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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
Tree and reticulogram REConstruction
 
Resource Report
Resource Website
10+ mentions
Tree and reticulogram REConstruction (RRID:SCR_004497) T-REX analysis service resource, data analysis service, production service resource, service resource, software resource A web server dedicated to the reconstruction of phylogenetic trees, reticulation networks and to the inference of horizontal gene transfer (HGT) events. phylogenetic tree, analysis, visualization, network, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Quebec in Montreal; Quebec; Canada
PMID:22675075 biotools:t-rex, OMICS_04264 https://bio.tools/t-rex SCR_004497 SciCrunch Registry Trex-online 2026-10-10 12:37:14 33
Transporter Classification Database
 
Resource Report
Resource Website
100+ mentions
Transporter Classification Database (RRID:SCR_004490) TCDB, TC analysis service resource, data analysis service, data analysis software, data or information resource, data processing software, data repository, database, production service resource, service resource, software application, software resource, source code, storage service resource Curated, relational database containing sequence, classification, structural, functional and evolutionary information about transport systems from variety of living organisms based on IUBMB-approved transporter classification (TC) system. Descriptions, TC numbers, and examples of over 600 families of transport proteins are provided. TC system is analogous to Enzyme Commission (EC) system for classification of enzymes, except that it incorporates both functional and phylogenetic information. TCDB users may submit their own sequenced proteins and descriptions for inclusion into database. The software tools used are all freely available for download. These programs are used for analysis of Protein and DNA sequences. Programs require UNIX server to run. membrane transport, protein sequence, transporter, bio.tools, FASEB list is recommended by: National Library of Medicine
is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at San Diego; California; USA
NIGMS GM1077402 PMID:19022853
PMID:16381841
Free, Freely available nlx_47724, biotools:tcdb https://bio.tools/tcdb SCR_004490 SciCrunch Registry Transporter Classification Database 2026-10-10 12:36:49 343
Distributed String Mining Framework
 
Resource Report
Resource Website
1+ mentions
Distributed String Mining Framework (RRID:SCR_004736) dsm-framework software resource Software package providing distributed string mining for High-Throughput Sequencing data that provides a content-based exploration and retrieval method for whole metagenome sequencing samples. gpu/cuda, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24845653 GNU General Public License, v2 or greater biotools:dsm, OMICS_04171 https://bio.tools/dsm SCR_004736 SciCrunch Registry 2026-10-10 12:36:52 1
DELLY
 
Resource Report
Resource Website
500+ mentions
DELLY (RRID:SCR_004603) DELLY software resource Integrated structural variant prediction software that can detect deletions, tandem duplications, inversions and translocations at single-nucleotide resolution in short-read massively parallel sequencing data. It uses paired-ends and split-reads to sensitively and accurately delineate genomic rearrangements throughout genome. structural variant, genomic rearrangement, deletion, tandem duplication, inversion, translocation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: European Molecular Biology Laboratory
PMID:22962449
DOI:10.1093/bioinformatics/bts378
OMICS_00313, biotools:delly2 https://bio.tools/delly2, https://github.com/dellytools/delly/, https://sources.debian.org/src/delly/ SCR_004603 SciCrunch Registry DELLY, Structural variant discovery by integrated paired-end and split-read analysis 2026-10-10 12:36:51 639
Philius
 
Resource Report
Resource Website
Philius (RRID:SCR_004625) Philius analysis service resource, data analysis service, production service resource, service resource, software resource Web server that predicts protein transmembrane topology and signal peptides. Hidden Markov models (HMM) have been successfully applied to the tasks of transmembrane protein topology prediction and signal peptide prediction. They expand upon this work by making use of the more powerful class of dynamic Bayesian networks (DBN). Their model, Philius, is inspired by a previously published HMM, Phobius, and combines a signal peptide sub-model with a transmembrane sub-model. They introduce a two-stage DBN decoder which combines the power of posterior decoding with the grammar constraints of Viterbi-style decoding. Philius also provides protein type, segment, and topology confidence metrics to aid in the interpretation of the predictions. hidden markov model, protein type, segment, topology, confidence metric, prediction, protein, transmembrane, signal peptide, peptide, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Washington; Seattle; USA
PMID:18989393 nlx_62426, biotools:philius https://bio.tools/philius SCR_004625 SciCrunch Registry 2026-10-10 12:37:03 0
MetaPhyler
 
