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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://indianactsi.org/servicecores/core/60/
Core provides following services: Brachial artery flow-mediated dilation; Brachial artery nitroglycerin-mediated dilation; Carotid artery intima media thickness.
Proper citation: Indiana University School of Medicine Human Vascular Imaging Core Facility (RRID:SCR_025558) Copy
https://vet.purdue.edu/ctr/histology/
Full service histology laboratory that provides general histology, immunohistochemistry, frozen sectioning, decalcified and undecalcified bone histology, and slide digitization services. Board certified veterinary pathologists are also available for consultation.
Proper citation: Purdue University Histology Research Laboratory Core Facility (RRID:SCR_025559) Copy
https://biotech.unl.edu/single-cell/
Facility provides access to Chromium iX platform from 10X Genomics. This allows user to barcode single cells or nuclei and process them for single cell RNA-seq, single nucleus ATAC-seq or single nucleus Multiome ATC + Gene Expression protocols.
Proper citation: University of Nebraska Lincoln Single Cell Genomics Core Facility (RRID:SCR_025609) Copy
https://medicine.iu.edu/internal-medicine/research/centers/biological-microscopy
Provides researchers with access to laser-scanning confocal, 2-photon and epi-fluorescence microscopes. Personnel train individual researchers to use all imaging systems and provide expert help in design, conduct and analysis of imaging studies. As necessary, center personnel can also be hired to conduct microscopy studies for laboratories lacking necessary expertise.
Proper citation: Indiana University School of Medicine Center for Biological Microscopy Core Facility (RRID:SCR_025568) Copy
https://www.organoids.pitt.edu/
Core has large collection of unique patient-derived organoids (PDOs). Staff provides high-quality training in organoid development and culture, consultation services to assist with experimental design, execution, and data analysis.
Proper citation: University of Pittsburgh Organoid Research Core Facility (RRID:SCR_025698) Copy
http://noncodingrna.org/bioinformatics-unit/
BIDMC Bioinformatics Core is Unit of the Precision RNA Medicine Core and provides support for management, integration and contextual analysis of biological high-throughput data, training on tools, databases and best practice.
Proper citation: Harvard Medical School Beth Israel Deaconess Medical Center Bioinformatics Core Facility (RRID:SCR_025859) Copy
https://www.childrenshospital.org/research/cores/molecular-genetics-core/contact-us
Provides genomic technology services and expertise. Services offered include Nanopore PromethION sequencing, Electronic optical mapping on Nabsys, Optical Genome mapping on Bionano Saphyr, NGS (Illumina-based), Sanger Sequencing, Single cell analysis/RNAseq, Transcriptomic spatial profiling, Gene expression analysis , Droplet Digital PCR & qPCR, Microsatellite/fragment analysis, SNP genotyping , Chromosomal microarray analysis, Sample prep and QC, Project consultation, Bioinformatics support.
Proper citation: Boston Children's Hospital Molecular Genetics Core Facility (RRID:SCR_025866) Copy
https://cryoem.hms.harvard.edu
Joint effort by Harvard Medical School, Dana-Farber Cancer Institute, Boston Childrens Hospital, and Massachusetts General Hospital to provide cryo-EM instrumentation and expertise for Harvard structural biology community. Facility offers consultation and training by staff in specimen preparation, microscope operation, image acquisition, and data analysis.
Proper citation: Harvard Medical School Harvard Cryo-Electron Microscopy Center for Structural Biology Core Facility (RRID:SCR_025841) Copy
Service facility offering generation of novel transgenic mouse models using CRISPR/Cas9 gene editing technology. Standard service includes consultation, design, testing, prep, mouse embryo microinjection, and genotyping.
Proper citation: University of Washington Mouse CRISPR Core Facility (RRID:SCR_025836) Copy
https://www.brandeis.edu/science/resources/light-microscopy/index.html
Facility houses 13 high-end light microscopes including point scanning and spinning disk confocals, Airyscan, 3D-STED super resolution, widefield and TIRF systems. Core offers training, consultation and access to powerful analysis computers with licensed softwares.
Proper citation: Brandeis University Light Microscopy Core Facility (RRID:SCR_025892) Copy
Mass spectrometry based proteomics.
Proper citation: University of Kansas Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_025893) Copy
https://www.rockefeller.edu/hpc/
Provide Rockefeller University researchers and collaborators with infrastructure necessary for computationally intensive workloads, as well as training and support for using these resources.
