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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PhenoSpD
 
Resource Report
Resource Website
1+ mentions
PhenoSpD (RRID:SCR_016359) PSD data analysis software, data processing software, software application, software resource, software toolkit Software toolkit for phenotypic correlation estimation and multiple testing correction (Spectral Decomposition, SpD) for human phenome using genome-wide association study (GWAS) summary statistics. It is a command line R based tool. spectral, decomposition, matrice, phenotypic, correlation, estimation, multiple, testing, correction, human, phenome, genome, summary, statistic, decomposition, matrice, genomics is related to: University of Bristol; Bristol; United Kingdom
is related to: R Project for Statistical Computing
Free, Available for download, Freely available SCR_016359 Pheno Spectral Decomposition, PhenoSpD 2026-08-29 11:25:16 6
GASVPro
 
Resource Report
Resource Website
1+ mentions
GASVPro (RRID:SCR_005259) GASVPro data analysis software, data processing software, sequence analysis software, software application, software resource Software tool combining both paired read and read depth signals into probabilistic model which can analyze multiple alignments of reads. Used to find structural variation in both normal and cancer genomes using data from variety of next-generation sequencing platforms. Used to predict structural variants directly from aligned reads in SAM/BAM format.Combines read depth information along with discordant paired read mappings into single probabilistic model two common signals of structural variation. When multiple alignments of read are given, GASVPro utilizes Markov Chain Monte Carlo procedure to sample over the space of possible alignments. structural variation, genome, genomics, alignment, sequencing, variant, variation, detection, dna, paired, end, read, sequence is listed by: OMICtools
is related to: GASV
has parent organization: Brown University; Rhode Island; USA
Burroughs Wellcome Career Award at the Scientific Interface ;
NHGRI R01 HG5690
PMID:22452995 Free, Available for download, Freely available OMICS_00317 http://code.google.com/p/gasv/downloads/list SCR_005259 GASVPro: Geometric Analysis of Structural Variants 2026-08-29 11:22:18 8
PRISM (Stanford database)
 
Resource Report
Resource Website
10000+ mentions
PRISM (Stanford database) (RRID:SCR_005375) PRISM analysis service resource, data analysis service, data or information resource, database, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5,2022.Tool that predicts interactions between transcription factors and their regulated genes from binding motifs. Understanding vertebrate development requires unraveling the cis-regulatory architecture of gene regulation. PRISM provides accurate genome-wide computational predictions of transcription factor binding sites for the human and mouse genomes, and integrates the predictions with GREAT to provide functional biological context. Together, accurate computational binding site prediction and GREAT produce for each transcription factor: 1. putative binding sites, 2. putative target genes, 3. putative biological roles of the transcription factor, and 4. putative cis-regulatory elements through which the factor regulates each target in each functional role., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. genomic, transcription factor, function, transcription factor binding site, transcription factor regulator, biological role, target gene, target genomic region, genome, FASEB list is listed by: OMICtools
is listed by: SoftCite
is related to: GREAT: Genomic Regions Enrichment of Annotations Tool
has parent organization: Stanford University School of Medicine; California; USA
PMID:23382538 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00489 SCR_005375 Predicting Regulatory Information from Single Motifs 2026-08-29 11:22:19 40822
Ergatis
 
Resource Report
Resource Website
1+ mentions
Ergatis (RRID:SCR_005377) Ergatis software resource A web interface and scalable software system for bioinformatics workflows that is used to create, run, and monitor reusable computational analysis pipelines. It contains pre-built components for common bioinformatics analysis tasks. These components can be arranged graphically to form highly-configurable pipelines. Each analysis component supports multiple output formats, including the Bioinformatic Sequence Markup Language (BSML). The current implementation includes support for data loading into project databases following the CHADO schema, a highly normalized, community-supported schema for storage of biological annotation data. Ergatis uses the Workflow engine to process its work on a compute grid. Workflow provides an XML language and processing engine for specifying the steps of a computational pipeline. It provides detailed execution status and logging for process auditing, facilitates error recovery from point of failure, and is highly scalable with support for distributed computing environments. The XML format employed enables commands to be run serially, in parallel, and in any combination or nesting level. workflow, bioinformatics, workflow management, pipeline, computation, genomics, genome, processing is listed by: OMICtools
has parent organization: SourceForge
has parent organization: University of Maryland School of Medicine; Maryland; USA
PMID:20413634 Artistic License OMICS_01140 SCR_005377 ergatis: workflow creation and monitoring interface 2026-08-29 11:22:25 2
CREST
 