Resource Report
Resource Website
10+ mentions
MetaPhyler (RRID:SCR_004848) software resource A taxonomic classifier for metagenomic shotgun reads, which uses phylogenetic marker genes as a taxonomic reference. The classifier, based on BLAST, uses different thresholds (automatically learned from the reference database) for each combination of taxonomic rank, reference gene, and sequence length. The reference database includes marker genes from all complete genomes, several draft genomes and the NCBI nr protein database. metagenome, classification, sequence, taxonomy, genome, microbiome, bio.tools is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Maryland; Maryland; USA
PMID:21989143 Acknowledgement requested, Available for download OMICS_01455, biotools:metaphyler https://bio.tools/metaphyler SCR_004848 SciCrunch Registry MetaPhyler - Estimating Bacterial Composition from Metagenomic Sequences 2026-10-10 12:37:06 11
hyfi: software suite for binding site search
 
Resource Report
Resource Website
hyfi: software suite for binding site search (RRID:SCR_004884) software resource This collection of software is designed to rapidly identify identifies primer and microarray probe binding sites for a query sequence in genomic DNA. This software suite has four main programs:1. A program for indexing a sequence file to speed up the binding site search. 2. A program for retrieving the binding sites of a query sequence. 3. A program for identifying sites where PCR primers could co-operate to exponentially amplify a sequence 4. A program for analyzing a set of binding sites to tailor the search for different reaction conditions. This software is implemented in C. bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Washington; Seattle; USA
PMID:16873493 nlx_85657, biotools:hyfi https://bio.tools/hyfi SCR_004884 SciCrunch Registry Hyfi 2026-10-10 12:36:55 0
MetaPhlAn
 
Resource Report
Resource Website
500+ mentions
MetaPhlAn (RRID:SCR_004915) data analysis resource, data analysis software, data processing software, sequence analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Computational tool for profiling the composition of microbial communities from metagenomic shotgun sequencing data. It relies on unique clade-specific marker genes identified from reference genomes. microbial community, microbial composition, microbial genome, microbial sequence is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: Debian
has parent organization: Bitbucket
has parent organization: Harvard T.H. Chan School of Public Health
PMID:22688413
DOI:10.1038/nmeth.3589
OMICS_02286 http://huttenhower.sph.harvard.edu/metaphlan https://bitbucket.org/nsegata/metaphlan/, https://sources.debian.org/src/metaphlan2/ SCR_004915 SciCrunch Registry MetaPhlAn, Metagenomic Phylogenetic Analysis, MetaPhlAn version 2, MetaPhlAn - Metagenomic Phylogenetic Analysis, MetaPhlAn v2 2026-10-10 12:37:25 645
USeq
 
Resource Report
Resource Website
100+ mentions
USeq (RRID:SCR_004753) USeq software resource A collection of software tools for for both low and high level analysis of next generation, ultra high throughput signature sequencing data from the Solexa, SOLiD, and 454 platforms. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
OMICS_00499, biotools:useq https://bio.tools/useq SCR_004753 SciCrunch Registry 2026-10-10 12:37:20 131
NCBI BLAST
 
