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https://genomicscore.vai.org

Provides services including Next Generation Sequencing, single cell Genomics, and Spatial Transcriptomics facility. Provides experimental design support, library generation, and Illumina and Nanopore Sequencing.

Proper citation: Van Andel Institute Genomics Core Facility (RRID:SCR_022913) Copy   

•   Source: SciCrunch Registry

https://pbc.vai.org/

Pathology and Biorepository Core (PBC) integrates anatomic pathology expertise with biorepository and biospecimen science. It provides emphasis on high-quality biospecimens and interpretable results to validate experimental models and extend them to clinical samples. The PBC offers a comprehensive range of biospecimen services, including histology, pathology, and biospecimen processing and storage.

Proper citation: Van Andel Institute Pathology and Biorepository Core Facility (RRID:SCR_022912) Copy   

•   Source: SciCrunch Registry

http://www.hawaii.edu/pceidr

Research on microbial agents, which cause lethal diseases in humans and for which effective drugs or preventive vaccines are not available, must be conducted by well-trained investigators in specially built, well-maintained laboratories. Core provides the triad of service, research and development, and education and training.

Proper citation: University of Hawaii at Manoa ABSL3/BSL3 Biocontaminant Core Facility (RRID:SCR_022878) Copy   

•   Source: SciCrunch Registry

https://med.virginia.edu/biorepository-and-tissue-research-facility/

Core is involved in procurement and processing of human tissue and other biospecimens for basic, translational, and clinical research.Provides laboratory support services for clinical trials, tissue samples from remnant surgical resection and autopsy specimens linked to clinicopathologic data while maintaining patient confidentiality. Provides biorepository of human specimens.Offers advanced histology services including multi color immunohistochemistry, in situ hybridization, tissue microarrays, slide scanning, computerized image analysis, NanoString spatial profiling.

Proper citation: University of Virginia School of Medicine Biorepository and Tissue Research Core Facility (RRID:SCR_022971) Copy   

•   Source: SciCrunch Registry

https://www.janelia.org/support-team/quantitative-genomics

Provides services to anything related to genomic analysis, such as RNAseq, genome sequencing, ATACseq etc, from experiment design all the way down to data analysis.Provides expert services for cell isolation, transcriptome and epigenetic profiling, and de novo genome assembly using next generation sequencing platforms from Illumina.

Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Quantitative Genomics Core Facility (RRID:SCR_022694) Copy   

•   Source: SciCrunch Registry

https://nyumc.ilab.agilent.com/sc/5998/research_software_engineering_core

Core is resource launched by NYU Langone, based in Information Technology department in close collaboration with NYU Grossman School of Medicine.Used to design, develop, optimize, and customize software to accelerate research. Requires iLab log in.

Proper citation: New York University Langone Medical Center Research Software Engineering Core Facility (RRID:SCR_023022) Copy   

•   Source: SciCrunch Registry

https://www.tamucet.org/

Offers services to researchers looking for collaborators or contractors for their educational or training projects.Offers development tools and hosting services to educators creating their own online training resources.

Proper citation: Texas A and M University Center for Educational Technologies Core Facility (RRID:SCR_022691) Copy   

•   Source: SciCrunch Registry

https://www.chumontreal.qc.ca/crchum/plateformes-services/imagerie-cellulaire

Optical and fluorescence microscopy facility. Provided instruments include range of microscopes from regular brightfield microscopes to high performence LSM900- Airyscan confocal microscope. Provides Image Analysis with Imaris Full Spectrum and ClearDeconvolution software.

Proper citation: University of Montreal CRCHUM Cell Imaging Core Facility (RRID:SCR_022726) Copy   

•   Source: SciCrunch Registry

https://eqnmr.med.harvard.edu

Offers services in fragment based screening and drug discovery, characterization and QC of biologics and biosimilar drugs, metabolomics, protein NMR, small molecule NMR, and NMR of natural products. Offers 400-700MHz systems, many with cryogenic probes.

