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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Graph2GO
 
Resource Report
Resource Website
1+ mentions
Graph2GO (RRID:SCR_018726) data analysis software, data processing software, software application, software resource Software tool as graph based representation learning method for protein function prediction. Multi modal graph based representation learning model that can integrate heterogeneous information including multiple types of interaction networks including sequence similarity network and protein-protein interaction network, and protein features including amino acid sequence, sub cellular location and protein domains, to predict protein functions on Gene Ontology. Protein function prediction, graph neural network, attributed network embedding, representation learning, multi-modal model, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Ohio State University College of Medicine; Ohio; USA
Free, Available for download, Freely available SCR_018727, biotools:graph2go https://integrativeomics.shinyapps.io/graph2go/, https://bio.tools/graph2go SCR_018726 2026-09-12 12:59:05 2
IndelFR - Indel Flanking Region Database
 
Resource Report
Resource Website
1+ mentions
IndelFR - Indel Flanking Region Database (RRID:SCR_006050) IndelFR data or information resource, database THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. Indel Flanking Region Database is an online resource for indels and the flanking regions of proteins in SCOP superfamilies, including amino acid sequences, lengths, locations, secondary structure constitutions, hydrophilicity / hydrophobicity, domain information, 3D structures and so on. It aims at providing a comprehensive dataset for analyzing the qualities of amino acid insertion/deletions(indels), substitutions and the relationship between them. The indels were obtained through the pairwise alignment of homologous structures in SCOP superfamilies. The IndelFR database contains 2,925,017 indels with flanking regions extracted from 373,402 structural alignment pairs of 12,573 non-redundant domains from 1053 superfamilies. IndelFR has already been used for molecular evolution studies and may help to promote future functional studies of indels and their flanking regions. indel, flanking region, protein, structural domain, domain, protein superfamily, protein structure, insertion/deletion, insertion, deletion, protein sequence, sequence, structure, protein domain, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: SCOP: Structural Classification of Proteins
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Shandong University; Shandong; China
Independent Innovation Foundation of Shandong University 2009JC006;
National Natural Science Foundation of China 30970092;
National Natural Science Foundation of China 61070017;
Scientific Research Reward Fund for excellent Young and Middle-Aged scientists in Shandong Province 20090451326
PMID:22127860 THIS RESOURCE IS NO LONGER IN SERVICE biotools:indelfr, nlx_151448 https://bio.tools/indelfr SCR_006050 IndelFR: Indel Flanking Region Database, Indel Flanking Region Database 2026-09-12 01:01:40 2
ProfCom - Profiling of complex functionality
 
Resource Report
Resource Website
1+ mentions
ProfCom - Profiling of complex functionality (RRID:SCR_005797) ProfCom analysis service resource, data analysis service, production service resource, service resource Profiling of Complex Functionality (ProfCom) is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of complex function. A complex function is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. Platform: Online tool gene, function, profile, gene ontology, complex function, statistical analysis, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: Institute of Bioinformatics and Systems Biology; Neuherberg; Germany
DFG PMID:16959266 Free for academic use biotools:profcom, nlx_149276 https://bio.tools/profcom SCR_005797 Profiling of Complex Functionality, Profiling of Complex Functionality (ProfCom) 2026-09-12 01:01:39 4
SerbGO
 
Resource Report
Resource Website
SerbGO (RRID:SCR_005798) SerbGO analysis service resource, data analysis service, production service resource, service resource SerbGO is a web-based tool intended to assist researchers determine which microarray tools for gene expression analysis which make use of the GO ontologies are best suited to their projects. SerbGO is a bidirectional application. The user can ask for some features by checking on the Query Form to get the appropriate tools for their interests. The user can also compare tools to check which features are implemented in each one. Platform: Online tool microarray, gene expression, statistical analysis, gene ontology, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Barcelona; Barcelona; Spain
PMID:18480123 Free for academic use nlx_149286, biotools:serbgo https://bio.tools/serbgo SCR_005798 SerbGO - Searching the best GO Tool 2026-09-12 01:01:39 0
SNPedia
 
