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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
SOPRA
 
Resource Report
Resource Website
10+ mentions
SOPRA (RRID:SCR_005035) SOPRA software resource Software tool to exploit the mate pair/paired-end information for assembly of short reads from high throughput sequencing platforms, e.g. Illumina and SOLiD. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:20576136 Acknowledgement requested biotools:sopra, OMICS_00049 https://bio.tools/sopra SCR_005035 SciCrunch Registry SOPRA - Statistical Optimization of Paired Read Assembly, Statistical Optimization of Paired Read Assembly 2026-10-17 01:26:08 20
SSPACE
 
Resource Report
Resource Website
100+ mentions
SSPACE (RRID:SCR_005056) SSPACE software resource A stand-alone software program for scaffolding pre-assembled contigs using paired-read data. Main features are: a short runtime, multiple library input of paired-end and/or mate pair datasets and possible contig extension with unmapped sequence reads. scaffolding, contig, genome, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21149342
DOI:10.1093/bioinformatics/btq683
GNU General Public License, Registration required biotools:sspace, OMICS_00050 https://bio.tools/sspace, https://sources.debian.org/src/sspace/ SCR_005056 SciCrunch Registry 2026-10-17 01:26:03 435
Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets
 
Resource Report
Resource Website
1000+ mentions
Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets (RRID:SCR_005040) data or information resource, database, software resource Percolator post-processes the results of a shotgun proteomics database search program, re-ranking peptide-spectrum matches so that the top of the list is enriched for correct matches. Shotgun proteomics uses liquid chromatography-tandem mass spectrometry to identify proteins in complex biological samples. We describe an algorithm, called Percolator, for improving the rate of peptide identifications from a collection of tandem mass spectra. Percolator uses semi-supervised machine learning to discriminate between correct and decoy spectrum identifications, correctly assigning peptides to 17% more spectra from a tryptic dataset and up to 77% more spectra from non-tryptic digests, relative to a fully supervised approach. The yeast-01 data is available in tab delimetered format. The SEQUEST parameter file and target database for the yeast and worm data are also available. worm, yeast, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Washington; Seattle; USA
PMID:17952086 biotools:percolator, nlx_98814 https://bio.tools/percolator SCR_005040 SciCrunch Registry Percolator 2026-10-17 01:26:08 2729
MBCluster.Seq
 
Resource Report
Resource Website
1+ mentions
MBCluster.Seq (RRID:SCR_005079) MBCluster.Seq software resource Software to cluster genes based on Poisson or Negative-Binomial model for RNA-Seq or other digital gene expression (DGE) data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24191069 GNU General Public License, >/=v3 OMICS_01417, biotools:mbcluster.seq https://bio.tools/mbcluster.seq SCR_005079 SciCrunch Registry MBCluster.Seq: Model-Based Clustering for RNA-seq Data 2026-10-17 01:26:18 1
GRASS
 
Resource Report
Resource Website
50+ mentions
GRASS (RRID:SCR_005071) GRASS software resource A generic algorithm for scaffolding next-generation sequencing assemblies. next-generation sequencing, scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22492642 GNU General Public License, v3 biotools:GRASS, OMICS_00043 https://bio.tools/GRASS SCR_005071 SciCrunch Registry GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies, GeneRic ASembly Scaffolder 2026-10-17 01:26:09 89
SINA
 
Resource Report
Resource Website
100+ mentions
SINA (RRID:SCR_005067) SINA analysis service resource, data analysis service, production service resource, service resource, software resource Service to align and optionally taxonomically classify your rRNA gene sequences. The results can be combined with any other sequences aligned by SINA or taken from the SILVA databases by concatenation of FASTA files or using the ARB MERGE tool. Note: Submission is currently limited to at most 1000 sequences of at most 6000 bases each. If your requirements exceed this limitation, get Opens internal link in current windowSINA for local installation. alignment, taxonomic classification, rrna, gene sequence, fasta, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SILVA
is related to: ARB project
has parent organization: Max Planck Institute for Marine Microbiology; Bremen; Germany
PMID:22556368 Free, Available for download, Freely available OMICS_01438, biotools:sina https://bio.tools/sina, https://sources.debian.org/src/sina/, https://github.com/epruesse/SINA SCR_005067 SciCrunch Registry SINA Alignment Service, SILVA Incremental Aligner 2026-10-17 01:26:04 387
G-BLASTN
 
Resource Report
Resource Website
G-BLASTN (RRID:SCR_005062) G-BLASTN software resource A GPU-accelerated nucleotide alignment tool based on the widely used NCBI-BLAST. It can produce exactly the same results as NCBI-BLAST, and it also has very similar user commands. It also supports a pipeline mode, which can fully utilize the GPU and CPU resources when handling a batch of medium to large sized queries. parallel computation 4, blast, alignment, nucleotide, gpu, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BLAST
has parent organization: Hong Kong Baptist University; Hong Kong; China
has parent organization: SourceForge
Hong Kong Baptist University; Hong Kong; China FRG2/11-12/158;
NVIDIA
PMID:24463183 Free OMICS_02263, biotools:g-blastn http://sourceforge.net/projects/gblastn/, https://bio.tools/g-blastn SCR_005062 SciCrunch Registry 2026-10-17 01:26:04 0
VFS
 
