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http://dartmouth.eagle-i.net/i/00000140-0bdb-4fa0-785a-dfc280000000

Core facility that provides the following services: Data and Analysis of large health care datasets.

The Data and Analytic Core (DAC) includes research analysts and programmers, research assistants, a data librarian, and a Director who reports to the Director of the Center for Health Policy Research and the DAC Advisory Committee. The DACs responsibilities are to maintain an extremely secure environment for health care datasets provided to Principal Investigators by the U.S. Centers for Medicare and Medicaid Services, state governments, and other organizations under data use agreements and licenses. The DAC works under the direction of faculty investigators who have specific permission to use the data to conducted research. The DAC consists of 15 analysts (and an additional 5 staff) with a combined 150 years of healthcare claims analytic experience and a mastery of a broad range of programming and statistical methods. New analysts undergo a comprehensive training program lasting the better part of 6 months to assure a strong foundation in Medicare data analytics.

Proper citation: Dartmouth Institute for Health Policy and Clinical Practice: Data and Analytic Core (RRID:SCR_009764) Copy   

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http://dartmouth.eagle-i.net/i/0000012e-5d0c-3250-a694-4a4a80000000

Core facility that provides the following services: Coding of data. The Dartmouth Media Research Lab (DMRL) specializes in the content coding of all types of media including movies, television programming and advertising. We have an extensive database of top box office hits from 1995 to the present. Past areas of research have included tobacco, alcohol, food, violence, and sexual activity. The team consists of two trained coders and a supervisor who ensures consistency and reliability.

Proper citation: Dartmouth Media Research Lab Shared Resource (RRID:SCR_009765) Copy   

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http://dartmouth.eagle-i.net/i/0000012b-00c3-cb86-6a59-ec4e80000000

The primary mission of the Biostatistics Shared Resource (BSR) is to improve the statistical aspects of cancer research at Dartmouth by providing expert statistical collaboration for research projects of Cancer Center members. Because every aspect of cancer research involves data, all research programs potentially may require the participation of the BSR. Areas of special faculty expertise include clinical trial design, longitudinal data, statistical methods for genomics and managing data, measurement error methods, nonlinear dose response modeling, quality of life data, decision sciences, cost effectiveness analysis, and diagnostic test assessment. Faculty and staff offices are located on the 8th floor of the Rubin building at Dartmouth-Hitchcock Medical Center (DHMC). The BSR maintains an extensive statistical software library providing access to all major statistical analysis platforms. Server and network access are provided through Cancer Center administration, DHMC, and Dartmouth College. The BSR collaborates closely with other shared resources for project development and monitoring through the Office of Clinical Research, and the Integrative Biology and Experimental and Translational Models Shared Resources.

Proper citation: Dartmouth Biostatistics Shared Resource (RRID:SCR_009760) Copy   

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https://cores.catalyst.harvard.edu/?uri_id=00000130-097b-7a38-de5a-673e80000000&navMode=cat,

The Center promotes further understanding of host-microbiome interactions in health and disease, emphasizing a focus on function to define causative effects of the microbiota in vivo and to harness this knowledge in developing new therapies, diagnostics and further commercial applications.

Proper citation: Massachusetts Host-Microbiome Center (RRID:SCR_009713) Copy   

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http://harvard.eagle-i.net/i/0000012a-2517-5e6f-5617-794280000000

Core facility that provides the following services: X-ray crystallography service, X-ray crystallography reference database access service, X-ray crystallographic data analysis and processing service, Access to x-ray crystallography using synchrotron radiation, X-ray crystallography advising and consultation service.

The X-ray Crystallography Facility located at 99 Brookline Ave. (Research North) was recently established as a core to serve the needs of investigators in the BIDMC and Harvard Medical School community interested in using structural biology as a tool in their research.

Proper citation: BIDMC X-ray Crystallography Core (RRID:SCR_009678) Copy   

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http://harvard.eagle-i.net/i/00000130-0974-6d4c-de5a-673e80000000

Core facility that provides the following services: Cell culture services, Cell line freezing, Transient transfection, FACS Analysis, n-Counter mRNA analysis. Provides technologies and resources required for studies on polarized epithelial cells that line mucosal surfaces. We provide specialized epithelial cell culture and gene manipulation services, customized materials and instrumentation, expert know-how, and training to facilitate structural and functional studies on polarized epithelial cell culture systems or mucosal intestinal tissue in situ.

Proper citation: CHB Epithelial Cell Biology Core (RRID:SCR_009712) Copy   

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http://harvard.eagle-i.net/i/0000012a-2518-e64e-5617-794280000000

Core facility that provides the following services: Real-Time PCR service, Real-time PCR training service.

