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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
YLoc
 
Resource Report
Resource Website
10+ mentions
YLoc (RRID:SCR_002464) YLoc analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, web service An interpretable web server for predicting subcellular localization. In addition to the predicted location, YLoc gives a reasoning why this prediction was made and which biological properties of the protein sequence lead to this prediction. Moreover, a confidence estimate helps users to rate predictions as trustworthy. YLoc+ is able to predict the location of multiple-targeted proteins with high accuracy. The YLoc webserver is also accessible via SOAP. subcellular localization, protein is listed by: OMICtools
has parent organization: University of Tubingen; Tubingen; Germany
PMID:20507917
PMID:20299325
Acknowledgement requested OMICS_01638 SCR_002464 Yloc - Interpretable Subcellular Localization Prediction 2026-09-12 01:00:08 36
ngLOC
 
Resource Report
Resource Website
10+ mentions
ngLOC (RRID:SCR_003150) ngLOC analysis service resource, data analysis service, production service resource, service resource, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 5, 2023.An n-gram-based Bayesian classifier that predicts subcellular localization of proteins both in prokaryotes and eukaryotes. The downloadable version of this software with source code is freely available for academic use under the GNU General Public License. subcellular localization, protein, eukaryote, prokaryote, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22780965
PMID:17472741
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01629, biotools:ngloc https://bio.tools/ngloc SCR_003150 ngLOC - A Bayesian method for predicting protein subcellular localization 2026-09-12 01:00:09 22
ImaGene
 
Resource Report
Resource Website
100+ mentions
ImaGene (RRID:SCR_002178) data analysis software, data processing software, software application, software resource Software tool as convolutional neural network to quantify natural selection from genomic data.Supervised machine learning algorithm to predict natural selection and estimate selection coefficients from population genomic data. Can be used to estimate any parameter of interest from evolutionary population genetics model., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. microarray analysis, machine vision, convolutional neural network, quantify natural selection, genomic data, population genomic data, evolutionary population, genetics model, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Imperial College London ;
Politecnico di Milano
PMID:31757205 THIS RESOURCE IS NO LONGER IN SERVICE biotools:ImaGene, OMICS_00841 https://github.com/mfumagalli/ImaGene, https://bio.tools/ImaGene http://www.biodiscovery.com/software/imagene/ SCR_002178 2026-09-12 01:00:07 405
SNPMeta
 
Resource Report
Resource Website
1+ mentions
SNPMeta (RRID:SCR_002005) SNPMeta analysis service resource, data analysis service, production service resource, service resource, software resource A Python and BioPython-based tool to generate metadata for single nucleotide polymorphisms (SNPs) for easy filtering, or submission to SNP databases. Information reported includes gene name, whether the SNP is coding or noncoding, and whether the SNP is synonymous or nonsynonymous. SNPMeta outputs in either a dbSNP submission report format, or a tab-delimited format. There is a also Web-based version available that only annotates with default settings, and only annotates a maximum of 20 SNPs at one time. The script may be downloaded for full functionality. single nucleotide polymorphism, coding, noncoding, , synonymous, nonsynonymous, python, biopython, metadata, annotation is listed by: OMICtools
has parent organization: University of Minnesota Twin Cities; Minnesota; USA
PMID:24237904 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01923 SCR_002005 2026-09-12 01:00:07 1
QualitySNPng
 
Resource Report
Resource Website
1+ mentions
QualitySNPng (RRID:SCR_002479) data processing software, data visualization software, software application, software resource, standalone software Software for the detection and visualization of single nucleotide polymorphisms (SNPs) from next generation sequencing data that uses a haplotype-based strategy. single nucleotide polymorphism, haplotype strategy, next generation sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23632165 Free, Available for download, Freely available biotools:qualitysnpng, OMICS_00070 https://bio.tools/qualitysnpng SCR_002479 2026-09-12 01:00:08 7
PBSIM
 
Resource Report
Resource Website
10+ mentions
PBSIM (RRID:SCR_002512) simulation software, software application, software resource Software that simulates PacBio reads by using either a model-based or sampling-based simulation. pacbio simulation, model-based simulation, sampling-based simulation is listed by: OMICtools
is listed by: Debian
PMID:23129296
DOI:10.1093/bioinformatics/bts649
Free, Available for download, Freely available OMICS_00253 https://sources.debian.org/src/pbsim/ SCR_002512 PacBio reads simulator 2026-09-12 01:00:08 11
MAQC
 
