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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Institute whose mission is to understand the molecular mechanisms that underlie the aging process and that lead to age-related diseases. They hope that eventually this knowledge can contribute to a more healthy aging of people. The central question they are aiming at answering is, What are the molecular mechanisms and genetic factors contributing to the evolution of cellular and organismal dysfunction during human aging?
Proper citation: Leibniz Institute for Age Research (RRID:SCR_011340) Copy
http://www.ipk-gatersleben.de/en/
Proper citation: Leibniz Institute of Plant Genetics and Crop Plant Research; Saxony-Anhalt; Germany (RRID:SCR_011341) Copy
Public research university in Leiden, Netherlands. Founded in 1575 by William, Prince of Orange as a reward to the town of Leiden for its defense against Spanish attacks during the Eighty Years' War, it is the oldest institution of higher education in the Netherlands.
Proper citation: Leiden University; Leiden; Netherlands (RRID:SCR_011342) Copy
The Library of Congress is the nation''s oldest federal cultural institution and serves as the research arm of Congress. It is also the largest library in the world, with millions of books, recordings, photographs, maps and manuscripts in its collections. The Library''s mission is to support the Congress in fulfilling its constitutional duties and to further the progress of knowledge and creativity for the benefit of the American people. Thousands of dedicated staff acquire, catalog, preserve, and make available library collections within our three buildings on Capitol Hill and over the Internet.
Proper citation: Library of Congress (RRID:SCR_011343) Copy
Institution dedicated to research and teaching in the field of tropical medicine. As a registered charity, they work in over 60 countries worldwide, often in very difficult circumstances, to fulfill their mission of reducing the burden of sickness and mortality in disease endemic countries through the delivery of effective interventions which improve human health and are relevant to the poorest communities. Their new Centre for Tropical and Infectious Diseases is a state of the art facility for developing new drugs, vaccines and pesticides which puts us at the forefront of infectious disease research. As a teaching institution, they attract more than 600 students from 68 countries, from PhD research and Masters programs to a range of short courses, and work in partnership with health ministries, universities and research institutions worldwide to train the next generation of doctors, scientists, researchers and health professionals. The provision of technical assistance is a major component of LSTM''s mission of promoting the improved health of the poor and disadvantaged peoples. LSTM consultancy improves health systems in developing countries whilst helping to inform their teaching and research agendas.
Proper citation: Liverpool School of Tropical Medicine; Liverpool; United Kingdom (RRID:SCR_011345) Copy
Los Alamos National Laboratory is a premier national security research institution, delivering scientific and engineering solutions for the nation''s most crucial and complex problems. Our primary responsibility is ensuring the safety, security, and reliability of the nation''s nuclear deterrent. The Los Alamos of today emphasizes worker safety, effective operational safeguards & security, and environmental stewardship, while outstanding science remains the foundation of the Laboratory. In addition to supporting the Lab''s core national security mission, our work advances bioscience, chemistry, computer science, earth and environmental sciences, materials science, and physics disciplines.
Proper citation: Los Alamos National Laboratory (RRID:SCR_011349) Copy
Officially Louisiana State University and Agricultural and Mechanical College, commonly referred to as LSU is a public land-grant research university in Baton Rouge, Louisiana.The university was founded in 1853 in what is now known as Pineville, Louisiana, under the name Louisiana State Seminary of Learning and Military Academy.
Proper citation: Louisiana State University; Louisiana; USA (RRID:SCR_011351) Copy
A public research university in France that emphasizes medical and scientific research centered on four themes: life and health, the living earth and environment, matter and new materials and modeling and engineering. It is a member of the Sorbonne Universities alliance.