Performs Real-Time-PCR and provides quantitative data on levels of gene expression. The Core comprises an ABI 7700 Sequence Detector System, equipped with all an investigator needs for experimental design/run and data processing.

Proper citation: BIDMC Real-Time PCR Core (RRID:SCR_009676) Copy   

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http://harvard.eagle-i.net/i/0000012a-2517-32d8-5617-794280000000

Core facility that provides the following services: DNA injection service, Embryonic stem cell injection service, Transgenic mouse line rescue service, Transgenic mouse embryo handling services, Mouse assisted reproductive services.

The Beth Israel Deaconess Transgenic Core Facility opened in October of 1991.The Transgenic Core is a state-of-art facility that produces genetically altered animals.

Proper citation: BIDMC Transgenic Core Facility (RRID:SCR_009677) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c4-d136-db6e-7a3f80000000

Core facility that provides the following services: In Vivo Magnetic Resonance Imaging (MRI), Quantitative Image Analysis: Standard Uptake Value (SUV), 3D Volume Measurements, Animal Handling Techniques: Blood Collection, Injections (IV, IP), Oral Gavage, Tumor Inoculation, Transcardiac Perfusion, etc., Whole-body and Tissue Cryosectioning, Ex Vivo Tissue Radioactivity Measurement.

Our goal is to provide state-of-the-art small animal imaging services to researchers in the Longwood Medical Area of Harvard Medical School. These services include multi-modality imaging, advanced data analysis, image fusion resources, and a satellite animal facility for longitudinal studies. A detailed description of our instruments and services are provided on our website, and we welcome questions and comments.

Proper citation: BIDMC Longwood Small Animal Imaging Core Facility (RRID:SCR_009670) Copy   

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http://harvard.eagle-i.net/i/0000012a-2513-da28-5617-794280000000

Core facility that provides the following services: Imaging consultation service, Image analysis service. The CRL was formed with the mission of improving our understanding of the structure and function of the brain and other organs of the human body, in order to improve our capacity to diagnose and treat disease. Members of the CRL achieve this by developing novel technologies and computational modeling strategies for understanding and interpreting radiological images.

Proper citation: CHB Computational Radiology Laboratory (RRID:SCR_009709) Copy   

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http://cdrewu.eagle-i.net/i/00000135-ca50-bd65-1a88-e81c80000000

The Vivarium is a facility dedicated to the humane care and use of laboratory animals.

Proper citation: CDU Vivarium (RRID:SCR_009704) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5db0-d3b1-55da-381e80000000

Core facility that provides the following services: Advanced ultrasound imaging. The mission of the Advanced Fetal Care Center (AFCC) is to provide the finest diagnosis and care for a mother carrying a baby with a congenital anomaly. For these families, our center offers entry to a continuum of care and support that extends throughout childhood--from prenatal diagnosis and counseling, through treatment and long-term follow-up. On rare occasions, our team will recommend and perform intervention during fetal life. Our physicians, who represent all pediatric subspecialty areas, work with a wide range of babies with anomalies. Together, they have developed ground-breaking procedures in fetal medicine and surgery.

Proper citation: CHB Advanced Fetal Care Center (RRID:SCR_009705) Copy   

•   Source: SciCrunch Registry

http://cdrewu.eagle-i.net/i/00000135-20b7-3e29-f836-7d1b80000000

Core facility that provides the following services: Morphometric study design, Tissue embedding and sectioning service, Tissue embedding, sectioning and microscopy training. The Morphometry and Stereology Laboratory is a service and training laboratory for the faculty, students, and staff of CDU and other interested researchers. The mission of the laboratory is to: 1) teach up-to-date stereology theory and practical morphometric techniques; 2) help design unbiased efficient morphometric studies; 3) train researchers to use the equipment and software available in the laboratory; 4) develop an outreach program for community students to visit a microscopy research laboratory; 5) organize stereology workshops for CDU personnel and other interested researchers.

Proper citation: CDU Morphometry and Stereology Laboratory (RRID:SCR_009703) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-0219-d555-b2b9-4d8780000000

Core facility that provides the following services: Clinical diagnosis services, Genomic sequencing service, ABI capillary sequencing service, Illumina next generation sequencing service, shRNA library sequencing service, High throughput genome sequencing, PCR to detection service, Plasmid sequencing service, Sequencing, Chip-Seq service, Digital Gene Expression Service, Nucleic acid library construction service, Next gen seq bioinformatics support service, Transcriptome and RNA-Seq service.