Proper citation: Rockefeller University High Performance Computing Core Facility (RRID:SCR_025889) Copy
https://douglas.research.mcgill.ca/molecular-and-cellular-microscopy-platform-mcmp/
Provides access to various microscopes and services, support and training for fluorescence microscopy experiments and image analysis. Facility offers imaging tasks from basic neuron reconstruction to high-speed, deep-tissue optogenetic experiments in brain slices or live animals.
Proper citation: Douglas Institute Molecular and Cellular Microscopy Platform Core Facility (RRID:SCR_026037) Copy
http://www.douglasbrainbank.ca
Based at the Douglas Research Centre, the Douglas Brain Bank (DBB) houses a large collection of brains from people with diverse psychiatric disorders, including schizophrenia, major depression, bipolar disorder and substance use disorders, as well as brains from individuals with various neurological and developmental disorders such as amyotrophic lateral sclerosis (ALS), Alzheimers disease and autism spectrum disorder (ASD). In addition, the DBCBB manages a large relational database containing demographic, clinical and developmental histories from donors.
Proper citation: Douglas Mental Health University Institute Douglas Brain Bank Core Facility (RRID:SCR_025991) Copy
https://versiti.org/versiti-blood-research-institute/core-facilities-services/bioinformatics
Core offers bioinformatics consultation, training, and data analysis to help investigators analyze and understand large-scale biological datasets required from different platforms, including next generation sequencing, array-based technologies and mass spectrometry. Provides development and operation of standard and advanced data processing pipelines, covering tasks such as bulk next-generation sequencing analysis (e.g., RNA-Seq, DNA-Seq, methyl-Seq, and ChIP-Seq), single-cell analysis, transcriptome and genome annotation, variant detection and interpretation and metagenomics. Our team members have extensive experience in bioinformatics, biostatistics, genomics, genetics, transcriptomics and translational informatics in human, animal and microbial systems. Our expertise includes big data analysis, statistical analysis, machine learning, neuro network, software development and high-performance computing. Our approach prioritizes scientific collaboration, going beyond mere service provision to leverage our skills and knowledge for the success of your projects. Offers support for grant applications, including key personnel involvement, support letters, and analytical method write-ups.
Proper citation: Versiti Blood Research Institute Bioinformatics Core Facility (RRID:SCR_025993) Copy
https://bioinspired.syr.edu/MRC/
Provides services involved in fundamental studies of biochemical and physical processes controlling cell functions to development of new technologies for biomedical applications.
Proper citation: Syracuse University BioInspired Materials Research Core Facility (RRID:SCR_025987) Copy
http://www.lsuhs.edu/fwcc-biorepository
Provides IRB-approved research projects or clinical trials with human tissue samples or hematological samples. Supports translational research by functioning as primary fresh-frozen tissue acquisition and processing facility for human solid tissue and hematopoietic specimens.FWCC Biorepository works in collaboration with medical and surgical teams at Ochsner LSU Health Shreveport, the Department of Pathology to procure remnant tissue for research purposes, and investigators in need of biospecimens for their research. Provides customized services and equipment to assist investigators in the procurement, analyses, and clinicopathologic correlation of human tissue specimens.
Proper citation: Louisiana State University Health Sciences Center Shreveport Feist Weiller Cancer Center Biorepository Core Facility (RRID:SCR_026020) Copy
https://dac.institutducerveau-icm.org/
Core provides structural support and expertise in processing, integrating, analyzing and managing neuroscience data.
Proper citation: Paris Brain Institute Data Analysis Core Facility (RRID:SCR_026138) Copy
https://ecosystemslab.sites.stanford.edu/
Ecosystems Laboratory provides bench space, laboratory supplies, chemicals, sample preparation equipment, and sample storage space to enhance and facilitate research within Stanford University community.
Proper citation: Stanford Ecosystems Shared Laboratory Core Facility (RRID:SCR_026190) Copy
https://research.yale.edu/cores/keck-mass-spectrometry-proteomics-resource
Core provides proteomics and small molecule mass spectrometry services to separate, characterize, profile, and quantify analytes from complex biological samples.
Proper citation: Yale Keck Mass Spectrometry and Proteomics Resource Core Facility (RRID:SCR_026192) Copy
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