Resource Report
Resource Website
50+ mentions
CREST (RRID:SCR_005257) CREST software resource An algorithm for detecting genomic structural variations at base-pair resolution using next-generation sequencing data. CREST uses pieces of DNA called soft clips to find structural variations. Soft clips are the DNA segments produced during sequencing that fail to properly align to the reference genome as the sample genome is reassembled. CREST uses the soft clips to precisely identify sites of chromosomal rearrangement or where pieces of DNA are inserted or deleted. genome, structural variation, next-generation sequencing, soft clip is listed by: OMICtools
has parent organization: Pennsylvania State University
PMID:21666668 OMICS_00312 SCR_005257 2026-08-29 11:22:10 57
MolBioLib
 
Resource Report
Resource Website
MolBioLib (RRID:SCR_005372) MolBioLib software resource A compact, portable, and extensively tested C++11 software framework and set of applications tailored to the demands of next-generation sequencing data and applicable to many other applications. It is designed to work with common file formats and data types used both in genomic analysis and general data analysis. A central relational-database-like Table class is a flexible and powerful object to intuitively represent and work with a wide variety of tabular datasets, ranging from alignment data to annotations. MolBioLib includes programs to perform a wide variety of analysis tasks such as computing read coverage, annotating genomic intervals, and novel peak calling with a wavelet algorithm. This package assumes fluency in both UNIX and C++. c++, next-generation sequencing, genomic, analysis, genome is listed by: OMICtools
has parent organization: SourceForge
PMID:22815363 OMICS_01145 SCR_005372 MolBioLib: C++11 framework for rapid develop and deploy of bioinformatic tasks 2026-08-29 11:22:19 0
BioExtract
 
Resource Report
Resource Website
10+ mentions
BioExtract (RRID:SCR_005397) BioExtract service resource An open, web-based system designed to aid researchers in the analysis of genomic data by providing a platform for the creation of bioinformatic workflows. Scientific workflows are created within the system by recording tasks performed by the user. These tasks may include querying multiple, distributed data sources, saving query results as searchable data extracts, and executing local and web-accessible analytic tools. The series of recorded tasks can then be saved as a reproducible, sharable workflow available for subsequent execution with the original or modified inputs and parameter settings. Integrated data resources include interfaces to the National Center for Biotechnology Information (NCBI) nucleotide and protein databases, the European Molecular Biology Laboratory (EMBL-Bank) non-redundant nucleotide database, the Universal Protein Resource (UniProt), and the UniProt Reference Clusters (UniRef) database. The system offers access to numerous preinstalled, curated analytic tools and also provides researchers with the option of selecting computational tools from a large list of web services including the European Molecular Biology Open Software Suite (EMBOSS), BioMoby, and the Kyoto Encyclopedia of Genes and Genomes (KEGG). The system further allows users to integrate local command line tools residing on their own computers through a client-side Java applet. nucleotide sequence, protein sequence, viridiplantae, viridiplantae protein, nucleotide, sequence, protein, viridiplantae, workflow, software, database, bioinformatics, platform, genome, genomic analysis, analytic tool is listed by: OMICtools
is listed by: SoftCite
is related to: NCBI Nucleotide
is related to: NCBI Protein Database
is related to: UniProt
is related to: UniRef
is related to: EMBOSS
is related to: BioMoby
is related to: KEGG
has parent organization: Indiana University; Indiana; USA
has parent organization: University of South Dakota; South Dakota; USA
NSF 0090732;
NSF IOS-1126481
PMID:21546552
PMID:20865520
PMID:20150665
PMID:20054995
OMICS_01138 SCR_005397 BioExtract Server 2026-08-29 11:22:25 12
SPLITREAD
 