Resource Report
Resource Website
10000+ mentions
NCBI BLAST (RRID:SCR_004870) BLAST data access protocol, data analysis software, data processing software, sequence analysis software, software application, software resource, web service Web search tool to find regions of similarity between biological sequences. Program compares nucleotide or protein sequences to sequence databases and calculates statistical significance. Used for identifying homologous sequences. genome, similarity, sequence, nucleotide, protein, gene, data, bio.tools is used by: MITE-Tracker
is used by: Cello2Go
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: G-BLASTN
is related to: genBlastA
has parent organization: NCBI
is required by: RelocaTE
works with: Whole Genome Shotgun (WGS) Project
works with: BLASTClust
works with: MOLE-BLAST
works with: Genotyping
National Library of Medicine PMID:16845079
PMID:18440982
Free, Freely available, Tutorial available OMICS_01436, nlx_84530, biotools:blast http://blast.ncbi.nlm.nih.gov, https://bio.tools/blast, https://sources.debian.org/src/ncbi-blast+/ SCR_004870 SciCrunch Registry NCBI Basic Local Alignment Search Tool, NCBI BLAST, Basic Local Alignment Search Tool, BLAST 2026-10-10 12:36:55 17718
miRNAKey
 
Resource Report
Resource Website
1+ mentions
miRNAKey (RRID:SCR_004813) miRNAKey software resource A software pipeline for the analysis of microRNA Deep Sequencing data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:20801911 OMICS_00364, biotools:mirnakey https://bio.tools/mirnakey SCR_004813 SciCrunch Registry 2026-10-10 12:37:02 6
SVMerge
 
Resource Report
Resource Website
10+ mentions
SVMerge (RRID:SCR_004777) SVMerge software resource Software pipeline to detect structural variants (SVs) by integrating calls from several existing SV callers, which are then validated and the breakpoints refined using local de novo assembly. The output is in BED format allowing for easy downstream analysis or viewing in a genome browser. It is modular and extensible allowing new callers to be incorporated as they become available. structural variant, breakpoint, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:21194472 biotools:svmerge, OMICS_00325 https://bio.tools/svmerge SCR_004777 SciCrunch Registry SVMerge - Enhanced structural variant and breakpoint detection 2026-10-10 12:37:05 19
SVseq
 
Resource Report
Resource Website
1+ mentions
SVseq (RRID:SCR_004804) SVseq software resource Software for accurate and efficient calling of structural variations with low-coverage sequence data. Version 2 uses the BAM files of paired Illumina reads with soft-clip signature as input. It calls both deletions and insertions. structural variant, deletion, insertion, breakpoint, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Connecticut; Connecticut; USA
PMID:22537045 OMICS_00327, biotools:svseq https://bio.tools/svseq SCR_004804 SciCrunch Registry SVseq2, SVseq1 2026-10-10 12:37:02 3
NetNGlyc
 
Resource Report
Resource Website
1000+ mentions
NetNGlyc (RRID:SCR_001570) NetNGlyc analysis service resource, data analysis service, production service resource, service resource, software application, software resource Server that predicts N-Glycosylation sites in human proteins using artificial neural networks that examine the sequence context of Asn-Xaa-Ser/Thr sequons. NetNGlyc 1.0 is also available as a stand-alone software package, with the same functionality as the service above. Ready-to-ship packages exist for the most common UNIX platforms. predict, n-glycosylation site, human, protein, neural network, sequence, asn-xaa-ser/thr sequon, glycoprotein, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: CBS Prediction Servers
Free, Freely available nlx_153863, biotools:netnglyc https://bio.tools/netnglyc SCR_001570 SciCrunch Registry NetNGlyc Server 2026-10-10 12:35:55 1828
YinOYang
 
Resource Report
Resource Website
100+ mentions
YinOYang (RRID:SCR_001605) YinOYang analysis service resource, data analysis service, production service resource, service resource, software application, software resource Server that produces neural network predictions for O-beta-GlcNAc attachment sites in eukaryotic protein sequences. This server can also use NetPhos, to mark possible phosphorylated sites and hence identify Yin-Yang sites. YinOYang 1.2 is available as a stand-alone software package, with the same functionality. Ready-to-ship packages exist for the most common UNIX platforms. neural network, prediction, o-beta-glcnac attachment site, protein sequence, protein, sequence, glycosylation site, proteome, post-translational modification, protein function, glycoprotein, bio.tools uses: NetPhos
is listed by: bio.tools
is listed by: Debian
has parent organization: CBS Prediction Servers
Danish National Research Foundation PMID:11928486 Free, Freely available nlx_153865, biotools:yinoyang https://bio.tools/yinoyang SCR_001605 SciCrunch Registry 2026-10-10 12:35:55 118
Clustal Omega
 
