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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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https://www.thermofisher.com/order/catalog/product/313001R#/313001R

Genetic analyzer can run sequencing and fragment analysis applications including microsatellite analysis, AFLP, LOH, SNP validation, and SNP screening. Maintenance time is reduced by eliminating manual syringe washing and filling with automated polymer delivery. Can increase data quality for sequencing and fragment analysis applications by longer read length, and higher resolution with shorter run times. Uses 96- or 384-well plates with four capillary array.

Proper citation: Thermo Fisher: Applied Biosystems: 3130 Genetic Analyzer (RRID:SCR_018046) Copy   


https://timothyspringer.org/files/tas/files/biacore3000-instrument.pdf

Biacore 3000 processing unit is an established, label-free system for detailed studies of biomolecular interactions. The system delivers comprehensive characterization of the interaction, answers questions about the rate constants, affinity, specificity, and determines the active concentration of components. The ability to recover and transfer interaction partners directly to MALDI targets for identification and further characterization makes the system highly applicable to fast identification of unknown interactants.

Proper citation: GE: Biacore 3000 Real Time Biomolecular Interaction Analyzer (RRID:SCR_018044) Copy   


https://www.agilent.com/en/product/automated-electrophoresis/bioanalyzer-systems/bioanalyzer-instrument/2100-bioanalyzer-instrument-228250

Bioanalyzer system is automated electrophoresis tool that provides an analytical evaluation of various samples types in many workflows, including next generation sequencing NGS, gene expression, biopharmaceutical, and gene editing research. Digital data is provided in timely manner and delivers assessment of sizing, quantitation, integrity and purity from DNA, RNA, and proteins. Minimal sample volumes are required for accurate result, and data may be exported in many different formats.

Proper citation: Agilent: 2100 Bioanalyzer Instrument (RRID:SCR_018043) Copy   


http://www.thunderbiosci.co.kr/wp-content/uploads/2017/07/Apollo-324_brochure.pdf

Compact benchtop platform that enables rapid and full walk-away automation of next generation sequencing applications. Paired with PrepX reagents, Apollo 324 line offers complete sample-toanswer solution for NGS library prep. Apollo 324 automated protocols and PrepX reagent kits combine liquid handling and proven chemistries to produce high quality libraries for all major NGS platforms. System provides complete, walkaway solution using validated protocols and chemistries that produce consistent libraries for DNA-seq, RNA-seq, and ChIP-seq applications.

Proper citation: Wafergen: Apollo 324 NGS Library Prep (RRID:SCR_018027) Copy   


http://nufab.northwestern.edu

Facility provides nanofabrication equipment and technical expertise.Supports research in all areas of science, engineering, medicine, and interdisciplinary fields. Equipment is located in clean room with laminar airflow and includes 3D Optical Profiler Zygo,Atomic Force Microscope Bruker Edge,Contact Angle Measurement VCA Optima XE,Electrical Test Station,Microscope Nikon LV150,Reflectometer Filmetrics F20,Spectroscopic Ellipsometer J.A. Woollam alpha-SE,Stylus Profilometer Veeco Dektak-8,Atomic Layer Deposition Arradiance GEMStar XT-P,E-beam Evaporator AJA,Parylene Coater SCS Labcoter2 Parylene Deposition System,Plasma Enhanced Chemical Vapor Deposition (PECVD) STS LpX CVD,Sputter I AJA Orion,Sputter II AJA Orion,Thermal Evaporator, Denton Vacuum Explorer 14,ETCHING ASHING,Deep Reactive Ion Etcher (DRIE) ,STS LpX Pegasus,Plasma Cleaner ,Samco PC-300,Reactive Ion Etcher (RIE) ,Samco RIE-10NR,Xenon Difluoride Etcher ,Xactix,Furnace ,Tystar,Rapid Thermal Processor ,AW-610,Laser Cutter, LPKF ProtoLaser R,Wire Bonder -Ball- iBond5000,Wire Bonder ,Wedge West Bond 747677E,Convection Ovens Blue M DCC-146-C-ST35,Mask Aligner ,Suss MABA6,Mask Aligner ,Suss MJB4,Maskless Aligner , Heidelberg MLA150,Maskless Aligner ,Heidelberg uPG501,Microscope Nikon LV150,Polyimide/SU8 Hood,Spinner Hood,Ultraviolet Flood Exposure System , Inpro Technologies F300S,Vacuum Oven,Acid Hoods,Critical Point Dryer ,Tousimis Automegasamdri 915B, Series C,Ultrasonic and Megasonic Cleaners.

Proper citation: Northwestern University Micro/Nano Fabrication Facility (RRID:SCR_017944) Copy   


https://pathology.med.upenn.edu/research/core-resources/tumor-tissue-biospecimen-bank

Centralized biorepository of human biosamples. TTAB is responsible for the collection, processing, and storage of human blood, fluid, and tissue at the University of Pennsylvania Health System. TTAB has a collection bench within Surgical Pathology Suite at Hospital of University of Pennsylvania (HUP).� Our collection bench sits adjacent to frozen section teams managing clinical sample collection and allowing for tight integration of tissue sample collection with clinical pathology teams.

Proper citation: University of Pennsylvania Perelman School of Medicine Tumor Tissue Biospecimen Bank Core Facility (RRID:SCR_022430) Copy   


https://www.med.upenn.edu/ifi/cytofservicecenter.html

CyTOF�enables multi-parametric high-dimensional single�cell analysis�of more than 40 markers per cell, with�minimal background and compensation�issues.�Core�offers variety of�CyTOF-related services including�reagent distribution, consultation,�antibody conjugation, and data acquisition.�

Proper citation: University of Pennsylvania Perelman School of Medicine IFI CyTOF Service Center Core Facility (RRID:SCR_022410) Copy   


https://pmbb.med.upenn.edu/

BioBank supports researchers by providing centralized access to large number of annotated blood and tissue samples.

