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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
OmicCircos
 
Resource Report
Resource Website
50+ mentions
OmicCircos (RRID:SCR_003292) software resource An R software application and package used to generate high-quality circular plots for visualizing genomic variations, including mutation patterns, copy number variations (CNVs), expression patterns, and methylation patterns. standalone software, unix/linux, mac os x, windows, r, annotation, statistical method, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:24526832 Free, Available for download, Freely available OMICS_04659 http://www.bioconductor.org/packages/release/bioc/html/OmicCircos.html SCR_003292 OmicCircos: High-quality circular visualization of omic data 2026-09-12 12:55:55 83
nSolver Analysis Software
 
Resource Report
Resource Website
100+ mentions
nSolver Analysis Software (RRID:SCR_003420) nSolver Analysis Software data processing software, software application, software resource Data analysis software program that offers nCounter users the ability to QC, normalize, and analyze data without having to purchase additional software packages. normalization, analysis, ncounter, os x, windows, quality control is listed by: OMICtools Restricted OMICS_02309 https://nanostring.app.box.com/v/nSolver-AdvancedAnalysis, https://nanostring.com/products/ncounter-analysis-system/ncounter-analysis-solutions/nsolver-data-analysis-support/ SCR_003420 2026-09-12 12:55:58 405
NAPPA
 
Resource Report
Resource Website
10+ mentions
NAPPA (RRID:SCR_003419) NAPPA software resource Software that enables the processing and normalization of the standard mRNA data output from the Nanostring nCounter software. normalization, processing, nanostring, mirna, mrna, os x, windows is listed by: OMICtools GNU General Public License, v3 OMICS_02310 SCR_003419 NAPPA: Performs the processing and normalisation of Nanostring miRNA and mRNA data 2026-09-12 12:55:57 12
Polyester
 
Resource Report
Resource Website
100+ mentions
Polyester (RRID:SCR_003602) data analysis software, data processing software, simulation software, software application, software resource An R package designed to simulate RNA sequencing experiments with differential transcript expression. Given a set of annotated transcripts, it will simulate the steps of an RNA-seq experiment (fragmentation, reverse-complementing, and sequencing) and produce files containing simulated RNA-seq reads. Simulated reads can be analyzed using a choice of downstream analysis tools. Polyester has a built-in wrapper function to simulate a case/control experiment with differential transcript expression and biological replicates. Users are able to set the levels of differential expression at transcripts of their choosing. This means they know which transcripts are differentially expressed in the simulated dataset, so accuracy of statistical methods for differential expression detection can be analyzed. Polyester offers several unique features: * Built-in functionality to simulate differential expression at the transcript level * Ability to explicitly set differential expression signal strength * Simulation of small datasets, since large RNA-seq datasets can require lots of time and computing resources to analyze * Generation of raw RNA-seq reads, as opposed to alignments or transcript-level abundance estimates * Transparency/open-source code standalone software, unix/linux, mac os x, windows, r, rna-seq is listed by: OMICtools OMICS_04272 SCR_003602 2026-09-12 12:56:00 491
BrainVisa Morphology extensions
 
Resource Report
Resource Website
1+ mentions
BrainVisa Morphology extensions (RRID:SCR_013248) BrainVisa Morphology extensions software resource An extension projects providing computational tools for performing regional morphological measurements to assess groupwise differences and track morphological changes during maturation and aging. The extensions include computation of regional GM thickness, 3D gyrification index, sulcal lenght and depth and sulcal span. These tools are distributed in the form of plugins for a popular analysis package BrainVisa analyze, c++, image display, linux, macos, microsoft, morphology, magnetic resonance, nifti, posix/unix-like, quantification, shape analysis, software, visualization, windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: BrainVISA / Anatomist
is related to: INCF Software Center
Artistic License nlx_155716 http://www.nitrc.org/projects/brainvisa_ext SCR_013248 2026-09-12 12:58:00 1
breseq
 
Resource Report
Resource Website
100+ mentions
breseq (RRID:SCR_010810) breseq software resource A computational pipeline for finding mutations relative to a reference sequence in short-read DNA re-sequencing data intended for haploid microbial genomes. windows, genomics, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
OMICS_00298, biotools:breseq https://barricklab.org/twiki/bin/view/Lab/ToolsBacterialGenomeResequencing, https://bio.tools/breseq SCR_010810 breseq - Determine mutations in evolved microbes from next-generation sequencing data 2026-09-12 12:57:23 474
SimTKCore
 
