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https://massspec.vai.org/

Core is committed to developing scientific partnerships with research labs to develop and deploy LC/MS and GC/MS methods specifically tailored to meet the needs of every project. Provides suite of technologies, experimental design support and staff expertise to deliver metabolomics, lipidomics, and proteomics capabilities to VARI scientists and collaborators. Analytical capabilities are combined with custom informatics and statistics solutions.Specific capabilities include: Metabolomics and Lipidomics liquid chromatography mass spectrometry (LC/MS) systems (Thermo Orbitrap ID-X, Thermo Orbitrap Exploris 240, and Agilent 6470 QQQ) and gas chromatography (GC)/MS systems (Agilent 5977b (2), Thermo 7610 ISQ) dedicated to small molecule analysis;Proteomics nano LC/MS systems (Orbitrap Eclipse and Orbitrap Exploris 480) for protein analysis; Bioinformatics for developing and maintaining informatics pipelines for mass spectrometry data analysis and visualization.Major equipment in the facility includes Thermo Scientific Orbitrap ID-X LC/MS,Thermo Scientific Orbitrap Exploris 240 LC/MS,Thermo Scientific Orbitrap Eclipse nanoLC/MS,Thermo Scientific Orbitrap Exploris 4800 LC/MS,Agilent 6470 Triple Quadrupole LC/MS ,Agilent Infinity 1290II UPLC,Agilent 5977B GC/MS,Thermo Scientific ISQ7610 EI/CI enabled GC/M.

Proper citation: Van Andel Institute Mass Spectrometry Core Facility (RRID:SCR_024903) Copy   

•   Source: SciCrunch Registry

https://stemcell.ucla.edu/microscopy-core

Microscopy Core is collaboration of Broad Stem Cell Research Center and Department of Molecular, Cell and Developmental Biology at UCLA. Provides high resolution technologies for imaging and analyzing molecular and structural organization of cells and tissue as well as bioengineered materials. Services include confocal, wide field fluorescence and live cell imaging, as well as image analysis software.

Proper citation: University of California Los Angeles Broad Stem Cell Research Center Microscopy Core Facility (RRID:SCR_024914) Copy   

•   Source: SciCrunch Registry

https://geomicrobiologylabs.stanford.edu/

Geomicrobiology analytical facilities consist of four different labs in the Green Earth Sciences Building. Main areas of study are: molecular, bio(geo)chemical, and ecological aspects of microbial cycling of nitrogen, carbon, and metals in environment diversity, distribution, and activity of microorganisms driving greenhouse gas cycling in ocean and beyond molecular biomarkers in modern organisms to refine our interpretations of microbial fossil record.

Proper citation: Stanford Geomicrobiology Shared Laboratories Core Facility (RRID:SCR_025000) Copy   

•   Source: SciCrunch Registry

https://biotech.unl.edu/cryoem

Core facility is dedicated to structural characterization of biological samples and microcrystals using cryo-electron microscopy. CryoEM workflows including, single-particle CryoEM, Cryo-electron tomography , and Micro crystal electron diffraction. Instrumentation includes TFS 200kV Glacios CryoTEM, equipped with zero-loss Selectris Energy Filter, Flacon 4i Direct Electron Detector, and Ceta-D camera, Pelco Easy Glow Discharger, TFS Vitrobot Mark IV, and Leica EM GP2. We also present all the capacities for storing and shipping samples. Facility has Data storage Server and Live processing workstation for our users� convenience, including data processing suites RELION and CryoSPARC available at our campus supercomputer Swan cluster at the Holland Computer Center.

Proper citation: University of Nebraska Lincoln CryoEM Core Facility (RRID:SCR_025012) Copy   

•   Source: SciCrunch Registry

https://sc.edu/study/colleges_schools/medicine/research/research_facilities/instrumentation_resource_facility/index.php

IRF houses biotechnological equipment that provide investigation ranging from single cell and molecular level analysis to whole animal imaging. Additionally, the IRF maintains a full range of ancillary equipment available for sample preparation, image enhancement, and data analysis.

