.
Proper citation: Leica: EG1160 Embedding Station (RRID:SCR_018033) Copy
https://www.labx.com/item/molecular-devices-molecular-dynamics-storm-860-molecular/3896212
Multifunction phosphoimager fluorimager laser scanner that collects fluorescent or storage phosphor images from gels, membranes and phosphor screens. It is equipped with blue (450 nm) and red (635 nm) lasers, can scan at resolutions down to 50 microns. It is able to quantify radioactive gels for commonly used isotopes such as 32P, 33P, 125I, 35S, and 14C. There are three detection modes: phosphor screen mode, red/blue fluorescence, chemifluorescence.
Proper citation: Molecular Devices: Molecular Dynamics Storm 860 Molecular Imager (RRID:SCR_018032) Copy
https://www.pacb.com/blog/introducing-the-sequel-system-the-scalable-platform-for-smrt-sequencing/
Single Molecule, Real-Time sequencer by Pacific Biosciencies. System provides higher throughput, more scalability, reduced footprint and lower sequencing project costs compared to PacBi RS II System, while maintaining benefits of SMRT technology. Ideal for projects such as generating high quality, whole genome de novo assemblies for larger genomes, such as human, plants, and animals. Provides characterization of wide variety of genomic variation types, including those in complex regions not accessible with short-read or synthetic long-range sequencing technologies, while simultaneously revealing epigenetic information.
Proper citation: PacBio: Sequel System (RRID:SCR_017989) Copy
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