Resource Report
Resource Website
SimTKCore (RRID:SCR_008268) SimTKCore simulation software, software application, software resource SimTK Core is one of the two packages that together constitute SimTK, the biosimulation toolkit from the Simbios Center. The other major component of SimTK is OpenMM which is packaged separately. This SimTK Core project collects together all the binaries needed for the various SimTK Core subprojects. These include Simbody, Molmodel, Simmath (including Ipopt), Simmatrix, CPodes, SimTKcommon, and Lapack. See the individual projects for descriptions. SimTK brings together in a robust, convenient, open source form the collection of highly-specialized technologies necessary to building successful physics-based simulations of biological structures. These include: strict adherence to an important set of abstractions and guiding principles, robust, high-performance numerical methods, support for developing and sharing physics-based models, and careful software engineering. Accessible High Performance Computing We believe that a primary concern of simulation scientists is performance, that is, speed of computation. We seek to build valid, approximate models using classical physics in order to achieve reasonable run times for our computational studies, so that we can hope to learn something interesting before retirement. In the choice of SimTK technologies, we are focused on achieving the best possible performance on hardware that most researchers actually have. In today''s practice, that means commodity multiprocessors and small clusters. The difference in performance between the best methods and the do-it-yourself techniques most people use can be astoundingeasily an order of magnitude or more. The growing set of SimTK Core libraries seeks to provide the best implementation of the best-known methods for widely used computations such as: Linear algebra, numerical integration and Monte Carlo sampling, multibody (internal coordinate) dynamics, molecular force field evaluation, nonlinear root finding and optimization. All SimTK Core software is in the form of C++ APIs, is thread-safe, and quietly exploits multiple CPUs when they are present. The resulting pre-built binaries are available for download and immediate use. Audience: Biosimulation application programmers interested in including robust, high-performance physics-based simulation in their domain-specific applications. computational algorithm, high-performance, linear algebra, numerical integration, numerical method, optimization, monte carlo sampling, multibody dynamics, molecular force field evaluation, nonlinear root finding, optimizing, cpodes, simbody, ipopt, molmodel, mit license, linux, mac os x, windows is listed by: Biositemaps
has parent organization: Stanford University; Stanford; California
has parent organization: Simtk.org
NIGMS U54 GM072970 PMID:20107615 nif-0000-23310 SCR_008268 2026-09-12 12:57:01 0
BioSig: An Imaging Bioinformatics System for Phenotypic Analysis
 
Resource Report
Resource Website
100+ mentions
BioSig: An Imaging Bioinformatics System for Phenotypic Analysis (RRID:SCR_008428) BioSig data processing software, image processing software, software application, software library, software resource, software toolkit Software library for processing of electroencephalogram (EEG) and other biomedical signals like electroencephalogram (EEG), electrocorticogram (ECoG), electrocardiogram (ECG), electrooculogram (EOG), electromyogram (EMG), respiration, and so on. Biosig contains tools for quality control, artifact processing, time series analysis, feature extraction, classification and machine learning, and tools for statistical analysis. Many tools are able to handle data with missing values (statistics, time series analysis, machine learning). Another feature is that more then 40 different data formats are supported, and a number of converters for EEG,, ECG and polysomnography are provided. Biosig has been widely used for scientific research on EEG-based BraiN-Computer Interfaces (BCI), sleep research, and ECG and HRV analysis. It provides software interfaces several programming languages (C, C++, Matlab/Octave, Python), and it provides also an interactive viewing and scoring software for adding, and editing of annotations, markers and events. application, autocorrelation, bsd, c, c++, connectivity analysis, correlation, cross-correlation, directed transfer analysis, discriminant analysis, domain independent, eeg, meg, electrocorticography, end event related potential, format conversion, german, gnome, granger causality, information theory, kde, linux, matlab, microsoft, multivariate analysis, partial directed coherence, posix/unix-like, python, regression, spectral analysis, statistical operation, temporal transformation, time domain analysis, win32 (ms windows), windows, electrocorticogram, electrocardiogram, electrooculogram, electromyogram, respiration, signal, processing, biosignal is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
has parent organization: Lawrence Berkeley National Laboratory
DOI:10.1109/MC.2008.407 Free, Available for download, Freely available nif-0000-30190 http://www.nitrc.org/projects/biosig, https://sources.debian.org/src/biosig-tools/ SCR_008428 2026-09-12 12:57:04 165
BrainSolution
 