Proper citation: University of South Carolina Instrumentation Resource Core Facility (RRID:SCR_024955) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/pgsc/

Provided services include molecular profiling of DNA and RNA on different platforms, Sanger sequencing, full service Next Generation Sequencing with different applications and bioinformatics, fragment analysis including human cell line authentication., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of Pennsylvania Penn Genomics and Sequencing Core Facility (RRID:SCR_024999) Copy   

•   Source: SciCrunch Registry

https://cellsort.caltech.edu

Facility offers cell analyzers and cell sorters as well as expertise in large range of traditional immunophenotyping and small particle, geo-physical applications.

Proper citation: California Institute of Technology Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_025087) Copy   

•   Source: SciCrunch Registry

https://researchservices.pitt.edu/facilities/mass-spectrometry-lab

Core provides mass spectrometry instruments including Bruker Daltonics UltrafleXtreme MALDI TOF-TOF, Shimadzu Instrument LCMS-2020,Shimadzu Instrument QP2010S GCMS,Thermo Fisher Oribtrap Exploris 240,Thermo Scientific Q-Exactive Oribtrap for determining masses of particles, and elemental composition of sample or molecule.

Proper citation: University of Pittsburgh Dietrich School Mass Spectrometry Core Facility (RRID:SCR_025123) Copy   

•   Source: SciCrunch Registry

https://researchservices.pitt.edu/facilities/nmr-spectroscopy-lab

Facility specializes in training users in both solution phase and solid state NMR across all active nuclei and multiple NMR experients

Proper citation: University of Pittsburgh Dietrich School NMR Core Facility (RRID:SCR_025126) Copy   

•   Source: SciCrunch Registry

https://www.mines.edu/shared-facilities/project_category/water-quality-analysis/

Core facility houses the capability to test water using multiple instruments and techniques including : Ion Chromatography, which is an analytical technique for determining the concentration of anions in aqueous solutions such as fluoride, chloride, nitrate, phosphate and sulfate; Carbon and nitrogen analysis, which incorporates measurements of total carbon, total inorganic carbon and total organic carbon together with total nitrogen; and other parameters such as pH, alkalinity, turbidity, conductivity (and others) using instrumentation and kits.

Proper citation: Colorado School of Mines Shared Instrumentation Facility Water Quality Analysis Core Facility (RRID:SCR_025080) Copy   

•   Source: SciCrunch Registry

https://www.immunology.pitt.edu/flow-cytometry-overview

Core provides flow cytometry and cell sorting services. Staff offers help with instrument setup, data analysis, and consultation for experiment design. Training is available to run analytical cytometers.Houses FACSAria cell sorters, Cytek Aurora Cell Sorter, LSR Fortessas , LSR IIs, ImageStreamx Mark II and 4 full spectral cytometers., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of Pittsburgh Unified Flow Cytometry Core Facility (RRID:SCR_025102) Copy   

•   Source: SciCrunch Registry

https://cancer.dartmouth.edu/scientists-researchers/microscopy-resource

Facility provides imaging instrumentation and analysis software along with training and expertise.Instrumentation and technologies available to users include Zeiss LSM800 AIRYSCAN confocal microscope integrated with Zen software; PerkinElmer / Akoya Vectra 3.0 Automated Quantitative Pathology Imaging System;Agilent/BioTek Cytation 5 with BioSpa8 live-cell microscopy system for fluorescence and phase contrast microscopy; Olympus IX-83 ZDC2 microscope equipped with PRIMO UV light-based bioengineering device for micropatterning and microfabrication; Olympus IX73 Inverted Fluorescence Microscope.Image analysis software hosted on appropriately powered workstations with cloud connectivity for high capacity storage: HALO3, Inform, Volocity, AutoDeblur, Image-J / Fiji.Transmission and scanning electron microscopy including FEI Talos F200i (200kV TEM and STEM electron microscope (TEM), equipped for micro-analysis, and cryo-EM;FEI Helios CX5 dual beam FIB-SEM system with X-ray microanalysis detectors; instruments for specimen preparation for transmission and scanning electron microscopy including ultramicrotomes Leica Ultracut UC6 and UC7, critical point dryer Samdri-970, Leica ACE 600 coater and ThermoFisher Vitrobot.

Proper citation: Geisel School of Medicine at Dartmouth DCC Microscopy Shared Resource Core Facility (RRID:SCR_025076) Copy   

•   Source: SciCrunch Registry

http://www.colorado.edu/mri

Magnetic resonance imaging research facility located at University of Colorado Boulder.