Resource Report
Resource Website
1+ mentions
SPLITREAD (RRID:SCR_005264) SPLITREAD software resource Software for detecting INDELs (small insertions and deletion with size less than 50bp) as well as large deletions that are within the coding regions from the exome sequencing data. It also can be applied to the whole genome sequencing data. deletion, insertion, indel, genome, exome is listed by: OMICtools
is related to: drFAST
is related to: mrFAST
is related to: mrsFAST
is related to: VariationHunter
is related to: NovelSeq
is related to: mrCaNaVaR
has parent organization: SourceForge
OMICS_00323 SCR_005264 SPLITREAD - Split read based INDEL/SV Caller 2026-08-29 11:22:11 3
Hydra
 
Resource Report
Resource Website
100+ mentions
Hydra (RRID:SCR_005260) Hydra software resource Software that detects structural variation (SV) breakpoints by clustering discordant paired-end alignments whose signatures corroborate the same putative breakpoint. Hydra can detect breakpoints caused by all classes of structural variation. Moreover, it was designed to detect variation in both unique and duplicated genomic regions; therefore, it will examine paired-end reads having multiple discordant alignments. Hydra does not attempt to classify SV breakpoints based on the mapping distances and orientations of each breakpoint cluster, it merely detects and reports breakpoints. This is an intentional decision, as it was observed that in loci affected by complex rearrangements, the type of variant suggested by the breakpoint signature is not always correct. Hydra does report the orientations, distances, number of supporting read-pairs, etc., for each breakpoint. It is suggested that downstream methods be used to classify variants based on the genomic features that they overlap and the co-occurrence of other breakpoints. For example, they developed BEDTools for exactly this purpose and the breakpoints reported by Hydra are in the BEDPE format used by BEDTools. Future releases of Hydra will include scripts that assist in the classification process. structural variation, genome, genomic, breakpoint, c++, cnv, pem, paired-end, segmental duplication, rearrangement is listed by: OMICtools
is listed by: SoftCite
is related to: BEDTools
has parent organization: Google Code
has parent organization: University of Virginia; Virginia; USA
OMICS_00318 SCR_005260 hydra-sv 2026-08-29 11:22:11 119
MAKER Web Annotation Service
 
Resource Report
Resource Website
1+ mentions
MAKER Web Annotation Service (RRID:SCR_005318) MWAS data access protocol, production service resource, service resource, software resource, web service The MAKER Web Annotation Service (MWAS) is an easily configurable web-accessible genome annotation pipeline. It''''s purpose is to allow research groups with small to intermediate amounts of eukaryotic and prokaryotic genome sequence (i.e. BAC clones, small whole genomes, preliminary sequencing data, etc.) to independently annotate and analyze their data and produce output that can be loaded into a genome database. MWAS is build on the stand alone genome annotation pipeline MAKER, and users who wish to annotate larger datasets and whole genomes are free to download MAKER for use on their own systems. MWAS identifies repeats, aligns ESTs and proteins to a genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence-based quality values. MWAS can also automatically train popular gene prediction algorithms for use on new genomes for which pre-existing information is limited. MAKER is a member of the Generic Model Organism Database (GMOD) project and output produced by this site can be directly used with other GMOD tools. Annotations can be directly viewed online by the user via GBrowse, JBrowse, and Apollo, or they can be downloaded for local analysis and integration into a genome database. MWAS also supplies summary statistics on sequence features via the Sequence Ontology tool SOBA. MWAS should prove especially useful for emerging model organism genome projects with minimal bioinformatics expertise and computer resources, since a user can produce final genome annotations without having to install and configure any software locally. data management, human genome map, genome annotation, annotation, curation, genome, sequence is related to: MAKER
has parent organization: University of Utah; Utah; USA
nlx_144374 SCR_005318 2026-08-29 11:22:18 7
GEM
 