Proper citation: Harvard Medical School Biomolecular Nuclear Magnetic Resonance Core Facility (RRID:SCR_022967) Copy   

•   Source: SciCrunch Registry

https://www.umassmed.edu/scope/

Offers tools and expertise for quantitative microscopy techniques including super resolution imaging, multi photon intravital and live tissue imaging, confocal microscopy, and high speed time lapse imaging.Offers commercial and custom built microscopes, training and access to light microscopes, imaging services including whole slide scanning, MERFISH spatial transcriptomics, NanoString GeoMx DSP services, and image analysis support. Wet lab facilities, including cell culture, are also available at this BL2 facility. Imaging at BSL3 is available upon request.Offers remote imaging and data analysis sessions, including remote control of all instruments and workstations. All users are trained individually prior to use of the SCOPE equipment and workstations.

Proper citation: University of Massachusetts Medical School Sanderson Center for Optical Experimentation Core Facility (RRID:SCR_022721) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/metabolite/index.php

Provides technologies that enable both qualitative (defining all components of metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems.Provides sensitive mass spectrometry coupled with liquid chromatography and gas chromatography for precise sample analysis. Empowers researchers with new technologies, methods development, sample analysis, expert training, and consultation.

Proper citation: Purdue University West Lafayette Metabolite Profiling Core Facility (RRID:SCR_022728) Copy   

•   Source: SciCrunch Registry

https://irp.drugabuse.gov/organization/core-facilities/genetic-engineering/

Provides support to NIDA-IRP researchers by facilitating studies of brain function under physiological and pathological conditions through developing and producing genetic tools capable of modulating and monitoring molecules, cells and circuits in nervous system.Provided services include custom design and/or production of viral vectors/nanoparticles;in vitro molecular and cell biology services; consultation and training.

Proper citation: National Institute on Drug Abuse Genetic Engineering and Viral Vector Core Facility (RRID:SCR_022969) Copy   

•   Source: SciCrunch Registry

https://bioimaging.dbi.udel.edu/flow-cytometry-core-2/

Facility, located at the University of Delaware Main campus (UD) in Newark, Delaware, provides flow cytometry and hematology services. Facility is equipped with 15-color FACSAria Fusion high-speed cell sorters,BD Rhapsody Express Cell Processing Unit,VetScan HM5c veterinary hematology analyzer, Nexcelom Cellometer Vision cell counter, Zeiss Axiovert 200 inverted fluorescent microscope,Thermo Shandon Cytospin 4 & a Beckman Spinchron DLX centrifuge,General Laboratory facilities for Mammalian Cell Culture and Sample preparation,Laminar flow BSL-2 biosafety cabinets, microscopes and centrifuges.

Proper citation: University of Delaware Flow Cytometry Core Facility (RRID:SCR_022861) Copy   

•   Source: SciCrunch Registry

https://cbc.arizona.edu/rss/glass-facility

Provides full service facility for design and fabrication of specialized scientific glassware as well as repairs and modifications of existing glassware.

Proper citation: University of Arizona CBC Glassblowing Core Facility (RRID:SCR_023036) Copy   

•   Source: SciCrunch Registry

https://cbc.arizona.edu/rss/electronics-facility

Supporting the research community through troubleshooting, repair and new designs for electronic instrumentation, equipment and experiments.

Proper citation: University of Arizona CBC Electronics Core Facility (RRID:SCR_023035) Copy   

•   Source: SciCrunch Registry

https://cbc.arizona.edu/rss/machine-shop

Provides full service precision machine shop specializing in design and construction of custom equipment for scientific research and teaching.

Proper citation: University of Arizona CBC Machine Shop Core Facility (RRID:SCR_023034) Copy   

•   Source: SciCrunch Registry

https://www.nebraskamed.com/neurological-care/meg-center

Equipped with magnetoencephalography (MEG) scanner to detect immediate changes in electrical brain activity. Provides 306 channel whole head MEG system (TRIUX, Neo, MEGin) and 128 channels EEG amplifier.MEG helmet does coverage for whole cortex, 1220 cm2. MEG system has three measurement positions:supine, lower and upper seated. MEG system is housed within magnetic shielded room equipped with active shielding and automated helium recycler.

