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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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NeuronUnit Resource Report Resource Website 1+ mentions |
NeuronUnit (RRID:SCR_015634) | software resource, software toolkit, source code | Software toolkit for data-driven validation of neuron and ion channel models using SciUnit. NeuronUnit implements an interface to several simulators and model description languages, handles test calculations according to domain standards, and enables automated construction of tests based on data from several major public data repositories. | ion channel, neuron, validation, simulation, model description language, modeling software | uses: SciUnit | NIBIB R01EB021711 | Tutorial available | SCR_015634 | 2026-09-03 05:08:14 | 4 | |||||||||
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Laser Biomedical Research Center Resource Report Resource Website 1+ mentions |
Laser Biomedical Research Center (RRID:SCR_000106) | LBRC | access service resource, biomedical technology research center, service resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Biomedical technology research center that develops basic scientific understanding and new techniques required for advancing clinical applications of lasers and spectroscopy. LBRC merges optical spectroscopy, imaging, scattering, and interferometry techniques to study biophysics and biochemistry of healthy and diseased biological structures from subcellular to entire-organ scale. | spectroscopy, laser, biomedicine, optical spectroscopy, imaging, scattering, interferometry, optical probe, microscopy | has parent organization: Massachusetts Institute of Technology; Massachusetts; USA; | Pre-cancer, Cancer, Atherosclerosis, Healthy, Diseased | NIBIB 4P41EB015871-30 | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_152645 | SCR_000106 | MIT Laser Biomedical Research Center, Laser Biomedical Research Center (LBRC) | 2026-09-03 05:05:44 | 4 | |||||
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Center for EPR Imaging in Vivo Physiology Resource Report Resource Website |
Center for EPR Imaging in Vivo Physiology (RRID:SCR_001410) | Center for EPR Imaging in Vivo Physiology | biomedical technology research center, training resource | Biomedical technology research center that develops instrumentation, analysis techniques, spin probes and spin traps, and methodologies for imaging physiologically relevant aspects of tissue fluids, including high-resolution oxygen maps, with very low frequency electron paramagnetic resonance imaging (EPRI). Novel bridges and high-access, low-field magnet/gradient systems have produced physiologically relevant measurements and accommodate a number of resonant structures. The Center is a consortium between the University of Chicago, the University of Denver, the University of Maryland and Novosibirsk Institute of Organic Chemistry (NIOC), Russia. | electron paramagnetic resonance, in vivo, spin probe | has parent organization: University of Chicago; Illinois; USA | Diseased, Healthy | NIBIB 4P41EB002034-17 | nlx_152632 | SCR_001410 | Center for Electron Paramagnetic Resonance (EPR) Imaging in Vivo Physiology, Center for Electron Paramagnetic Resonance Imaging in Vivo Physiology, Very Low Frequency ERP Imaging In Vivo Physiology | 2026-09-03 05:06:03 | 0 | ||||||
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Laser Microbeam and Medical Program Resource Report Resource Website 1+ mentions |
Laser Microbeam and Medical Program (RRID:SCR_001409) | LAMMP | biomedical technology research center, training resource | Biomedical technology research center dedicated to the use of lasers and optics in biology and medicine with activities in technological research and development, collaborative research, service, training, and dissemination. One of the primary goals of LAMMP is to facilitate translational research by rapidly moving basic science and technology discoveries from blackboard to benchtop to bedside. This is accomplished by combining state of the art optical technologies with specialized resource facilities for cell and tissue engineering, histopathology, pre-clinical animal models, and clinical care. The resource center has been organized into 3 cores: * Microscopy and Microbeam Technologies (MMT) for high-resolution functional imaging and manipulation of living cells and tissues * Medical Translational Technologies (MTT) for non- and minimally-invasive monitoring, treating, and imaging pre-clinical animal models and human subjects, and * Virtual Photonics