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https://med.uc.edu/research/core/Index/208/Facility/

Integrates technology in single-particle cryogenic electron microscopy. Thermo Scientific Talos L120C Transmission Electron Microscope is available for visualizing nanoparticles, negatively stained proteins or conventional biological samples. It can be operated at 80kV or 120kV. Thermo Scientific Glacios 200 kV cryogenic TEM is equipped with both Ceta-16M camera and TFS Falcon 4 direct electron detector, in addition to Selectris Energy Filter. This system is able to generate images for atomic resolution structures for single particle analysis projects. Glacios also includes software for micro-Electron Diffraction data set collection. Available services include Training and access to the Mark IV Vitrobot plunge freezer,Training and access to the Talos L120C TEM system, Training and access to the Glacios 200 kV cryogenic TEM system, Assisted TEM analysis by CASB personnel.

Proper citation: University of Cincinnati Center for Advanced Structural Biology Core Facility (RRID:SCR_025796) Copy   

•   Source: SciCrunch Registry

https://med.uc.edu/research/core/Index/36/Facility/

Offers access to microscopes and flow cytometry equipment for researchers. Available services include Upright and inverted widefield microscopy, Confocal Microscopy (Zeiss LSM 710), Super-Resolution Microscopy (Nikon SIMe), Live Cell Microscopy (Incucylte), Flow Cytometry (BD LSR Fortessa), Cell Sorting (BD Aria III).

Proper citation: University of Cincinnati Advanced Cell Analysis Service Center Core Facility (RRID:SCR_025797) Copy   

•   Source: SciCrunch Registry

https://mct.stanford.edu/

Core provides nondestructive, high-resolution images of internal structure of variety of natural and engineered materials using X-ray micro-computed tomography. microCT can resolve structures on micrometer scale.

Proper citation: Stanford University MicroCT Core Facility (RRID:SCR_025800) Copy   

•   Source: SciCrunch Registry

https://minpetlab.stanford.edu/

Core offers qualitative and quantitative characterization of Earth materials by providing optical microscopes for high-resolution imaging of loose materials and thin sections, computational resources for image processing, and bench space for light processing of samples before or after use of the Sample Preparation Lab.

Proper citation: Stanford University Mineralogy and Petrology Lab Core Facility (RRID:SCR_025801) Copy   

•   Source: SciCrunch Registry

https://www.cryo-em.uni-freiburg.de/

Core offers services related to cryo electron microscopy. Services include grid preparation, screening and data collection, as well as user training.

Proper citation: University of Freiburg Cryo-Electron Microscopy Core Facility (RRID:SCR_025860) Copy   

•   Source: SciCrunch Registry

https://behavior.hms.harvard.edu/

Core offers mouse behavioral equipment and assays to test motor, cognitive, and affective behaviors. Trained users have access to behavioral testing rooms and procedure room. MBC staff offers consultation, training, and guidance in execution and interpretation of assays.

Proper citation: Harvard Medical School Mouse Behavior Core Facility (RRID:SCR_025842) Copy   

•   Source: SciCrunch Registry

https://www.pedsresearch.org/research/cores/biostatistics-core/overview/

Offers statistical expertise and services. Provides assistance and collaboration in study design, grant applications, protocol development, data analysis, publication preparation, and statistical education.

Proper citation: Emory University Pediatric Biostatistics Core Facility (RRID:SCR_025834) Copy   

•   Source: SciCrunch Registry

https://www.pedsresearch.org/research/cores/animal-physiology-core/overview/

Centralized core specializing in survival surgery, technical procedures, and ultrasound imaging for rats and mice and assistance for surgical procedures in other species.

Proper citation: Emory University Animal Physiology Core Facility (RRID:SCR_025835) Copy   

•   Source: SciCrunch Registry

https://omrf.org/research-faculty/core-facilities/clinical-genomics-center/

Offers high-throughput sequencing and genotyping services utilizing cutting edge Illumina and Xoford Nanopore systems. Sequencing facility in Oklahoma. Equipped with an Illumina NovaSeq 6000, Illumina NextSeq 2000, Illumina MiSeq, Illumina iSeq, Oxford Nanopore PromethION 2, and Oxford Nanopore MinION,Illumina iScan and Autoloader for extremely-high throughput genotyping projects. Core can perform all aspects of NGS, ranging from whole genome sequencing to single-cell transcriptomics.

Proper citation: Oklahoma Medical Research Foundation OMRF Clinical Genomics Center Core Facility (RRID:SCR_025894) Copy   

•   Source: SciCrunch Registry

https://med.uc.edu/research/core/Index/44/Facility/

Core is equipped with protein separation and mass spectrometry equipment as well as trained personnel to perform comparative analyses of complex protein mixtures and to identify differentially-expressed proteins. Offers guidance and consultation.

Proper citation: University of Cincinnati Proteomics Laboratory Core Facility (RRID:SCR_025895) Copy   

•   Source: SciCrunch Registry

https://johnshopkins.ilab.agilent.com/service_center/show_external/3819?name=reference-histology

Provides histology services for Autopsy, Cytology, Renal Pathology and Medical Archives Office within Department of Pathology. In conjunction with Pathology Send Out and Archives divisions, provides histology for clinical trial requests, scientific study or interest involving pathology materials. Services include: Complete routine paraffin histology services, including processing and sectioning; Special stains, including but not limited to carbohydrates, connective tissue, fats, lipids, microorganisms, nuclear elements, pigments, silver techniques; Immunopathology slide preparation techniques;DNA slide preparations; Frozen tissue sections; Oversized tissue processing and sectioning ;Histopathology teaching sets; Customized procedures.Services are provided for both human and animal tissue samples.