Resource Report
Resource Website
10000+ mentions
Clustal Omega (RRID:SCR_001591) Clustal Omega, Clustalo alignment software, data processing software, image analysis software, service resource, software application, software resource Software package as multiple sequence alignment tool that uses seeded guide trees and HMM profile-profile techniques to generate alignments between three or more sequences. Accepts nucleic acid or protein sequences in multiple sequence formats NBRF/PIR, EMBL/UniProt, Pearson (FASTA), GDE, ALN/Clustal, GCG/MSF, RSF. multiple, sequence, alignment, DNA, RNA, protein, generate, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Clustal W2
is related to: Clustal W2
is related to: Clustal 2
has parent organization: European Bioinformatics Institute
has parent organization: University College Dublin; Dublin; Ireland
Science Foundation Ireland PMID:21988835
PMID:20439314
DOI:10.1038/msb.2011.75
Free, Available for download, Freely available OMICS_00972, SCR_016062, biotools:clustalo, nlx_153836 https://sources.debian.org/src/clustalo/, http://www.clustal.org/omega/, http://mobyle.pasteur.fr/cgi-bin/portal.py#forms::clustalO-multialign, https://bio.tools/clustalo, https://sources.debian.org/src/clustalo/ SCR_001591 SciCrunch Registry 2026-10-10 12:35:58 10580
asSeq
 
Resource Report
Resource Website
1+ mentions
asSeq (RRID:SCR_001625) asSeq data analysis software, data processing software, software application, software resource, source code Software that establishes a statistical framework for future developments of eQTL (expression quantitative trait locus) mapping methods using RNA-seq data (e.g., linkage-based eQTL mapping), and the joint study of multiple genetic markers and/or multiple genes. This R package has been submitted to R/bioconductor. It will be available on bioconductor soon. It is recommended to install this R package from bioconductor. You can also install this R package from the source code by yourself. Since the R package contains C code, a C complier is required for installation. With both R and appropriate c complier installed, this R package can be installed using the following command (in Mac Terminal window or Windows command window) R CMD INSTALL asSeq r, rna-seq, expression quantitative trait locus, total read count, allele-specific expression, allele-specific gene expression, gene expression quantitative trait locus, rna isoform, gene expression, genetic marker, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Bioconductor
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
PMID:21838806 Free, Available for download, Freely available OMICS_01948, nlx_153893, biotools:asseq https://bio.tools/asseq SCR_001625 SciCrunch Registry 2026-10-10 12:36:07 6
PyLOH
 
Resource Report
Resource Website
1+ mentions
PyLOH (RRID:SCR_001511) software resource Software for deconvolving tumor purity and ploidy by integrating copy number alterations and loss of heterozygosity. The model resolves the identifiability problem by integrating two types of sequencing information - somatic copy number alterations and loss of heterozygosity - within an unified probabilistic framework. standalone software, python, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24695406 Free, Available for download, Freely available OMICS_03559, biotools:pyloh https://bio.tools/pyloh SCR_001511 SciCrunch Registry 2026-10-10 12:36:01 6
MatrixDB
 