Technologies (VPT) for developing computational models and methods that advance the performance of biophotonic technologies, and enhance the information content derived from optical measurements. LAMMP cores contain complementary technologies that are capable of quantitatively characterizing, imaging, and perturbing structure and biochemical function in cells and tissues with scalable resolution and depth sensitivity ranging from micrometers to centimeters. | laser, optics, biology, medicine, imaging, microscopy, microbeam, photonics, computational model, cell, tissue | has parent organization: University of California at Irvine; California; USA | NIBIB P41EB015890 | Free, Freely Available | nlx_152631 | http://lammp.bli.uci.edu/ | SCR_001409 | 2026-09-03 05:05:41 | 4 | ||||||
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Pittsburgh NMR Center for Biomedical Research Resource Report Resource Website |
Pittsburgh NMR Center for Biomedical Research (RRID:SCR_001408) | Pittsburgh NMR Center for Biomedical Research | biomedical technology research center, training resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 19,2024. Biomedical Technology Research Center that develops methodologies for the acquisition of morphological, biochemical, cellular, and functional information in living animals using nuclear magnetic resonance imaging (MRI) and spectroscopy (MRS). Novel techniques utilizing multidimensional MR imaging, magnetic resonance microscopy (MRM), and multinuclear in vivo spectroscopy are being applied to a wide range of problems in the biomedical sciences. | mri, magnetic resonance spectroscopy, imaging, in vivo, nuclear magnetic resonance imaging, magnetic resonance microscopy, multinuclear | has parent organization: Carnegie Mellon University; Pennsylvania; USA | NIBIB P41 EB001977 | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_152651 | SCR_001408 | 2026-09-03 05:06:13 | 0 | |||||||
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Hyperpolarized MRI Technology Resource Center Resource Report Resource Website |
Hyperpolarized MRI Technology Resource Center (RRID:SCR_001405) | Hyperpolarized MRI Technology Resource Center | biomedical technology research center, training resource | Biomedical technology research center developing, investigating, and disseminating new hyperpolarized MR techniques, new 13C agents and specialized analysis open-source software for data reconstruction and interpretation. The Technology Research & Development projects will leverage the extensive DNP facilities and experience of the project leaders to develop improved, robust hyperpolarized MRI methods. These technology developments will be driven by Collaborative Projects led by outstanding clinical and basic scientists who aim to use hyperpolarized 13C MRI to accomplish the scientific goals of their funded research. These technical developments will also be disseminated to the Service Project investigators for extramural feedback and then widely to the scientific community via a dedicated website and onsite training. This center will provide state-of-the-art training in this new metabolic imaging field and sponsor a yearly symposium focused on hyperpolarized MR technology development. | mri, hyperpolarized, dynamic nuclear polarization, imaging, carbon-13 | has parent organization: University of California at San Francisco; California; USA | NIBIB P41EB013598 | Free, Freely Available | nlx_152628 | SCR_001405 | UCSF Hyperpolarized MRI Technology Resource Center | 2026-09-03 05:05:55 | 0 | ||||||
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National Center for Image-Guided Therapy Resource Report Resource Website 1+ mentions |
National Center for Image-Guided Therapy (RRID:SCR_001419) | NCIGT | biomedical technology research center, training resource | Biomedical Technology Resource Center that serves as a national resource for all aspects of research into medical procedures that are enhanced by imaging. Its common goal is to provide more effective patient care. The center is focused on the multidisciplinary development of innovative image-guided intervention technologies to enable effective, less invasive clinical treatments that are not only more economical, but also produce better results for patients. The NCIGT is helping to implement this vision by serving as a proving ground for some of the next generation of medical therapies. | clinical, patient care, imaging, medical procedure | has parent organization: Harvard Medical School; Massachusetts; USA | NIBIB P41EB015898 | Free, Freely Available | nlx_152641 | SCR_001419 | National Center for Image Guided Therapy | 2026-09-03 05:05:36 | 2 | ||||||