Resource Report
Resource Website
10+ mentions
GEM (RRID:SCR_005339) GEM software resource Java software for studying protein-DNA interaction using ChIP-seq / ChIP-exo data. It links binding event discovery and motif discovery with positional priors in the context of a generative probabilistic model of ChIP data and genome sequence, resolves ChIP data into explanatory motifs and binding events at unsurpassed spatial resolution. GEM reciprocally improves motif discovery using binding event locations, and binding event predictions using discovered motifs. chip-seq, chip-exo, genome, event, motif, protein-dna interaction, java, transcription factor, genome sequence, motif discovery, binding event calling is listed by: OMICtools
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
PMID:22912568 OMICS_00441 SCR_005339 Genome wide Event finding and Motif discovery, GEM: ChIP-Seq and ChIP-exo analysis tool 2026-08-29 11:22:12 12
Fulcrum
 
Resource Report
Resource Website
1+ mentions
Fulcrum (RRID:SCR_005523) Fulcrum software resource Software to collapse identical and near-identical Illumina and 454 reads (such as those from PCR clones) into single error-corrected sequences; it can process paired-end as well as single-end reads. Fulcrum is customizable and can be deployed on a single machine, a local network or a commercially available MapReduce cluster, and it has been optimized to maximize ease-of-use, cross-platform compatibility and future scalability. Sequence datasets have been collapsed by up to 71%, and the reduced number and improved quality of the resulting sequences allow assemblers to produce longer contigs while using less memory. illumina, 454, read, paired-end read, single-end read, high-throughput sequencing, redundant read, genome, transcriptome, ultra high throughput sequencing is listed by: OMICtools
has parent organization: Stanford University School of Medicine; California; USA
PMID:22419786 BSD-like license OMICS_01049 http://pringlelab.stanford.edu/protocols.html SCR_005523 Fulcrum Read Collapser 2026-08-29 11:22:22 4
MicrobesOnline
 
Resource Report
Resource Website
100+ mentions
MicrobesOnline (RRID:SCR_005507) MicrobesOnline analysis service resource, data analysis service, data or information resource, database, production service resource, service resource, software resource, source code MicrobesOnline is designed specifically to facilitate comparative studies on prokaryotic genomes. It is an entry point for operon, regulons, cis-regulatory and network predictions based on comparative analysis of genomes. The portal includes over 1000 complete genomes of bacteria, archaea and fungi and thousands of expression microarrays from diverse organisms ranging from model organisms such as Escherichia coli and Saccharomyces cerevisiae to environmental microbes such as Desulfovibrio vulgaris and Shewanella oneidensis. To assist in annotating genes and in reconstructing their evolutionary history, MicrobesOnline includes a comparative genome browser based on phylogenetic trees for every gene family as well as a species tree. To identify co-regulated genes, MicrobesOnline can search for genes based on their expression profile, and provides tools for identifying regulatory motifs and seeing if they are conserved. MicrobesOnline also includes fast phylogenetic profile searches, comparative views of metabolic pathways, operon predictions, a workbench for sequence analysis and integration with RegTransBase and other microbial genome resources. The next update of MicrobesOnline will contain significant new functionality, including comparative analysis of metagenomic sequence data. Programmatic access to the database, along with source code and documentation, is available at http://microbesonline.org/programmers.html. microbe, genome, bacteria, archaea, fungi, prokaryote, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
DOE DE-AC02-05CH11231 PMID:19906701 nlx_144607, biotools:microbesonline https://bio.tools/microbesonline SCR_005507 Microbial Genomics Database, Microbes Online 2026-08-29 11:22:17 166
DiProGB
 
