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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://cran.r-project.org/web/packages/metaMA/
Software R package for meta-analysis for microarrays. It combines either p-values or modified effect sizes from different studies to find differentially expressed genes.
Proper citation: metaMA (RRID:SCR_000408) Copy
Issue
https://cran.r-project.org/web/packages/adegenet/index.html
Software package dedicated to the handling of molecular marker data for multivariate analysis. This package is related to ADE4, a R package for multivariate analysis, graphics, phylogeny and spatial analysis. (entry from Genetic Analysis Software)
Proper citation: ADEGENET (RRID:SCR_000825) Copy
https://CRAN.R-project.org/package=brms
Software package implements Bayesian multilevel models in R using probabilistic programming language Stan.
Proper citation: brms (RRID:SCR_023862) Copy
https://cran.r-project.org/web/packages/lme4/index.html
Software R package. Fit linear and generalized linear mixed-effects models. The models and their components are represented using S4 classes and methods. The core computational algorithms are implemented using the 'Eigen' C++ library for numerical linear algebra and 'RcppEigen' "glue."
Proper citation: lme4 (RRID:SCR_015654) Copy
http://wpicr.wpic.pitt.edu/WPICCompGen/fdr/
Software application (entry from Genetic Analysis Software)
Proper citation: WEIGHTED FDR (RRID:SCR_013442) Copy
https://imdevsoftware.wordpress.com/imdev/
A software application of RExcel that integrates R into Excel as an embedded additon for omics tasks and analysis. It can be used specifically for tasks concerning multivariate data visualization, exploration, and analysis. imDev has interactive modules for dimensional reduction, prediction, feature selection, analysis of correlation, and generation of networked structures, all of which provide an integrated environment for systems level analysis of multivariate data.
Proper citation: imDEV (RRID:SCR_014674) Copy
https://cran.r-project.org/web/packages/devtools/index.html
Software tools to make developing R packages easier by providing R functions that simplify and expedite common tasks.
Proper citation: devtools (RRID:SCR_016961) Copy
https://cran.r-project.org/web/packages/viridis/vignettes/intro-to-viridis.html
Software package which brings to R color scales. Created for the Python matplotlib library.
Proper citation: viridis (RRID:SCR_016696) Copy
http://pbil.univ-lyon1.fr/software/mareymap/
Software application that is a meiotic recombination rate estimation program. (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: MAREYMAP (RRID:SCR_009066) Copy
http://research.nhgri.nih.gov/software/TRAP/
Software tool for determining a regression model of quantitative or binary trait variation when the number of possible genetic predictors is very large, considering only a moderate number of predictors at one time, using unrelated or family data. (entry from Genetic Analysis Software)
Proper citation: TRAP (RRID:SCR_009002) Copy
https://github.com/gaow/genetic-analysis-software/blob/master/pages/SIMULAPLOT.md
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 22, 2016. A tool designed to help visualize the joint effect of genes and continuous environmental covariates on complex human disease simulation models.
Proper citation: SIMULAPLOT (RRID:SCR_009079) Copy
http://www.stat.auckland.ac.nz/~browning/ccrel/ccrel.htm
Software program for case-control genetic analysis that takes relatedness between individuals into account. It will perform single-marker and haplotypic tests, however it will only work with SNP or other biallelic markers. (entry from Genetic Analysis Software)
Proper citation: CCREL (RRID:SCR_009142) Copy
http://www.sanger.ac.uk/resources/software/peer/
Software collection of Bayesian approaches to infer hidden determinants and their effects from gene expression profiles using factor analysis methods. Applications of PEER have * detected batch effects and experimental confounders * increased the number of expression QTL findings by threefold * allowed inference of intermediate cellular traits, such as transcription factor or pathway activations This project offers an efficient and versatile C++ implementation of the underlying algorithms with user-friendly interfaces to R and python.
Proper citation: PEER (RRID:SCR_009326) Copy
A Java Api for the visual analysis of large and complex pedigrees that provides all the necessary functionality for the interactive exploration of extended genealogies. Available packages are mostly focused on a static representation or cannot be added to an existing application; the goal of this open-source library is to provide an application program interface that enables the efficient construction of visual analytic applications for the analysis of family based data. (entry from Genetic Analysis Software)
Proper citation: PEDVIZAPI (RRID:SCR_009325) Copy
https://cran.r-project.org/web/packages/snp.plotter/index.html
An R package that creates publishable-quality plots of p-values using single SNP and/or haplotype data. Main features of the package include options to display a linkage disequilibrium (LD) plot and the ability to plot multiple sets of results simultaneously. Plots can be created using global and/or individual haplotype p-values along with single SNP p-values. Images are created as either Portable Document Format (PDF) or Encapsulated (EPS) files. (entry from Genetic Analysis Software)
Proper citation: R/SNP.PLOTTER (RRID:SCR_009376) Copy
https://cran.r-project.org/web/packages/rmetasim/index.html
An R package that uses an individual-based approach to simulate distributions of genotypes that result from arbitrary within and among population demographies (including extinction/recolonization). These distributions can be used to test new or existing population-genetics summary statistics or develop null distributions under various demographies. (entry from Genetic Analysis Software)
Proper citation: R/METASIM (RRID:SCR_009370) Copy
http://research.nhgri.nih.gov/ROMPrev/
Software tool for testing for association between polymorphisms and quantitative traits, as well as estimating trait heritability and locus-specific heritability using family data. (entry from Genetic Analysis Software)
Proper citation: ROMPREV (RRID:SCR_009361) Copy
http://wpicr.wpic.pitt.edu/WPICCompGen/genomic_control/genomic_control.htm
Software application where GC implements the genomic control models. GCF implements the basic Genomic Control approach, but adjusts the p-values for uncertainty in the estimated effect of substructure. This approach is preferable if a large number of tests will be evaluated because it provides a more accurrate assessment of the significance level for small p-values. (entry from Genetic Analysis Software)
Proper citation: GC/GCF (RRID:SCR_009075) Copy
http://wpicr.wpic.pitt.edu/WPICCompGen/newcovibd/covibd.htm
Software application that refines linkage analysis of affected sibpairs by considering attributes or environmental exposures thought to affect disease liability. This refinement utilizes a mixture model in which a disease mutation segregates in only a fraction of the sibships, with the rest of the sibships unlinked. Covariate information is used to predict membership within the two groups corresponding to the linked and unlinked sibships. The pre-clustering model uses covariate information to first form two probabilistic clusters and then tests for excess IBD-sharing in the clusters. The Cov-IBD model determines probabilistic group membership by joint consideration of covariate and IBD values. (entry from Genetic Analysis Software)
Proper citation: COVIBD (RRID:SCR_009155) Copy
https://cran.r-project.org/package=tsne
Softare R package as implementation of the t-SNE algorithm.
Proper citation: tsne (RRID:SCR_024305) Copy
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