Resource Report
Resource Website
50+ mentions
SNPedia (RRID:SCR_006125) SNPedia data or information resource, database Wiki investigating human genetics including information about the effects of variations in DNA, citing peer-reviewed scientific publications. It is used by Promethease to analyze and help explain your DNA. It is based on a wiki model in order to foster communication about genetic variation and to allow interested community members to help it evolve to become ever more relevant. As the cost of genotyping (and especially of fully determining your own genomic sequence) continues to drop, we''''ll all want to know more - a lot more - about the meaning of these DNA variations and SNPedia will be here to help. SNPedia has been launched to help realize the potential of the Human Genome Project to connect to our daily lives and well-being. For more information see the Wikipedia page, http://en.wikipedia.org/wiki/SNPedia * Download URL: http://www.SNPedia.com/index.php/Bulk * Web Service URL: http://bots.SNPedia.com/api.php dna, genetics, gene, genome, genoset, genotype, medicine, medical condition, genetic variation, dna, genetic variation, genomics, single nucleotide polymorphism, medical association, phenotypic association, genealogical association, variation, genome annotation, phenotype, web service, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
PMID:22140107 Creative Commons Attribution-NonCommercial-ShareAlike License, v3 biotools:snpedia, grid.465250.0, nlx_151604 https://ror.org/0253rdk33, https://bio.tools/snpedia SCR_006125 2026-09-12 01:01:41 64
RNA CoSSMos
 
Resource Report
Resource Website
1+ mentions
RNA CoSSMos (RRID:SCR_006120) RNA CoSSMos data or information resource, database Database to search through the nucleic acid structures from the Protein Data Bank and examine structural motifs, including (a)symmetric internal loops, bulge loops, and hairpin loops. They have compiled over 2,000 three-dimensional structures, which can now be searched using different parameters, including PDB information, experimental technique, sequence, and motif type. RNA secondary structure is important for designing therapeutics, understanding protein-RNA binding and predicting tertiary structure of RNA. Several databases and downloadable programs exist that specialize in the three-dimensional (3D) structure of RNA, but none focus specifically on secondary structural motifs such as internal, bulge and hairpin loops. To create the RNA CoSSMos database, 2156 Protein Data Bank (PDB) files were searched for internal, bulge and hairpin loops, and each loop''''s structural information, including sugar pucker, glycosidic linkage, hydrogen bonding patterns and stacking interactions, was included in the database. False positives were defined, identified and reclassified or omitted from the database to ensure the most accurate results possible. Users can search via general PDB information, experimental parameters, sequence and specific motif and by specific structural parameters in the subquery page after the initial search. Returned results for each search can be viewed individually or a complete set can be downloaded into a spreadsheet to allow for easy comparison. The RNA CoSSMos database is updated weekly. secondary structure motif, rna, three-dimensional structure, internal loop, bulge loop, hairpin loop, motif, nucleic acid, structure, secondary structure, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Saint Louis University; Missouri; USA
NIGMS 1R15GM085699-01A1 PMID:22127861 Freely accessible, Acknowledgement requested nlx_151597, biotools:rna_cossmos https://bio.tools/rna_cossmos SCR_006120 Znosko Lab RNA Characterization of Secondary Structure Motifs (RNA CoSSMos) database, Znosko Lab CoSSMos Database, RNA Characterization of Secondary Structure Motifs (RNA CoSSMos), RNA CoSSMos Database, RNA CoSSMos - Characterization of Secondary Structure Motifs, RNA Characterization of Secondary Structure Motifs 2026-09-12 01:01:41 1
GoPubMed
 
Resource Report
Resource Website
10+ mentions
GoPubMed (RRID:SCR_005823) GoPubMed data or information resource, database, service resource A web server which allows users to explore PubMed search results with the Gene Ontology, a hierarchically structured vocabulary for molecular biology. GoPubMed submits a user''''s keywords to PubMed, retrieves the abstracts, detects Gene Ontology terms in the abstracts, displays the subset of Gene Ontology relevant to the original query, and allows the user to browse through the ontology displaying associated papers and their GO annotation. Platform: Online tool other analysis, literature curation and exploration, gene ontology, pubmed, literature, bio.tools is listed by: OMICtools
is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: PubMed
has parent organization: Biotechnology Center of the TU Dresden
European Union IST-2004-506779 PMID:15980585 Free for academic use biotools:gopubmed, nlx_149328, OMICS_01183 https://bio.tools/gopubmed SCR_005823 2026-09-12 01:01:39 29
Expression Profiler
 
