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https://crf.ucdavis.edu/

Facility is a Biosafety Level III-Plant quarantine located at UC-Davis. Provides a secure environment for research on invasive plant pests. Facility has greenhouse and laboratory space for research on plant pests and pest plants that are required to be maintained at biosecurity level III-plant level by state and/or federal officials.

Proper citation: University of California Davis Contained Research Core Facility (RRID:SCR_028821) Copy   

•   Source: SciCrunch Registry

https://med.unr.edu/research/core-facilities-centers/transgenic-genotyping

Core provides centralized services, consultation, training and technical support to advance transgenic animal genotyping and cardiovascular, metabolic and behavioral phenotyping research.

Proper citation: University of Nevada Reno Transgenic Animal Genotyping and Phenotyping Core Facility (RRID:SCR_028782) Copy   

•   Source: SciCrunch Registry

https://amcat.ucdavis.edu/

Core provides access to analytical instrumentation for the investigation of material properties. Facility specializes in high-resolution imaging and chemical analysis through electron microscopy (SEM, TEM, STEM) and X-ray spectrometry and diffraction (XPS, XRD). Supports interdisciplinary research across engineering, chemistry, physics, and biology by offering comprehensive instrument training, technical support, and scientific expertise tailored to specific experimental systems. Provides resources for sample preparation, instrumentation for nanoscale research, including the only aberration-corrected Scanning Transmission Electron Microscope (STEM) in the Sacramento region, which is equipped with specialized in-situ holders for dynamic experimentation. AMCaT operates Environmental Scanning Electron Microscope (ESEM) allowing for the study of materials under variable pressure and humidity conditions. Provides high-precision XRD systems optimized for crystallography and thin-film analysis.

Proper citation: University of California Davis Advanced Materials Characterization and Testing Laboratory AMCaT Core Facility (RRID:SCR_028819) Copy   

•   Source: SciCrunch Registry

https://research.yale.edu/cores/wcac

Core has a range of instruments for characterization and structure elucidation of chemical and biophysical samples. Mostly equipped in the area of Mass Spectrometry with an addition of NMR and optical spectroscopy.

Proper citation: Yale University West Campus Analytical Core Facility (RRID:SCR_028818) Copy   

•   Source: SciCrunch Registry

https://ouvision.ouhsc.edu/Vision-Cores

Core provides vision researchers with confocal, multiphoton, and macroview fluorescence microscopy together with histology services. Instrumentation includes Olympus FV1200 and FV1000 confocal systems, an Olympus FV1000-MPE multiphoton laser scanning microscope, an Olympus MVX10 macroview fluorescence system for bright-field and fluorescence imaging of flat mount tissues such as retinas and corneas, a Leica cryostat for sectioning, and Nikon E400 and E800 microscopes with dedicated review stations. Histology services include block cassettes, and special staining, and unstained sections.

Proper citation: University of Oklahoma Health Sciences Center Cellular Imaging and Morphometric Analysis Core Facility (RRID:SCR_028873) Copy   

•   Source: SciCrunch Registry

https://ouvision.ouhsc.edu/Vision-Cores

Core provides vision researchers with in vivo imaging and functional analysis of visual system disease models, using instrumentation comparable to that used in clinical ophthalmology so that findings in animal models translate to human disease. Instrumentation includes Diagnosys electroretinography systems, Bioptigen SD optical coherence tomography, optokinetic tracking, Micron III and IV imaging systems with slit lamp and laser attachments, Zeiss operating microscopes with imaging, and specialized environmental housing including dark adaptation, dark rearing, and light damage. The core operates at two campus locations and also provides genotyping services for transgenic and mutant mouse and chick strains.

Proper citation: University of Oklahoma Health Sciences Live Animal Imaging and Analysis Core Facility (RRID:SCR_028872) Copy   

•   Source: SciCrunch Registry

https://research.pathology.wisc.edu/trip-home/

Core provides histopathology services and expertise with human tissue and other species tissues. Offers pathology expertise and infrastructure that allows researchers to perform state-of-the-art spatial biology, cellular, molecular, quantitative and computational pathology analyses. Provides support from project design through downstream analysis. Services include paraffin and frozen tissue processing, embedding, sectioning along with routine and special histological stains, tissue microarray (TMA) creation, immunohistochemistry (IHC) and in situ hybridization (ISH) services, imaging (Aperio, Nuance, Vectra, PhenoImager HT2) and image analysis using HALO/HALO AI and InForm software, human cell line authentication and, spatial and molecular profiling (10X Genomics Visium/Xenium, NanoString GeoMx and nCounter).

