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http://umassmed.edu/umpc/cores/cardiovascular/

Core that provides phenotyping of cardiovascular system in mouse models of metabolic disease and an easily accessible cardiovascular disease model pipeline. It services include 2D and M-mode echocardiography in lightly-anesthetized mice to non-invasively assess cardiac structure and function using state-of-the-art high-frequency, high-resolution in vivo digital imaging platform as well as Transverse Aortic Constriction (TAC) model to investigate pressure-overload hypertrophy, congestive heart failure, and aortic stenosis.

Proper citation: MMPC-University of Massachusetts Medical School Cardiovascular Core (RRID:SCR_015375) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=50

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2025. Core whose mission is to provide analytical tools to investigators to permit determination of the structure of the microbiome in mouse models of disease and assistance in the cultivation of microbes that will permit hypothesis testing in murine models including the germfree animals that are available in the Animal Care Core.

Proper citation: MMPC-University of Michigan Medical School Microbiome Core (RRID:SCR_015378) Copy   

•   Source: SciCrunch Registry

https://medicine.uiowa.edu/genetherapy/research-cores/comparative-pathology-core

Core facility which provides comprehensive necropsy, histology, and pathology services for animal models in order to facilitate translational research in animal models of cystic fibrosis. It also houses instrumentation which allows for high-throughput optimization of immunostaining protocols and has access to morphologic equipment that allow for the scanning of large tissue areas and morphometric quantification of histologic endpoints.

Proper citation: University of Iowa Center for Gene Therapy Comparative Pathology Core (RRID:SCR_015411) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10820/community_id/1418

Core that consists of three subcores: Hormone Assay and Analytical Services, Lipids, Lipoproteins, and Atherosclerosis, and Mouse Pathology. The Hormone Assay and Analytical Services provides analyses that facilitate research in diabetic, cardiovascular, and obese animal models. Lipids and Lipoproteins Subcore provides quantitative and qualitative measurements of plasma and tissue lipids and lipoproteins to researchers who use mice to study atherosclerosis, dyslipidemia, diabetes, obesity, hypertension, and other metabolic diseases. Mouse Pathology services include standard pathology testing in hematology, clinical chemistry, parasitology, microbiology, serology, molecular diagnostics, necropsy, and research histology and pathology expertise and counseling.

Proper citation: MMPC-Vanderbilt University School of Medicine Analytical Resources Core (RRID:SCR_015379) Copy   

•   Source: SciCrunch Registry

http://www.uc.edu/labs/mmpc/select-test/energy-balance.html

Core that specializes in total body/carcass analysis, measurement of oxygen consumption and carbon dioxide production, meal pattern analysis, and feeding mass/bouts, drinking volume, VO2 and VCO2.

Proper citation: MMPC-University of Cincinnati Medical Center Energy Metabolism Food Intake and Body Weight Regulation Core (RRID:SCR_015371) Copy   

•   Source: SciCrunch Registry

http://www.medschool.umaryland.edu/norc/Cores/Molecular-Genetics--Nutrigenomics-MGN-Core/

Core that aims to discover genes and gene-nutrient interactions associated with risk of obesity, diabetes, hypertension, atherogenesis and longevity. Its goal is to understand the molecular, cellular and physiological roles of genes in the etiology of obesity, diabetes, and associated metabolic abnormalities.

Proper citation: Mid-Atlantic Nutrition Obesity Research Center Molecular Genetics and Nutrigenomics Core (RRID:SCR_015459) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd/cores/advanced-analytics

Core facility provides solutions for studying proteins, peptides, and other molecules, including mRNA and cDNA. The Core's immunotechnologies (IT) component provides consultation, ordering, and immunoassay services, and supports a variety of analytes in both traditional ELISA/EIA and xMAP-based multiplex bead assay formats.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Advanced Analytics Core (RRID:SCR_015613) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd/cores/large-animal-core

Core facility that provides consultation and procedural expertise on development on novel models of relevant digestive diseases in large animals.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Large Animal Models Core (RRID:SCR_015619) Copy   

•   Source: SciCrunch Registry

http://sph.unc.edu/norc/nutrigenetics/

Core facility whose services include grant writing assistance and consultation, laboratory analyses, brokerage services, and analytical services.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Nutrigenetics Core (RRID:SCR_015464) Copy   

•   Source: SciCrunch Registry

http://sph.unc.edu/norc/metabolic/

Core whose goals are to encourage and facilitate the use of biomarkers for nutritional epidemiological and intervention studies. It provides access to techniques and equipment to bench scientists, as well as assays for investigators without lab facilities.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Metabolic Molecular Phenotyping Core (RRID:SCR_015463) Copy   

•   Source: SciCrunch Registry

http://mmoc.med.umich.edu/CoreAdministrative.php

Core that provides leadership, infrastructure and resources to promote the integration of basic research technologies into preclinical, clinical and translational research studies, oversee the Investigational Weight Management Clinic, and recruit, train and retain basic, clinical and population-based researchers in the area of nutrition interventions and obesity and related metabolic disorders.

