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https://biotech.rpi.edu/core-facilities/proteomics

Facility provides mass spectrometry-based analytical support.Houses multiple mass spectrometry platforms with complementary ionization capabilities, including EI, APCI, ESI, and MALDI, enabling qualitative and quantitative analysis of diverse sample types across a range of volatility, polarity, and molecular weight. Several systems are coupled with chromatographic separation platforms, allowing complex mixtures to be separated prior to mass spectrometric analysis. Supports research in areas including proteomics, small-molecule analysis, carbohydrate and glycosaminoglycan-related analysis, metabolomics-oriented method development, and drug-discovery-related projects.Particular strength of the Core is the analysis of complex biomolecules, including proteins, peptides, carbohydrates, and heparin/glycosaminoglycan-related samples. The Core works closely with investigators to evaluate feasibility, develop appropriate workflows, and interpret mass spectrometry data in the context of each project.

Proper citation: Rensselaer Polytechnic Institute RPI-Proteomics Core Facility (RRID:SCR_028377) Copy   

•   Source: SciCrunch Registry

https://chop.ilab.agilent.com/sc/5558/chop-engineered-cell-therapy-core/?tab=about

Core provides services and expertise to advance chimeric antigen receptor (CAR) T or other cell therapy research.Services include guidance in the design, construction, and selection of CARs and other cell therapies against a multitude of targets and diseases. Core offers small-scale lentivirus production and small-scale T cell transduction and expansion for experimental purposes.

Proper citation: Children's Hospital of Philadelphia CHOP Engineered Cell Therapy Core Facility (RRID:SCR_028415) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/biostatistics-statistical-genomics

Core offers services in design, oversight, implementation, analysis, publication, and reporting of scientific studies including articulating study objectives and hypotheses, grant writing, conceiving appropriate cost-effective designs and models for achievement of study objectives, monitoring interim and final analyses, and co-authoring abstracts and manuscripts.

Proper citation: Roswell Park Comprehensive Cancer Center Biostatistics and Statistical Genomics Shared Resource BSGSR Core Facility (RRID:SCR_028371) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/gmp

Core provides clean rooms, cell therapy equipment, manufacturing know-how, capabilities and comprehensive suite of quality assurance and control procedures.

Proper citation: Roswell Park Comprehensive Cancer Center GMP Engineering and Cell Manufacturing Core Facility (RRID:SCR_028373) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/chop-microbiome-center

Core is sequencing and analytical resource of the PennCHOP Microbiome Program, providing end-to-end solutions for microbiome research. Sequencing lab offers expertise in next-generation DNA sequencing for microbiome studies, working with customers to provide optimized workflows and protocols customized for each study. Provides expertise in bioinformatics and statistical analysis of microbiome data. Develops an analytical plan specific to your project and can integrate microbiome data with other data sources, such as metabolomics or dietary intake information.

Proper citation: Children's Hospital of Philadelphia CHOP Microbiome Center Core Facility (RRID:SCR_028408) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/comparative-oncology

Core offers services for preclinical models including barrier facilities with fully automated environmental controls for the housing of research models. Specialized husbandry with trained staff who perform all manipulations inside Biosafety cabinets for maintenance of a pathogen-free environment for models held in micro isolation (MI) housing systems. In addition to housing pre-clinical models in state-of-the-art facilities, COSR provides Specialized Surgical Services and procedural training, consultation in experimental design, irradiation services, in-house hematological testing, genotyping services, design and conduct of pre-clinical toxicological studies.

Proper citation: Roswell Park Comprehensive Cancer Center Comparative Oncology Shared Resource COSR Core Facility (RRID:SCR_028389) Copy   

•   Source: SciCrunch Registry

https://research.manchester.ac.uk/en/equipments/biomolecular-nmr-facility/

Core provides advanced NMR spectroscopy for researching the atomic-level structure, dynamics, and interactions of biological macromolecules. It supports structural biology, biocatalysis, and drug discovery by analyzing proteins, DNA, RNA, and carbohydrates. Includes 800MHz NMR spectrometer with H/F-C-N Cryoprobe.

Proper citation: University of Manchester Biomolecular NMR Core Facility (RRID:SCR_028357) Copy   

•   Source: SciCrunch Registry

https://www.bruker.com/en/products-and-solutions/infrared-and-raman/ft-ir-research-spectrometers/invenio-ft-ir-spectrometer.html

Bruker Invenio S is an entry-level FT-IR spectrometer designed for routine productivity and basic research and development. Analytical instrument that identifies chemical compounds and molecular structures by measuring how samples absorb infrared light. Offers upgradable Invenio platform featuring the Transit channel and MultiTect technology.

Proper citation: Bruker: Invenio S FT-IR Spectrometer (RRID:SCR_028359) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/cag-genotyping-core

Core is equipped with liquid handling technology and experienced staff members. Offers both standard and custom Illumina array project design. With the capacity to process >2300 samples/week and generate >480 million genotypes per day, the genotyping core fully integrates with our Biorepository and Bioinformatics group, offering the collaborator the opportunity for a seamless experience from DNA extraction to data release.

Proper citation: Children's Hospital of Philadelphia CHOP CAG Genotyping Core Facility (RRID:SCR_028400) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/single-cell-technology-core

Core offers services and access to single-cell, spatial and in situ technologies. Provides instruments, experienced research assistants and bioinformaticians to experimental and computational support. Services include 10x Genomics single cell assays, 10x Genomics Visium CytAssist and Visium HD spatial transcriptomics, 10x Genomics Xenium in situ spatial transcriptomics, Vizgen MERSCOPE in situ spatial transcriptomics, NanoString GeoMx Digital Spatial Profiler RNA and protein assays.