Proper citation: Harvard PCPGM DNA Sequencing Facility (RRID:SCR_009858) Copy   

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http://uccaribe.eagle-i.net/i/00000135-d3e6-439f-a272-8ee780000000

Core facility that provides the following services: Equipment support, Research software design. Is a core area housing major equipment such as ultracentrifuges, freezers, spectrophotometers, gamma counters, etc, as well as the centralized cell culture facility. The unit fosters equipment sharing, centralizes maintenance of equipment and provides repair for the equipment of all the projects.

Proper citation: UCC Common Instrumentation Area and Services (RRID:SCR_009851) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5870-e12d-55da-381e80000000

The Forsyth Center for Clinical and Translational Research (CCTR) is a unique clinical facility with 6 fully-equipped dental units and associated laboratories that are specifically dedicated to conduct clinical research in oral and related systemic diseases. Clinical trials following FDA guidelines are performed at all levels, from early phase 1 trials to large, multicenter definitive clinical trials, with the goal of improving outcomes and the long-term health of patients. We routinely conduct studies in the oral environment, that include standard clinical measurement protocols for dental caries, dental calculus, gingivitis, periodontal diseases, intraoral local anesthetic evaluation, tooth restoration and tooth whitening evaluation. In addition, the clinic is equipped for obtaining and processing microbiological samples, gingival crevice fluid samples, blood and saliva samples for analysis of bacteria, inflammatory mediators, as well as for genomic and proteomic analyses. Under the new leadership of Dr. Thomas Van Dyke, Vice President of Clinical Research at The Forsyth Institute, the Center proposes new goals/efforts in discovering new techniques, testing new ideas and searching for valuable biomarkers for preventing and treating periodontal diseases and associated systemic inflammatory conditions. The CCTR is actively involved with the design and conduct of clinical research under Good Clinical Practices for submission to regulatory agencies. It has a published international reputation in evaluating intraoral local drug delivery devices, oral diagnostic systems, local anesthesia, restorative materials, tooth whitening systems and the association of oral diseases with systemic conditions. Forsyth''s Institutional Review Board is a member of the Harvard Catalyst Regulatory Group and meets on a monthly basis providing complete review of clinical protocols.

Proper citation: Harvard Forsyth Center for Clinical and Translational Research (RRID:SCR_009847) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-60a9-25c8-c437-ff0b80000000

Core facility that provides the following services: MLV plasmid construction service, HIV plasmid construction service, Adenovirus plasmid construction service. The Harvard Gene Therapy Initiative was founded with the objective of promoting the use of gene therapy in both research and therapeutic applications and to conduct research developing new gene delivery vector technologies.

Proper citation: Harvard Gene Therapy Initiative Core (RRID:SCR_009848) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000135-5ed7-550c-be1e-73c480000000

The Small Molecule Mass Spectrometry Facility at the FAS Center for Systems Biology offers support for the analysis of a wide variety of analytes using mass spectrometry based techniques. We are located in the second basement (B2) level of the Northwest Laboratory building at 52 Oxford Street, Cambridge, MA 02138. We provide services for molecular formula confirmation (accurate mass measurement), structural elucidation (MS/MS) and quantitation of small molecules. In addition, we can assist you in the mass analysis of a wide variety of non-proteomics samples including metabolites, medium sized proteins and oligonucleotides. Please contact us and tell us about your samples prior to submission or use of our Open Access laboratory.

Proper citation: Harvard FAS Small Molecule Mass Spectrometry Facility (RRID:SCR_009845) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-a1a6-4291-55da-381e80000000

Core facility that provides the following services: Progamming and sequencing classes and training. Research Computing (RC) facilitates the advancement of complex research by providing leading edge computing services across the Faculty of Arts & Sciences (FAS). RC staff maintain expertise in constantly changing computing technologies, while ''speaking the language'' of the FAS researchers, to help them use computing more effectively.

Proper citation: Harvard FAS Research Computing Core (RRID:SCR_009844) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012f-e9eb-c410-de5a-673e80000000

The Neuroimaging facility has a 3-Tesla magnetic resonance imaging scanner for non-invasive human brain imaging. Our aim is to: * Provide functional and anatomic magnetic resonance imaging (MRI) to scientists studying human cognition, brain development and aging, and individual differences * Provide training for undergraduate and graduate students destined to become the next generation of neuroscientists * Pioneer innovative ways of imaging the human brain and is a first adopter of new neuroimaging technology, tools and applications * Develop and make available the data processing and visualization tools demanded by advancing neuroimaging technologies.

Proper citation: Harvard FAS Center for Brain Science - Neuroimaging Core Facility (RRID:SCR_009842) Copy   

•   Source: SciCrunch Registry