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Radiological Research Accelerator Facility Resource Report Resource Website 1+ mentions |
Radiological Research Accelerator Facility (RRID:SCR_001425) | RARAF | access service resource, biomedical technology research center, service resource, training resource | Biomedical technology research center dedicated for radiobiological research with available ionizing radiations such as protons, alpha particles, and neutrons. RARAF is well-established and highly user-friendly. The focus of RARAF is the development of high-throughput single-cell/single-particle microbeams, which can deliver defined amounts of ionizing radiation into individual cells with a spatial resolution of a few microns or better. The ability of a microbeam to put double strand break damage at any specific known location in a given cell has allowed new approaches to the study of damage signaling. | radiobiological, ionizing radiation, proton, alpha particle, neutron, radiation, microbeam, irradiator, accelerator, ion, x-ray, cell | has parent organization: Columbia University; New York; USA | NIBIB P41 EB002033 | Free, Freely Available | nlx_152647 | SCR_001425 | Columbia University Radiological Research Accelerator Facility | 2026-09-03 05:05:41 | 1 | ||||||
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Center for In Vivo Microscopy Resource Report Resource Website 10+ mentions |
Center for In Vivo Microscopy (RRID:SCR_001426) | CIVM | biomedical technology research center, training resource | Biomedical technology research center dedicated to the development of novel imaging methods for the basic scientist and the application of the methods to important biomedical questions. The CIVM has played a major role in the development of magnetic resonance microscopy with specialized MR imaging systems capable of imaging at more than 500,000x higher resolution than is common in the clinical domain. The CIVM was the first to demonstrate MR images using hyperpolarized 3He which has been moved from mouse to man with recent clinical trials performed at Duke in collaboration with GE. More recently the CIVM has developed the molecular imaging workbench---a system dedicated to multimodality cardiopulmonary imaging in the rodent. Their collaborators are employing these unique imaging systems in an extraordinary range of mouse and rat models of neurologic disease, cardiopulmonary disease and cancer to illuminate the underlying biology and explore new therapies. | imaging, magnetic resonance microscopy, magnetic resonance imaging, clinical, mri, ct, x-ray, ultrasound, confocal, optical, spect | has parent organization: Duke University; North Carolina; USA | Cardiopulmonary disease, Cancer, Neurological disease | NIBIB 4P41EB015897-27 | Free, Freely Available | nlx_152650 | SCR_001426 | Duke Center for In Vivo Microscopy | 2026-09-03 05:05:36 | 10 | |||||
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RESBIO Resource Report Resource Website 1+ mentions |
RESBIO (RRID:SCR_001424) | RESBIO | biomedical technology research center, training resource | Biomedical technology research center that works to develop integrated tools and technologies that advance the discovery of polymeric biomaterials for regenerative medicine, the delivery of biological agents, and the next generation of medical implants. To achieve its mission, RESBIO's research is focused on the development of combinatorial and computational approaches to biomaterials design and optimization. Within this framework, RESBIO employs and uses: * Advanced multi-photon confocal laser microscopy to explore, understand, and control the response of cells in contact with artificial surfaces * Electron microscopy techniques to study the effect of nano-scale surface morphological features on cell behavior RESBIO research emphasizes the integration of a strong synthetic effort to create new biomaterial candidates with the development of rapid screening techniques for key material and biological properties relevant to the performance of a biomaterial in a given medical application. | polymeric biomaterial, regenerative medicine, biological agent, medical implant, biomaterial, design, optimization, delivery, confocal laser microscopy, electron microscopy, cell | has parent organization: Rutgers University; New Jersey; USA | NIBIB 4P41EB001046-14 | Free, Freely Available | nlx_152646 | http://www.njbiomaterials.org/web/index.php?p=resbio | SCR_001424 | Polymeric Biomaterials Resource, Integrated Technologies for Polymeric Biomaterials | 2026-09-03 05:06:13 | 1 | |||||