Resource Report
Resource Website
50+ mentions
MatrixDB (RRID:SCR_001727) MatrixDB data or information resource, database, production service resource, service resource Freely available database focused on interactions established by extracellular proteins and polysaccharides, taking into account the multimeric nature of the extracellular proteins (e.g. collagens, laminins and thrombospondins are multimers). MatrixDB is an active member of the International Molecular Exchange (IMEx) consortium and has adopted the PSI-MI standards for annotating and exchanging interaction data. It includes interaction data extracted from the literature by manual curation, and offers access to relevant data involving extracellular proteins provided by the IMEx partner databases through the PSICQUIC webservice, as well as data from the Human Protein Reference Database. The database reports mammalian protein-protein and protein-carbohydrate interactions involving extracellular molecules. Interactions with lipids and cations are also reported. MatrixDB is focused on mammalian interactions, but aims to integrate interaction datasets of model organisms when available. MatrixDB provides direct links to databases recapitulating mutations in genes encoding extracellular proteins, to UniGene and to the Human Protein Atlas that shows expression and localization of proteins in a large variety of normal human tissues and cells. MatrixDB allows researchers to perform customized queries and to build tissue- and disease-specific interaction networks that can be visualized and analyzed with Cytoscape or Medusa. Statistics (2013): 2283 extracellular matrix interactions including 2095 protein-protein and 169 protein-glycosaminoglycan interactions. extracellular, protein fragment, biomolecule, cation, cleavage, collagen, glycosaminoglycan, human, interaction, laminin, lipid, mammalian, matricryptin, matrikin, matrix, molecule, monomer, mulimerization, multimer, polysaccharide, protein, protein-carbohydrate interaction, protein-protein interaction, recognition, thrombospondin, interactome, extracellular protein, protein-polysaccharide interaction, extracellular interaction, molecular interaction, model organism, inorganic, small molecule-protein, small molecule, extracellular matrix protein, protein-glycosaminoglycan interaction, bio.tools, FASEB list is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: IMEx - The International Molecular Exchange Consortium
is related to: Gene Ontology
is related to: PSI-MI
is related to: HPRD - Human Protein Reference Database
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: IMEx - The International Molecular Exchange Consortium
is related to: PSICQUIC Registry
is related to: IntAct
has parent organization: Claude Bernard University Lyon 1; Lyon; France
European Union contract FP7-HEALTH-2007-223411 PMID:20852260
PMID:19147664
THIS RESOURCE IS NO LONGER IN SERVICE biotools:matrixdb, r3d100010672, nif-0000-10226 https://bio.tools/matrixdb, https://doi.org/10.17616/R3M03H http://matrixdb.ibcp.fr/ SCR_001727 SciCrunch Registry MatrixDB: Extracellular Matrix Interactions Database, Extracellular Matrix Interactions Database 2026-10-10 12:36:10 95
Biocatalogue - The Life Science Web Services Registry
 
Resource Report
Resource Website
1+ mentions
Biocatalogue - The Life Science Web Services Registry (RRID:SCR_001679) BioCatalogue data access protocol, data or information resource, database, software resource, web service Crowd-curated catalog of life sciences Web services with over 2400 service entries, thereby enabling users (people and programs) to discover and use these services easily. It provides a platform with several (standardized) interfaces and a suite of tools for registration of services by the community of users as well as empowers the community to extend and enhance the system. BioCatalogue provides a centralized biological web services market place which is accessible to the world as it is searchable and indexable to search engines. Additionally, it provides a quality of service standard for biological web services thereby enabling services to be classified and checked for availability, reliability and other quality measures. Primary goals: * Provide a single registration point for Web Service providers and a single search site for scientists and developers. * Providers, Expert curators and Users will provide oversight, monitor the catalog and provide high quality annotations for services. * BioCatalogue is a place where the community can find contacts and meet the experts and maintainers of these services. biological, web, life science, programmatic access, bioinformatics, registry, annotation, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: MetaLocGramN
is related to: myExperiment
is related to: bioDBcore
has parent organization: European Bioinformatics Institute
has parent organization: University of Manchester; Manchester; United Kingdom
European Union LHSG-CT-2004-512092;
EMBO ASTF 338.00-2009
PMID:20484378 THIS RESOURCE IS NO LONGER IN SERVICE biotools:biocatalogue, nif-0000-10167 https://bio.tools/biocatalogue SCR_001679 SciCrunch Registry Biocatalog 2026-10-10 12:36:00 7

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