Resource Report
Resource Website
1+ mentions
Expression Profiler (RRID:SCR_005821) Expression Profiler analysis service resource, data analysis service, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. The EP:GO browser is built into EBI's Expression Profiler, a set of tools for clustering, analysis and visualization of gene expression and other genomic data. With it, you can search for GO terms and identify gene associations for a node, with or without associated subnodes, for the organism of your choice. other analysis, cluster, analysis, visualization, gene expression, genomic, gene ontology, gene association, microarray, protein-protein interaction, gene, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: European Bioinformatics Institute
European Union ;
Wellcome Trust ;
Estonian Science Foundation 5724;
Estonian Science Foundation 5722
PMID:15215431 THIS RESOURCE IS NO LONGER IN SERVICE biotools:expression_profiler, nlx_149323 https://bio.tools/expression_profiler SCR_005821 Expression Profiler at the EBI 2026-09-12 01:01:39 6
NRG-CING
 
Resource Report
Resource Website
1+ mentions
NRG-CING (RRID:SCR_006079) NRG-CING data or information resource, database NRG-CING presents a complete validation report for all 9,000+ wwPDB NMR entries including remediated experimental data such as chemical shifts from BMRB and restraints from NRG . These CING reports are compiled from internal analyses and those by CCPN, DSSP, PROCHECK-NMR/Aqua, ShiftX, Talos+, Vasco, Wattos, and WHAT_CHECK. The NRG-CING website is a collection of CING reports that has been pre-calculated for all PDB files solved by NMR. (See website for more information on CING.) In case the underlying experimental data is available, these have been cleaned up and made syntactically and semantically correct and homogeneous. For many macromolecular NMR ensembles from the Protein Data Bank (PDB) the experiment-based restraint lists used in the structure calculation are accessible, while other experimental data, mainly chemical shift values, are often available from the BioMagResBank. Assessment of the quality of the structural result is paramount to their usage and a combined, integrated repository of both input data and structural results greatly facilitates such an analysis. In addition, the accuracy and precision of the coordinates in these macromolecular NMR ensembles can be improved by recalculations using the available experimental data and present-day software with improved protocols and force fields. Such efforts, however, generally fail on over half of all deposited structures due to the syntactic and semantic heterogeneity of the data and the wide variety of formats used for their deposition. We have combined the cleaned-up restraints information from the NMR Restraints Grid (NRG) database with available chemical shifts from the BioMagResBank in the weekly updated NRG-CING database. Eleven programs, in addition to CING itself, have been included in the NRG-CING production pipeline to arrive at validation reports that list for each entry the potential inconsistencies between the coordinates and the available restraint and chemical shift data. The longitudinal validation of this data yielded a set of indicators that can be used to judge the quality of every macromolecular structure solved with NMR. The cleaned up NMR experimental datasets and the validation reports are freely available. macromolecular structure, nmr, macromolecule, restraint, chemical shift, validation report, validation, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Worldwide Protein Data Bank (wwPDB)
is related to: NMR Restraints Grid
is related to: Biological Magnetic Resonance Data Bank (BMRB)
has parent organization: Radboud University; Nijmegen; The Netherlands
Netherlands Organization for Scientific Research (NWO) 700.55.443;
Netherlands Bioinformatics Centre (NBIC) ;
EU FP6 LSHG-CT-2005-018988;
EU FP6 LHSG-CT-2004-512092;
EU FP7 261572;
Brussels Institute for Research and Innovation BB2B 2010-1-12;
NLM LM05799
PMID:22139937 Free nlx_151486, biotools:nrg-cing https://bio.tools/nrg-cing SCR_006079 2026-09-12 01:01:40 1
ProPortal
 