Proper citation: University of Pennsylvania Perelman School of Medicine Penn Medicine BioBank Core Facility (RRID:SCR_022415) Copy   


https://www.ohsu.edu/multiscale-microscopy-core

Multiscale Microscopy Core at OHSU is electron microscopy core that provides services and training to academic and corporate users.

Proper citation: Oregon Health and Science University Multiscale Microscopy Core Facility (RRID:SCR_022652) Copy   


https://cgb.indiana.edu

CGB offers range of genomic services, including high-throughput DNA/RNA extraction, library preparation, next-generation sequencing, and bioinformatic analysis.

Proper citation: Indiana University Center for Genomics and Bioinformatics Core Facility (RRID:SCR_017165) Copy   


http://www.scripps.edu/florida/technologies/cbs/index.html

Core provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.

Proper citation: Scripps Research Institute - Florida Cell Based High Throughput Screening Core Facility (RRID:SCR_017832) Copy   


https://physiology.case.edu/media/eq_manuals/eq_manual_beckman_optima-l_series_instruction_manual_ll-im-12ab.pdf

Ultracentrifuge is used for centrifugation of subcellular particles, virus isolations, and high purity plasmid DNA.

Proper citation: Beckman Coulter: L-90K Ultracentrifuge (RRID:SCR_019651) Copy   


https://www.brookhaveninstruments.com/product/bi-200sm-research-goniometer/

Goniometer that is used for macro molecular studies and submicron particle sizing with static and dynamic light scattering. It can be used with neutral density filters, polarizer, analyzer, and reference detector.

Proper citation: Brookhaven Instruments: BI-200SM Research Goniometer (RRID:SCR_019754) Copy   


https://www.brookhaveninstruments.com/product/bi-200sm-research-goniometer/

Goniometer that is used for macro molecular studies and submicron particle sizing with static and dynamic light scattering. It can be used with neutral density filters, polarizer, analyzer, and reference detector.

Proper citation: Brookhaven Instruments BI-200SM Research Goniometer (RRID:SCR_019755) Copy   


https://www.research.chop.edu/flow-cytometry

Core provides access to instrumentation and technical expertise. Offers services, including sample preparation, advanced multi-color analysis, and high-speed cell sorting. Our experienced staff delivers personalized training and project-specific consultations.

Proper citation: Children's Hospital of Philadelphia Flow Cytometry Core Facility (RRID:SCR_009726) Copy   


http://mbcf.dfci.harvard.edu

Core offers services for genomic next-generation sequencing library preparation, sequencing and analysis applications including RNAseq, ChIPseq, ATACseq, CRISPR screening, whole genome methylation profiling, targeted resequencing, single-cell RNAseq, exome sequencing, and more. Performs bioinformatics analysis such as integration of multi-omics datasets or specialized analyses. Genomics core technology platforms include Illumina NovaSeq6000, NextSeq500s, MiSeqs, MiniSeq. High throughput sample preparation is performed on Beckman Coulter Biomek FX and i7 systems. Low throughput samples are prepared by technical staff.

Proper citation: Dana-Farber Cancer Institute Molecular Biology Core Facility (RRID:SCR_009754) Copy   


https://sites.dartmouth.edu/toxmetal/program-resources/trace-element-analysis/

Analysis of elemental composition of biological tissues and fluids by Inductively Coupled Plasma Mass spectrometry. Analysis of Arsenic species in urine and blood by chromatography-ICP-MS. Laser ablation analysis of tissue sections for imaging of elemental distributions.

Proper citation: Dartmouth Trace Element Analysis Core Facility (RRID:SCR_009777) Copy   


https://flow.forsyth.org/

Core offers consulting and support services for detection of different fluorescent parameters simultaneously, RBC contaminated samples, and high throughput analysis using 96 or 384-well plates. Cell sorter allows for collecting cells/particulates of interest, after screening for positively selected markers, downstream applications, and is capable of sorting four separate cell populations simultaneously.

Proper citation: Forsyth Institute Flow Cytometry Core Facility (RRID:SCR_009785) Copy   


https://bioinformatics.forsyth.org/

Core specializes in oral microbial genomics, taxonomy, phylogenetics and the next generation sequence (NGS) data analysis with both in house and cloud high performance computational resource. In addition to supporting funded bioinformatics projects, Bioinformatics Core will also provide computational support to Forsyth and other researchers for processing, analyzing, and interpreting biological data.

Proper citation: Forsyth Institute Bioinformatics Core Facility (RRID:SCR_009783) Copy   


https://www.ohsu.edu/flow-cytometry-core

Core facility that provides the following services: Analytical flow cytometry service, Cell sorting service, Flow cytometry data analysis service, Grant preparation support service, Flow cytometry instrument training, Flow cytometry consultation service. The OHSU Flow Cytometry Shared Resource (FCSR) has operated as a core resource for OHSU Knight Cancer Institute members since 1996 and provides advanced flow cytometry instrumentation, technical expertise and technical services. The FCSR also provides training in data interpretation, experiment design and routine operation to researchers, offering an additional cost-saving option of doing some of the work themselves. Finally, this resource saves valuable investigator time by analyzing specimens and preparing them, if needed.

Proper citation: OHSU Flow Cytometry and Monoclonal Antibody Shared Resource Core Facility (RRID:SCR_009974) Copy   



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