Resource Report
Resource Website
1+ mentions
DiProGB (RRID:SCR_005651) DiProGB software resource Genome browser that encodes the genome sequence by physico-chemical dinucleotide properties such as stacking energy, melting temperature or twist angle. Analyses can be performed for the + and ?, as well as for the double strand. genome, browser, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Dinucleotide Property Database
PMID:19605418 Free, Freely available biotools:diprogb, OMICS_00880 https://bio.tools/diprogb SCR_005651 DiProGB - The Dinucleotide Properties Genome Browser, Dinucleotide Properties Genome Browser 2026-08-29 11:22:24 4
Bismark
 
Resource Report
Resource Website
1000+ mentions
Bismark (RRID:SCR_005604) Bismark software resource Software tool to map bisulfite converted sequence reads and determine cytosine methylation states. Flexible aligner and methylation caller for Bisulfite-Seq applications. Used to map bisulfite treated sequencing reads to genome of interest and perform methylation calls in single step. Map bisulfite treated sequence reads, determine cytosine methylation states, genome, sequence reads, perform methylation calls, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Babraham Institute
PMID:21493656
DOI:10.1093/bioinformatics/btr167
Free, Available for download, Freely available biotools:bismark, OMICS_00575 https://github.com/FelixKrueger/Bismark, https://bio.tools/bismark https://sources.debian.org/src/bismark/ SCR_005604 2026-08-29 11:22:27 1200
Hepatitis C Virus Database (HCVdb)
 
Resource Report
Resource Website
1+ mentions
Hepatitis C Virus Database (HCVdb) (RRID:SCR_005718) HCVdb, analysis service resource, data analysis service, data or information resource, database, production service resource, service resource The Hepatitis C Virus Database (HCVdb) is a cooperative project of several groups with the mission of providing to the scientific community studying the hepatitis C virus a comprehensive battery of informational and analytical tools. The Viral Bioinformatics Resource Center (VBRC), the Immune Epitope Database and Analysis Resource (IEDB), the Broad Institute Microbial Sequencing Center (MSC), and the Los Alamos HCV Sequence Database (HCV-LANL) are combining forces to acquire and annotate data on Hepatitis C virus, and to develop and utilize new tools to facilitate the study of this group of organisms. hepatitis c, hepatitis c virus, genome, gene, virus, ortholog comparison, ortholog has parent organization: VBRC Hepatitis C virus NIAID contract HHSN266200400036C nlx_149175 SCR_005718 Hepatitis C Viral Database 2026-08-29 11:22:25 4
Staden Package
 
Resource Report
Resource Website
50+ mentions
Staden Package (RRID:SCR_005629) software resource A fully developed set of DNA sequence assembly (Gap4 and Gap5), editing and analysis tools (Spin) for Unix, Linux, MacOSX and MS Windows. c, unix/linux, sequence assembly, dna/protein analysis, spin, sequence alignment, genome, genome viewer, c++, fortran, tcl, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:20513662
DOI:10.1093/bioinformatics/btq268
BSD License OMICS_00894, biotools:staden https://bio.tools/staden, https://sources.debian.org/src/staden/ SCR_005629 Staden Package 2026-08-29 11:22:24 87
BLASTatlas - Mapping of whole genome homology
 
Resource Report
Resource Website
10+ mentions
BLASTatlas - Mapping of whole genome homology (RRID:SCR_005891) BLASTatlas data access protocol, software resource, web service The BLASTatlas is a tool that is useful for mapping and visualizing whole genome homology of genes and proteins within a reference strain compared to other strains or species of one or more prokaryotic organisms using either blastp, blastn, tblastn, or blastx. DNA structural information is also included in the atlas to visualize the DNA chromosomal context of regions. Additional information can be added to these plots. The tool is SOAP compliant and WSDL (web services description language) files are available with programming examples available in Perl. The resolution is per-residue or per nucleotide depending on the regime of the blast search: For each annotation in the reference genome, the best hit in the database genome is found using one of the above algorithms. Each matching or mismatching residue/nucleotide of the best hit (based on BLAST score) is then mapped back to the genome sequence, using the coordinates provided in the annotations. By providing an interoperable method to carry out whole genome visualization of homology, this service offers bioinformaticians as well as biologists an easy-to-adopt workflow that can be directly called from the programming language of the user, hence enabling automation of repeated tasks. This tool can be relevant in many pangenomic as well as in metagenomic studies, by giving a quick overview of clusters of insertion sites, genomic islands and overall homology between a reference sequence and a data set. genome, homology, dna, proteome, orf, blastp, blastn, tblastn, blastx, residue, nucleotide has parent organization: Technical University of Denmark; Lyngby; Denmark PMID:18414733 nlx_149461 SCR_005891 2026-08-29 11:22:30 13
InterProScan
 