Resource Report
Resource Website
1+ mentions
ProPortal (RRID:SCR_006112) ProPortal data or information resource, database ProPortal is a database containing genomic, metagenomic, transcriptomic and field data for the marine cyanobacterium Prochlorococcus. Our goal is to provide a source of cross-referenced data across multiple scales of biological organization--from the genome to the ecosystem--embracing the full diversity of ecotypic variation within this microbial taxon, its sister group, Synechococcus and phage that infect them. The site currently contains the genomes of 13 Prochlorococcus strains, 11 Synechococcus strains and 28 cyanophage strains that infect one or both groups. Cyanobacterial and cyanophage genes are clustered into orthologous groups that can be accessed by keyword search or through a genome browser. Users can also identify orthologous gene clusters shared by cyanobacterial and cyanophage genomes. Gene expression data for Prochlorococcus ecotypes MED4 and MIT9313 allow users to identify genes that are up or downregulated in response to environmental stressors. In addition, the transcriptome in synchronized cells grown on a 24-h light-dark cycle reveals the choreography of gene expression in cells in a ''natural'' state. Metagenomic sequences from the Global Ocean Survey from Prochlorococcus, Synechococcus and phage genomes are archived so users can examine the differences between populations from diverse habitats. Finally, an example of cyanobacterial population data from the field is included. genomic, metagenomic, transcriptomic, field data, marine cyanobacterium, genome, ecosystem, ecotypic variation, microbial taxon, phage, genome, gene, orthologous gene cluster, cyanobacteria, cyanophage genome, population dynamics, microarray, metagenome, protein, cyanophage, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
NSF OCE-0425602;
NSF EF0424599;
DOE DE-FG02-02ER63445;
DOE DE-FG02-08ER64516;
DOE DE-FG02-07ER64506;
Gordon and Betty Moore Foundation award letter 495.01
PMID:22102570 Public nlx_151586, biotools:proportal https://bio.tools/proportal SCR_006112 Prochlorococcus Portal 2026-09-12 01:01:41 9
UniParc
 
Resource Report
Resource Website
50+ mentions
UniParc (RRID:SCR_005818) data or information resource, database Database that contains publicly available protein sequences with stable and unique identifiers (UPI) which are never removed, changed or reassigned. UniParc tracks sequence changes in the source databases and archives the history of all changes. Information other than protein sequence must be retrieved from the UniParc source databases using the database cross-references. protein sequence, database, public protein sequence, gold standard, upi, unique protein identifier, identifier, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: UniProt DAS
is related to: WormBase
is related to: FlyBase
is related to: Ensembl
is related to: RefSeq
has parent organization: UniProt
Public, Entries are available for download SCR_004769, nif-0000-03610, r3d100011519, biotools:uniparc, nlx_76940 https://bio.tools/uniparc, https://doi.org/10.17616/R3X33B SCR_005818 UniProt Archive 2026-09-12 01:01:39 98
Dr.VIS - Human Disease-Related Viral Integration Sites
 
Resource Report
Resource Website
1+ mentions
Dr.VIS - Human Disease-Related Viral Integration Sites (RRID:SCR_005965) Dr.VIS, Dr. VIS data or information resource, database Dr.VIS collects and locates human disease-related viral integration sites. So far, about 600 sites covering 5 virus organisms and 11 human diseases are available. Integration sites in Dr.VIS are located against chromosome, cytoband, gene and refseq position as specific as possible. Viral-cellular junction sequences are extracted from papers and nucleotide databases, and linked to corresponding integration sites Graphic views summarizing distribution of viral integration sites are generated according to chromosome maps. Dr.VIS is built with a hope to facilitate research of human diseases and viruses. Dr.VIS provides curated knowledge of integration sites from chromosome region narrow to genomic position, as well as junction sequences if available. Dr.VIS is an open resource for free. disease, virus, viral integration, viral integration site, integration site, malignant disease, chromosome region, genomic position, viral-host junction sequence, junction sequence, oncogene, chromosome, catalog, graphic interface, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Tongji University; Shanghai; China
State Key Basic Research Program 973 2011CB910204;
National Natural Science Foundation of China ;
Major State Basic Research Development Program ;
863 Hi-Tech Program of China ;
National Key Technology R&D Program in the 11th Five Year Plan of China ;
Major State Basic Research Development Program of China
PMID:22135288 Open - Free to browse and download data in Dr.VIS. nlx_151323, biotools:dr.vis http://www.scbit.org/dbmi/drvis, https://bio.tools/dr.vis SCR_005965 Dr. VIS - Database of Human Disease-related Viral Integration Sites, Database of Human Disease-related Viral Integration Sites 2026-09-12 01:01:40 1
FunTree
 