Resource Report
Resource Website
BrainSolution (RRID:SCR_009447) BrainSolution data processing software, image analysis software, segmentation software, software application, software resource A collection of tools for MRI T1 brain image segmentation in the Windows environment. It helps construct a complete pipeline with necessary preprocessing and postprocessing procedures besides brainparser, the core program of our fast brain segmentation. The execution of the whole pipeline can be completed in 2 hours with good segmentation results. Execution requires: FSL analyze, c++, console (text based), labeling, linux, microsoft, magnetic resonance, posix/unix-like, region of interest, segmentation, sh/bash, unix shell, windows, windows nt/2000, windows vista, workflow is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Laboratory of Neuro Imaging
LONI Software License nlx_155591 SCR_009447 2026-09-12 12:57:12 0
NCIGT Fast Imaging Library
 
Resource Report
Resource Website
NCIGT Fast Imaging Library (RRID:SCR_009609) Fast Imaging Library data processing software, image analysis software, image reconstruction software, software application, software resource, software toolkit This software provides algorithms for the reconstruction of raw MR data. In particular, it supports the reconstruction of accelerated data acquisitions where k-space is subsampled and the Fourier domain encoding is complemented by temporal encoding, spatial encoding, or and/or a constrained reconstruction. This library of functions provides a number of reconstruction algorithms that accurately employ advanced MR imaging methods including: UNFOLD; parallel imaging methods such as SENSE and GRAPPA; Homodyne processing of partial-Fourier data, and gradient field inhomogeneity correction (gradwarp); EPI Nyquist Ghost correction and ramp-sampling gridding. The target audience is research groups who may be interested in exploring or employing advanced MR reconstruction techniques, but don't have the necessary expertise in-house. Inquires may be directed to: ncigt-imaging-toolkit -at- bwh.harvard.edu algorithm, reusable library, application, c, console (text based), image reconstruction, linux, macos, microsoft, magnetic resonance, posix/unix-like, windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) NC-ICT Fast Imaging Library Contribution and Software License, Http://www.nitrc.org/include/glossary.php#569 nlx_155822 http://www.nitrc.org/projects/igt_fil SCR_009609 NC-IGT Fast Imaging Library, National Center for Image-Guided Therapy Fast Imaging Library 2026-09-12 12:57:14 0
Mango
 
Resource Report
Resource Website
100+ mentions
Mango (RRID:SCR_009603) Mango data processing software, data visualization software, image analysis software, image processing software, software application, software resource A viewer for medical research images that provides analysis tools and a user interface to navigate image volumes. There are three versions of Mango, each geared for a different platform: * Mango ? Desktop ? Mac OS X, Windows, and Linux * webMango ? Browser ? Safari, Firefox, Chrome, and Internet Explorer * iMango ? Mobile ? Apple iPad Key Features: * Built-in support for DICOM, NIFTI, Analyze, and NEMA-DES formats * Customizable: Create plugins, custom filters, color tables, file formats, and atlases * ROI Editing: Threshold and component-based tools for painting and tracing ROIs * Surface Rendering: Interactive surface models supporting cut planes and overlays * Image Registration: Semi-automatic image coregistration and manual transform editing * Image Stacking: Threshold and transparency-based image overlay stacking * Analysis: Histogram, cross-section, time-series analysis, image and ROI statistics * Processing: Kernel and rank filtering, arithmetic/logic image and ROI calculators analyze, atlas application, console (text based), dicom, gifti, java, linux, macos, microsoft, magnetic resonance, nifti, os independent, platform, posix/unix-like, quantification, region of interest, registration, rendering, segmentation, spatial transformation, statistical operation, sunos/solaris, surface analysis, temporal transformation, visualization, volumetric analysis, web environment, win32 (ms windows), windows, windows vista, windows xp is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Texas Health Science Center at San Antonio; Texas; USA
NIBIB P01-EB01955;
NIBIB R01-EB015314-01a1;
NIMH R01-MH074457
Free nlx_155804 http://www.nitrc.org/projects/mango SCR_009603 Multi-image Analysis GUI 2026-09-12 12:57:14 491
Pipeline System for Octave and Matlab
 