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Center for Magnetic Resonance and Optical Imaging Resource Report Resource Website 1+ mentions |
Center for Magnetic Resonance and Optical Imaging (RRID:SCR_001428) | CMROI | biomedical technology research center, training resource | Biomedical technology research center dedicated to the development and application of innovative, novel magnetic resonance and optical imaging techniques. The facility's core sections provide research and computing resources for numerous user, collaborative, and training projects. The focus of this resource is on developing instrumentation, methodologies, and data analysis techniques for the quantitative assessment of functional, structural, and metabolic parameters in humans with the use of multinuclear magnetic resonance, novel spectral, perfusion, functional, and optical imaging techniques. These technological developments are driven by collaboration with scientists from within and outside University of Pennsylvania, the primary institution. Specifically, the Resource is focused on the development of quantitative, noninvasive MR and optical imaging based biomarkers for studying tissue metabolism and function, with an eye towards clinical translation through early diagnosis. The Center also provides support in the development and evaluation of new therapies in a variety of diseases. | magnetic resonance imaging, optical imaging, multinuclear magnetic resonance | has parent organization: University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA | NIBIB P41 EB015893 | Free, Freely Available | nlx_152652 | http://cmroi.med.upenn.edu/ | SCR_001428 | 2026-09-03 05:05:55 | 1 | ||||||
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Center for Magnetic Resonance Research Resource Report Resource Website 1+ mentions |
Center for Magnetic Resonance Research (RRID:SCR_003148) | CMRR | access service resource, biomedical technology research center, service resource, training resource | Biomedical technology research center that focuses on development of unique magnetic resonance (MR) imaging and spectroscopy methodologies and instrumentation for the acquisition of structural, functional, and biochemical information non-invasively in humans, and utilizing this capability to investigate organ function in health and disease. The distinctive feature of this resource is the emphasis on ultrahigh magnetic fields (7 Tesla and above), which was pioneered by this BTRC. This emphasis is based on the premise that there exists significant advantages to extracting biomedical information using ultrahigh magnetic fields, provided difficulties encountered by working at high frequencies corresponding to such high field strengths can be overcome by methodological and engineering solutions. This BTRC is home to some of the most advanced MR instrumentation in the world, complemented by human resources that provide unique expertise in imaging physics, engineering, and signal processing. No single group of scientists can successfully carry out all aspects of this type of interdisciplinary biomedical research; by bringing together these multi-disciplinary capabilities in a synergistic fashion, facilitating these interdisciplinary interactions, and providing adequate and centralized support for them under a central umbrella, this BTRC amplifies the contributions of each of these groups of scientists to basic and clinical biomedical research. Collectively, the approaches and instrumentation developed in this BTRC constitute some of the most important tools used today to study system level organ function and physiology in humans for basic and translational research, and are increasingly applied world-wide. CMRR Faculty conducts research in a variety of areas including: * High field functional brain mapping in humans; methodological developments, mechanistic studies, and neuroscience applications * Metabolism, bioenergetics, and perfusion studies of human pathological states (tumors, obesity, diabetes, hepatic encephalopathy, cystic fibrosis, and psychiatric disorders) * Cardiac bioenergetics under normal and pathological conditions * Automated magnetic field shimming methods that are critical for spectroscopy and ultrafast imaging at high magnetic fields * Development of high field magnetic resonance imaging and spectroscopy techniques for anatomic, physiologic, metabolic, and functional studies in humans and animal models * Radiofrequency (RF) pulse design based on adiabatic principles * Development of magnetic resonance hardware for high fields (e.g. RF coils, pre-amplifiers, digital receivers, phased arrays, etc.) * Development of software for data analysis and display for functional brain mapping. | mri, imaging, magnetic resonance spectroscopy, clinical, core facility, in vivo, brain mapping | has parent organization: University of Minnesota Twin Cities; Minnesota; USA | NCRR ; NIH Blueprint for Neuroscience Research ; NIBIB ; W. M. Keck Foundation |