Proper citation: University of Michigan Nutrition and Obesity Research Center Administrative Core (RRID:SCR_015468) Copy   

•   Source: SciCrunch Registry

http://sph.unc.edu/norc/biostatistics/

Core whose services include data management, manuscript development, sample size and power calculations, statistical consultation, and statistical programming for nutrition and/or obesity researchers.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Biostatistics Program (RRID:SCR_015467) Copy   

•   Source: SciCrunch Registry

http://mmoc.med.umich.edu/CoreHumanPhenotyping.php

Core that aims to enhance and expand the research capabilities of investigators performing clinical and translational studies related to nutritional interventions, obesity, or obesity-related disorders in humans. Its services include standardized nutritional assessments and physiological testing of human subjects, researcher assistance in conducting dietary, behavioral, and/or exercise intervention in human subjects, and training in techniques or the assistance in development of new techniques and technologies for the metabolic and neurobehavioral assessment of humans.

Proper citation: University of Michigan Nutrition and Obesity Research Center Human Phenotyping Core (RRID:SCR_015460) Copy   

•   Source: SciCrunch Registry

http://www.jhugicc.org/GIConteCenter/pages/cores/proteomicsCore.html

Core facility that uses mass spectrometry coupled to one (1D) and two (2D) dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are expressed in well characterized protein fractions from the small intestine, colon, kidney, liver and pancreas. Techniques such as difference gel electrophoresis (DIGE), isobaric tag for relative and absolute quantitation (iTRAQ), tandem mass tags (TMT) and stable isotope labeling of amino acids in cell culture (SILAC) as well as non-labeling methods (MudPIT, multi-dimensional protein identification technology) are available for quantifying relative differences in protein expression and post-translational modifications, such as acetylation, glycosylation, phosphorylation, nitrosation, ubiquitination and novel cleavage sites.

Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Proteomics Core (RRID:SCR_015597) Copy   

•   Source: SciCrunch Registry

http://www.norc.uab.edu/corefacilities/physicalactivity

Core that provides physical activity services and consultation for UAB investigators. Services include aerobic fitness tests, supervised resistance training, submaximal ease/economy locomotion tests, and strength and functional tests, with respective measurements taken.

Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Physical Activity Core (RRID:SCR_015474) Copy   

•   Source: SciCrunch Registry

http://www.urology.wisc.edu/research/u54-george-m-obrien-center-for-benign-urology-research/rodent-urinary-function-testing-ruft-core/

Core that designs, validates, and disseminates protocols for rodent urinary function testing. It also provides urinary function testing services, expertise, laboratory space, vivarium, and equipment for complete mouse urinary function testing.

Proper citation: O'Brien Center for Benign Urologic Research at University of Wisconsin-Madision and University of Massachusetts-Boston Rodent Urinary Function Testing Core (RRID:SCR_015477) Copy   

•   Source: SciCrunch Registry

http://www.jhugicc.org/GIConteCenter/pages/cores/imagingCore.html

Core facility that provides state-of-art light microscopy technology to the members of the Hopkins Basic Research Digestive Disease Development Center and to the whole Hopkins scientific community.

Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Image Core (RRID:SCR_015593) Copy   

•   Source: SciCrunch Registry

https://hddc.hms.harvard.edu/bio-repository-and-data-registry-human-material

Core facility that supports basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. It also aims to to forge connections and support collaboration between HDDC Clinical Associates and Members, support a well-organized infrastructure for acquisition and storage of clinical samples, and provide professional support in biostatistics and study design to HDDC members and Clinical Associates.

Proper citation: Harvard Digestive Diseases Center Bio-Repository and Data Registry for Human Material (RRID:SCR_015590) Copy   

•   Source: SciCrunch Registry

http://www.jhugicc.org/GIConteCenter/pages/cores/integratedPhysiology.html

Core facility that provides Center investigators and their laboratories the tools and advice needed to establish and study mouse (including transgenic and knockout) and human (i.e. GI organoids) physiology of GI disease.

Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Integrated Physiology Core (RRID:SCR_015591) Copy   

•   Source: SciCrunch Registry

http://norc.pbrc.edu/animal_core.asp

Core that is comprised of the Animal Models Subcore and Animal Phenotyping Subcore. The former provides expertise and services for design and construction of transgenes, ES cell transfection and screening, pronuclear injection, and cryopreservation. The latter provides expertise and services for metabolism, physical activity, body composition, and behavioral research.

Proper citation: Pennington Biomedical Research Center Nutrition and Obesity Research Center Animal Models and Phenotyping Core (RRID:SCR_015443) Copy   

•   Source: SciCrunch Registry