Resource Report
Resource Website
10+ mentions
MAQC (RRID:SCR_002351) MAQC data or information resource, knowledge environment, narrative resource, standard specification Project to improve the microarray and next-generation sequencing technologies and foster their proper applications in discovery, development and review of FDA regulated products by developing standards and quality measures. Microarrays and next-generation sequencing represent core technologies in pharmacogenomics and toxicogenomics; however, before these technologies can successfully and reliably be used in clinical practice and regulatory decision-making, standards and quality measures need to be developed. Everyone is invited to participate in the MAQC project. microarray, next-generation sequencing, pharmacogenomics, toxicogenomics, quality control is listed by: OMICtools
has parent organization: National Center for Toxicological Research
OMICS_01784 SCR_002351 MicroArray Quality Control 2026-09-12 01:00:08 21
RAVEN
 
Resource Report
Resource Website
100+ mentions
RAVEN (RRID:SCR_001937) RAVEN analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Tool to search for putative regulatory genetic variation in your favorite gene. Single nucleotide polymorphisms (SNPs) (from dbSNP and user defined) are analyzed for overlap with potential transcription factor binding sites (TFBS) and phylogenetic footprinting using UCSC phastCons scores from multiple alignments of 8 vertebrate genomes., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. transcription factor binding site, phylogenetic footprint, regulatory sequence variation, genetic variation, in silico, regulatory sequence, FASEB list uses: Embassy-domsearch
is listed by: OMICtools
has parent organization: University of British Columbia; British Columbia; Canada
PMID:18208319 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01932 SCR_001937 Regulatory analysis of Variation in Enhancers, RAVEN - Regulatory analysis of Variation in ENhancers 2026-09-12 01:00:07 127
qrqc
 
Resource Report
Resource Website
1+ mentions
qrqc (RRID:SCR_006867) qrqc data analysis software, data processing software, sequence analysis software, software application, software resource Software R package to quickly scan reads and gather statistics on base and quality frequencies, read length, k-mers by position, and frequent sequences. Produces graphical output of statistics for use in quality control pipelines, and an optional HTML quality report. S4 SequenceSummary objects allow specific tests and functionality to be written around the data collected. Quickly scan reads, read length, k-mers, position, frequent sequences, quality control pipeline, HTML quality report, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:qrqc, OMICS_01071 https://github.com/vsbuffalo/qrqc, https://bio.tools/qrqc SCR_006867 quick read quality control, Quick Read Quality Control 2026-09-12 01:00:12 2
SNPeffect
 
Resource Report
Resource Website
50+ mentions
SNPeffect (RRID:SCR_005091) SNPeffect analysis service resource, data analysis service, data or information resource, database, production service resource, service resource A database for phenotyping human single nucleotide polymorphisms (SNPs)that primarily focuses on the molecular characterization and annotation of disease and polymorphism variants in the human proteome. They provide a detailed variant analysis using their tools such as: * TANGO to predict aggregation prone regions * WALTZ to predict amylogenic regions * LIMBO to predict hsp70 chaperone binding sites * FoldX to analyse the effect on structure stability Further, SNPeffect holds per-variant annotations on functional sites, structural features and post-translational modification. The meta-analysis tool enables scientists to carry out a large scale mining of SNPeffect data and visualize the results in a graph. It is now possible to submit custom single protein variants for a detailed phenotypic analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. single nucleotide polymorphism, phenotyping, mutation, protein-coding variant, molecule, structure, phenotype, non-synonymous coding snp, allelic variation, gene, protein stability, functional site, protein phosphorylation, glycosylation, subcellular localization, protein turnover, protein aggregation, amyloidosis, chaperone interaction, protein variant, FASEB list is listed by: OMICtools
has parent organization: Catholic University of Leuven; Flemish Brabant; Belgium
PMID:22075996
PMID:18086700
PMID:16809394
PMID:15608254
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00187, nif-0000-03480 http://snpeffect.switchlab.org/ SCR_005091 SNPeffect 4 Phenotyping Human Mutations 2026-09-12 01:00:10 62
hmChIP
 
