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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://andestools.sourceforge.net/
Software library and a suite of applications, written in Perl and R, for deep sequencing statistical analyses.
Proper citation: ANDES (RRID:SCR_002791) Copy
http://www.ncbi.nlm.nih.gov/gap
Database developed to archive and distribute clinical data and results from studies that have investigated interaction of genotype and phenotype in humans. Database to archive and distribute results of studies including genome-wide association studies, medical sequencing, molecular diagnostic assays, and association between genotype and non-clinical traits.
Proper citation: NCBI database of Genotypes and Phenotypes (dbGap) (RRID:SCR_002709) Copy
http://www.bioconductor.org/packages/release/bioc/html/pathview.html
A tool set for pathway-based data integration and visualization. It maps and renders a wide variety of biological data on relevant pathway graphs. All users need is to supply their data and specify the target pathway. Pathview automatically downloads the pathway graph data, parses the data file, maps user data to the pathway, and render pathway graph with the mapped data. In addition, Pathview also seamlessly integrates with pathway and gene set (enrichment) analysis tools for large-scale and fully automated analysis.
Proper citation: Pathview (RRID:SCR_002732) Copy
http://sourceforge.net/projects/glprobs/
Software implementing a simple and effective approach to improve the accuracy of multiple sequence alignment.
Proper citation: GLProbs (RRID:SCR_002739) Copy
http://cbb.sjtu.edu.cn/~ccwei/pub/software/CTF/CTF.php
Conditional random field (CRF) based transcription factor binding site (TFBS) finding system. The underlying CRF model can integrate features of different sources.
Proper citation: CTF (RRID:SCR_002692) Copy
http://pfind.ict.ac.cn/se/plink/
Software dedicated for the analysis of chemically cross-linked proteins or protein complexes using mass spectrometry., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: pFind Studio: pLink (RRID:SCR_000084) Copy
http://www.tm4.org/spotfinder.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software designed for the rapid, reproducible and computer-aided analysis of microarray images and the quantification of gene expression.
Proper citation: Spotfinder (RRID:SCR_000085) Copy
http://www.computationalbioenergy.org/parallel-meta.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Open source pipeline for metagenomic data analysis, which enables efficient and parallel analysis of multiple metagenomic datasets and visualization of results for multiple samples. Can perform rapid data mining among microbial community data for comparative taxonomic and functional analysis.
Proper citation: Parallel-META (RRID:SCR_000121) Copy
http://biolemmatizer.sourceforge.net/
A domain-specific lemmatization software tool for the morphological analysis of biomedical literature.
Proper citation: BioLemmatizer (RRID:SCR_000117) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 23,2022. A metagenomic open reading frame (ORF) finding tool for the prediction of protein coding genes in short, environmental DNA sequences with unknown phylogenetic origin. The resource is based on a two-stage machine learning approach that uses linear discriminants to extract features from the ORFs. An artificial neural network then combines the features and computes a gene probability for each ORF fragment.
Proper citation: Orphelia (RRID:SCR_000119) Copy
http://www.bioconductor.org/packages/release/bioc/html/ReQON.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Algorithm for recalibrating the base quality scores for aligned sequencing data in BAM format.
Proper citation: ReQON (RRID:SCR_000075) Copy
http://www.iro.umontreal.ca/~csuros/quadgt/
Software package for calling single-nucleotide variants in four sequenced genomes comprising a normal-tumor pair and the two parents. Genotypes are inferred using a joint model of parental variant frequencies, de novo germline mutations, and somatic mutations. The model quantifies the descent-by-modification relationships between the unknown genotypes by using a set of parameters in a Bayesian inference setting. Note that you can use it on any subset of the four related genomes, including parent-offspring trios, and normal-tumor pairs without parental samples.
Proper citation: QuadGT (RRID:SCR_000073) Copy
http://soap.genomics.org.cn/soapfuse.html
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on August 23,2022. An open source tool developed for genome-wide detection of fusion transcripts from human being paired-end RNA-Seq data. This tool is a part of a larger set of tools to efficiently align oligonucleotides onto reference sequences .
Proper citation: SOAPfuse (RRID:SCR_000078) Copy
http://www.gobics.de/fabian/treephyler.php
A software tool for fast taxonomic profiling of metagenomes.
Proper citation: Treephyler (RRID:SCR_000109) Copy
http://www.bioinformatics.babraham.ac.uk/projects/fastq_screen/
Software that allows you to screen a library of sequences in FastQ format against a set of sequence databases so you can see if the composition of the library matches with what you expect.
Proper citation: FastQ Screen (RRID:SCR_000141) Copy
http://www.bioconductor.org/packages/2.13/bioc/html/GenomicRanges.html
Software package that defines general purpose containers for storing genomic intervals as well as more specialized containers for storing alignments against a reference genome.
Proper citation: GenomicRanges (RRID:SCR_000025) Copy
http://www.bioconductor.org/packages/release/bioc/html/GEOquery.html
Software that establishes a bridge between GEO and BioConductor.
Proper citation: GEOquery (RRID:SCR_000146) Copy
Chemical 2D structure editor and viewer application/applet based on the Chemistry Development Kit (CDK).
Proper citation: JChemPaint (RRID:SCR_000095) Copy
https://github.com/BenLangmead/bsmooth-align
Software statistics and alignment pipeline that performs the alignment of bisulfite sequence reads and tabulates read-level methylation measurements.
Proper citation: BSmooth-align (RRID:SCR_000013) Copy
A generic format for DNA sequence data. The primary motivation for creating SRF has been to enable a single format capable of storing data generated by any DNA sequencing technology.
Proper citation: Sequence Read Format (RRID:SCR_000132) Copy
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