Proper citation: University of Wisconsin-Madison Translational Research Initiatives in Pathology Laboratory (TRIPath) Core Facility (RRID:SCR_028868) Copy   

•   Source: SciCrunch Registry

https://sites.udel.edu/mslab/protocols/

Core provides proteomics services including Protein identifications, PTM analysis, quantitative proteomics (label-based and label-free).

Proper citation: University of Delaware Mass Spectrometry Core Facility (RRID:SCR_028862) Copy   

•   Source: SciCrunch Registry

https://borc.unl.edu/

Biomedical and Obesity Research Core (BORC) is a shared research facility providing specialized instrumentation, technical expertise, and research services. BORC supports metabolic phenotyping, cellular and molecular analysis, imaging, extracellular vesicle and nanoparticle characterization, animal behavior and physiology, and other specialized research applications. Provides access to specialized equipment and offers both staff-assisted services and user-operated instrumentation.

Proper citation: University of Nebraska Lincoln Biomedical and Obesity Research Core Facility (RRID:SCR_028863) Copy   

•   Source: SciCrunch Registry

https://research.bidmc.org/biodatabank-core

Core at BIDMC is a physical biorepository of deeply phenotyped human specimens that are linked to clinical diagnoses, a digital databank of omics and histological profiling generated from stored and annotated samples, and a virtual catalogue interface that will facilitate collaborations with the aim to catalyze innovative biomedical research and discovery. Goal of the BioDataBank Core is to build a biobank of Beth Israel Deaconess Medical Center (BIDMC)/BILH patient biospecimens & Omics data from our four Translational Research Hubs that are linked to clinical data for biomedical research directed towards advancing precision medicine. We will diversify the targeted biobank populations by engaging and collaborating with Beth Israel Lahey Health (BILH)-associated community health centers.

Proper citation: Beth Israel Deaconess Medical Center BioDataBank Core Facility (RRID:SCR_028860) Copy   

•   Source: SciCrunch Registry

https://research.bidmc.org/transgenic-core

Transgenic Facility provides services: CRISPR reagent design, Zygote and Cell Microinjection,Embryo Transfer, Embryo/Sperm Cryopreservation, IVF/Embryo thaw for line recovery and importation.

Proper citation: Beth Israel Deaconess Medical Center Transgenic Mouse Core Facility (RRID:SCR_028861) Copy   

•   Source: SciCrunch Registry

https://ouvision.ouhsc.edu/Vision-Cores

Core provides instrumentation and expertise for single-cell analysis in models of ocular development, degeneration, infection, and inflammation. Instrumentation includes a Cytek Aurora full-spectrum flow cytometer, a Cytek Aurora CS cell sorter, and a Luminex 200 multiplex suspension array system, together with an Agilent wound scratch tool, an Agilent Lionheart XL plate imager, and a CellZScope for real-time barrier physiology. Services include assisted and independent instrument use, training, panel and experiment design, sample preparation, and data analysis, with particular expertise in high-autofluorescence ocular tissues.

Proper citation: University of Oklahoma Health Sciences Center Ocular Immunobiology Core Facility (RRID:SCR_028864) Copy   

•   Source: SciCrunch Registry

https://research.udel.edu/regulatory-affairs/animal-subjects/

Core oversees humane animal care, housing, veterinary oversight, and regulatory compliance for all vertebrate research and teaching facilities across campus, partnering with the Institutional Animal Care and Use Committee (IACUC).

Proper citation: University of Delaware Office of Laboratory Animal Medicine Core Facility (RRID:SCR_028794) Copy   

•   Source: SciCrunch Registry

https://mapcore.med.ubc.ca/

Core translates genomic and molecular discoveries into clinical diagnostic and therapeutic applications, focusing heavily on spatial "omics" and advanced tissue analysis. Services include Spatial Profiling: Houses specialized tools like the NanoString GeoMx® Digital Spatial Profiler to map RNA and proteins inside tissue sections; Multiplex Immunofluorescence: Uses platforms like Akoya Opal™ and Leica Cell DIVE™ to image over 40 custom protein markers on a single tissue sample; Histology and Sample Prep: Provides tissue microarray (TMA) construction, laser capture microdissection, microtomy (sample sectioning), and whole-slide digital scanning; Image Analysis: Uses advanced software (such as HALO) to quantify and evaluate tissue biomarker stains.