Resource Report
Resource Website
5000+ mentions
InterProScan (RRID:SCR_005829) analysis service resource, data access protocol, data analysis service, data analysis software, data processing software, production service resource, service resource, software application, software resource, web service Software package for functional analysis of sequences by classifying them into families and predicting presence of domains and sites. Scans sequences against InterPro's signatures. Characterizes nucleotide or protein function by matching it with models from several different databases. Used in large scale analysis of whole proteomes, genomes and metagenomes. Available as Web based version and standalone Perl version and SOAP Web Service. functional, analysis, sequence, protein, nucleotide, predict, presence, domain, site, proteome, genome, metagenome, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Gene Ontology
is related to: RARTF
is related to: InterPro
is related to: LegumeIP
is related to: UniProtKB
has parent organization: European Bioinformatics Institute
Biotechnology and Biological Sciences Research Council ;
EMBL ;
European Union
PMID:15980438
PMID:17202162
PMID:24451626
Free, Available for download, Freely available OMICS_01479, biotools:interproscan_4, nlx_149337 https://www.ebi.ac.uk/interpro/download.html, https://bio.tools/interproscan_4 SCR_005829 InterProScan Sequence Search, InterProScan 2, InterProScan 3, InterProScan 4, InterProScan 5 2026-08-29 11:22:25 7512
UCSC Genome Browser
 
Resource Report
Resource Website
10000+ mentions
Rating or validation data
UCSC Genome Browser (RRID:SCR_005780) data or information resource, database, portal, project portal, service resource Portal to interactively visualize genomic data. Provides reference sequences and working draft assemblies for collection of genomes and access to ENCODE and Neanderthal projects. Includes collection of vertebrate and model organism assemblies and annotations, along with suite of tools for viewing, analyzing and downloading data. Reference, sequence, assembly, collection, genome, visualize, genomic, data, ENCODE, Neanderthal, project, sequencing is used by: VizHub
is used by: Blueprint Epigenome
is used by: QmRLFS-finder
is used by: International Human Epigenome Consortium Data Portal
is used by: iPiG
is listed by: re3data.org
is listed by: OMICtools
is listed by: Educational Resources in Neuroscience
is listed by: SoftCite
is related to: HEXEvent
is related to: PicTar
is related to: Phenotree
is related to: Enhancer Trap Line Browser
is related to: CistromeFinder
is related to: ENCODE
is related to: Human Epigenome Atlas
is related to: ENCODE
is related to: BigWig and BigBed
is related to: PhenCode
is related to: doRiNA
is related to: ISCA Consortium
is related to: WashU Epigenome Browser
is related to: CRISPOR
is related to: liftOver
is related to: kent
has parent organization: University of California at Santa Cruz; California; USA
works with: TarBase
works with: bedGraphToBigWig
Alfred P. Sloan Foundation ;
CISI ;
David and Lucille Packard Foundation ;
DOE ;
HHMI ;
NHGRI ;
NIGMS GM52848;
NIH ;
NSF DBI 9809007;
UC BIOTEuropean UnionH
PMID:12045153
PMID:22908213
PMID:23155063
OMICS_00926, SCR_017502, nif-0000-03603, SciEx_217, SCR_012479, r3d100010243 http://genome.cse.ucsc.edu, https://doi.org/10.17616/R3RK5C SCR_005780 The Human Genome Browser at UCSC, UCSC Genome Browser Group, University of California at Santa Cruz Genome Browser, UCSC Genome Bioinformatics 2026-08-29 11:22:26 11041

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