Resource Report
Resource Website
1+ mentions
Pipeline System for Octave and Matlab (RRID:SCR_009637) PSOM data processing software, software application, software library, software resource, software toolkit, workflow software A lightweight software library to manage complex multi-stage data processing. A pipeline is a collection of jobs, i.e. Matlab or Octave codes with a well identified set of options that are using files for inputs and outputs. To use PSOM, the only requirement is to generate a description of a pipeline in the form of a simple Matlab / Octave structure. PSOM then automatically offers the following services: * Run jobs in parallel using multiple CPUs or within a distributed computing environment. * Generate log files and keep track of the pipeline execution. These logs are detailed enough to fully reproduce the analysis. * Handle job failures : successful completion of jobs is checked and failed jobs can be restarted. * Handle updates of the pipeline : change options or add jobs and let PSOM figure out what to reprocess ! reusable library, linux, macos, matlab, microsoft, posix/unix-like, windows, workflow, octave, pipeline is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Montreal; Quebec; Canada
PMID:22493575 MIT License nlx_155924 http://www.nitrc.org/projects/psom SCR_009637 2026-09-12 12:57:14 3
NordicNeuroLab
 
Resource Report
Resource Website
50+ mentions
NordicNeuroLab (RRID:SCR_009632) NNL commercial organization From state of the art post-processing and visualization software for BOLD, Diffusion / DTI, and Perfusion / DCE imaging to fMRI hardware for audio and visual stimulation, eye tracking, and patient response collection, they provide products and solutions that define the field of functional MR imaging. They are dedicated to bringing the most advanced neuro-imaging tools to market while making functional MRI programs easy to implement. Through collaboration with research and clinical teams from both academic and medical centers, MR system manufacturers, and third party vendors they develop and manufacture hardware and software solutions that meet the needs of very experienced centers while developing training programs to make fMRI easy to adopt for more novice users. Their products are used around the world by researchers and clinicians alike. analyze, ascii, dicom, diffusion mr fiber tracking, experiment control, eye tracking, fiber tracking, haemodynamic response, hardware, microsoft, magnetic resonance, nifti, perfusion, physiological recording, scanner, stimulus presentation, temporal curve fitting, temporal transformation, tractography, windows, windows vista, windows xp, fmri, post-processing, visualization, bold, diffusion, dti, perfusion, dce, audio stimulation, visual stimulation, eye tracking, patient response, clinical, eye tracking device is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Commercial nlx_155905 http://www.nitrc.org/projects/nnl SCR_009632 2026-09-12 12:57:14 57
eConnectome
 
Resource Report
Resource Website
10+ mentions
eConnectome (RRID:SCR_009618) eConnectome data processing software, image analysis software, image processing software, software application, software resource An open-source MATLAB software package for imaging brain functional connectivity from electrophysiological signals. It provides interactive graphical interfaces for EEG/ECoG/MEG preprocessing, source estimation, connectivity analysis and visualization. Connectivity from EEG/ECoG/MEG can be mapped over sensor and source domains. This package is designed for use by researchers in neuroscience, psychology, cognitive science, clinical neurophysiology, neurology and other disciplines. The graphical interface-based platform requires little programming knowledge or experience with MATLAB. eConnectome is developed by the Biomedical Functional Imaging and Neuroengineering Laboratory at the University of Minnesota, directed by Dr. Bin He. The visualization module is jointly developed with Drs. Fabio Babiloni and Laura Astolfi at the University of Rome La Sapienza. eeg, meg, electrocorticography, forward - inverse, matlab, microsoft, modeling, multivariate analysis, region of interest, segmentation, statistical operation, visualization, windows, windows xp is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Minnesota Twin Cities; Minnesota; USA
NIBIB RO1 EB006433;
NIBIB RO1 EB007920
GNU General Public License nlx_155844 http://www.nitrc.org/projects/econnectome SCR_009618 Electrophysiological Connectome 2026-09-12 12:57:14 31
GTRACT
 