Resource Report
Resource Website
1+ mentions
VFS (RRID:SCR_005138) VFS software resource A versatile high-throughput sequencing (HTS) tool for discovering viral integration events and reconstruct fusion transcripts at single-base resolution. It combines soft-clipping information, read-pair analysis, and targeted de novo assembly to discover and annotate viral-human fusion events. A simple yet effective empirical statistical model is used to evaluate the quality of fusion breakpoints. Minimal user defined parameters are required. ubuntu, debian, high-throughput sequencing, virus, reconstruct, fusion transcript, transcript, integration, fusion, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23314323 GNU General Public License, v3 OMICS_00224, biotools:viralfusionseq https://bio.tools/viralfusionseq SCR_005138 SciCrunch Registry ViralFusionSeq, ViralFusionSeq (VFS) 2026-10-17 01:26:06 1
PhenoMan
 
Resource Report
Resource Website
1+ mentions
PhenoMan (RRID:SCR_005249) PhenoMan software resource An interactive software program that integrates phenotypic data exploration, selection, management and quality control using a unified platform for association studies of rare and common variants. phenotype, quality control, statistical genetics, association study, python, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
has parent organization: Baylor University; Texas; USA
GNU General Public License, v3 biotools:phenoman, OMICS_00301 https://bio.tools/phenoman SCR_005249 SciCrunch Registry phenoman - Phenotypic data exploration selection management and quality control for association studies of rare and common variants 2026-10-17 01:26:08 1
FusionMap
 
Resource Report
Resource Website
50+ mentions
FusionMap (RRID:SCR_005242) FusionMap software resource An efficient fusion aligner which aligns reads spanning fusion junctions directly to the genome without prior knowledge of potential fusion regions. It detects and characterizes fusion junctions at base-pair resolution. FusionMap can be applied to detect fusion junctions in both single- and paired-end dataset from either gDNA-Seq or RNA-Seq studies. FusionMap runs under both Windows and Linux (requiring MONO) environments. Although it can run on 32 bit machine, it is recommended to run on 64-bit machine with 8GB RAM or more. If you have an ArrayStudio License, you can run the fusion detection easily through its GUI. windows, linux, c#, fusion gene, next-generation sequencing, gene, reference indexing, read filtering, fusion alignment, reporting, alignment, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21593131 Free, Non-commercial biotools:fusionmap, OMICS_00316 https://bio.tools/fusionmap SCR_005242 SciCrunch Registry 2026-10-17 01:26:15 89
rQuant
 
Resource Report
Resource Website
1+ mentions
rQuant (RRID:SCR_005150) rQuant software resource Software for quantitative detection of alternative transcripts with RNA-Seq data. The method, based on quadratic programming, estimates biases introduced by experimental settings and is thus a powerful tool to reveal and quantify novel (alternative) transcripts. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
PMID:20551130 biotools:rquant.web, OMICS_01286 https://bio.tools/rquant.web SCR_005150 SciCrunch Registry rQuant: quantitative detection of alternative transcripts with RNA-Seq data 2026-10-17 01:26:06 1
ShoRAH
 
Resource Report
Resource Website
10+ mentions
ShoRAH (RRID:SCR_005211) ShoRAH software resource A software package that allows for inference about the structure of a population from a set of short sequence reads as obtained from ultra-deep sequencing of a mixed sample. The package contains programs that support mapping of reads to a reference genome, correcting sequencing errors by locally clustering reads in small windows of the alignment, reconstructing a minimal set of global haplotypes that explain the reads, and estimating the frequencies of the inferred haplotypes. linux, mac os x, windows, next-generation sequencing, c++, python, perl, structure, population, short sequence read, haplotype, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: ETH Zurich; Zurich; Switzerland
PMID:21521499 GNU General Public License, v3 biotools:shorah, OMICS_00231 https://bio.tools/shorah SCR_005211 SciCrunch Registry Short Reads Assembly into Haplotypes, ShoRAH - Short Reads Assembly into Haplotypes 2026-10-17 01:26:12 36
V-Phaser 2
 
Resource Report
Resource Website
1+ mentions
V-Phaser 2 (RRID:SCR_005212) V-Phaser 2 software resource A software tool to call variants in genetically heterogeneous populations from ultra-deep sequence data. It combines information regarding the covariation (i.e. phasing) between observed variants to increase sensitivity and an expectation maximization algorithm that iteratively recalibrates base quality scores to increase specificity. V-Phaser can reliably detect rare variants in diverse populations that occur at frequencies of <1%. V-Phaser 2 is a complete rewrite of the original V-Phaser. It contains a new model for length polymorphisms (indels) and incorporates paired end read information in its phasing model. The data access and probability computation sections of the code have also been highly optimized, resulting in substantial improvements in running time and memory usage. variant, polymorphism, indel, virus, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Broad Institute
NIAID PMID:24088188 Free for academic use, Non-commercial, Http://www.broadinstitute.org/scientific-community/science/projects/viral-genomics/viral-genomics-software-license-v-phaser-2 biotools:v-phaser, OMICS_00232 https://bio.tools/v-phaser SCR_005212 SciCrunch Registry 2026-10-17 01:26:07 2
RNA-eXpress
 