Resource Report
Resource Website
1+ mentions
FunTree (RRID:SCR_006014) FunTree data or information resource, database FunTree provides a range of data resources to detect the evolution of enzyme function within distant structurally related clusters within domain super families as determined by CATH. To access the resource enter a specific CATH superfamily code or search for a structure / sequence / function (either via a EC code or KEGG ligand / reaction ID, PDB ID or UniProtKB ID). Or browse the resource via superfamily / function / structure / metabolites & reactions via the menu on the left panel. FunTree is a new resource that brings together sequence, structure, phylogenetic, chemical and mechanistic information for structurally defined enzyme superfamilies. Gathering together this range of data into a single resource allows the investigation of how novel enzyme functions have evolved within a structurally defined superfamily as well as providing a means to analyse trends across many superfamilies. This is done not only within the context of an enzyme''''s sequence and structure but also the relationships of their reactions. Developed in tandem with the CATH database, it currently comprises 276 superfamilies covering 1800 (70%) of sequence assigned enzyme reactions. Central to the resource are phylogenetic trees generated from structurally informed multiple sequence alignments using both domain structural alignments supplemented with domain sequences and whole sequence alignments based on commonality of multi-domain architectures. These trees are decorated with functional annotations such as metabolite similarity as well as annotations from manually curated resources such the catalytic site atlas and MACiE for enzyme mechanisms. enzyme function, enzyme superfamily, enzyme, sequence, structure, phylogenetic, chemical, mechanistic, functional annotation, superfamily, gold standard, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: CATH: Protein Structure Classification
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: KEGG
is related to: UniProtKB
has parent organization: European Bioinformatics Institute
European Molecular Biology Laboratory; Heidelberg; Germany ;
BBSRC ;
Wellcome Trust 081989/Z/07/A;
DOE contract DE-AC02-06CH11357
PMID:22006843 Free biotools:funtree, nlx_151402 https://bio.tools/funtree SCR_006014 2026-09-12 01:01:40 4
DBETH - Database for Bacterial ExoToxins for Humans
 
Resource Report
Resource Website
1+ mentions
DBETH - Database for Bacterial ExoToxins for Humans (RRID:SCR_005908) DBETH data or information resource, database Database of Bacterial ExoToxins for Human is a database of sequences, structures, interaction networks and analytical results for 229 exotoxins, from 26 different human pathogenic bacterial genus. All toxins are classified into 24 different Toxin classes. The aim of DBETH is to provide a comprehensive database for human pathogenic bacterial exotoxins. DBETH also provides a platform to its users to identify potential exotoxin like sequences through Homology based as well as Non-homology based methods. In homology based approach the users can identify potential exotoxin like sequences either running BLASTp against the toxin sequences or by running HMMER against toxin domains identified by DBETH from human pathogenic bacterial exotoxins. In Non-homology based part DBETH uses a machine learning approach to identify potential exotoxins (Toxin Prediction by Support Vector Machine based approach). sequence, structure, interaction network, human, pathogen, bacterial genus, toxin, bacteria, exotoxin, homology, homolog, structure, sequence, domain, prediction, mechanism, activity, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: CSIR - Indian Institute of Chemical Biology; Kolkata; India
Council of Scientific and Industrial Research; New Delhi; India PMID:22102573 nlx_149481, biotools:dbeth https://bio.tools/dbeth SCR_005908 Database for Bacterial ExoToxins for Humans 2026-09-12 01:01:40 2
VirusMINT
 
Resource Report
Resource Website
10+ mentions
VirusMINT (RRID:SCR_005987) VirusMINT data or information resource, database A virus protein interactions database that collects and annotates all the interactions between human and viral proteins and integrates this information in the human protein interaction network. It uses the PSI-MI standard and is fully integrated with the MINT database. You can search for any viral or human protein by entering either common names or database identifiers or display a complete viral interactome. protein interaction, virus, protein, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: PSI-MI
is related to: VirHostNet: Virus-Host Network
is related to: MINT
has parent organization: University of Rome Tor Vergata; Rome; Italy
Papilloma virus, Human immunodeficiency virus, Epstein-Barr virus, Hepatitis B virus, Hepatitis C virus, Herpes virus, Simian virus 40 PMID:18974184 nif-0000-03636, OMICS_01909, biotools:virusmint, r3d100010685 https://bio.tools/virusmint, https://doi.org/10.17616/R3F890 SCR_005987 2026-09-12 01:01:40 18
GOEAST - Gene Ontology Enrichment Analysis Software Toolkit
 