Resource Report
Resource Website
1+ mentions
hmChIP (RRID:SCR_005407) hmChIP analysis service resource, data analysis service, data or information resource, database, production service resource, service resource A database of genome-wide chromatin immunoprecipitation (ChIP) data in human and mouse. Currently, the database contains >2000 samples from >500 ChIP-seq and ChIP-chip experiments, representing a total of >170 proteins and >10,000,000 protein-DNA interactions (March 2014). A web server provides an interface for database query. Protein-DNA binding intensities can be retrieved from individual samples for user-provided genomic regions. The retrieved intensities can be used to cluster samples and genomic regions to facilitate exploration of combinatorial patterns, cell type dependencies, and cross-sample variability of protein-DNA interactions. chromatin immunoprecipitation, chip-seq, chip-chip, protein, protein-dna interaction, binding intensity is listed by: OMICtools
has parent organization: Johns Hopkins Bloomberg School of Public Health; Maryland; USA
PMID:21450710 The community can contribute to this resource OMICS_00536 SCR_005407 2026-09-12 01:00:11 5
ChEA
 
Resource Report
Resource Website
100+ mentions
ChEA (RRID:SCR_005403) ChEA analysis service resource, data analysis service, data or information resource, database, production service resource, service resource, software application, software resource Data analysis service for gene-list enrichment analysis against a manual database. It allows users to input lists of mammalian gene symbols for which the program computes over-representation of transcription factor targets from the ChIP-X database. The database integrates interaction data from ChIP-chip, ChIP-seq, ChIP-PET and DamID studies and contains 189,933 interactions, manually extracted from 87 publications, describing the binding of 92 transcription factors to 31,932 target genes. chip, transcription factor, interaction, mrna expression, gene, target gene, command-line, chip-chip, chip-seq is listed by: OMICtools
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
PMID:20709693 OMICS_00526 SCR_005403 ChIP Enrichment Analysis 2026-09-12 01:00:11 280
Hadoop-BAM
 
Resource Report
Resource Website
1+ mentions
Hadoop-BAM (RRID:SCR_005516) Hadoop-BAM software library, software resource, software toolkit A Java library for the manipulation of files in common bioinformatics formats using the Hadoop MapReduce framework with the Picard SAM JDK, and command line tools similar to SAMtools. The file formats currently supported are BAM, SAM, FASTQ, FASTA, QSEQ, BCF, and VCF. mapreduce/hadoop, java, next generation sequencing data, cloud is listed by: OMICtools
has parent organization: SourceForge
PMID:22302568 MIT License OMICS_01051 SCR_005516 2026-09-12 01:00:11 7
SEECER
 
Resource Report
Resource Website
10+ mentions
SEECER (RRID:SCR_005274) SEECER algorithm resource, data analysis software, data processing software, sequence analysis software, software application, software resource Algorithm for sequencing error correction of RNA-seq data sets. SEECER removes mismatch and indel errors from the raw reads and improves downstream analysis of the data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
PMID:23558750 Free, Available for download OMICS_01236, biotools:seecer https://bio.tools/seecer SCR_005274 SEECER - SEquencing Error CorrEction for Rna reads 2026-09-12 01:00:11 12
HTSeq
 
Resource Report
Resource Website
5000+ mentions
HTSeq (RRID:SCR_005514) HTSeq authoring tool, data processing software, software application, software resource, standalone software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software Python package that provides infrastructure to process data from high-throughput sequencing assays. While the main purpose of HTSeq is to allow you to write your own analysis scripts, customized to your needs, there are also a couple of stand-alone scripts for common tasks that can be used without any Python knowledge. python, high-throughput sequencing assay, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: European Molecular Biology Laboratory
DOI:10.1093/bioinformatics/btu638 THIS RESOURCE IS NO LONGER IN SERVICE biotools:htseq, OMICS_01053 https://bio.tools/htseq http://www-huber.embl.de/users/anders/HTSeq/, https://sources.debian.org/src/python3-htseq/ SCR_005514 HTSeq: Analysing high-throughput sequencing data with Python 2026-09-12 01:00:11 8618
GeneTalk
 