Free, Freely available | nif-0000-00563 | SCR_003148 | NMR Imaging and Localized Spectroscopy | 2026-09-03 05:06:06 | 5 | ||||||
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3D Developmental Mouse Brain Common Coordinate Framework Resource Report Resource Website 1+ mentions |
3D Developmental Mouse Brain Common Coordinate Framework (RRID:SCR_025544) | atlas, data or information resource | Open access multimodal 3D atlases of developing mouse brain that can be used to integrate mouse brain imaging data for visualization, education, cell census mapping, and more. Atlas ages include E11.5, E13.5, E15.5, E18.5, P4, P14, and P56. Web platform can be utilized to visualize and explore the atlas in 3D. Downloadable atlas can be used to align multimodal mouse brain data. Morphologically averaged symmetric template brains serve as the basis reference space and coordinate system. Anatomical labels are manually drawn in 3D based on the prosomeric model. For additional references, the P56 template includes templates and annotations from the aligned Allen Mouse Brain Common Coordinate Framework (Allen CCFv3) and aligned Molecular Atlas of the Adult Mouse Brain. | multimodal 3D atlases, developing mouse brain, mouse brain data, |
is related to: Allen Mouse Brain Common Coordinate Framework is organization facet of: BRAIN Initiative |
NIBIB R01EB031722; NIMH R01MH116176; NIMH RF1MH12460501; NINDS R01NS108407 |
PMID:37745386 | Free, Freely available | SCR_025544 | DevCCF | 2026-09-03 05:09:54 | 2 | |||||||
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ezBIDS Resource Report Resource Website 1+ mentions |
ezBIDS (RRID:SCR_025563) | software resource, web application | Web-based BIDS conversion tool to convert neuroimaging data and associated metadata to BIDS standard. Guided standardization of neuroimaging data interoperable with major data archives and platforms. | Guided standardization, neuroimaging data, Brain Imaging Data Structure, BIDS conversion tool, convert neuroimaging data, associated metadata, interoperable, BIDS standard, | BRAIN CONNECTS ; Kavli Foundation ; NIBIB R01EB029272; NIBIB R01EB030896; NIMH R01MH133701; NINDS UM1NS132207; NSF ; Spanish Government ; Wellcome Trust |
PMID:38332144 | Free, Freely available | https://brainlife.io/ezbids/, | SCR_025563 | ez Brain Imaging Data Structure | 2026-09-03 05:09:59 | 1 | |||||||
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MRQy Resource Report Resource Website 1+ mentions |
MRQy (RRID:SCR_025779) | data analysis software, data processing software, software application, software resource | Software quality assurance and checking tool for quantitative assessment of magnetic resonance imaging and computed tomography data. Used for quality control of MR imaging data. | quantitative assessment, magnetic resonance imaging, computed tomography, imaging data, | NCI 1F31CA216935; NCI 1U01CA239055; NCI 1U01CA248226; NCI R01CA202752; NCI R01CA208236; NCI R01CA216579; NCI R01CA220581; NCI U24CA199374; NCRR 1C06RR12463; NHLBI R01HL15127701A1; NIBIB 1R43EB028736 |
PMID:33176026 | Free, Available for download, Freely available | SCR_025779 | 2026-09-03 05:10:15 | 1 | |||||||||
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HCP Pipelines Resource Report Resource Website 10+ mentions |
HCP Pipelines (RRID:SCR_026575) | data processing software, image processing software, software application, software resource, software toolkit | Software package as set of tools, primarily shell scripts, for processing multi-modal, high-quality MRI images for the Human Connectome Project. Minimal preprocessing pipelines for structural, functional, and diffusion MRI that were developed by the HCP to accomplish many low level tasks, including spatial artifact/distortion removal, surface generation, cross-modal registration, and alignment to standard space. | Minimal preprocessing pipelines, Human Connectome Project, MRI images processing, MRI images, | NCRR U24 RR021382; NIA R01AG008122; NIBIB R01EB006758; NIH Blueprint for Neuroscience Research ; NIMH F30 MH097312; NIMH MH091657; NIMH ROI MH60974; NINDS R01 NS052585; NINDS R01NS070963; NINDS R21NS072652 |