Resource Report
Resource Website
10+ mentions
GOEAST - Gene Ontology Enrichment Analysis Software Toolkit (RRID:SCR_006580) GOEAST analysis service resource, data analysis service, production service resource, service resource Gene Ontology Enrichment Analysis Software Toolkit (GOEAST) is a web based software toolkit providing easy to use, visualizable, comprehensive and unbiased Gene Ontology (GO) analysis for high-throughput experimental results, especially for results from microarray hybridization experiments. The main function of GOEAST is to identify significantly enriched GO terms among give lists of genes using accurate statistical methods. Compared with available GO analysis tools, GOEAST has the following unique features: * GOEAST supports analysis for data from various resources, such as expression data obtained using Affymetrix, illumina, Agilent or customized microarray platforms. GOEAST also supports non-microarray based experimental data. The web-based feature makes GOEAST very user friendly; users only have to provide a list of genes in correct formats. * GOEAST provides visualizable analysis results, by generating graphs exhibiting enriched GO terms as well as their relationships in the whole GO hierarchy. * Note that GOEAST generates separate graph for each of the three GO categories, namely biological process, molecular function and cellular component. * GOEAST allows comparison of results from multiple experiments (see Multi-GOEAST tool). The displayed color of each GO term node in graphs generated by Multi-GOEAST is the combination of different colors used in individual GOEAST analysis. Platform: Online tool statistical analysis, gene ontology, high-throughput, microarray, hybridization, gene, visualization, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: Chinese Academy of Sciences; Beijing; China
National Natural Science Foundation of China 30725014;
National Natural Science Foundation of China 90612019;
Ministry of Science and Technology of China 2007CB946901;
Chinese Academy of Sciences KSCX2-YW-R-134;
Chinese Academy of Sciences KSCX2-YW-N-024
PMID:18487275 Free for academic use biotools:goeast, nlx_149248 https://bio.tools/goeast SCR_006580 Gene Ontology Enrichment Analysis Software Toolkit, Gene Ontology Enrichment Analysis Software Toolkit (GOEAST) 2026-09-12 01:01:43 40
PRED-TMBB
 
Resource Report
Resource Website
50+ mentions
PRED-TMBB (RRID:SCR_006190) PRED-TMBB analysis service resource, data analysis service, production service resource, service resource A web tool, based on a Hidden Markov Model, capable of predicting the transmembrane beta-strands of the gram-negative bacteria outer membrane proteins, and of discriminating such proteins from water-soluble ones when screening large datasets. The model is trained in a discriminative manner, aiming at maximizing the probability of the correct prediction rather than the likelihood of the sequences. The training is performed on a non-redundant database consisting of 16 outer membrane proteins (OMP''s) with their structures known at atomic resolution. We show that we can achieve predictions at least as good comparing with other existing methods, using as input only the amino-acid sequence, without the need of evolutionary information included in multiple alignments. The method is also powerful when used for discrimination purposes, as it can discriminate with a high accuracy the outer membrane proteins from water soluble in large datasets, making it a quite reliable solution for screening entire genomes. This web-server can help you run a discriminating process on any amino-acid sequence and thereafter localize the transmembrane strands and find the topology of the loops. protein, hidden markov model, prediction, membrane protein, beta-barrel outer membrane protein, gram-negative bacteria, topology, outer membrane protein, beta-barrel protein, probability, transmembrane strand, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: University of Athens Biophysics and Bioinformatics Laboratory
Greek Ministry of National Education and Religious Affairs PMID:15215419
PMID:15070403
Acknowledgement requested biotools:pred-tmbb, nlx_151734 https://bio.tools/pred-tmbb SCR_006190 PRED-TMBB: A Hidden Markov Model method capable of predicting and discriminating beta-barrel outer membrane proteins 2026-09-12 01:01:41 58
mitopred
 