Proper citation: University of Nebraska Medical Center UNMC MEG Core Facility (RRID:SCR_023033) Copy   

•   Source: SciCrunch Registry

https://nyumc.ilab.agilent.com/service_center/show_external/4296?name=experimental-pathology-research-laboratory

Core provides services, access to instruments, and training to facilitate production of animal tissue samples for morphological and molecular analyses. Supports multiplex immunofluorescence staining, RNA in situ hybridization (ISH), and imaging analysis. Services include tissue preparation, processing, and sectioning, as well as histochemistry and immunohistochemistry of fresh, frozen, and fixed animal tissues, can optimize and validate commercial or proprietary antibodies for chromogenic or fluorescence-based immunohistochemistry including seven-color multiplexing.Provides access to database listing antibodies that have been tested in lab to date and are currently in stock.Offers basic imaging resources and digital whole-slide scanning of stained tissue sections, which allows researchers to view their slides online at their convenience.Researchers can also rent our self-service instruments. These include embedding station, microtome, cryostat, and vibratome. Provides access to brightfield and fluorescence upright and dissecting microscopes,laser capture microdissection scope, and high-throughput multispectral imaging system.To reserve time on instrument, faculty, staff, and investigators must be registered in iLab.

Proper citation: New York University School of Medicine Langone Health Experimental Pathology Research Laboratory Core Facility (RRID:SCR_017928) Copy   

•   Source: SciCrunch Registry

https://ki-sbc.mit.edu/dsmi

Core provides central hub to help leverage bioinformatics and data science methods in research projects. Services include Transcriptomics: bulk RNA-Seq, single-cell RNA-Seq, and spatial RNA-Seq; Genomics: SNP, structural variants (SV), and copy number variation (CNV) analyses; Regulatory genomics: ChIP-Seq, ATAC-Seq, CUT&RUN, and Hi-C; Functional genomics: CRISPR-based loss-of-function screens;Image and metadata analysis: AI/ML-based approaches including knowledge graphs. Offers training, education, collaboration, consultation,custom guidance on study design and analysis approaches. Provides classroom and custom training sessions on computational, data science, bioinformatics topics, tailored workshops for requested specialized topics. Offers technical infrastructure and support, computing resource optimization and facilitation, bioinformatics software deployment (conda environments and Docker containers), version control and reproducible science (Git repositories), data management support and submission to public repositories.

Proper citation: Koch Institute at MIT Data Science and Multimodal Integration Core Facility (RRID:SCR_017894) Copy   

•   Source: SciCrunch Registry

https://coreimmunology.ucsf.edu/services

Provides immunology assays, expert consultation, and education to UCSF and global research community. CIL specializes in developing immunology research tools, and initiating and stimulating innovative research projects to address emerging questions in immunologic diseases including HIV pathogenesis.Services include:Isolation of PBMC for staining, cell sorting, or viable cryopreservation;Isolation of mucosal mononuclear cells (MMC) from mucosal tissue biopsies;Immunomagnetic bead isolation of untouched cell populations for functional studies;Immunophenotyping of whole blood, PBMC, MMC and cerebrospinal fluid for: NK, B and T cells percentages, and their subsets, including maturation, trafficking, senescence, activation, in vivo proliferation and chemokine receptor expression;Flow cytometric functional assays, including NK cell function, antigen-specific CD4+ and CD8+ T cell cytokine expression, degranulation and proliferation;Evaluation of T cell signaling by phosflow using monoclonal antibodies specific for phosphorylated protein;Training and Support;Flow Cytometry Training Course;Three-hour lecture and lab course designed to cover basics of flow cytometry including:Fluorescence emission and detection,Fluidics,Operation,Panel design,Controls.

Proper citation: University of California at San Francisco Immunology Lab Core Facility (RRID:SCR_017906) Copy   

•   Source: SciCrunch Registry