Resource Report
Resource Website
1+ mentions
GTRACT (RRID:SCR_009651) GTRACT data processing software, image analysis software, image processing software, software application, software resource, software toolkit A Diffusion Tensor fiber tracking software suite that includes streamline tracking tools. The fiber tracking includes a guided tracking tool that integrates apriori information into a streamlines algorithm. This suite of programs is built using the NA-MIC toolkit and uses the Slicer3 execution model framework to define the command line arguments. These tools can be fully integrated with Slicer3 using the module discovery capabilities of Slicer3. NOTE: All new development is being managed in a github repository. Please visit, https://github.com/BRAINSia/BRAINSTools c++, dicom, macos, microsoft, modeling, morphology, magnetic resonance, nifti, posix/unix-like, quantification, tensor metric, tractography, windows, dti, diffusion tensor fiber tracking, fiber tracking, nrrd, algorithm, connectivity is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: 3D Slicer
has parent organization: University of Iowa; Iowa; USA
Aging NARSAD ;
NINDS R01NS050568-01A2S1;
NINDS 5R01NS040068-04;
NIMH 5R01MH063405-04;
NIMH 5R01MH031593-23;
NIMH 2R01MH040856-17A2;
NIA 5K23AG020649-03;
NIDCR 5R01DE014399-04
PMID:16631385 BSD License nlx_155992 SCR_009651 Guided Tensor Restore Anatomical Connectivity Tractography 2026-09-12 12:57:14 2
REST: a toolkit for resting-state fMRI
 
Resource Report
Resource Website
1000+ mentions
REST: a toolkit for resting-state fMRI (RRID:SCR_009641) REST data processing software, image analysis software, image processing software, software application, software resource, software toolkit A user-friendly convenient toolkit to calculate Functional Connectivity (FC), Regional Homogeneity (ReHo), Amplitude of Low-Frequency Fluctuation (ALFF), Fractional ALFF (fALFF), Gragner causality and perform statistical analysis. You also can use REST to view your data, perform Monte Carlo simulation similar to AlphaSim in AFNI, calculate your images, regress out covariates, extract Region of Interest (ROI) time courses, reslice images, and sort DICOM files. correlation, cross-correlation, fourier time-domain analysis, gnome, kde, linux, macos, matlab, microsoft, modeling, magnetic resonance, nifti, posix/unix-like, spatial transformation, spectral analysis, statistical operation, temporal transformation, time domain analysis, two dimensional display, visualization, windows, resting-state functional magnetic resonance imaging, resting-state fmri is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Beijing Normal University; Beijing; China
National High Technology Program of China ;
National Natural Science Foundation of China ;
Program for Changjiang Scholars and Innovative Research Team in University
PMID:21949842 Academic Free License nlx_155936 http://www.nitrc.org/projects/rest SCR_009641 Resting-State fMRI Data Analysis Toolkit, REsting State fMRI Data analysis Toolkit 2026-09-12 12:57:14 1004
CANGS
 
Resource Report
Resource Website
1+ mentions
CANGS (RRID:SCR_011837) CANGS data analysis software, data processing software, software application, software resource A user-friendly utility for processing and analyzing 454 GS-FLX data in biodiversity studies. windows, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
PMID:20180949 biotools:cangs, OMICS_01084 https://bio.tools/cangs SCR_011837 2026-09-12 12:57:40 1
miRPlant
 
Resource Report
Resource Website
10+ mentions
miRPlant (RRID:SCR_012105) software resource A user-friendly plant miRNA prediction tool. applet, unix/linux, mac os x, windows, java, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:25117656 GNU General Public License OMICS_05325, biotools:mirplant https://bio.tools/mirplant SCR_012105 2026-09-12 12:57:45 14
ChiBE
 
Resource Report
Resource Website
1+ mentions
ChiBE (RRID:SCR_012110) software resource An editing and visualization software tool for pathway models represented by the BioPAX format, using SBGN Process Description Language, based on Chisio. mac os x, unix/linux, windows, java is listed by: OMICtools
has parent organization: Google Code
PMID:25086704 Free, Public OMICS_05454 SCR_012110 Chisio BioPAX Editor 2026-09-12 12:57:45 3
diCal-IBD
 
Resource Report
Resource Website
diCal-IBD (RRID:SCR_012111) software resource Software tool for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences. standalone software, unix/linux, mac os x, windows, python is listed by: OMICtools
has parent organization: SourceForge
PMID:25147361 BSD License OMICS_05459 SCR_012111 2026-09-12 12:57:45 0

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