Proper citation: Sorbonne University; Paris; France (RRID:SCR_000246) Copy
http://saweb2.sabiosciences.com/manuals/GEArrayBrochure.pdf
THIS RESOURCE HAS BEEN DISCONTINUED, documented April 15, 2016. New GEArray Expression Analysis Suite 2.0 was released at Dec 21, 2006, please read Release Notices for details. SABiosciences' GEArray Analysis Suite uses advanced Java functionality. In order to experience full functionality of this Portal, the following free programs and upgrades for PC and Macs should be properly installed. PC Environment Downloads Browser compatibility is not an issue on Windows systems, so all operating systems running Windows 98 and above and either Internet explorer or Netscape should be fine. Java 1.4.1 or above is required--this should download automatically upon the first entry into the Portal. If this does not happen, Java 1.5 is available for download from the following URL: Java 1.5 Mac Environment Downloads Browser compatibility is an issue, and Mac Operating Systems prior to Panther are not able to fully take advantage of this Portal's functionality. These programs need to be downloaded and installed in a specific order as follows: Panther 10.3.5 (Operating System), Safari 1.2 (Compatible Internet Browser) and Java 1.4.2 (Java environment). Abstract. INTRODUCTION: Toll-like receptors (TLR) comprehend an emerging family of receptors that recognize pathogen-associated molecular patterns and promote the activation of leukocytes. Surgical trauma and ischemia-reperfusion injury are likely to provide exposure to endogenous ligands for TLR in virtually all kidney transplant recipients. METHODS: Macroarray (GEArray OHS-018.2 Series-Superarray) analyses of 128 genes involved in TLR signaling pathway were performed in nephrectomy samples of patients with chronic allograft nephropathy (CAN) and acute rejection (AR, vascular and non vascular). The analysis of each membrane was performed by GEArray Expression Analysis Suite 2.0. RESULTS: Macroarray profile identified a gene expression signature that could discriminate CAN and AR. Three genes were significantly expressed between CAN and vascular AR: Pellino 2; IL 8 and UBE2V1. In relation to vascular and non-vascular AR, there were only two genes with statistical significance: IL-6 and IRAK-3. CONCLUSION: Vascular and non-vascular AR and CAN showed different expression of a few genes in TLR pathway. The analysis of nephrectomy showed that activation of TLR pathway is present in AR and CAN. Sponsor. This work was supported by the inconditional grant from Fundao de Amparo a Pesquisa do Estado de So Paulo (FAPESP, 04/08311-6), from Conselho Nacional de Pesquisa e Desenvolvimento (CNPq) and from Fundao Osvaldo Ramos.
Proper citation: GEArray Expression Analysis Suite 2.0 (RRID:SCR_000282) Copy
http://sourceforge.net/projects/blastplot/
A PERL module that can quickly plot the BLAST results from short sequences (primers, probes, reads) against reference targets. This software generates PNG graphs for all of the reference sequences associated with a BLAST result set.
Proper citation: BLASTPLOT (RRID:SCR_000162) Copy
http://sourceforge.net/projects/gemsim/
A software package for generating realistic simulated next-generation genome sequencing reads with quality score values. The software is written in Python with a command-line user interface.
Proper citation: GemSIM (RRID:SCR_000167) Copy
http://sourceforge.net/projects/gmato/files/?source=navbar
A software tool used for simple sequence repeats (SSR) or microsatellite characterization. It also facilitates SSR marker design on a genomic scale, microsatellite mining at any length, and comprehensive statistical analysis for DNA sequences in any genome at any size. Analysis parameters are customizable.
Proper citation: GMATo (RRID:SCR_000165) Copy
http://proteinprophet.sourceforge.net/
Software that automatically validates protein identifications made on the basis of peptides assigned to MS/MS spectra by database search programs such as SEQUEST.
Proper citation: ProteinProphet (RRID:SCR_000286) Copy
A public pharmacy school, part of the University of Illinois. It offers a four-year professional degree program that leads to the PharmD, the highest level of professional education in pharmacy. The college also offers programs leading to six master's degrees and four doctorate degrees, covering a spectrum of research areas within the pharmaceutical sciences.
Proper citation: University of Illinois College of Pharmacy (RRID:SCR_000280) Copy
http://www.incf.org/resources/data-space/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented August 21, 2017.
Repository for sharing of neuroscience data, text, images, sounds, movies, models and simulations.
Proper citation: INCF Dataspace (RRID:SCR_000158) Copy
https://www.uni-stuttgart.de/en/
A public research university with 10 programs in disciplines of science, social science and humanities. The institution has technical programs in civil, mechanical, industrial and electrical engineering.
Proper citation: University of Stuttgart; Stuttgart; Germany (RRID:SCR_000153) Copy
http://cran.r-project.org/src/contrib/Archive/iFad/
An R software package implementing a bayesian sparse factor model for the joint analysis of paired datasets, the gene expression and drug sensitivity profiles, measured across the same panel of samples, e.g. cell lines.
Proper citation: iFad (RRID:SCR_000271) Copy
http://bioinfo.unl.edu/gramcluster.php
Software implementing a fast and accurate progressive clustering algorithm that relies on a grammar-based sequence distance and is particularly useful in clustering large datasets.
Proper citation: GramCluster (RRID:SCR_000272) Copy
http://cran.r-project.org/src/contrib/Archive/postgwas/
A comprehensive software toolkit for post-processing, visualization and advanced analysis of GWAS results.
Proper citation: Postgwas (RRID:SCR_000156) Copy
Public university in Ontario, Canada that offers degree programs in the social sciences and engineering at both the undergraduate, graduate, postdoctorate and professional level. The university operates six research centers that focus on disciplines such as neuroscience, computing, human mobility and Southern African research.
Proper citation: Queens University; Ontario; Canada (RRID:SCR_000278) Copy
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