Proper citation: University of Colorado Boulder Intermountain Neuroimaging Consortium Core Facility (RRID:SCR_025079) Copy   

•   Source: SciCrunch Registry

https://www.luc.edu/stritch/cancerbiology/corefacilities/

Core Facility with conventional, full-spectrum, cell sorting and flow cytometry services. Training provided by core personnel.

Proper citation: Loyola University School of Medicine Flow Cytometry Core Facility (RRID:SCR_025109) Copy   

•   Source: SciCrunch Registry

https://scic.pme.uchicago.edu

Core is self service facility that provides access to specialized instrumentation for phenotyping and genotyping of immune cells. Offers single cell next generation sequencing and quality control technologies. All instruments are located in the laboratories of four different CIIC investigators (KCBD 10220E and 10220C), and are available for use by the larger UChicago community.

Proper citation: University of Chicago Single Cell Immunophenotyping Core Facility (RRID:SCR_025140) Copy   

•   Source: SciCrunch Registry

https://mageewomens.org/for-researchers/core-facilities/genome-editing-transgenic-and-virus-getv-core

Core provides technical expertise, advice, and training and is comprised of three functional sections: Molecular cloning (plasmid, virus, CRISPR/Cas9); Viral vectors (lentivirus, adenovirus, adeno-associated virus); Animal services (transgenic, knockout, cryopreservation, re-derivation, and more). Services offered include Assistance for generating recombinant plasmids; Design and implementation of CRISPR/Cas9 technology for in vivo and in vitro work; Mouse and rat transgenesis,including transgenic and knockout/knockdown techniques using pronuclear injection, ES cell injection/chimera, and CRISPR/Cas9-mediated genome editing; Production of lentivirus, adenovirus, and adeno-associated virus vectors; Additional animal testing and procedures: teratoma and chimera testing to validate putative pluripotent stem cell lines, cryopreserve or re-derive of valuable transgenic lines (sperm or embryos).

Proper citation: University of Pittsburgh Genome Editing, Transgenic and Virus Core Facility (RRID:SCR_025151) Copy   

•   Source: SciCrunch Registry

https://vmi.pitt.edu/research/cores/ultrasonography/

Core provides expertise and high frequency ultrasound instrumentation suitable for image acquisition and analysis applicable to your research studies. Provides Fuji/Visualsonics Vevo 3100 ultrasound imaging machine to perform ultrasounds on small animals. The scanner has high temporal and spatial resolution; current imaging probes utilize frequencies from 13-55 MHz.

Proper citation: University of Pittsburgh Small Animal Ultrasonography Core Facility (RRID:SCR_025152) Copy   

•   Source: SciCrunch Registry

http://www.GCCRD.CA

Advanced imaging core for multi channel fluorescence imaging,3D imaging, super resolution imaging, scanning, image analysis in cancer research. Technical services are forcused on fluorescent in situ hybridization, immunohistochemistry, and microdissection of biological material.

Proper citation: University of Manitoba Genomic Centre for Cancer Research and Diagnosis Core Facility (RRID:SCR_025133) Copy   

•   Source: SciCrunch Registry

https://hillmanresearch.upmc.edu/research/facilities/cancer-proteomics/luminex-core-laboratory/

Facility utilizes LabMA system developed by Luminex Co., for protein analysis that permits simultaneous quantitative analysis of up to 100 different proteins, peptides, or RNA molecules in single microtiter well. Commercially available assays from Millipore, R&D Systems, Bio-Rad or Thermofisher are also used for analysis.

Proper citation: University of Pittsburgh Luminex Core Facility (RRID:SCR_025134) Copy   

•   Source: SciCrunch Registry

https://www.pediatrics.pitt.edu/research/cores-and-research-support/metabolic-core

Core provides Instrument Services for analysis of 1) endogenous metabolic pathway intermediates or biomarkers from biological fluids, cell cultures, and tissues using Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS), 2) energy metabolism (cell bioenergetics) in living cells using a Seahorse Analyzer, and 3) biomarkers/metabolites to quantitate pathway intermediates using HPLC with 3 detector options (ECD, UV-VIS, FLR).

Proper citation: University of Pittsburgh School of Medicine Metabolic Core Facility (RRID:SCR_025224) Copy   

•   Source: SciCrunch Registry