Proper citation: University of British Columbia Molecular and Advanced Pathology Core Facility (RRID:SCR_028795) Copy   

•   Source: SciCrunch Registry

https://fccl.ku.edu/

Core provides access to flow cytometry and cell sorting instrumentation and expertise. Services include cell sorting and multi-parametric analysis of individual cells in solution. Provides assistance in sample processing, data analysis, instrument training, software support, method and grant assistance, manuscript support, and consulting. BSL-2 facility is equipped with BD FACSymphony S6 and FACSAria Fusion cell sorters, a Cytek Aurora spectral flow cytometer, an Agilent NovoCyte Advanteon conventional flow cytometer, and other supplemental assay instrumentation (Bio-Rad QX600 ddPCR, C.T.L ImmunoSpot). The flow cytometry analyzers provide users with tube- and plate-based, conventional and spectral flow cytometry. The BD FACS instruments allow measurement and sorting of up to 6 resolved populations of cells simultaneously, based on up to 50 parameters of detection using 18 simultaneous fluorochromes. The facility is equipped to handle BSL-2 samples and perform aseptic and single cell sorting into tubes or 96-well plates. The facility provides instrument training for users who desire to become self-operators of the facility instruments. The FCC will equip CBID researchers with tools directly applicable to infectious disease research, such as identifying and characterizing infectious agents such as bacteria and parasites, quantification and sorting of cells infected with microbial pathogens, and assessing chemical probe efficacy against infectious agents.

Proper citation: University of Kansas Flow Cytometry Core Facility (RRID:SCR_028833) Copy   

•   Source: SciCrunch Registry

https://cobre-spm.tulane.edu/research-core

Core provides research infrastructure, data resources, and analytical expertise to support studies in sex-based precision medicine. Facilitates access to and analysis of large-scale clinical, electronic health record, genomic, and population datasets, including eMERGE and the All of Us Research Program, and assists investigators with their own research data. Core provides expertise in biomedical informatics, biostatistics, statistical genetics, bioinformatics, data management, artificial intelligence and machine learning, and implementation science. Through consultation and collaborative support, the SPMRC assists investigators with study design, data acquisition and management, analytical approaches, interpretation of results, and development of rigorous, reproducible research addressing sex differences in health and disease.

Proper citation: Tulane University Sex-Based Precision Medicine Research Core Facility (RRID:SCR_028834) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/pru/

Core develops and utilizes preclinical and in-vivo systems for the testing of novel cancer therapeutics. Provides technical services and collaboration with the IACUC, DCM, and other core facilities on campus for labs that utilize small laboratory animals in their research. Offers technical expertise with small laboratory animal models for reproducibility of research at UNC, and complete study management as well as individual services. Technicians are experienced, highly skilled, and maintain American Association for Laboratory Animal Science Technician/Technologist (AALAS) certifications.

Proper citation: University of North Carolina at Chapel Hill UNC Preclinical Research Unit Core Facility (RRID:SCR_028832) Copy   

•   Source: SciCrunch Registry

https://medicine.tulane.edu/centers-institutes/ctrii/nextgen-sequencing-core

Core provides Illumina next-generation sequencing and single-cell RNA sequencing to support gene expression and genomic research. Core services include Illumina Sequencing: High-throughput, fast-turnaround genomic sequencing runs; Single-Cell Transcriptomics: Single-cell RNA sequencing (scRNA-seq) chemistries to map gene expression at individual cell resolution; Gene Expression Analysis: Support for studies examining transcriptional changes, host resistance mechanisms, and inflammatory responses.

Proper citation: Tulane University School of Medicine CTRII NextGen Sequencing Core Facility (RRID:SCR_028790) Copy   

•   Source: SciCrunch Registry

https://icemhh.pbrc.hawaii.edu/micro/

Core provides access to instrumentation, training, flow cytometry services, and advanced microscopy (light, epifluorescence, confocal and laser tweezers/microdissection microscopy, and scanning and transmission electron microscopy) on a recharge basis. Clients may be trained to use instruments independently, elect to have a technician operate the instruments in their presence, or may contract the technician to conduct the work and provide finished products. Provides workshops, demonstrations, and laboratory sessions for UH undergraduate and graduate courses, staff, and faculty.

Proper citation: University of Hawaii at Manoa Integrative Center for Environmental Microbiomes and Human Health Microscopy Imaging Center for Research through Observation MICRO Imaging Core Facility (RRID:SCR_028841) Copy   

•   Source: SciCrunch Registry

https://csuveterinaryhealth.org/veterinary-diagnostic-laboratories/next-generation-sequencing-core/

Core provides consultation, educational trainings, quality control, select library preparation, and sequencing services. Core operates Illumina and Oxford Nanopore Technologies instruments.

Proper citation: Colorado State University Veterinary Health System Next Generation Sequencing Core Facility (RRID:SCR_028842) Copy   

•   Source: SciCrunch Registry