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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://bioconductor.org/packages/2.11/bioc/html/flowPhyto.html
An R package that performs aggregate statistics on virtually unlimited collections of raw flow cytometry files and provides a memory efficient, parallelized solution for analyzing high-throughput flow cytometric data.
Proper citation: flowPhyto (RRID:SCR_002183) Copy
http://www.bioconductor.org/packages/devel/bioc/html/BEAT.html
Software that implements all bioinformatics steps required for the quantitative, high-resolution analysis of DNA methylation patterns from bisulfite sequencing data.
Proper citation: BEAT (RRID:SCR_002387) Copy
http://www.bioconductor.org/packages/release/bioc/html/CAMERA.html
A Bioconductor package integrating algorithms to extract compound spectra, annotate isotope and adduct peaks, and propose the accurate compound mass even in highly complex data.
Proper citation: CAMERA - Collection of annotation related methods for mass spectrometry data (RRID:SCR_002466) Copy
http://www.bioconductor.org/packages/devel/bioc/html/MethylAid.html
Software for visual and interactive quality control of large Illumina 450k data sets. Bad quality samples are detected using sample-dependent and sample-independent controls present on the array and user adjustable thresholds. In depth exploration of bad quality samples can be performed using several interactive diagnostic plots of the quality control probes present on the array. Furthermore, the impact of any batch effect provided by the user can be explored.
Proper citation: MethylAid (RRID:SCR_002659) Copy
http://www.bioconductor.org/packages/devel/bioc/html/CGHnormaliter.html
Software for normalization and centralization of array comparative genomic hybridization (aCGH) data with imbalanced aberrations. The algorithm uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs).
Proper citation: CGHnormaliter (RRID:SCR_002936) Copy
http://www.bioconductor.org/packages/release/bioc/html/chimera.html
A Bioconductor package that organizes, annotates, analyses and validates fusions reported by different fusion detection tools. The current implementation can deal with output from bellerophontes, chimeraScan, deFuse, fusionCatcher, FusionFinder, FusionHunter, FusionMap, mapSplice, Rsubread, tophat-fusion, tophat-fusion-post and STAR. The core of Chimera is a fusion data structure that can store fusion events detected with any of the aforementioned tools.
Proper citation: Chimera (RRID:SCR_002959) Copy
http://www.bioconductor.org/packages/release/bioc/html/triplex.html
Software package that provides functions for identification and visualization of potential intramolecular triplex patterns in DNA sequence. The main functionality is to detect the positions of subsequences capable of folding into an intramolecular triplex (H-DNA) in a much larger sequence. The potential H-DNA (triplexes) should be made of as many canonical nucleotide triplets as possible. The package includes visualization showing the exact base-pairing in 1D, 2D or 3D.
Proper citation: Triplex (RRID:SCR_003061) Copy
http://bioinfo.cipf.es/noiseq/doku.php?id=start
Software used for the identification of differentially expressed genes from count data or previously normalized count data. It empirically models the noise distribution of count changes by contrasting fold-change differences (M) and absolute expression differences (D) for all the features in samples within the same condition. This reference distribution is then used to assess whether the M-D values computed between two conditions for a given gene is likely to be part of the noise or represent a true differential expression.
Proper citation: NOISeq (RRID:SCR_003002) Copy
https://bioconductor.org/packages//2.13/bioc/html/virtualArray.html
Software package that permits the user to combine raw data of different microarray platforms into one virtual array. It consists of several functions that act subsequently in a semi-automatic way. Doing as much of the data combination and letting the user concentrate on analyzing the resulting virtual array.
Proper citation: virtualArray (RRID:SCR_001361) Copy
http://www.bioconductor.org/packages/release/bioc/html/stepNorm.html
Software for stepwise normalization functions for cDNA microarray data.
Proper citation: stepNorm (RRID:SCR_001359) Copy
http://www.bioconductor.org/packages/release/bioc/html/rama.html
Software package for robust estimation of cDNA microarray intensities with replicates. It uses a Bayesian hierarchical model for the robust estimation. Outliers are modeled explicitly using a t-distribution, and the model also addresses classical issues such as design effects, normalization, transformation, and nonconstant variance.
Proper citation: RAMA (RRID:SCR_001358) Copy
http://www.bioconductor.org/packages/release/bioc/html/MANOR.html
Software packqge for importation, normalization, visualization, and quality control functions to correct identified sources of variability in array-CGH (Comparative genomic hybridization) experiments.
Proper citation: MANOR (RRID:SCR_001305) Copy
http://www.bioconductor.org/packages/release/bioc/html/dyebias.html
Software package using the GASSCO method for correcting for slide-dependent gene-specific dye bias.
Proper citation: dyebias (RRID:SCR_001308) Copy
http://www.bioconductor.org/packages/release/bioc/html/limmaGUI.html
Software package for a Graphical User Interface for the limma Microarray package.
Proper citation: limmaGUI (RRID:SCR_001306) Copy
http://www.bioconductor.org/packages/release/bioc/html/ffpe.html
Software to identify low-quality data using metrics developed for expression data derived from Formalin-Fixed, Paraffin-Embedded (FFPE) data. Also a function for making Concordance at the Top plots (CAT-plots).
Proper citation: ffpe (RRID:SCR_001307) Copy
http://www.bioconductor.org/packages/release/bioc/html/ACME.html
A set of tools for analysing tiling array ChIP/chip, DNAse hypersensitivity, or other experiments that result in regions of the genome showing enrichment. It does not rely on a specific array technology (although the array should be a tiling array), is very general (can be applied in experiments resulting in regions of enrichment), and is very insensitive to array noise or normalization methods. It is also very fast and can be applied on whole-genome tiling array experiments quite easily with enough memory.
Proper citation: ACME (RRID:SCR_001464) Copy
http://www.bioconductor.org/packages/release/bioc/html/CoGAPS.html
Software that infers biological processes which are active in individual gene sets from corresponding microarray measurements. It achieves this inference by combining a MCMC matrix decomposition algorithm (GAPS) with a novel statistic inferring activity on gene sets.
Proper citation: CoGAPS (RRID:SCR_001479) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowFP.html
A Bioconductor software package for fingerprint generation of flow cytometry data, used to facilitate the application of machine learning and datamining tools for flow cytometry.
Proper citation: flowFP (RRID:SCR_001537) Copy
https://www.bioconductor.org/packages//2.7/bioc/html/plateCore.html
Software that provides basic S4 data structures and routines for analyzing plate based flow cytometry data.
Proper citation: plateCore (RRID:SCR_001743) Copy
http://www.bioconductor.org/packages/release/bioc/html/SLqPCR.html
Software functions for analysis of real-time quantitative PCR data at SIRS-Lab GmbH.
Proper citation: SLqPCR (RRID:SCR_001669) Copy
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