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http://www.som.soton.ac.uk/research/geneticsdiv/epidemiology/chromscan/
A statistical based program for association mapping of disease genes. It utilises the Malecot model and the linkage disequilibrium (LD) map for the candidate region to analyse the genotypes derive from large sample of matched cases and controls. (entry from Genetic Analysis Software)
Proper citation: CHROMSCAN (RRID:SCR_013131) Copy
http://mayoresearch.mayo.edu/mayo/research/schaid_lab/software.cfm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 24,2023. Software application to compute composite measures of linkage disequilibrium, their variances and covariances, and statistical tests, for all pairs of alleles from two loci when linkage phase is unkown. An extension of Weir and Cockerham (1989) to apply to multi-allelic loci. (entry from Genetic Analysis Software)
Proper citation: COMPOSITELD (RRID:SCR_013132) Copy
http://faculty.washington.edu/eathomp/Anonftp/PANGAEA/BOREL/
Software application for inference of genealogical relationships from genetic data, including sibship inference.
Proper citation: BOREL (RRID:SCR_013135) Copy
http://mayoresearch.mayo.edu/mayo/research/schaid_lab/software.cfm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 24,2023. Software application for statistical methods for disease and genetic marker associations using cases and their parents. These methods include an extension of the transmission/disequilibrium test (TDT) for multiple marker alleles, as well as additional general tests sensitive to associations that depend on dominant or recessive genetic mechanisms. (entry from Genetic Analysis Software)
Proper citation: GASSOC (RRID:SCR_013136) Copy
http://dlin.web.unc.edu/software/SNPMStat/
A command-line program for the statistical analysis of SNP-disease association in case-control/cohort/cross-sectional studies with potentially missing genotype data. SNPMStat allows the user to estimate or test SNP effects and SNP-environment interactions by maximizing the (observed-data) likelihood that properly accounts for phase uncertainty, study design and gene-environment dependence. For SNPs without missing data, the program performs the standard association analysis. For typed SNPs with missing data or untyped SNPs, the program performs the maximum-likelihood analysis. (entry from Genetic Analysis Software)
Proper citation: SNPMSTAT (RRID:SCR_013339) Copy
http://www.cbil.ece.vt.edu/ResearchOngoingSNP.htm
Software application (entry from Genetic Analysis Software)
Proper citation: MECPM (RRID:SCR_013341) Copy
http://www.bios.unc.edu/~lin/software/MAOS/
Software application that implements valid and efficient statistical methods for meta-analysis of genomewide association studies with overlapping subjects. The current release performs logistic regression analysis of individual level data under the additive mode of inheritance. Data from genome-wide association studies are often analyzed jointly for the purposes of combining information from multiple studies of the same disease or comparing results across different disorders. In many instances, the same subjects appear in multiple studies. Failure to account for overlapping subjects can greatly inflate type I error when combining results from multiple studies of the same disease and can drastically reduce power when comparing results across different disorders. (entry from Genetic Analysis Software)
Proper citation: MAOS (RRID:SCR_013351) Copy
http://chgr.mc.vanderbilt.edu/page/gist
Software package to test if a marker can account in part for the linkage signal in its region. There are two versions of the software: Windows and Linux/Unix.
Proper citation: Genotype-IBD Sharing Test (RRID:SCR_006257) Copy
http://www003.upp.so-net.ne.jp/pub/publications.html#sl
Software application for inkage disequilibrium grouping of single nucleotide polymorphisms (SNPs) reflecting haplotype phylogeny for efficient selection of tag SNPs. (entry from Genetic Analysis Software)
Proper citation: LDGROUP (RRID:SCR_006282) Copy
http://www.homepages.ed.ac.uk/pmckeigu/pooling/poolscore.htm
Software program for analysis of case-control genetic association studies using allele frequency measurements on DNA pools (entry from Genetic Analysis Software)
Proper citation: POOLSCORE (RRID:SCR_007514) Copy
http://www-gene.cimr.cam.ac.uk/clayton/software/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 12,2023. Software application that tests for association between genetic marker and disease by examining the transmission of markers from parents to affected offspring. The main features which differ from other similar programs are: (1) It can deal with transmission of multi-locus haplotypes, even if phase is unknown, and (2) Parental genotypes may be unknown. (entry from Genetic Analysis Software)
Proper citation: TRANSMIT (RRID:SCR_007571) Copy
http://gaow.github.io/genetic-analysis-software/l/linkage---ceph/
Software application (entry from Genetic Analysis Software)
Proper citation: LINKAGE - CEPH (RRID:SCR_007048) Copy
http://compgen.rutgers.edu/multimap.shtml
Software program for automated construction of genetic maps (entry from Genetic Analysis Software)
Proper citation: MULTIMAP (RRID:SCR_007168) Copy
https://github.com/gaow/genetic-analysis-software/blob/master/pages/MAPMAKER%26SIBS.md
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 22, 2016. Data analysis software for complete multipoint analysis.
Proper citation: MAPMAKER/SIBS (RRID:SCR_008012) Copy
http://www.stat.washington.edu/thompson/Genepi/MORGAN/Morgan.shtml
Software programs for segregation and linkage analysis, using a variety of Markov chain Monte Carlo (MCMC) methods. Includes MCMC methods for multilocus gene identity by descent (including homozygosity mapping) and Monte Carlo Lod scores. Also, other programs for EM analysis of quantitative traits.
Proper citation: MORGAN (RRID:SCR_006906) Copy
http://www.pierroton.inra.fr/genetics/labo/Software/Famoz/index.html
Software application that uses likelihood calculation and simulation to perform parentage studies with codominant, dominant, cytoplasmic markers or combinations of the different types (entry from Genetic Analysis Software)
Proper citation: FAMOZ (RRID:SCR_007477) Copy
http://www.mds.qmw.ac.uk/statgen/dcurtis/software.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5th,2023. Software application that uses Monte Carlo method for assessing significance of a case-control association study with multi-allelic marker. (entry from Genetic Analysis Software).
Proper citation: CLUMP (RRID:SCR_007476) Copy
http://darwin.uvigo.es/software/treescan.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. Software application that is intended to provide p-values for the hypothesis of association between evolutionary clades and continuous traits, using haplotype trees. (entry from Genetic Analysis Software)
Proper citation: TREESCAN (RRID:SCR_007108) Copy
http://pngu.mgh.harvard.edu/purcell/whap/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 24, 2015. This package is no longer supported. The majority of the functionality for conditional haplotype tests in population-based samples has been implemented in PLINK, with a better interface and more robust, faster computation: please use that from now on. Software tool to perform haplotype-based association analysis, for quantitative and qualitative traits, in population and family samples, using single nucleotide polymorphism or multiallelic marker data. What whap can do: * Analyze quantitative and qualitative traits * Handle unrelated individuals and/or parent-offspring trio data * Perform a regression-based haplotype association test for SNP data * Perform a secondary test based on pairwise haplotype similarity * Phase genotype data using a standard E-M approach, and handle ambiguity in E-M inferred haplotypes * Include covariates and moderator variables * Flexibly constrain effects across haplotypes to tested nested models * Perform a robust within-family test when parental genotypes are present * Analyze multiallelic markers (new) * Use dominant or recessive (new) genetic models (new)
Proper citation: Whap (RRID:SCR_007103) Copy
http://mga.bionet.nsc.ru/soft/mgamapf2/
Software application that map QTLs in F-2 intercross in model organisms (entry from Genetic Analysis Software)
Proper citation: MGA-MAPF2 (RRID:SCR_008108) Copy
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