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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://snpeff.sourceforge.net/
Genetic variant annotation and effect prediction software toolbox that annotates and predicts effects of variants on genes (such as amino acid changes). By using standards, such as VCF, SnpEff makes it easy to integrate with other programs.
Proper citation: SnpEff (RRID:SCR_005191) Copy
http://www.cs.helsinki.fi/u/lmsalmel/mip-scaffolder/
A software program for scaffolding contigs produced by fragment assemblers using mate pair data such as those generated by ABI SOLiD or Illumina Genome Analyzer.
Proper citation: MIP Scaffolder (RRID:SCR_005072) Copy
http://compbio.cs.toronto.edu/hapsembler/scarpa.html
A stand-alone scaffolding tool for NGS data. It can be used together with virtually any genome assembler and any NGS read mapper that supports SAM format. Other features include support for multiple libraries and an option to estimate insert size distributions from data.
Proper citation: Scarpa (RRID:SCR_005073) Copy
A web server designed to rapidly and accurately identify, annotate and graphically display prophage sequences within bacterial genomes or plasmids. It accepts either raw DNA sequence data or partially annotated GenBank formatted data and rapidly performs a number of database comparisons as well as phage cornerstone feature identification steps to locate, annotate and display prophage sequences and prophage features. Relative to other prophage identification tools, PHAST is up to 40 times faster and up to 15% more sensitive. It is also able to process and annotate both raw DNA sequence data and Genbank files, provide richly annotated tables on prophage features and prophage quality and distinguish between intact and incomplete prophage. PHAST also generates downloadable, high quality, interactive graphics that display all identified prophage components in both circular and linear genomic views. Databases available for download include Virus DB, Prophage and virus DB, Bacteria DB, and PHAST result DB. Pre-calculated genomes for viewing are also available.
Proper citation: PHAge Search Tool (RRID:SCR_005184) Copy
http://www.bmbf.de/en/index.php
Proper citation: German Federal Ministry of Education and Research (RRID:SCR_005066) Copy
http://code.google.com/p/snpdat/
A simple and easy to use high through-put analysis tool which can provide comprehensive annotation of both novel and known single nucleotide polymorphisms (SNPs) for any organism with a draft sequence and annotation. SNPdat makes possible analyses involving non-model organisms that are not supported by the vast majority of SNP annotation tools currently available. It is especially intended for use by researchers with limited bioinformatic experience.
Proper citation: SNPdat (RRID:SCR_005187) Copy
http://brainethics.org/?page_id=849
How do the recent developments in neuroscience affect psychology and society? Today, many new findings challenge the way we think about ourselves and others. These changes impact on how we should think about issues such as the self, mentality, psychology, free will, morale, law and society. Through interviews of prominent scholars in the fields of neuroscience and beyond, the BrainEthics Podcast provides updated, novel and comprehensive news and views from the world of neuroscience, and how the world responds to it. We provide a full list of all podcast episodes. Although we are hosting all episodes, you can also subscribe to the podcast on all major podcasting directories.
Proper citation: BrainEthics Podcast (RRID:SCR_005533) Copy
https://github.com/SciCrunch/NIF-Ontology
The NIF Standard Ontology (NIFSTD) is a collection of modular ontologies that provides an extensive set of terms and concepts important for the domains of neuroscience and biology, as well as the data and resources relevant for the life sciences. It is a core component of the Neuroscience Information Framework (NIF) project, a semantically enhanced portal for accessing and integrating neuroscience data, tools and information.
Proper citation: NIFSTD (RRID:SCR_005414) Copy
Public research university in Lisbon, and the largest university in Portugal. It was founded in 2013, from the merger of two previous public universities located in Lisbon, the former University of Lisbon and the Technical University of Lisbon.
Proper citation: University of Lisbon; Lisbon; Portugal (RRID:SCR_005415) Copy
http://ccb.jhu.edu/software/FLASH/
Open source software tool to merge paired-end reads from next-generation sequencing experiments. Designed to merge pairs of reads when original DNA fragments are shorter than twice length of reads. Can improve genome assemblies and transcriptome assembly by merging RNA-seq data.
Proper citation: FLASH (RRID:SCR_005531) Copy
http://www.iarc.fr/en/publications/pdfs-online/wrk/wrk2/index.php
The IARC Working Group Reports contain common minimum technical standards and protocols for Biological Resource Centres dedicated to Cancer Research. * Cover Page * Table of Contents * Working group participants * Preamble * Definitions * Roles of biological resource centres in cancer research * Recommendations for BRCs * Selected protocols * Annexes
Proper citation: IARC Recommendations and Protocols for Biobanking (RRID:SCR_005408) Copy
http://mlab.cb.k.u-tokyo.ac.jp/~quwei/DeNovoShortReadClustering/
An algorithm for efficient frequency-based de novo short read clustering for error trimming in next-generation sequencing. It organizes erroneous short sequences originating in a single abundant sequence into a tree structure such that each child sequence is considered to be derived stochastically from its more abundant parent sequence because of sequencing errors.