Proper citation: Johns Hopkins Reference Histology Core Facility (RRID:SCR_025986) Copy   

•   Source: SciCrunch Registry

https://www.petermac.org/research/research-technologies/bioinformatics

Provides services for data analysis, pipeline management, and artificial intelligence research and operations. Data types analysed by the core include whole-genome and whole-exome sequencing, targeted re-sequencing, radiological images, RNA-sequencing, single-cell RNA sequencing, ChIP-sequencing, NanoString and various types of microarray data. Core also develops and maintains software infrastructure required for bioinformatics processing, including pipelines and cloud provision systems.

Proper citation: Peter MacCallum Cancer Centre Bioinformatics Core Facility (RRID:SCR_025901) Copy   

•   Source: SciCrunch Registry

https://med.uth.edu/ibp/cam/

Microscopy facility serving Texas Medical Center. Facilitates utilization of advanced light microscopy techniques and quantitative image analysis to advance research programs of McGovern Medical School, UTHealth, and the greater Texas Medical Center. Fluorescence microscopy and image analysis core.

Proper citation: UTHealth Houston Center for Advanced Microscopy Core Facility (RRID:SCR_025962) Copy   

•   Source: SciCrunch Registry

https://geiselmed.dartmouth.edu/msp/

Core offers quantitative and qualitative proteomics services using LC-MS/MS technologies. Servies include sample preparation from harvested cell pellets, elutions post-enrichment or purification, or gel bands through data acquisition, quantification, and statistical analysis.

Proper citation: Dartmouth Geisel School of Medicine Biological Mass Spectrometry and Proteomics Shared Resource Core Facility (RRID:SCR_026076) Copy   

•   Source: SciCrunch Registry

https://www.goodmancancer.ca/en/histology-innovation-platform

Core provides expertise, cutting edge technology, and efficient workflows in histological processing, analysis and interpretation.

Proper citation: McGill University Goodman Cancer Institute Histology Innovation Platform Core Facility (RRID:SCR_026126) Copy   

•   Source: SciCrunch Registry

https://research.vcu.edu/cores/structural-biology/cryo-em/

Facility offers sample preparation, visualization and analysis for high resolution 3D reconstruction of frozen-hydrated proteins and macromolecular complexes. Facility is endowed with Thermofisher Scientific Tundra cryo-electron microscope, Vitrobot Mark IV cryo-plunger, Pelco easyGlow glow discharge unit, Denton DV 502B evaporator, and linux server dedicated to image processing.

Proper citation: Virginia Commonwealth University Cryo-Electron Microscopy Core Facility (RRID:SCR_027178) Copy   

•   Source: SciCrunch Registry

https://czt.amu.edu.pl/cytomika-i-analiza-komorkowa/

Core is utilized in medical biotechnology and in research focused on mammalian cells. Offers analyzing of impact of new drugs and pharmaceuticals on individual cells in vitro. Provides sorting of cell populations with desired characteristics, including fluorescent dye-stained cell sorting (FACS) analysis of cell populations for presence of specific factors, e.g. introduced fluorescent protein, surface markers, DNA content determining the size, granulation and shape of animal and other cells.

Proper citation: Adam Mickiewicz University Cytometry Laboratory Core Facility (RRID:SCR_027177) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/cancer/research/shared-resources/biorepository/

Core provides collection, annotation, and storage solutions. This Biorepository is also home to a state-wide resource, the Biorepository Alliance of Georgia for Oncology (BRAG-Onc), which functions to collect samples from 6 participating sites across the State to represent the diversity of cancer patients within the State and to enhance cancer research in Georgia.Tissue specimens are fast-frozen in vapor phase liquid nitrogen to preserve their integrity and stored in large cryofreezers at -170 to -190°C. Blood is routinely separated into serum or plasma and buffy coats prior to freezing. Blood derivatives are stored at -70 to -80°C. The freezers are monitored constantly and are connected to an alarm system to ensure that the low temperatures are maintained.

Proper citation: Augusta University Georgia Cancer Center Biorepository Core Facility (RRID:SCR_027271) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/research/core/human-physiology.php

Core provides services including body/bone composition, comprehensive assessments of cardiovascular health (conduit vessel, microvascular, and central arterial stiffness), comprehensive assessment of lung health (spirometry, diffusion, lung clearance index, exhaled NO), and metabolic/exercise testing. Expanded core services in humans include oral glucose tolerance testing and continuous glucose monitoring, 24h ambulatory blood pressure monitoring, and assessments of autonomic nervous system, cognitive function, mitochondrial function, intramuscular fat, and electrocardiograms.

Proper citation: Augusta University Human Physiology Core Facility (RRID:SCR_027270) Copy   

•   Source: SciCrunch Registry

https://www.iqm.unicamp.br/institucional/infraestrutura/cemuiq/lirmn

Institutional laboratory of Nuclear Magnetic Resonance (NMR) of the Institute of Chemistry of UNICAMP.The Institutional Nuclear Magnetic Resonance Laboratory has 6 NMR spectrometers, two for solids and four for solution probes, with the possibility of analyzing different nuclei.

Proper citation: State University of Campinas Institute of Chemistry Nuclear Magnetic Resonance Laboratory LIRMN-IQ Core Facility (RRID:SCR_027247) Copy   

•   Source: SciCrunch Registry