PMID:23668970 | Free, Available for download, Freely available | https://www.humanconnectome.org/software/hcp-mr-pipelines | SCR_026575 | Human Connectome Project Pipelines | 2026-09-03 05:11:03 | 36 | |||||||
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Reproducible Brain Charts Resource Report Resource Website |
Reproducible Brain Charts (RRID:SCR_027837) | data or information resource, data set | Open data resource for mapping brain development and its associations with mental health. Integrates data from 5 large studies of brain development in youth from three continents (N = 6,346). Bifactor models were used to create harmonized psychiatric phenotypes, capturing major dimensions of psychopathology. Neuroimaging data were carefully curated and processed using consistent pipelines in a reproducible manner. | Neuroimaging data, curated data, data resource, mapping brain development, mental health, | NIBIB R01EB022573; NIMH K08MH079364; NIMH P50MH109429; NIMH R01MH112847; NIMH R01MH113550; NIMH R01MH120482; NIMH R01MH123440; NIMH R01MH123550; NIMH R37MH125829; NIMH RF1MH121867; NINDS U24NS130411 |
PMID:40987284 | Free, Freely available | SCR_027837 | 2026-09-03 05:11:58 | 0 | |||||||||
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Spectroscopic Imaging, VIsualization, and Computing (SIVIC) Resource Report Resource Website 1+ mentions |
Spectroscopic Imaging, VIsualization, and Computing (SIVIC) (RRID:SCR_027875) | SIVIC | software application, software resource | Software framework and application suite for processing and visualization of DICOM MR Spectroscopy data. Through the use of DICOM, SIVIC aims to facilitate the application of MRS in medical imaging studies. | DICOM MR Spectroscopy Workflows, data processing, data visualization, DICOM MR spectroscopy data, | NCI P01 CA11816; NCI RO1 CA127612; NIBIB P41EB013598 |
PMID:23970895 | Free, Available for download, Freely available | SCR_027875 | 2026-09-03 05:12:20 | 2 | ||||||||
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NITRC-IR Resource Report Resource Website 1+ mentions |
NITRC-IR (RRID:SCR_004162) | NITRC IR | catalog, data or information resource, data repository, database, image database, image repository, service resource, storage service resource | Data repository for neuroimaging data in DlCOM and NIFTI formats. It allows users to search for and freely download publicly available data sets relating to normal subjects and those with diagnoses such as: schizophrenia, ADHD, autism, and Parkinson's disease.XNAT-based image registry that supports both NIfTI and DICOM images to promote re-use and integration of NIH funded data. | database, neuroimaging, magnetic resonance, mri, image collection, nifti, dicom |
uses: XNAT Central is used by: NIF Data Federation lists: 1000 Functional Connectomes Project lists: studyforrest.org is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) is related to: 1000 Functional Connectomes Project is related to: NITRC Enhanced Services has parent organization: NeuroImaging Tools and Resources Collaboratory (NITRC) |
Bipolar Disorder, Schizophrenia, Parkinson's disease, ADHD | NIBIB U24 EB023398; NINDS R44 NS074540 |
PMID:26044860 | Free, Available for download, Freely available | nlx_18447, SCR_015623 | SCR_004162 | NeuroImaging Tools and Resources Collaboratory Image Repository, NITRC Image Repository | 2026-09-03 04:47:02 | 8 | ||||
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MGED Ontology Resource Report Resource Website 1+ mentions |
MGED Ontology (RRID:SCR_004484) | MO | controlled vocabulary, data or information resource, ontology | An ontology including concepts, definitions, terms, and resources for a standardized description of a microarray experiment in support of MAGE v.1. The MGED ontology is divided into the MGED Core ontology which is intended to be stable and in synch with MAGE v.1; and the MGED Extended ontology which adds further associations and classes not found in MAGE v.1. These terms will enable structure queries of elements of the experiments. Furthermore, the terms will also enable unambiguous descriptions of how the experiment was performed. | microarray, biomaterial, treatment, mage, owl |
is listed by: BioPortal is related to: MIAME is related to: MIAME is related to: RNA Abundance Database has parent organization: Functional Genomics Data Society has parent organization: SourceForge |
NIBIB ; NHGRI P41HG003619 |
PMID:16428806 | nlx_47223 | http://purl.bioontology.org/ontology/MO | SCR_004484 | Microarray and Gene Expression Data Ontology | 2026-09-03 04:47:09 | 1 |
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