Resource Report
Resource Website
10+ mentions
GeneTalk (RRID:SCR_005231) GeneTalk blog, community building portal, data or information resource, data repository, database, narrative resource, portal, service resource, storage service resource A web-based tool, knowledgebase and community for analysis and interpretation of human variant files. VCFs (Variant Call Formats) are preprocessed and annotated, you can filter them, access all databases and provide your expertise to the community by creating annotations. sequence variant, annotation, exome sequencing, genetic variant, gene, data sharing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22826540 The community can contribute to this resource, Free, (during beta period) OMICS_00270, biotools:genetalk https://bio.tools/genetalk SCR_005231 GeneTalk - The Professional Network and Online Tool for Geneticists 2026-09-12 01:00:10 31
MUSCLE
 
Resource Report
Resource Website
10000+ mentions
MUSCLE (RRID:SCR_011812) MUSCLE alignment software, analysis service resource, data analysis service, data analysis software, data processing software, image analysis software, production service resource, service resource, software application, software resource Multiple sequence alignment method with reduced time and space complexity.Multiple sequence alignment with high accuracy and high throughput. Data analysis service for multiple sequence comparison by log- expectation. bio.tools is used by: TranslatorX
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: PREFAB
has parent organization: European Bioinformatics Institute
PMID:15034147
PMID:15318951
DOI:10.1093/nar/gkh340
biotools:muscle, OMICS_00982 https://bio.tools/muscle, http://www.drive5.com/muscle/, https://www.drive5.com/muscle/manual/, https://www.drive5, http://bioconductor.org/packages/release/bioc/html/muscle.html.com/muscle/manual/install.html, https://sources.debian.org/src/muscle/ SCR_011812 MUltiple Sequence Comparison by Log- Expectation 2026-09-12 01:00:15 17169
CLC Genomics Workbench
 
Resource Report
Resource Website
100+ mentions
CLC Genomics Workbench (RRID:SCR_011853) data analysis software, data processing software, data visualization software, software application, software resource Commercially available software for visualization and analysis of next generation sequencing data. Used for viewing, exploring, and sharing of NGS analysis results. Complete toolkit for genomics, transcriptomics, epigenomics, and metagenomics in one program. ngs, next, generation, sequencing, gene, rna, visualisation, analysis is listed by: OMICtools
is listed by: SoftCite
works with: CLC Genomics Server
Restricted SCR_016245, OMICS_01124 SCR_011853 2026-09-12 01:00:15 187
Gwyddion
 
Resource Report
Resource Website
1000+ mentions
Gwyddion (RRID:SCR_015583) data analysis software, data processing software, software application, software resource Modular program for SPM (scanning probe microscopy) data visualization and analysis. Primarily it is intended for the analysis of height fields obtained by scanning probe microscopy techniques (AFM, MFM, STM, SNOM/NSOM) and it supports a lot of SPM data formats. However, it can be used for general height field and (greyscale) image processing, for instance for the analysis of profilometry data or thickness maps from imaging spectrophotometry. spm data analysis, spm data visualization, height field analysis is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
Czech Metrology Institute Department of Nanometrology DOI:10.2478/s11534-011-0096-2 Open source OMICS_07548 https://sources.debian.org/src/gwyddion/ SCR_015583 2026-09-12 01:00:17 1661
DoG picker
 
Resource Report
Resource Website
10+ mentions
DoG picker (RRID:SCR_016655) DoG picker data processing software, image processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 18,2023. Software tool for general particle picking in the single-particle processing of unknown macromolecules. Reference free particle picker with ability to sort particles based on size or it can be used to bootstrap the creation of templates or training datasets for other particle pickers. Used to facilitate particle selection in single particle electron microscopy., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. general, single, particle, picking, macromolecule, size, selection, electron, microscopy, image, transform is listed by: OMICtools NCRR RR17573;
NCRR RR23093
PMID:19374019 THIS RESOURCE IS NO LONGER IN SERVICE http://emg.nysbc.org/redmine/projects/appion/wiki/Appion_Home SCR_016655 Difference of Gaussians (DoG) picker, Difference of Gaussians Picker, Difference of Gaussians picker 2026-09-12 01:00:19 23

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