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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://discover.nci.nih.gov/cellminer/
Database and query tool designed for cancer research community to facilitate integration and study of molecular and pharmacological data for the NCI-60 cancerous cell lines. The NCI-60, panel of 60 diverse human cancer cell lines used by the Developmental Therapeutics Program of the U.S. National Cancer Institute to screen over 100,000 chemical compounds and natural products since 1990.
Proper citation: CellMiner (RRID:SCR_025648) Copy
Provides pharmacogenomics resource for study of cancer. Multiple tools are available, currently including the CellMiner family with CellMiner, CellMinerCDB (cross data-base), CellMinerCDB: Small Cell Lung Cancer (SCLC), CellMinerCDB: National Center for Advancing Translational Sciences (NCATS) andCellMinerCDB: Sarcoma. These sites include multiple cancerous cell lines sets and data types. In addition there is CIMMiner for cluster image maps and MIMminer, with several scholarly molecular interaction maps.
Proper citation: National Cancer Institute Genomics and Pharmacology Core Facility (RRID:SCR_025664) Copy
https://healthcaredelivery.cancer.gov/seermedicare/considerations/calculation.html
Portal provides SAS Macros to calculate comorbidity weights. Used to assist SEER-Medicare investigators with their analyses. NCI recommends use of the 2021 macro. The 2014 and 2000 versions are provided for those needing to reproduce prior results. These macros offer the option of including Medicare hospital (MedPAR) claims only, or also considering physician (NCH) and outpatient claims. The Rule-Out option is recommended in the latter situation. Note that diagnoses using ICD-10 codes, starting in October 2015, are not included in the 2000 and 2014 macros. NCI does not accept responsibility for the completeness or accuracy of the codes and weights used in the macros. Investigators may modify the macros if they wish to include different diagnosis codes or condition weights.
Proper citation: NCI Division of Cancer Control and Population Sciences SEER-Medicare Comorbidity SAS Macros (RRID:SCR_025810) Copy
https://genomics.ccr.cancer.gov/
Core provides access to genomic technologies and Next-Generation Sequencing. Provides DNA and RNA quality control services, user accessible instrumentation, training, consultation services, bioinformatics support, and secure data delivery management.
Proper citation: NCI Center for Cancer Research Genomics Core Facility (RRID:SCR_024754) Copy
http://www-lecb.ncifcrf.gov/NCISEM97/ncisem18.html
The Flicker image viewer is a Java applet which reads two images from the Internet and then displays them in the your Web browser. It allows you to enhance them in various ways and to compare them visually in a third window called the flicker window. The Open-source Flicker downloadable application is now available. The program uses the "flicker method" used in GELLAB with and with Xconf. The flicker method is the alternate display in the same visual space of two images being compared which are aligned by aligning similar morphologic features. Images may first be enhanced by spatial warping, pseudo 3-Dimensional projections, image sharpening, contrast enhancement and other transforms. The transformed images may then be presented using flickering. Flicker is a method for comparing images from different Internet sources on your Web browser. Scientists around the world often work on similar image data. More of this data is being published on the Internet each year. In the case of 2D protein electrophoretic gel images, maps identifying proteins in these gels are becoming increasingly available. Visually comparing 2D sample gels against these 2D gel database maps may suggest putative protein spot identification in many cases. Flicker was originally developed for comparing 2D protein gels across the Internet.
Proper citation: NCI Flicker Web Server. (RRID:SCR_003390) Copy
http://dtp.nci.nih.gov/branches/btb/services.html
National Cancer Institute Biorepositories provides information on the tumor repository, animal production program, and access to other NIH Repositories. A catalog of in vitro cell lines, transplantable animal and human tumors and microarrays, including ordering information, is available. In the Animal Production Program, rodents are supplied to Federal Institutions and to grantees/contractors with a current OLAW Assurance on file. Requests from international entities seeking rodent strains solely available from the NCI Animal Production Program must have an OLAW Assurance or current AAALACi accreditation and will be evaluated on a case-by-case basis. In general, the rodents are supplied to the following: * Researchers at NCI-Frederick * NIH on-campus laboratories * NIH/NCI funded research contracts * NIH/NCI funded grantees * Other government agencies To meet the above needs, animal production contracts plus quality control contracts are used. The animal production contracts are used to propagate the NIH sublines of the strains. Many of the strains produced are not available commercially and the NCI program is the sole source of several lines.
Proper citation: National Cancer Institute Biorepositories (RRID:SCR_004789) Copy
NIH initiative to support production of cDNA libraries, clones and 5'/3' sequences and to provide set of full-length (open reading frame) sequences and cDNA clones of expressed genes for Xenopus laevis and Xenopus tropicalis. Clones distribution is outsourced to for profit companies. Project concluded in September 2008. Resources generated by XGC are publicly accessible to biomedical research community. All sequences are deposited into GenBank.Corresponding clones are available through IMAGE clone distribution network. With conclusion of XGC project, GenBank records of XGC sequences will be frozen, without further updates. Since knowledge of what constitutes full-length coding region for some of genes and transcripts for which we have XGC clones will likely change in future, users planning to order XGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view relevant regions of genome (browsers) or gene-related information (Entrez Gene).
Proper citation: Xenopus Gene Collection (RRID:SCR_007023) Copy
Part of zebrafish genome project. ZGC project to produce cDNA libraries, clones and sequences to provide complete set of full-length (open reading frame) sequences and cDNA clones of expressed genes for zebrafish. All ZGC sequences are deposited in GenBank and clones can be purchased from distributors of IMAGE consortium. With conclusion of ZGC project in September 2008, GenBank records of ZGC sequences will be frozen, without further updates. Since definition of what constitutes full-length coding region for some of genes and transcripts for which we have ZGC clones will likely change in future, users planning to order ZGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view relevant regions of genome (browsers) or gene-related information (Entrez Gene).
Proper citation: Zebrafish Gene Collection (RRID:SCR_007054) Copy
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