Proper citation: Children's Hospital of Philadelphia CHOP Single Cell Technology Core Facility (RRID:SCR_028401) Copy   

•   Source: SciCrunch Registry

http://NIC.botany.wisc.edu

Core provides services in confocal microscopy (CLSM, including FRET, ion imaging, and colocalization), scanning electron microscopy (SEM, including ESEM for wet samples), SEM prep instrumentation (critical point dryer and sputter coater), epifluorescence microscopy and polarizing microscopy.

Proper citation: University of Wisconsin Madison Newcomb Imaging Center NIC Core Facility (RRID:SCR_028453) Copy   

•   Source: SciCrunch Registry

https://mskcc.sharepoint.com/sites/pub-CoreFacilities/SitePages/Clinical-Grade-Production.aspx?e=nYjsKv

cGMP facility responsible for the bulk product manufacture, purification, and characterization of clinical-grade materials. Offers vialing of sterile investigational products such as peptides, proteins, carbohydrates, and adjuvants. Service also conducts lot release tests which are required for products release for preclinical and investigational use either in-house or with validated contract vendors.

Proper citation: Memorial Sloan Kettering Cancer Center MSKCC Clinical Grade Production Core Facility (RRID:SCR_028454) Copy   

•   Source: SciCrunch Registry

https://www.ouhealth.com/stephenson-cancer-center/cancer-research/cancer-shared-resources-services/tissue-pathology-biospecimen-shared-resource/

Core provides tissue processing, histology and staining services. Services include embedding, sectioning, histochemical staining of mounted slides, immunohistochemical (IHC) staining for paraffin embedded and frozen tissues, immunocytochemical (ICC) staining for cultured cells (as tissue sections or cytospin slides), evaluation of new antibodies for IHC staining, enzyme histochemistry and special staining.Provides defined analyses including RNA / DNA preparation, reverse transcription and cDNA synthesis from total RNA, construction, staining and analysis of tissue microarrays, and construction and analysis of reverse proteomics array from user-defined biospecimens.Core is flexible to accommodate the development of new techniques and expanding its services based on the research requirements of SCC members and other investigators.

Proper citation: University of Oklahoma Health Sciences Center Tissue Pathology and Biospecimen Core Facility (RRID:SCR_028452) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/chop-high-throughput-sequencing-core

Core is service facility providing instrumentation, library preparation, and sequencing services to CHOP, UPenn, and external investigators in genomic, epigenomic and transcriptomic studies.

Proper citation: Children's Hospital of Philadelphia CHOP High Throughput Sequencing Core Facility (RRID:SCR_028398) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/about/research-integrity.html

Core enables and promotes responsible research practices to generate trustworthy data, and to safeguard research data. The service is comprised of 4 pillars; governance, good research practice support, stewardship and knowledge exchange.

Proper citation: Cancer Research UK Scotland Institute Research Integrity Service Core Facility (RRID:SCR_028431) Copy   

•   Source: SciCrunch Registry

https://uwhistologyandimaging.org/

Core provides histology, immunohistochemistry, imaging, quantitative image analysis, and pathology consultation services. Offers experience, expertise and instrumentation across all platforms. Through the partnership with the Comparative Pathology Program (CPP), we have board certifies veterinary pathologists on staff who are available for research consultation and collaboration.

Proper citation: University of Washington Histology and Imaging Core Facility (RRID:SCR_028435) Copy   

•   Source: SciCrunch Registry

https://sites.google.com/fieldmuseum.org/research/laboratories/core-laboratories/sem

Interdepartmental core facility for scanning electron microscope imaging and elemental analysis of objects. Provides Hitachi SU7000 field emission scanning electron microscope, an Oxford Ultim Max 170 infinity EDS detector with BEX (backscatter electron and X-ray imaging detector), a Leica EM Ace600 sputter coater and a Hitachi IM4000II ion milling system.

Proper citation: Field Museum of Natural History Scanning Electron Microscopy Laboratory Core Facility (RRID:SCR_028394) Copy   

•   Source: SciCrunch Registry

https://institutducerveau.org/plateforme-dexploration-preclinique-phenoparc

Core provides infrastructure (A1 and A2 zoned) and technical expertise for standardized husbandry, breeding, experimental use of rodent and health monitoring (SPF and SOPF zones) in compliance with regulatory and ethical guidelines. The platform offers technical services such as Surgery on brain and spinal cord, Behavioral tests (anxiety, depression, cognition, motor/locomotor and visual parameters, spontaneous activity, USV recording etc… ), embryo transfer. Training and technical support are available for rodent handling, experimental design, and data reproducibility.

Proper citation: Paris Brain Institute PhenoICMice Core Facility (RRID:SCR_028531) Copy   

•   Source: SciCrunch Registry

https://nyulangone.sharepoint.com/sites/pophealth-data-hub

Core to improve access, efficiency, and support for research teams working with a wide range of data sources to study and address population health issues. Part of data ecosystem of research data hubs and related services at NYULH. Our goal is to help Population Health PIs and Analysts solve their administrative and analysis issues. This includes data acquisition, storage, cleaning, analysis, and dissemination.

Proper citation: New York University Langone Health NYULH Population Health Data Hub Core Facility (RRID:SCR_028492) Copy   

•   Source: SciCrunch Registry

http://www.lvvc.be

Core provides services in design, construction, and production of custom research grade viral vectors for biomedical research including Adeno-associated viral (AAV) vectors, Retroviral vectors (MLV-based), Lentiviral vectors (LV), Virus-Like Particles (VLPs / Nanoblades).

Proper citation: Catholic University of Leuven Viral Vector Core Facility (RRID:SCR_028527) Copy   

•   Source: SciCrunch Registry