Proper citation: FreClu (RRID:SCR_005524) Copy
The OECI is a non-government, non-profit organization founded in Vienna in 1979. The primary objectives of its 68 associated European Cancer Centres are to improve communication and to increase collaborative activities among European cancer institutes. These goals are achieved by promoting and strengthening Comprehensive Cancer Centres in Europe to reduce cancer incidence and mortality, and supporting cancer patients. The OECI leadership has demonstrated its active involvement in the promotion of a European approach to cancer management as a partner with UICC in the series of European Cancer Management Meetings organized with support from the European Union (Antwerp, 2000; Paris 2001). OECI members are leading Cancer Centres throughout Europe, encompassing the full spectrum of Cancer activities and national considerations. In order to facilitate the activities of their members and the definition of common programs of international interest and to facilitate the participation in European projects and programs the GEIE-LINC and the OECI in 2001 decided to set-up 9 specific Working Groups active in the following fields: Guidelines, Registration & Data Evaluation, Cost-Benefit, Pre-Clinical and Clinical Research, Education, Communication, Telematics & Telemedicine, Pathology, New Technologies
Proper citation: OECI - Organisation for European Cancer Institutes (RRID:SCR_005521) Copy
Network that brings together researchers in imaging genomics, to understand brain structure and function, based on MRI, DTI, fMRI and genomewide association scan (GWAS) data. The ENIGMA Network has several goals: * to create a network of like-minded individuals, interested in pushing forward the field of imaging genetics * to ensure promising findings are replicated via member collaborations, in order to satisfy the mandates of most journals * to share ideas, algorithms, data, and information on promising findings or methods * to facilitate training, including workshops and conferences on key methods and emerging directions in imaging genetics. Data sharing with other members of the ENIGMA Network is optional and by no means a requirement of joining the network. Genetics and Imaging Protocols are available.
Proper citation: ENIGMA: Enhancing Neuro Imaging Genetics Through Meta-Analysis (RRID:SCR_005515) Copy
http://www.diplomatie.gouv.fr/en/
The Ministry of Foreign Affairs and is the ministry in the government of France that handles France's foreign relations.
Proper citation: French Ministry of Foreign Affairs and International Development (RRID:SCR_005518) Copy
http://www.ebi.ac.uk/Rebholz-srv/ebimed/
A web application that combines Information Retrieval and Extraction from Medline. EBIMed finds Medline abstracts in the same way PubMed does. Then it goes a step beyond and analyses them to offer a complete overview on associations between UniProt protein/gene names, GO annotations, Drugs and Species. The results are shown in a table that displays all the associations and links to the sentences that support them and to the original abstracts. By selecting relevant sentences and highlighting the biomedical terminology EBIMed enhances your ability to acquire knowledge, relate facts, discover implications and, overall, have a good overview economizing the effort in reading.
Proper citation: EBIMed (RRID:SCR_005314) Copy
Non profit bioscience research organization in Seattle, Washington dedicated to accelerating research globally and sharing that data within the science community. Allen Institute for Brain Science, Allen Institute for Cell Science, Allen Institute for Immunology, and The Paul G. Allen Frontiers Group are four divisions of this Institute with commitment to open science model within its research institutes.
Proper citation: Allen Institute (RRID:SCR_005435) Copy
http://www.ncats.nih.gov/research/reengineering/ncgc/ncgc.html
The NIH Chemical Genomics Center (NCGC) was created in 2008 as a Comprehensive Screening Center in the Molecular Libraries Probe Production Centers Network, part of the NIH Molecular Libraries Common Fund Program. The goals of NCGC in the NCATS Division of Pre-Clinical Innovation are to translate the discoveries of the Human Genome Project into biological and disease insights and ultimately new therapeutics for human disease through small molecule assay development, high-throughput screening, cheminformatics and chemistry. NCGC programs include Assay Development and High-Throughput Screening, Chemistry Technology and RNAi. In addition, NCGC is one of 12 centers that make up the National Cancer Institute''s Chemical Biology Consortium. These centers use the consortium''s high-throughput screening, informatics and chemistry resources to work on select cancer biology projects and move them through the therapeutics development pipeline, eventually into the clinic. Through such programs, NCGC produces a variety of pre-clinical research tools, from informatics and software tools to an assay guidance manual and more than 200 molecular probes.
Proper citation: NIH Chemical Genomics Center (RRID:SCR_005557) Copy
Starlab''s mission is to transform science into technologies with a profound and positive impact on society. We achieve this by identifying social needs and the market opportunities they create. Then we reach to science and engineering to propose or provide technical solutions, products and services for governments, industry and downstream markets. Starlab Research carries out interdisciplinary R&D focusing on two areas: Space and Applied Neuroscience. Our vision is to make science more useful, alive, vibrant, faster. Our staff consists of a team of scientists, engineers and economists from different nationalities working together to provide our clients with breakthrough technologies that create business opportunities. The growing Starlab team (now more than 28 on staff) includes 5 nationalities spanning knowledge in physics, engineering, oceanography, computer science, neuroscience and economics. Circa 50% of our staff have a PhD, and more than 80% a Master or PhD. We target technology and applications: the development of new sensors and efficient algorithms to extract information from data, identification of platforms and deployment opportunities, as well as the development of services and products. Interdisciplinarity is a key aspect of our research. Space R&D develops payloads, algorithms and mission feasibility studies. We have demonstrated experience in GNSS technologies, radar altimetry and space astronomy. Earth Observation applications include technologies such as GNSS-R, SAR and multi-spectral analysis for environmental and energy applications. We have demonstrated expertise in the development of innovative sensors and systems in both the Space and Applied Neuroscience areas, signal-processing algorithms, with a strong specialization in electrophysiology algorithms, software and hardware. It will also manage the project and prospect potential commercial impact.
Proper citation: Starlab (RRID:SCR_005551) Copy
http://www.colorado.edu/neuroscienceprogram/
The University of Colorado at Boulder offers a Ph.D. in Neuroscience, as well as graduate and undergraduate Certificates in Neuroscience that can be combined with a variety of majors. The Neuroscience Community at the University of Colorado at Boulder is made up of over 80 faculty and research associates rostered in 13 departments and institutes. Neuroscience activities on the campus are coordinated by the Center for Neuroscience.
Proper citation: University of Colorado at Boulder, Department of Neuroscience (RRID:SCR_005310) Copy
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