Resource Report
Resource Website
1+ mentions
mitopred (RRID:SCR_006135) MITOPRED analysis service resource, data analysis service, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. It predicts nuclear-encoded mitochondrial proteins from all eukaryotic species including plants. Prediction is based on the occurrence patterns of Pfam domains (version 16.0) in different cellular locations, amino acid composition and pI value differences between mitochondrial and non-mitochondrial locations. Additionally, you may download MITOPRED predictions for complete proteomes. Re-calculated predictions are instantly accessible for proteomes of Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila, Homo sapiens, Mus musculus and Arabidopsis species as well as all the eukaryotic sequences in the Swiss-Prot and TrEMBL databases. Queries, at different confidence levels, can be made through four distinct options: (i) entering Swiss-Prot/TrEMBL accession numbers; (ii) uploading a local file with such accession numbers; (iii) entering protein sequences; (iv) uploading a local file containing protein sequences in FASTA format. The Mitopred algorithm works based on the differences in the Pfam domain occurrence patters and amino acid composition differences in different cellular compartments. Location specific Pfam domains have been determined from the entire eukaryotic set of Swissprot database. Similarly, differences in the amino acid composition between mitochondrial and non-mitochondrial sequences were pre-calculated. This information is used to calculate location-specific amino acid weights that are used to calculate amino acid score. Similarly, pI average values of the N-terminal 25 residues in different cellular location were also determined. This knowledge-base is accessed by the program during execution. yeast, c. elegans, drosophila, mouse, human, arabidopsis, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University at Albany; New York; USA
THIS RESOURCE IS NO LONGER IN SERVICE biotools:mitopred, nif-0000-03956, BioTools:mitopred https://bio.tools/mitopred, https://bio.tools/mitopred, https://bio.tools/mitopred SCR_006135 A genome-scale method for predicting mitochondrial proteins 2026-09-12 01:01:41 7
GeneTrail
 
Resource Report
Resource Website
100+ mentions
GeneTrail (RRID:SCR_006250) GeneTrail analysis service resource, data analysis service, production service resource, service resource A web-based application that analyzes gene sets for statistically significant accumulations of genes that belong to some functional category. Considered category types are: KEGG Pathways, TRANSPATH Pathways, TRANSFAC Transcription Factor, GeneOntology Categories, Genomic Localization, Protein-Protein Interactions, Coiled-coil domains, Granzyme-B clevage sites, and ELR/RGD motifs. The web server provides two statistical approaches, "Over-Representation Analysis" (ORA) comparing a reference set of genes to a test set, and "Gene Set Enrichment Analysis" (GSEA) scoring sorted lists of genes., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. pathway, microarray, enrichment, genomic, proteomic, function, transcription factor, genomic localization, protein-protein interaction, coiled-coil domain, granzyme-b clevage site, motif, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: KEGG
is related to: TRANSPATH
is related to: TRANSFAC
is related to: Gene Ontology
has parent organization: Saarland University; Saarbrucken; Germany
PMID:17526521 THIS RESOURCE IS NO LONGER IN SERVICE biotools:genetrail, OMICS_02236 https://bio.tools/genetrail SCR_006250 2026-09-12 01:01:42 114
Magic
 
Resource Report
Resource Website
500+ mentions
Magic (RRID:SCR_006406) MAGIC data or information resource, database, service resource Web based interface for exploring and analyzing a comprehensive maize-specific cross-platform expression compendium. This compendium was constructed by collecting, homogenizing and formally annotating publicly available microarrays from Gene Expression Omnibus (GEO), and ArrayExpress. gene expression, microarray, development stage, annotation, line, perturbation, gene, contrast, pathway, locus tag, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Expression Omnibus
is related to: ArrayExpress
is related to: Plant Ontology
is related to: Gene Ontology
has parent organization: Ghent University; Ghent; Belgium
PMID:24407224 biotools:magic, OMICS_02206 https://bio.tools/magic SCR_006406 MAGIC - MAize Gene expressIon Compendium, MAize Gene expressIon Compendium 2026-09-12 01:01:42 709

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