Resource Report
Resource Website
1+ mentions
RNA-eXpress (RRID:SCR_005167) RNA-eXpress software resource Software designed as a user friendly solution to extract and annotate biologically important transcripts from next generation RNA sequencing data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Monash University; Melbourne; Australia
PMID:23396121 Acknowledgement requested, Non-Profit biotools:rna-express, OMICS_01285 https://bio.tools/rna-express SCR_005167 SciCrunch Registry 2026-10-17 01:26:14 5
SAMtools/BCFtools
 
Resource Report
Resource Website
1000+ mentions
SAMtools/BCFtools (RRID:SCR_005227) BCFtools software resource Provide various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format. snp, indel, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SAMTOOLS
DOI:10.1101/090811 biotools:bcftools, OMICS_13458 https://bio.tools/bcftools, https://sources.debian.org/src/bcftools/ SCR_005227 SciCrunch Registry 2026-10-17 01:26:07 1066
ORMAN
 
Resource Report
Resource Website
1+ mentions
ORMAN (RRID:SCR_005188) ORMAN software resource A software tool for resolving multi-mappings within an RNA-Seq SAM file. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24130305 OMICS_01284, biotools:orman https://bio.tools/orman SCR_005188 SciCrunch Registry ORMAN : Optimal Resolution of Ambiguous RNA-Seq Multi-mappings in the Presence of Novel Isoforms 2026-10-17 01:26:12 4
Knime4Bio
 
Resource Report
Resource Website
1+ mentions
Knime4Bio (RRID:SCR_005376) Knime4Bio software resource A set of custom nodes for the KNIME (The Konstanz Information Miner) graphical workbench, for analysing next-generation sequencing (NGS) data without the requirement of programming skills. node, next-generation sequencing, knime, bioinformatics, workflow, sequencing, flow, data, bam, wig, bed, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:21984761 GNU General Public License, v3 biotools:knime4bio, OMICS_01143 https://bio.tools/knime4bio SCR_005376 SciCrunch Registry Knime4Bio: custom nodes for the interpretation of Next Generation Sequencing data with KNIME 2026-10-17 01:26:16 2
PAZAR
 
Resource Report
Resource Website
10+ mentions
PAZAR (RRID:SCR_005410) PAZAR data or information resource, data repository, database, service resource, software resource, storage service resource Database that unites independently created and maintained data collections of transcription factor and regulatory sequence annotation. The flexible PAZAR schema permits the representation of diverse information derived from experiments ranging from biochemical protein-DNA binding to cellular reporter gene assays. Data collections can be made available to the public, or restricted to specific system users. The data ''boutiques'' within the shopping-mall-inspired system facilitate the analysis of genomics data and the creation of predictive models of gene regulation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. transcription factor, target gene, regulatory sequence, transcription factor profile, annotation, sequence, profile, transcription factor binding profile, chip, chip-seq, gene, cis-regulatory element, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of British Columbia; British Columbia; Canada
has parent organization: SourceForge
PMID:18971253 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00540, biotools:pazar https://bio.tools/pazar SCR_005410 SciCrunch Registry 2026-10-17 01:26:11 32
KGGSeq
 
Resource Report
Resource Website
50+ mentions
KGGSeq (RRID:SCR_005311) KGGSeq software resource A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data. The software platform, constituted of bioinformatics and statistical genetics functions, makes use of valuable biologic resources and knowledge for sequencing-based genetic mapping of variants / genes responsible for human diseases / traits. It facilitates geneticists to fish for the genetic determinants of human diseases / traits in the big sea of DNA sequences. KGGSeq has paid attention to downstream analysis of genetic mapping. The framework was implemented to filter and prioritize genetic variants from whole exome sequencing data. genomic, genetic, sequence, mutation, exome sequencing, disease, gene, variant, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Monogenic disorder, Cancer PMID:22241780 biotools:kggseq, OMICS_02260 https://bio.tools/kggseq SCR_005311 SciCrunch Registry KGGSeq: A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data 2026-10-17 01:26:15 58
Scripture
 
Resource Report
Resource Website
10+ mentions
Scripture (RRID:SCR_005269) Scripture software resource Software for transcriptome reconstruction that relies solely on RNA-Seq reads and an assembled genome to build a transcriptome ab initio. The statistical methods to estimate read coverage significance are also applicable to other sequencing data. Scripture also has modules for ChIP-Seq peak calling. transcriptome, rna-seq read, genome sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Alt Event Finder
has parent organization: Broad Institute
PMID:20436462 biotools:scripture, OMICS_01265 https://bio.tools/scripture SCR_005269 SciCrunch Registry 2026-10-17 01:26:14 11

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